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TAZ functions as a tumor suppressor in multiple myeloma by downregulating MYC.

Grieve S, Wajnberg G, Lees M, Chacko S, Weir J, Crapoulet N, Reiman T.

Blood Adv. 2019 Nov 26;3(22):3613-3625. doi: 10.1182/bloodadvances.2019000374.


Structure Based Multitargeted Molecular Docking Analysis of Selected Furanocoumarins against Breast Cancer.

Acharya R, Chacko S, Bose P, Lapenna A, Pattanayak SP.

Sci Rep. 2019 Oct 31;9(1):15743. doi: 10.1038/s41598-019-52162-0.


Hydrogenated-Graphene-Encapsulated Graphene: A Versatile Material for Device Applications.

Ghadiyali M, Chacko S.

ACS Omega. 2019 Oct 7;4(17):17494-17503. doi: 10.1021/acsomega.9b02329. eCollection 2019 Oct 22.


Laparoscopic low anterior resection for rectal bleeding in Klippel-Trénaunay syndrome - a video vignette.

Veerankutty FH, Subrahmanya P, Chacko S, Sreekumar VI, Kamalesh NP, Kurumboor P.

Colorectal Dis. 2019 Oct 24. doi: 10.1111/codi.14885. [Epub ahead of print] No abstract available.


Rifampicin, Not Vitamin E, Suppresses Parenteral Nutrition Associated Liver Disease Development through Pregnane X Receptor Pathway in Piglets.

Guthrie G, Stoll B, Chacko S, Lauridsen C, Plat J, Burrin DG.

Am J Physiol Gastrointest Liver Physiol. 2019 Oct 11. doi: 10.1152/ajpgi.00193.2019. [Epub ahead of print]


Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans.

Chacko SA, Ly VT, Christopher LJ, Gan J.

Xenobiotica. 2019 Oct 10:1-9. doi: 10.1080/00498254.2019.1675100. [Epub ahead of print]


Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats.

Blesson CS, Schutt A, Chacko S, Marini JC, Mathew PR, Tanchico D, Balakrishnan M, Yallampalli C.

Front Endocrinol (Lausanne). 2019 Aug 6;10:538. doi: 10.3389/fendo.2019.00538. eCollection 2019.


Smartphone electrocardiograms reveal painful left bundle branch block syndrome and illustrate associated electrophysiological phenomena.

García-Niebla J, Crinion D, Gutierrez G, Chacko S, Lacalzada-Almeida J, Baranchuk A.

Europace. 2019 Jul 31. pii: euz200. doi: 10.1093/europace/euz200. [Epub ahead of print] No abstract available.


Deactivation of Implantable Cardioverter Defibrillator in Patients With Terminal Diagnoses.

Trussler A, Alexander B, Campbell D, Alhammad N, Enriquez A, Chacko S, Garrett T, Simpson C, Redfearn D, Abdollah H, Herx L, Baranchuk A.

Am J Cardiol. 2019 Oct 1;124(7):1064-1068. doi: 10.1016/j.amjcard.2019.07.007. Epub 2019 Jul 15.


A quaint masquerader of breast cancer: Paraneoplastic cerebellar degeneration.

Chacko S, Joseph R, Manoharan AT, M V.

Neurol India. 2019 May-Jun;67(3):892-894. doi: 10.4103/0028-3886.263186. No abstract available.


Antiprogesterone therapy in recurrent meningiomas: A disappointing end to four decades of research?

Chacko SR, Chacko AG.

Neurol India. 2019 May-Jun;67(3):706-707. doi: 10.4103/0028-3886.263217. No abstract available.


High-resolution mapping of the atria using the HD Grid catheter.

Hong KL, Redfearn D, Chacko S, Baley J, Baranchuk A, Glover BM.

HeartRhythm Case Rep. 2019 Jan 23;5(7):351-353. doi: 10.1016/j.hrcr.2018.12.012. eCollection 2019 Jul. No abstract available.


A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor.

Al-Zamel N, Al-Sabah S, Luqmani Y, Adi L, Chacko S, Schneider TD, Krasel C.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3532. doi: 10.3390/ijms20143532.


Cryptic cavity with an unusual drainage.

Paul A, Chacko ST, George PV.

Heart. 2019 Oct;105(19):1499-1524. doi: 10.1136/heartjnl-2019-315141. Epub 2019 Jun 1. No abstract available.


Ambulatory ECG predictors of atrial fibrillation are ineffective in severe sleep apnea.

Yeung C, Crinion D, Hammond S, Chacko S, Enriquez A, Redfearn D, Simpson C, Abdollah H, Baranchuk A.

