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Differential time to positivity of central and peripheral blood cultures is inaccurate for the diagnosis of Staphylococcus aureus long-term catheter-related sepsis.

Bouzidi H, Emirian A, Marty A, Chachaty E, Laplanche A, Gachot B, Blot F.

J Hosp Infect. 2018 Jun;99(2):192-199. doi: 10.1016/j.jhin.2018.01.010. Epub 2018 Feb 10.


Protection of the Human Gut Microbiome From Antibiotics.

de Gunzburg J, Ghozlane A, Ducher A, Le Chatelier E, Duval X, Ruppé E, Armand-Lefevre L, Sablier-Gallis F, Burdet C, Alavoine L, Chachaty E, Augustin V, Varastet M, Levenez F, Kennedy S, Pons N, Mentré F, Andremont A.

J Infect Dis. 2018 Jan 30;217(4):628-636. doi: 10.1093/infdis/jix604.


A Long-Term Study of the Diversity of OXA-48-Like Carbapenemase-Producing Bacterial Strains in Infected Patients and Carriers.

Woerther PL, Jardak T, Ben Hassine I, Forget S, Chachaty E, Arlet G, Decré D.

Microb Drug Resist. 2018 Mar;24(2):181-189. doi: 10.1089/mdr.2017.0060. Epub 2017 Jul 14.


Eggerthella lenta bacteremia in solid tumor cancer patients: Pathogen or witness of frailty?

Woerther PL, Antoun S, Chachaty E, Merad M.

Anaerobe. 2017 Oct;47:70-72. doi: 10.1016/j.anaerobe.2017.04.010. Epub 2017 Apr 22.


Invasive cutaneous infection due to Scopulariopsis brevicaulis unsuccessfully treated with high-dose micafungin in a neutropenic patient.

Gavril D, Woerther PL, Ben Lakhdar A, Mahjoubi L, Routier E, Chachaty E, Gachot B, De Botton S, Micol JB, Willekens C.

Infection. 2017 Jun;45(3):361-363. doi: 10.1007/s15010-016-0971-2. Epub 2016 Dec 1.


Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.

Daillère R, Vétizou M, Waldschmitt N, Yamazaki T, Isnard C, Poirier-Colame V, Duong CPM, Flament C, Lepage P, Roberti MP, Routy B, Jacquelot N, Apetoh L, Becharef S, Rusakiewicz S, Langella P, Sokol H, Kroemer G, Enot D, Roux A, Eggermont A, Tartour E, Johannes L, Woerther PL, Chachaty E, Soria JC, Golden E, Formenti S, Plebanski M, Madondo M, Rosenstiel P, Raoult D, Cattoir V, Boneca IG, Chamaillard M, Zitvogel L.

Immunity. 2016 Oct 18;45(4):931-943. doi: 10.1016/j.immuni.2016.09.009. Epub 2016 Oct 4.


Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.

Vétizou M, Pitt JM, Daillère R, Lepage P, Waldschmitt N, Flament C, Rusakiewicz S, Routy B, Roberti MP, Duong CP, Poirier-Colame V, Roux A, Becharef S, Formenti S, Golden E, Cording S, Eberl G, Schlitzer A, Ginhoux F, Mani S, Yamazaki T, Jacquelot N, Enot DP, Bérard M, Nigou J, Opolon P, Eggermont A, Woerther PL, Chachaty E, Chaput N, Robert C, Mateus C, Kroemer G, Raoult D, Boneca IG, Carbonnel F, Chamaillard M, Zitvogel L.

Science. 2015 Nov 27;350(6264):1079-84. doi: 10.1126/science.aad1329. Epub 2015 Nov 5.


Monitoring antibiotic-resistant enterobacteria faecal levels is helpful in predicting antibiotic susceptibility of bacteraemia isolates in patients with haematological malignancies.

Woerther PL, Micol JB, Angebault C, Pasquier F, Pilorge S, Bourhis JH, de Botton S, Gachot B, Chachaty E.

J Med Microbiol. 2015 Jul;64(7):676-81. doi: 10.1099/jmm.0.000078. Epub 2015 May 1.


[Modalities of management of cancer patients with febrile neutropenia in the oncology emergency unit of Gustave-Roussy and their related costs].

Borget I, Antoun S, Chachaty E, Gachot B, Alibay A, Di Palma M, Merad M.

Bull Cancer. 2014 Oct;101(10):925-31. doi: 10.1684/bdc.2014.1958. French.


Mathematical modeling of bacterial kinetics to predict the impact of antibiotic colonic exposure and treatment duration on the amount of resistant enterobacteria excreted.

Nguyen TT, Guedj J, Chachaty E, de Gunzburg J, Andremont A, Mentré F.

