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Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture.

Kelly RA, Leedale J, Harrell A, Beard DA, Randle LE, Chadwick AE, Webb SD.

PLoS One. 2018 Nov 29;13(11):e0207803. doi: 10.1371/journal.pone.0207803. eCollection 2018.


Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters.

Mehibel M, Ortiz-Martinez F, Voelxen N, Boyers A, Chadwick A, Telfer BA, Mueller-Klieser W, West CM, Critchlow SE, Williams KJ, Stratford IJ.

Sci Rep. 2018 Nov 14;8(1):16804. doi: 10.1038/s41598-018-35103-1.


Beyond scattering and absorption: Perceptual unmixing of translucent liquids.

Chadwick AC, Cox G, Smithson HE, Kentridge RW.

J Vis. 2018 Oct 1;18(11):18. doi: 10.1167/18.11.18.


In utero CRISPR-mediated therapeutic editing of metabolic genes.

Rossidis AC, Stratigis JD, Chadwick AC, Hartman HA, Ahn NJ, Li H, Singh K, Coons BE, Li L, Lv W, Zoltick PW, Alapati D, Zacharias W, Jain R, Morrisey EE, Musunuru K, Peranteau WH.

Nat Med. 2018 Oct;24(10):1513-1518. doi: 10.1038/s41591-018-0184-6. Epub 2018 Oct 8.


Using the health belief model to identify communication opportunities to prevent Chagas disease in Southern Ecuador.

Patterson NM, Bates BR, Chadwick AE, Nieto-Sanchez C, Grijalva MJ.

PLoS Negl Trop Dis. 2018 Sep 27;12(9):e0006841. doi: 10.1371/journal.pntd.0006841. eCollection 2018 Sep.


Tuning Antisite Defect Density in Perovskite-BaLiF3 via Cycling between Ball Milling and Heating.

Düvel A, Morgan LM, Cibin G, Pickup D, Chadwick AV, Heitjans P, Sayle DC.

J Phys Chem Lett. 2018 Sep 6;9(17):5121-5124. doi: 10.1021/acs.jpclett.8b01915. Epub 2018 Aug 27.


Alkaline-Earth Rhodium Hydroxides: Synthesis, Structures, and Thermal Decomposition to Complex Oxides.

Cook DS, Clarkson GJ, Dawson DM, Ashbrook SE, Fisher JM, Thompsett D, Pickup DM, Chadwick AV, Walton RI.

Inorg Chem. 2018 Sep 4;57(17):11217-11224. doi: 10.1021/acs.inorgchem.8b01797. Epub 2018 Aug 14.


The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity.

Kamalian L, Douglas O, Jolly CE, Snoeys J, Simic D, Monshouwer M, Williams DP, Kevin Park B, Chadwick AE.

Toxicol In Vitro. 2018 Dec;53:136-147. doi: 10.1016/j.tiv.2018.08.001. Epub 2018 Aug 7.


Distinct learning-induced changes in stimulus selectivity and interactions of GABAergic interneuron classes in visual cortex.

Khan AG, Poort J, Chadwick A, Blot A, Sahani M, Mrsic-Flogel TD, Hofer SB.

Nat Neurosci. 2018 Jun;21(6):851-859. doi: 10.1038/s41593-018-0143-z. Epub 2018 May 21.


Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3.

Chadwick AC, Evitt NH, Lv W, Musunuru K.

Circulation. 2018 Feb 27;137(9):975-977. doi: 10.1161/CIRCULATIONAHA.117.031335. No abstract available.


Oxygen redox chemistry without excess alkali-metal ions in Na2/3[Mg0.28Mn0.72]O2.

Maitra U, House RA, Somerville JW, Tapia-Ruiz N, Lozano JG, Guerrini N, Hao R, Luo K, Jin L, Pérez-Osorio MA, Massel F, Pickup DM, Ramos S, Lu X, McNally DE, Chadwick AV, Giustino F, Schmitt T, Duda LC, Roberts MR, Bruce PG.

Nat Chem. 2018 Mar;10(3):288-295. doi: 10.1038/nchem.2923. Epub 2018 Jan 22.


Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer.

Latif A, Chadwick AL, Kitson SJ, Gregson HJ, Sivalingam VN, Bolton J, McVey RJ, Roberts SA, Marshall KM, Williams KJ, Stratford IJ, Crosbie EJ.