J Electrocardiol. 2019 Jul - Aug;55:120-122. doi: 10.1016/j.jelectrocard.2019.05.002. Epub 2019 May 8.


Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay.

Deschamps T, Waisner H, Dogrammatzis C, Roy A, Chacko S, Perera C, Prisinzano TE, Kalamvoki M.

J Virol. 2019 Jun 14;93(13). pii: e00619-19. doi: 10.1128/JVI.00619-19. Print 2019 Jul 1.


Congenital methaemoglobinaemia diagnosed in an adolescent boy.

Paul A, Chacko ST.

BMJ Case Rep. 2019 Mar 31;12(3). pii: e228470. doi: 10.1136/bcr-2018-228470.


Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome.

Cade WT, Bohnert KL, Peterson LR, Patterson BW, Bittel AJ, Okunade AL, de Las Fuentes L, Steger-May K, Bashir A, Schweitzer GG, Chacko SK, Wanders RJ, Pacak CA, Byrne BJ, Reeds DN.

J Inherit Metab Dis. 2019 May;42(3):480-493. doi: 10.1002/jimd.12094. Epub 2019 Apr 11.


NF-κB and GATA-Binding Factor 6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy.

Thangavel C, Gomes CM, Zderic SA, Javed E, Addya S, Singh J, Das S, Birbe R, Den RB, Rattan S, Deshpande DA, Penn RB, Chacko S, Boopathi E.

Am J Pathol. 2019 Apr;189(4):847-867. doi: 10.1016/j.ajpath.2018.12.013. Epub 2019 Jan 30.


Palliative care delivery: descriptions of community-based services in Vellore, India, and Seattle, Washington.

Taub JM, Coats H, Coats C, Doorenbos A, Siva R, Sadan V, Alexander G, Immanuel S, Ravindran V, Chacko ST, Nolet R.

Int J Palliat Nurs. 2019 Jan 2;25(1):39-45. doi: 10.12968/ijpn.2019.25.1.39.


Sex Work, Marginalization, and Activism in India.

Vijayakumar G, Panchanadeswaran S, Chacko S.

Arch Sex Behav. 2019 Oct;48(7):1969-1972. doi: 10.1007/s10508-018-1384-3. Epub 2019 Jan 7. No abstract available.


Radiotherapy for patients with cardiovascular implantable electronic devices: an 11-year experience.

Yeung C, Hazim B, Campbell D, Gooding J, Li SX, Tam HK, Hopman WM, Chacko S, Redfearn DP, Simpson C, Abdollah H, Baranchuk A.

J Interv Card Electrophysiol. 2019 Sep;55(3):333-341. doi: 10.1007/s10840-018-0506-0. Epub 2019 Jan 3.


Identification of a circulating miRNA signature in extracellular vesicles collected from amyotrophic lateral sclerosis patients.

Saucier D, Wajnberg G, Roy J, Beauregard AP, Chacko S, Crapoulet N, Fournier S, Ghosh A, Lewis SM, Marrero A, O'Connell C, Ouellette RJ, Morin PJ.

Brain Res. 2019 Apr 1;1708:100-108. doi: 10.1016/j.brainres.2018.12.016. Epub 2018 Dec 12.


Hybrid ablation under intraoperative 3D voltage mapping guidance.

Elbatarny M, Glover B, Baley J, Chacko S, Alhammad N, Bisleri G.

Multimed Man Cardiothorac Surg. 2018 Dec 10;2018. doi: 10.1510/mmcts.2018.061.


Alterations in branched-chain amino acid kinetics in nonobese but insulin-resistant Asian men.

Tan HC, Hsu JW, Khoo CM, Tai ES, Yu S, Chacko S, Lai OF, Jahoor F.

Am J Clin Nutr. 2018 Dec 1;108(6):1220-1228. doi: 10.1093/ajcn/nqy208.


Treating Lyme carditis high-degree AV block using a temporary-permanent pacemaker.

Wang C, Chacko S, Abdollah H, Baranchuk A.

Ann Noninvasive Electrocardiol. 2019 May;24(3):e12599. doi: 10.1111/anec.12599. Epub 2018 Sep 28.


Gluconeogenesis and risk for fasting hyperglycemia in Black and White women.

Chung ST, Courville AB, Onuzuruike AU, Galvan-De La Cruz M, Mabundo LS, DuBose CW, Kasturi K, Cai H, Gharib AM, Walter PJ, Garraffo HM, Chacko S, Haymond MW, Sumner AE.

JCI Insight. 2018 Sep 20;3(18). pii: 121495. doi: 10.1172/jci.insight.121495. eCollection 2018 Sep 20.