PLoS Comput Biol. 2014 Sep 11;10(9):e1003840. doi: 10.1371/journal.pcbi.1003840. eCollection 2014 Sep.


Factors influencing posaconazole plasmatic concentrations in patients presenting with acute myeloid leukemia.

Desplanques PY, Burlacu R, Poinsignon V, Boussion H, Borget I, Wyplosz B, de Botton S, Billaud E, Chachaty E, Gachot B, Netzer F, Micol JB.

Med Mal Infect. 2014 Apr;44(4):174-9. doi: 10.1016/j.medmal.2014.02.005. Epub 2014 Mar 19.


Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.

Janin M, Mylonas E, Saada V, Micol JB, Renneville A, Quivoron C, Koscielny S, Scourzic L, Forget S, Pautas C, Caillot D, Preudhomme C, Dombret H, Berthon C, Barouki R, Rabier D, Auger N, Griscelli F, Chachaty E, Leclercq E, Courtier MH, Bennaceur-Griscelli A, Solary E, Bernard OA, Penard-Lacronique V, Ottolenghi C, de Botton S.

J Clin Oncol. 2014 Feb 1;32(4):297-305. doi: 10.1200/JCO.2013.50.2047. Epub 2013 Dec 16.


Discontinuation of empirical antibiotic therapy in neutropenic acute myeloid leukaemia patients with fever of unknown origin: is it ethical?

Micol JB, Chahine C, Woerther PL, Ghez D, Netzer F, Dufour C, Merad M, Blot F, Chachaty E, de Botton S, Gachot B.

Clin Microbiol Infect. 2014 Jul;20(7):O453-5. doi: 10.1111/1469-0691.12445. Epub 2013 Dec 9.


The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide.

Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L.

Science. 2013 Nov 22;342(6161):971-6. doi: 10.1126/science.1240537.


Trends in human fecal carriage of extended-spectrum β-lactamases in the community: toward the globalization of CTX-M.

Woerther PL, Burdet C, Chachaty E, Andremont A.

Clin Microbiol Rev. 2013 Oct;26(4):744-58. doi: 10.1128/CMR.00023-13. Review.


Oral DAV131, a charcoal-based adsorbent, inhibits intestinal colonization by β-lactam-resistant Klebsiella pneumoniae in cefotaxime-treated mice.

Grall N, Massias L, Nguyen TT, Sayah-Jeanne S, Ducrot N, Chachaty E, de Gunzburg J, Andremont A.

Antimicrob Agents Chemother. 2013 Nov;57(11):5423-5. doi: 10.1128/AAC.00039-13. Epub 2013 Aug 19.


Intravascular catheter-related bloodstream infection caused by Abiotrophia defectiva in a neutropenic child.

Phulpin-Weibel A, Gaspar N, Emirian A, Chachaty E, Valteau-Couanet D, Gachot B.

J Med Microbiol. 2013 May;62(Pt 5):789-91. doi: 10.1099/jmm.0.047191-0. Epub 2013 Feb 1.


Correlation between fecal concentrations of ciprofloxacin and fecal counts of resistant Enterobacteriaceae in piglets treated with ciprofloxacin: toward new means to control the spread of resistance?

Nguyen TT, Chachaty E, Huy C, Cambier C, de Gunzburg J, Mentré F, Andremont A.

Antimicrob Agents Chemother. 2012 Sep;56(9):4973-5. doi: 10.1128/AAC.06402-11. Epub 2012 Jul 2.


International retrospective analysis of 73 cases of invasive fusariosis treated with voriconazole.

Lortholary O, Obenga G, Biswas P, Caillot D, Chachaty E, Bienvenu AL, Cornet M, Greene J, Herbrecht R, Lacroix C, Grenouillet F, Raad I, Sitbon K, Troke P; French Mycoses Study Group.

Antimicrob Agents Chemother. 2010 Oct;54(10):4446-50. doi: 10.1128/AAC.00286-10. Epub 2010 Jul 12.


Microbiological and physicochemical stability of oxycodone hydrochloride solutions for patient-controlled delivery systems.

Amri A, Ben Achour A, Chachaty E, Mercier L, Bourget P, Paci A.

J Pain Symptom Manage. 2010 Jul;40(1):87-94. doi: 10.1016/j.jpainsymman.2009.11.323. Epub 2010 Jun 8.


Genetic context of plasmid-carried blaCMY-2-like genes in Enterobacteriaceae.

Verdet C, Gautier V, Chachaty E, Ronco E, Hidri N, Decré D, Arlet G.

Antimicrob Agents Chemother. 2009 Sep;53(9):4002-6. doi: 10.1128/AAC.00753-08. Epub 2009 Jul 13.


[Two cases of Bacillus infection and immunodepression].

