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Running Out of Time: Facilitating Off Label Approval in Cancer Treatment.
Mendivil AA, Chad JA, Goldstein BH.
J Clin Pharmacol. 2019 May;59(5):771-772. doi: 10.1002/jcph.1404. Epub 2019 Mar 7. No abstract available.
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The First Ejaculation: A Male Pubertal Milestone Comparable to Menarche?
Chad JA.
J Sex Res. 2018 Nov 30:1-9. doi: 10.1080/00224499.2018.1543643. [Epub ahead of print]
Re-examining age-related differences in white matter microstructure with free-water corrected diffusion tensor imaging.
Chad JA, Pasternak O, Salat DH, Chen JJ.
Neurobiol Aging. 2018 Nov;71:161-170. doi: 10.1016/j.neurobiolaging.2018.07.018. Epub 2018 Aug 1.
Mechano-sensitization of mammalian neuronal networks through expression of the bacterial large-conductance mechanosensitive ion channel.
Soloperto A, Boccaccio A, Contestabile A, Moroni M, Hallinan GI, Palazzolo G, Chad J, Deinhardt K, Carugo D, Difato F.
J Cell Sci. 2018 Mar 8;131(5). pii: jcs210393. doi: 10.1242/jcs.210393.
Ptychographic coherent diffractive imaging with orthogonal probe relaxation.
Odstrcil M, Baksh P, Boden SA, Card R, Chad JE, Frey JG, Brocklesby WS.
Opt Express. 2016 Apr 18;24(8):8360-9. doi: 10.1364/OE.24.008360.
Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines.
Ring A, Strom BO, Turner SR, Timperley CM, Bird M, Green AC, Chad JE, Worek F, Tattersall JE.
PLoS One. 2015 Aug 14;10(8):e0135811. doi: 10.1371/journal.pone.0135811. eCollection 2015.
Colorectal cancer screening practices in Saskatchewan: Survey of family physicians.
Deobald R, Graham P, Chad J, Di Gregorio C, Johnstone J, Balbuena L, Kenyon C, Lees M.
Can Fam Physician. 2013 Dec;59(12):e558-63.
A super-oscillatory lens optical microscope for subwavelength imaging.
Rogers ET, Lindberg J, Roy T, Savo S, Chad JE, Dennis MR, Zheludev NI.
Nat Mater. 2012 Mar 25;11(5):432-5. doi: 10.1038/nmat3280.
An unusual case of fallopian tube intraepithelial carcinoma with mucinous goblet cell differentiation.
Mendivil AA, Stallman JM, Chad JN, Goldstein BH.
Gynecol Oncol Case Rep. 2012 Jan 20;2(2):47-50. doi: 10.1016/j.gynor.2012.01.002. eCollection 2012.
Protection against nerve agent poisoning by a noncompetitive nicotinic antagonist.
Turner SR, Chad JE, Price M, Timperley CM, Bird M, Green AC, Tattersall JE.
Toxicol Lett. 2011 Sep 25;206(1):105-11. doi: 10.1016/j.toxlet.2011.05.1035. Epub 2011 May 27.
In vitro CNS tissue analogues formed by self-organisation of reaggregated post-natal brain tissue.
Bailey JL, O'Connor V, Hannah M, Hewlett L, Biggs TE, Sundstrom LE, Findlay MW, Chad JE.
J Neurochem. 2011 Jun;117(6):1020-32. doi: 10.1111/j.1471-4159.2011.07276.x. Epub 2011 May 19.
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.
Chad JM, Sarathy KP, Gruber TD, Addala E, Kiessling LL, Sanders DA.
Biochemistry. 2007 Jun 12;46(23):6723-32. Epub 2007 May 19.
Kainic acid induces rapid cell death followed by transiently reduced cell proliferation in the immature granule cell layer of rat organotypic hippocampal slice cultures.
Sadgrove MP, Chad JE, Gray WP.
