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Items: 13


A practical workflow for capillary microsampling in nonclinical studies.

Wang L, Wang B, Chadwick KD, Su T, Mangipudy R, Pillutla RC, Ji QC.

Bioanalysis. 2019 Feb 15. doi: 10.4155/bio-2018-0224. [Epub ahead of print]


Landscape evolution and nutrient rejuvenation reflected in Amazon forest canopy chemistry.

Chadwick KD, Asner GP.

Ecol Lett. 2018 Jul;21(7):978-988. doi: 10.1111/ele.12963. Epub 2018 Apr 16.


Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats.

Tirmenstein M, Janovitz E, Dorr T, Song Y, Chen SJ, Granaldi K, Chadwick KD, Mangipudy R, Graziano M, Attalla B, Haile S, Czajkowski M, Foster JR, Bergholm AM, Billger M, Söderberg M.

Toxicol Pathol. 2018 Feb;46(2):147-157. doi: 10.1177/0192623318756004.


Nonclinical and clinical pharmacology evidence for cardiovascular safety of saxagliptin.

Pollack PS, Chadwick KD, Smith DM, Billger M, Hirshberg B, Iqbal N, Boulton DW.

Cardiovasc Diabetol. 2017 Sep 13;16(1):113. doi: 10.1186/s12933-017-0595-6. Review.


Targeted carbon conservation at national scales with high-resolution monitoring.

Asner GP, Knapp DE, Martin RE, Tupayachi R, Anderson CB, Mascaro J, Sinca F, Chadwick KD, Higgins M, Farfan W, Llactayo W, Silman MR.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5016-22. doi: 10.1073/pnas.1419550111. Epub 2014 Nov 10.


Quantitative analysis of polyethylene glycol (PEG) and PEGylated proteins in animal tissues by LC-MS/MS coupled with in-source CID.

Gong J, Gu X, Achanzar WE, Chadwick KD, Gan J, Brock BJ, Kishnani NS, Humphreys WG, Iyer RA.

Anal Chem. 2014 Aug 5;86(15):7642-9. doi: 10.1021/ac501507g. Epub 2014 Jul 8.


The glucagon-like peptide-1-based therapeutics exenatide and saxagliptin did not cause detrimental effects on the pancreas in mice, rats, dogs and monkeys.

Roy D, Chadwick KD, Tatarkiewicz K, LaCerte C, Bergholm AM, Brodie T, Mangipudy RS, Parkes D, Graziano MJ, Reilly TP.

Diabetes Obes Metab. 2014 Oct;16(10):910-21. doi: 10.1111/dom.12294. Epub 2014 Apr 27.


A tale of two "forests": random forest machine learning AIDS tropical forest carbon mapping.

Mascaro J, Asner GP, Knapp DE, Kennedy-Bowdoin T, Martin RE, Anderson C, Higgins M, Chadwick KD.

PLoS One. 2014 Jan 28;9(1):e85993. doi: 10.1371/journal.pone.0085993. eCollection 2014.


Occurrence of spontaneous pancreatic lesions in normal and diabetic rats: a potential confounding factor in the nonclinical assessment of GLP-1-based therapies.

Chadwick KD, Fletcher AM, Parrula MC, Bonner-Weir S, Mangipudy RS, Janovitz E, Graziano MJ, Roy D, Reilly TP.

Diabetes. 2014 Apr;63(4):1303-14. doi: 10.2337/db13-1268. Epub 2013 Nov 12.


DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues.

Harstad EB, Rosenblum JS, Gorrell MD, Achanzar WE, Minimo L, Wu J, Rosini-Marthaler L, Gullo R, Ordway ND, Kirby MS, Chadwick KD, Cosma GN, Moyer CF.

Regul Pept. 2013 Sep 10;186:26-35. doi: 10.1016/j.regpep.2013.07.003. Epub 2013 Jul 12.


Human and environmental controls over aboveground carbon storage in Madagascar.

Asner GP, Clark JK, Mascaro J, Vaudry R, Chadwick KD, Vieilledent G, Rasamoelina M, Balaji A, Kennedy-Bowdoin T, Maatoug L, Colgan MS, Knapp DE.

Carbon Balance Manag. 2012 Jan 30;7:2. doi: 10.1186/1750-0680-7-2.


Fifty years of "the pill": risk reduction and discovery of benefits beyond contraception, reflections, and forecast.

Chadwick KD, Burkman RT, Tornesi BM, Mahadevan B.

Toxicol Sci. 2012 Jan;125(1):2-9. doi: 10.1093/toxsci/kfr242. Epub 2011 Sep 22.


Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections.

Fura A, Khanna A, Vyas V, Koplowitz B, Chang SY, Caporuscio C, Boulton DW, Christopher LJ, Chadwick KD, Hamann LG, Humphreys WG, Kirby M.

Drug Metab Dispos. 2009 Jun;37(6):1164-71. doi: 10.1124/dmd.108.026088. Epub 2009 Feb 27.


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