BMC Clin Pathol. 2017 Dec 28;17:27. doi: 10.1186/s12907-017-0067-7. eCollection 2017.


Corrigendum: Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome.

Atiomo W, Shafiee MN, Chapman C, Metzler VM, Abouzeid J, Latif A, Chadwick A, Kitson S, Sivalingam VN, Stratford IJ, Rutland CS, Persson JL, Ødum N, Fuentes-Utrilla P, Jeyapalan JN, Heery DM, Crosbie EJ, Mongan NP.

Clin Endocrinol (Oxf). 2017 Dec;87(6):886. doi: 10.1111/cen.13515. No abstract available.


Translucence perception is not dependent on cortical areas critical for processing colour or texture.

Chadwick AC, Heywood CA, Smithson HE, Kentridge RW.

Neuropsychologia. 2017 Nov 15. pii: S0028-3932(17)30422-0. doi: 10.1016/j.neuropsychologia.2017.11.009. [Epub ahead of print]


Development of a Modified-Release Formulation of Lovastatin Targeted to Intestinal Methanogens Implicated in Irritable Bowel Syndrome With Constipation.

Hubert S, Chadwick A, Wacher V, Coughlin O, Kokai-Kun J, Bristol A.

J Pharm Sci. 2018 Feb;107(2):662-671. doi: 10.1016/j.xphs.2017.09.028. Epub 2017 Oct 6.


High rates of respiratory symptoms and airway disease in mental health inpatients in a tertiary centre.

Burke AJ, Hay K, Chadwick A, Siskind D, Sheridan J.

Intern Med J. 2018 Apr;48(4):433-438. doi: 10.1111/imj.13594.


CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia.

Chadwick AC, Musunuru K.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):12-18. doi: 10.1161/ATVBAHA.117.309326. Epub 2017 Aug 24. Review.


In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.

Chadwick AC, Wang X, Musunuru K.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1741-1747. doi: 10.1161/ATVBAHA.117.309881. Epub 2017 Jul 27.


Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome.

Atiomo W, Shafiee MN, Chapman C, Metzler VM, Abouzeid J, Latif A, Chadwick A, Kitson S, Sivalingam VN, Stratford IJ, Rutland CS, Persson JL, Ødum N, Fuentes-Utrilla P, Jeyapalan JN, Heery DM, Crosbie EJ, Mongan NP.

Clin Endocrinol (Oxf). 2017 Nov;87(5):557-565. doi: 10.1111/cen.13436. Epub 2017 Aug 18. Erratum in: Clin Endocrinol (Oxf). 2017 Dec;87(6):886.


Phosphate Ion Functionalization of Perovskite Surfaces for Enhanced Oxygen Evolution Reaction.

Yang C, Laberty-Robert C, Batuk D, Cibin G, Chadwick AV, Pimenta V, Yin W, Zhang L, Tarascon JM, Grimaud A.

J Phys Chem Lett. 2017 Aug 3;8(15):3466-3472. doi: 10.1021/acs.jpclett.7b01504. Epub 2017 Jul 13.


Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing.

Chadwick AC, Musunuru K.

Curr Atheroscler Rep. 2017 Jul;19(7):32. doi: 10.1007/s11883-017-0668-8. Review.


Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention.

Yang M, Chadwick AE, Dart C, Kamishima T, Quayle JM.

PLoS One. 2017 May 19;12(5):e0177951. doi: 10.1371/journal.pone.0177951. eCollection 2017.


Is Geometric Frustration-Induced Disorder a Recipe for High Ionic Conductivity?

Düvel A, Heitjans P, Fedorov P, Scholz G, Cibin G, Chadwick AV, Pickup DM, Ramos S, Sayle LWL, Sayle EKL, Sayle TXT, Sayle DC.

J Am Chem Soc. 2017 Apr 26;139(16):5842-5848. doi: 10.1021/jacs.7b00502. Epub 2017 Apr 14.


Half-and-half nails in a patient on antituberculosis treatment.

Chadwick A, Thwaites V, Holland M, Shahidi M.

BMJ Case Rep. 2017 Mar 24;2017. pii: bcr2017219841. doi: 10.1136/bcr-2017-219841. No abstract available.


Genome Editing for the Study of Cardiovascular Diseases.

Chadwick AC, Musunuru K.

Curr Cardiol Rep. 2017 Mar;19(3):22. doi: 10.1007/s11886-017-0830-5. Review.


Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labeling in macrophages for magnetic resonance-based detection in vivo.

Sharkey J, Starkey Lewis PJ, Barrow M, Alwahsh SM, Noble J, Livingstone E, Lennen RJ, Jansen MA, Carrion JG, Liptrott N, Forbes S, Adams DJ, Chadwick AE, Forbes SJ, Murray P, Rosseinsky MJ, Goldring CE, Park BK.

Cytotherapy. 2017 Apr;19(4):555-569. doi: 10.1016/j.jcyt.2017.01.003. Epub 2017 Feb 15.


NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif.

Chadwick AC, Jensen DR, Hanson PJ, Lange PT, Proudfoot SC, Peterson FC, Volkman BF, Sahoo D.

Structure. 2017 Mar 7;25(3):446-457. doi: 10.1016/j.str.2017.01.001. Epub 2017 Feb 2.


Flexible theta sequence compression mediated via phase precessing interneurons.

Chadwick A, van Rossum MC, Nolan MF.

Elife. 2016 Dec 8;5. pii: e20349. doi: 10.7554/eLife.20349.


Dendrites and Pits: Untangling the Complex Behavior of Lithium Metal Anodes through Operando Video Microscopy.

Wood KN, Kazyak E, Chadwick AF, Chen KH, Zhang JG, Thornton K, Dasgupta NP.

ACS Cent Sci. 2016 Nov 23;2(11):790-801. Epub 2016 Oct 14.


Anion Redox Chemistry in the Cobalt Free 3d Transition Metal Oxide Intercalation Electrode Li[Li0.2Ni0.2Mn0.6]O2.

Luo K, Roberts MR, Guerrini N, Tapia-Ruiz N, Hao R, Massel F, Pickup DM, Ramos S, Liu YS, Guo J, Chadwick AV, Duda LC, Bruce PG.

J Am Chem Soc. 2016 Sep 7;138(35):11211-8. doi: 10.1021/jacs.6b05111. Epub 2016 Aug 24.


Developing confidence in mental health students to recognise and manage physical health problems using a learning intervention.

Chadwick AL, Withnell N.

Nurse Educ Pract. 2016 Jul;19:25-30. doi: 10.1016/j.nepr.2016.04.002. Epub 2016 Apr 16.


Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells.

Ball AL, Kamalian L, Alfirevic A, Lyon JJ, Chadwick AE.

Toxicol Sci. 2016 Oct;153(2):341-51. doi: 10.1093/toxsci/kfw126. Epub 2016 Jul 13.


Experimental river delta size set by multiple floods and backwater hydrodynamics.

Ganti V, Chadwick AJ, Hassenruck-Gudipati HJ, Fuller BM, Lamb MP.

Sci Adv. 2016 May 20;2(5):e1501768. doi: 10.1126/sciadv.1501768. eCollection 2016 May.


Charge-compensation in 3d-transition-metal-oxide intercalation cathodes through the generation of localized electron holes on oxygen.

Luo K, Roberts MR, Hao R, Guerrini N, Pickup DM, Liu YS, Edström K, Guo J, Chadwick AV, Duda LC, Bruce PG.

Nat Chem. 2016 Jul;8(7):684-91. doi: 10.1038/nchem.2471. Epub 2016 Mar 21.


Metabolic reprogramming of bone marrow stromal cells by leukemic extracellular vesicles in acute lymphoblastic leukemia.

Johnson SM, Dempsey C, Chadwick A, Harrison S, Liu J, Di Y, McGinn OJ, Fiorillo M, Sotgia F, Lisanti MP, Parihar M, Krishnan S, Saha V.

Blood. 2016 Jul 21;128(3):453-6. doi: 10.1182/blood-2015-12-688051. Epub 2016 Apr 20. No abstract available.


Communication and Stress: Effects of Hope Evocation and Rumination Messages on Heart Rate, Anxiety, and Emotions After a Stressor.

Chadwick AE, Zoccola PM, Figueroa WS, Rabideau EM.

Health Commun. 2016 Dec;31(12):1447-59. doi: 10.1080/10410236.2015.1079759. Epub 2016 Apr 7.


Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.

Heslop JA, Rowe C, Walsh J, Sison-Young R, Jenkins R, Kamalian L, Kia R, Hay D, Jones RP, Malik HZ, Fenwick S, Chadwick AE, Mills J, Kitteringham NR, Goldring CE, Kevin Park B.