Brain Res. 2005 Feb 28;1035(2):111-9.
Intraischaemic hypothermia reduces free radical production and protects against ischaemic insults in cultured hippocampal slices.
McManus T, Sadgrove M, Pringle AK, Chad JE, Sundstrom LE.
J Neurochem. 2004 Oct;91(2):327-36.
Sarco/endoplasmic-reticulum calcium ATPase SERCA1 is maintained in the endoplasmic reticulum by a retrieval signal located between residues 1 and 211.
Newton T, Black JP, Butler J, Lee AG, Chad J, East JM.
Biochem J. 2003 May 1;371(Pt 3):775-82.
4,5-diaminofluoroscein imaging of nitric oxide synthesis in crayfish terminal ganglia.
Schuppe H, Cuttle M, Chad JE, Newland PL.
J Neurobiol. 2002 Nov 15;53(3):361-9.
A large-scale simulation of the piriform cortex by a cell automaton-based network model.
Claverol ET, Brown AD, Chad JE.
IEEE Trans Biomed Eng. 2002 Sep;49(9):921-35.
Involvement of ryanodine receptors in EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in helix lucorum identified neurones.
Pivovarov AS, Chad JE, Walker RJ.
Regul Pept. 2000 Mar 17;88(1-3):83-93.
Reduced Mg2+ blockade of synaptically activated N-methyl-D-aspartate receptor-channels in CA1 pyramidal neurons in kainic acid-lesioned rat hippocampus.
Chen Y, Chad JE, Cannon RC, Wheal HV.
Neuroscience. 1999;88(3):727-39.
Role of ERK1/ERK2 and p70S6K pathway in insulin signalling of protein synthesis.
Sale EM, Atkinson PP, Arnott CH, Chad JE, Sale GJ.
FEBS Lett. 1999 Mar 5;446(1):122-6.
The actions of muscle relaxants at nicotinic acetylcholine receptor isoforms.
Garland CM, Foreman RC, Chad JE, Holden-Dye L, Walker RJ.
Eur J Pharmacol. 1998 Sep 11;357(1):83-92.
Identification of endoplasmic reticulum targeting signals using SERCA/PMCA chimeras.
Black JP, Chad JE, Lee AG, East JM.
Biochem Soc Trans. 1998 Aug;26(3):S299. No abstract available.
Localization of endoplasmic reticulum in living cells using green fluorescent protein chimeras.
van Goethem ID, Adams P, Chad JE, Mather AM, Griffiths B, Lee AG, East JM.
Biochem Soc Trans. 1998 Aug;26(3):S298. No abstract available.
BipA affects Ca++ fluxes and phosphorylation of the translocated intimin receptor (Tir/Hp90) in host epithelial cells infected with enteropathogenic E. coli.
Farris M, Grant A, Jane S, Chad J, O'Connor CD.
Biochem Soc Trans. 1998 Aug;26(3):S225. No abstract available.
Pro-epileptic changes in synaptic function can be accompanied by pro-epileptic changes in neuronal excitability.
Wheal HV, Bernard C, Chad JE, Cannon RC.
Trends Neurosci. 1998 Apr;21(4):167-74. Review.
Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia.
Pringle AK, Iannotti F, Wilde GJ, Chad JE, Seeley PJ, Sundstrom LE.
Brain Res. 1997 Apr 25;755(1):36-46.
Location of endoplasmic reticulum relative to sarcoplasmic reticulum in cultured chick myotubes.
van Goethem ID, Chad J, Lee AG, Jane SD, East JM.
Biochem Soc Trans. 1997 Feb;25(1):9S. No abstract available.
Synaptic release rather than failure in the conditioning pulse results in paired-pulse facilitation during minimal synaptic stimulation in the rat hippocampal CA1 neurones.
Chen Y, Chad JE, Wheal HV.
Neurosci Lett. 1996 Nov 8;218(3):204-8.