Gold-tip versus contact-sensing catheter for cavotricuspid isthmus ablation: A comparative study.

Gül EE, Boles U, Haseeb S, Hopman WM, Chacko S, Simpson C, Abdollah H, Michael K, Baranchuk A, Redfearn D, Glover B.

Turk Kardiyol Dern Ars. 2018 Sep;46(6):464-470. doi: 10.5543/tkda.2018.44025.


One Size Fits All? Ethnicity and Electrocardiographic Criteria for Cardiac Hypertrophy.

Chacko S, Redfearn D.

Can J Cardiol. 2018 Sep;34(9):1104-1107. doi: 10.1016/j.cjca.2018.07.005. Epub 2018 Jul 12. No abstract available.


Recurrent Takotsubo cardiomyopathy in a postmenopausal Indian lady: Is there a pattern?

Sharath Babu NM, Chacko ST, Chacko BR, Irodi A.

J Postgrad Med. 2019 Apr-Jun;65(2):112-115. doi: 10.4103/jpgm.JPGM_383_17.


Exploring minimally invasive options: Laparoscopic transabdominal levator transection for low rectal cancers.

Veerankutty FH, Chacko S, Sreekumar VI, Krishnan P, Varma D, Kurumboor P.

J Minim Access Surg. 2018 Aug 7. doi: 10.4103/jmas.JMAS_130_18. [Epub ahead of print]


Preserved Left Atrial Epicardial Conduction in Regions of Endocardial "Isolation".

Glover BM, Hong KL, Baranchuk A, Bakker D, Chacko S, Bisleri G.

JACC Clin Electrophysiol. 2018 Apr;4(4):557-558. doi: 10.1016/j.jacep.2017.12.009. No abstract available.


Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome.

Surikow SY, Nguyen TH, Stafford I, Chapman M, Chacko S, Singh K, Licari G, Raman B, Kelly DJ, Zhang Y, Waddingham MT, Ngo DT, Bate AP, Chua SJ, Frenneaux MP, Horowitz JD.

JACC Basic Transl Sci. 2018 Apr 18;3(2):213-226. doi: 10.1016/j.jacbts.2017.10.002. eCollection 2018 Apr.


Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.

Chacko S, Boshoff HIM, Singh V, Ferraris DM, Gollapalli DR, Zhang M, Lawson AP, Pepi MJ, Joachimiak A, Rizzi M, Mizrahi V, Cuny GD, Hedstrom L.

J Med Chem. 2018 Jun 14;61(11):4739-4756. doi: 10.1021/acs.jmedchem.7b01839. Epub 2018 May 30.


Comprehensive assessment of insulin resistance in non-obese Asian Indian and Chinese men.

Tan HC, Yew TW, Chacko S, Tai ES, Kovalik JP, Ching J, Myo Thant S, Khoo CM.

J Diabetes Investig. 2018 Nov;9(6):1296-1303. doi: 10.1111/jdi.12844. Epub 2018 Apr 20.


Knowledge Translation to Optimize Adult Inpatient Glycemic Management With Basal Bolus Insulin Therapy and Improve Patient Outcomes.

Helmle KE, Chacko S, Chan T, Drake A, Edwards AL, Moore GE, Philp LC, Popeski N, Roedler RL, Rogers EJR, Zimmermann GL, McKeen J.

Can J Diabetes. 2018 Oct;42(5):505-513.e1. doi: 10.1016/j.jcjd.2017.12.010. Epub 2017 Dec 27.


Carbon dioxide Angiography-Guided Renal-Related Interventions in Patients with Takayasu Arteritis and Renal Insufficiency.

Chacko S, Joseph G, Thomson V, George P, George O, Danda D.

Cardiovasc Intervent Radiol. 2018 Jul;41(7):998-1007. doi: 10.1007/s00270-018-1936-x. Epub 2018 Mar 16.


Correction to: Oncology practitioners' perspectives and practice patterns of post-treatment cancer survivorship care in the Asia-Pacific region: results from the STEP study.

Chan RJ, Yates P, Li Q, Komatsu H, Lopez V, Thandar M, Chacko ST, So WKW, Pongthavornkamol K, Yi M, Pittayapan P, Butcon J, Wyld D, Molassiotis A; STEP study collaborators.

BMC Cancer. 2018 Mar 1;18(1):240. doi: 10.1186/s12885-018-4105-3.


Radiotherapy for Patients with Cardiovascular Implantable Electronic Devices: A Review.

Yeung C, Chacko S, Glover B, Campbell D, Crystal E, Ben-Dov N, Baranchuk A.