Arch Toxicol. 2017 Jan;91(1):439-452. doi: 10.1007/s00204-016-1694-y. Epub 2016 Apr 2.


Response to Letter to the Editor from Ackerman MJ, et al.

Hefti MM, Kinney HC, Cryan JB, Haas EA, Chadwick AE, Trachtenberg FL, Armstrong DD, Grafe M, Krous HF.

Forensic Sci Med Pathol. 2016 Jun;12(2):232-5. doi: 10.1007/s12024-016-9772-2. Epub 2016 Mar 29. No abstract available.


Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria.

Alnabulsi S, Santina E, Russo I, Hussein B, Kadirvel M, Chadwick A, Bichenkova EV, Bryce RA, Nolan K, Demonacos C, Stratford IJ, Freeman S.

Eur J Med Chem. 2016 Mar 23;111:33-45. doi: 10.1016/j.ejmech.2016.01.022. Epub 2016 Jan 21.


Hippocampal malformation associated with sudden death in early childhood: a neuropathologic study: Part 2 of the investigations of The San Diego SUDC Research Project.

Hefti MM, Cryan JB, Haas EA, Chadwick AE, Crandall LA, Trachtenberg FL, Armstrong DD, Grafe M, Krous HF, Kinney HC.

Forensic Sci Med Pathol. 2016 Mar;12(1):14-25. doi: 10.1007/s12024-015-9731-3. Epub 2016 Jan 19.


Sudden unexpected death in early childhood: general observations in a series of 151 cases: Part 1 of the investigations of the San Diego SUDC Research Project.

Hefti MM, Kinney HC, Cryan JB, Haas EA, Chadwick AE, Crandall LA, Trachtenberg FL, Armstrong DD, Grafe M, Krous HF.

Forensic Sci Med Pathol. 2016 Mar;12(1):4-13. doi: 10.1007/s12024-015-9724-2. Epub 2016 Jan 19.


Low yield of unselected testing in patients with acutely abnormal liver function tests.

Chadwick A, Marks M.

JRSM Open. 2015 Dec 2;7(1):2054270415611309. doi: 10.1177/2054270415611309. eCollection 2016 Jan.


From Darzi to Keogh: are doctors under 'report fatigue'.

Chadwick A, Mohabir A.

Clin Med (Lond). 2015 Dec;15(6):597-8. doi: 10.7861/clinmedicine.15-6-597. No abstract available.


Climate Change, Health, and Communication: A Primer.

Chadwick AE.

Health Commun. 2016;31(6):782-5. doi: 10.1080/10410236.2014.1002030. Epub 2015 Nov 18.


Accidental overdose in the deep shade of night: a warning on the assumed safety of 'natural substances'.

Chadwick A, Ash A, Day J, Borthwick M.

BMJ Case Rep. 2015 Nov 5;2015. pii: bcr2015209333. doi: 10.1136/bcr-2015-209333.


Intercostal chest drains: Are you confident going on the pull? If not use the I-T-U approach.

Chadwick AJ, Halfyard R, Ali M.

J Intensive Care Soc. 2015 Nov;16(4):312-325. doi: 10.1177/1751143715583856. Epub 2015 Apr 29.


How to administer intramuscular injections.

Chadwick A, Withnell N.

Nurs Stand. 2015 Oct 21;30(8):36-9. doi: 10.7748/ns.30.8.36.s45. No abstract available.


Oxidized LDL-bound CD36 recruits an Na⁺/K⁺-ATPase-Lyn complex in macrophages that promotes atherosclerosis.

Chen Y, Kennedy DJ, Ramakrishnan DP, Yang M, Huang W, Li Z, Xie Z, Chadwick AC, Sahoo D, Silverstein RL.

Sci Signal. 2015 Sep 8;8(393):ra91. doi: 10.1126/scisignal.aaa9623. Erratum in: Sci Signal. 2015 Oct 6;8(397):er7.


Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress.

Korytowski W, Wawak K, Pabisz P, Schmitt JC, Chadwick AC, Sahoo D, Girotti AW.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2104-13. doi: 10.1161/ATVBAHA.115.306210. Epub 2015 Aug 27.


Global database of paleocurrent trends through the Phanerozoic and Precambrian.

Brand L, Wang M, Chadwick A.

Sci Data. 2015 Jun 9;2:150025. doi: 10.1038/sdata.2015.25. eCollection 2015.

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