Activation of nicotinic acetylcholine receptors expressed in quail fibroblasts: effects on intracellular calcium.
Cross KM, Jane SD, Wild AE, Foreman RC, Chad JE.
Br J Pharmacol. 1995 Dec;116(7):2838-44.
Stimulation of endocytosis in mouse blastocysts by insulin: a quantitative morphological analysis.
Dunglison GF, Jane SD, McCaul TF, Chad JE, Fleming TP, Kaye PL.
J Reprod Fertil. 1995 Sep;105(1):115-23.
Increased perinuclear Ca2+ activity evoked by metabotropic glutamate receptor activation in rat hippocampal neurones.
Phenna S, Jane SD, Chad JE.
J Physiol. 1995 Jul 1;486 ( Pt 1):149-61.
Bicuculline enhances the late GABAB receptor-mediated paired-pulse inhibition observed in rat hippocampal slices.
Stanford IM, Wheal HV, Chad JE.
Eur J Pharmacol. 1995 Apr 24;277(2-3):229-34.
Enhancement by 5-hydroxytryptamine and analogues of desensitization of neuronal and muscle nicotinic receptors expressed in Xenopus oocytes.
Cross KM, Foreman RC, Chad JE.
Br J Pharmacol. 1995 Apr;114(8):1636-40.
2-Hydroxy-saclofen causes a phaclofen-reversible reduction in population spike amplitude in the rat hippocampal slice.
Caddick SJ, Stanford IM, Chad JE.
Eur J Pharmacol. 1995 Feb 14;274(1-3):41-6.
Membrane clustering and bungarotoxin binding by the nicotinic acetylcholine receptor: role of the beta subunit.
Wheeler SV, Jane SD, Cross KM, Chad JE, Foreman RC.
J Neurochem. 1994 Nov;63(5):1891-9.
Residues 1 to 80 of the N-terminal domain of the beta subunit confer neuronal bungarotoxin sensitivity and agonist selectivity on neuronal nicotinic receptors.
Wheeler SV, Chad JE, Foreman R.
FEBS Lett. 1993 Oct 11;332(1-2):139-42.
Inactivation of calcium channels.
Chad J.
Comp Biochem Physiol A Comp Physiol. 1989;93(1):95-105. Review.
The role of cyclic AMP-dependent phosphorylation in the maintenance and modulation of voltage-activated calcium channels.
Chad J, Kalman D, Armstrong D.
Soc Gen Physiol Ser. 1987;42:167-86. Review.
An enzymatic mechanism for calcium current inactivation in dialysed Helix neurones.
Chad JE, Eckert R.
J Physiol. 1986 Sep;378:31-51.
Enzymatic regulation of calcium current in dialyzed and intact molluscan neurons.
Eckert R, Chad JE, Kalman D.
J Physiol (Paris). 1986;81(4):318-24.
Calcium domains associated with individual channels can account for anomalous voltage relations of CA-dependent responses.
Biophys J. 1984 May;45(5):993-9.
Kinetics of calcium-dependent inactivation of calcium current in voltage-clamped neurones of Aplysia californica.
Chad J, Eckert R, Ewald D.
J Physiol. 1984 Feb;347:279-300.
Inactivation of Ca channels.
Eckert R, Chad JE.
Prog Biophys Mol Biol. 1984;44(3):215-67. Review. No abstract available.
The acetylcholine induced membrane current fluctuations are characteristic of the receptor-ionophore population involved.
Chad JE, Kerkut GA.
Comp Biochem Physiol C. 1981;68C(1):35-42. No abstract available.
Ramped voltage clamp study of the action of acetylcholine on three types of neurons in the snail (Helix aspersa) brain.
Chad JE, Kerkut GA, Walker RJ.
Comp Biochem Physiol C. 1979;63C(2):269-78. No abstract available.
Triangular ramp clamping of Helix neurones during acetylcholine application [proceedings].
J Physiol. 1977 Feb;265(1):44P. No abstract available.
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