Can J Cardiol. 2018 Mar;34(3):244-251. doi: 10.1016/j.cjca.2017.11.023. Epub 2017 Dec 6. Review.


The Heart of the Matter: Cardiac Manifestations of Endocrine Disease.

Binu AJ, Cherian KE, Kapoor N, Chacko ST, George O, Paul TV.

Indian J Endocrinol Metab. 2017 Nov-Dec;21(6):919-925. doi: 10.4103/ijem.IJEM_212_17. Review.


The role of biomarkers in the diagnosis and risk stratification of acute coronary syndrome.

Chacko S, Haseeb S, Glover BM, Wallbridge D, Harper A.

Future Sci OA. 2017 Oct 27;4(1):FSO251. doi: 10.4155/fsoa-2017-0036. eCollection 2018 Jan. Review.


Incidence of diabetes mellitus and factors associated with its development in HIV-positive patients over the age of 50.

Samad F, Harris M, Puskas CM, Ye M, Chia J, Chacko S, Bondy GP, Lima VD, Montaner JS, Guillemi SA.

BMJ Open Diabetes Res Care. 2017 Nov 26;5(1):e000457. doi: 10.1136/bmjdrc-2017-000457. eCollection 2017.


IgG4-Related Disease of the Appendix.

Veerankutty FH, Saleem S, Chacko S, Sreekumar VI, Krishnan P, Varma D, Kurumboor P.

J Gastrointest Surg. 2018 Jun;22(6):1124-1126. doi: 10.1007/s11605-017-3636-2. Epub 2017 Nov 29. No abstract available.


Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities.

Nguyen N, Kumar A, Chacko S, Ouellette RJ, Ghosh A.

Cell Commun Signal. 2017 Nov 14;15(1):48. doi: 10.1186/s12964-017-0204-z.


Oncology practitioners' perspectives and practice patterns of post-treatment cancer survivorship care in the Asia-Pacific region: results from the STEP study.

Chan RJ, Yates P, Li Q, Komatsu H, Lopez V, Thandar M, Chacko ST, So WKW, Pongthavornkamol K, Yi M, Pittayapan P, Butcon J, Wyld D, Molassiotis A; STEP study collaborators.

BMC Cancer. 2017 Nov 6;17(1):715. doi: 10.1186/s12885-017-3733-3. Erratum in: BMC Cancer. 2018 Mar 1;18(1):240.


Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity.

Shi X, Chacko S, Li F, Li D, Burrin D, Chan L, Guan X.

Mol Metab. 2017 Nov;6(11):1350-1359. doi: 10.1016/j.molmet.2017.08.009. Epub 2017 Sep 1.


Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).

Pinto DJP, Orwat MJ, Smith LM 2nd, Quan ML, Lam PYS, Rossi KA, Apedo A, Bozarth JM, Wu Y, Zheng JJ, Xin B, Toussaint N, Stetsko P, Gudmundsson O, Maxwell B, Crain EJ, Wong PC, Lou Z, Harper TW, Chacko SA, Myers JE Jr, Sheriff S, Zhang H, Hou X, Mathur A, Seiffert DA, Wexler RR, Luettgen JM, Ewing WR.

J Med Chem. 2017 Dec 14;60(23):9703-9723. doi: 10.1021/acs.jmedchem.7b01171. Epub 2017 Nov 17.


hace1 Influences zebrafish cardiac development via ROS-dependent mechanisms.

Razaghi B, Steele SL, Prykhozhij SV, Stoyek MR, Hill JA, Cooper MD, McDonald L, Lin W, Daugaard M, Crapoulet N, Chacko S, Lewis SM, Scott IC, Sorensen PHB, Berman JN.

Dev Dyn. 2018 Feb;247(2):289-303. doi: 10.1002/dvdy.24600. Epub 2017 Oct 27.


Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis.

Gorla SK, Zhang Y, Rabideau MM, Qin A, Chacko S, House AL, Johnson CR, Mandapati K, Bernstein HM, McKenney ES, Boshoff H, Zhang M, Glomski IJ, Goldberg JB, Cuny GD, Mann BJ, Hedstrom L.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00939-17. doi: 10.1128/AAC.00939-17. Print 2017 Oct.


Progress Toward Measles Elimination - Bangladesh, 2000-2016.

Khanal S, Bohara R, Chacko S, Sharifuzzaman M, Shamsuzzaman M, Goodson JL, Dabbagh A, Kretsinger K, Dhongde D, Liyanage J, Bahl S, Thapa A.

MMWR Morb Mortal Wkly Rep. 2017 Jul 21;66(28):753-757. doi: 10.15585/mmwr.mm6628a3.

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