Farhat H, Chachaty E, Antoun S, Nitenberg G, Zahar JR.

Med Mal Infect. 2008 Nov;38(11):612-4. doi: 10.1016/j.medmal.2008.09.006. Epub 2008 Oct 30. French.


Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France.

Desnos-Ollivier M, Bretagne S, Bernède C, Robert V, Raoux D, Chachaty E, Forget E, Lacroix C, Dromer F; Yeasts Group.

Emerg Infect Dis. 2008 Apr;14(4):557-65. doi: 10.3201/eid1404.071083.


Is routine changing of peripheral arterial catheters justified?

Blot F, Estphan G, Boughaba A, Soltani D, Edé C, Chachaty E.

Clin Microbiol Infect. 2008 Sep;14(9):813-5. doi: 10.1111/j.1469-0691.2008.02001.x. Epub 2008 Apr 3.


Intercontinental travels of patients and dissemination of plasmid-mediated carbapenemase KPC-3 associated with OXA-9 and TEM-1.

Dortet L, Radu I, Gautier V, Blot F, Chachaty E, Arlet G.

J Antimicrob Chemother. 2008 Feb;61(2):455-7. Epub 2007 Nov 20. No abstract available.


Microbiological and physicochemical stability of fentanyl and sufentanil solutions for patient-controlled delivery systems.

Chapalain-Pargade S, Laville I, Paci A, Chachaty E, Mercier L, Bourget P.

J Pain Symptom Manage. 2006 Jul;32(1):90-7.


Incidence and clinical significance of anaerobic bacteraemia in cancer patients: a 6-year retrospective study.

Zahar JR, Farhat H, Chachaty E, Meshaka P, Antoun S, Nitenberg G.

Clin Microbiol Infect. 2005 Sep;11(9):724-9.


[Shelf-lives of morphine and pethidine solutions stored in patient-controlled analgesia devices: physico-chemical and microbiological stability study].

Laville I, Mercier L, Chachaty E, Bourget P, Paci A.

Pathol Biol (Paris). 2005 May;53(4):210-6. French.


Indwelling time and risk of infection of dialysis catheters in critically ill cancer patients.

Harb A, Estphan G, Nitenberg G, Chachaty E, Raynard B, Blot F.

Intensive Care Med. 2005 Jun;31(6):812-7. Epub 2005 Apr 16.


[Epidemiology and antimicrobial resistance of Streptococcus pneumoniae strains isolated in Ile de France area during 2001].

Demachy MC, Faibis F, Artigou A, Benoit C, Cambau E, Cecille A, Chachaty E, Chaplain C, Cormier P, Cousinard F, Decotte JC, Demontrond D, Dublanchet A, Dupeyron C, Farges A, Ferre B, Fremaux AP, Galanti MJ, Gallet C, Guiet P, Hacquard B, Hornstein M, Legrand P, Le Manach F, Lucet N, Malbrunot C, Mangeol A, Mathieu D, Otterbein G, Pateyron F, Poilane I, Pollet J, Rabenja T, Spicq C.

Med Mal Infect. 2004 Jul;34(7):303-9. French.


[Usefulness of panfungal PCR for the diagnosis of fungal infection in immunocompromised patients].

Adam O, Merad M, Antoun S, Bourhis JH, Gachot B, Casiraghi O, Chachaty E.

Pathol Biol (Paris). 2004 Nov;52(9):544-9. French.


Treatment with piperacillin-tazobactam and false-positive Aspergillus galactomannan antigen test results for patients with hematological malignancies.

Adam O, Aupérin A, Wilquin F, Bourhis JH, Gachot B, Chachaty E.

Clin Infect Dis. 2004 Mar 15;38(6):917-20. Epub 2004 Feb 27.


Candida infections in children treated with conventional chemotherapy for solid tumors (transplant recipients excluded): The Institut Gustave Roussy Pediatrics Department experience.

Ridola V, Chachaty E, Raimondo G, Corradini N, Brugieres L, Valteau-Couanet D, Hartmann O.

Pediatr Blood Cancer. 2004 Apr;42(4):332-7.


Isospora belli infection in a patient with non-Hodgkin's lymphoma.

Resiere D, Vantelon JM, Bourée P, Chachaty E, Nitenberg G, Blot F.

Clin Microbiol Infect. 2003 Oct;9(10):1065-7.


[Mycologic surveillance of the environment for preventive invasive aspergillosis. Proposals for standardization of the methodologies and implementation].

Gangneux JP, Poirot JL, Morin O, Derouin F, Bretagne S, Datry A, Kauffmann-Lacroix C, Paugam A, Chandenier J, Bouakline A, Bordes M, Chachaty E, Dupeyron C, Grawey I, Lecso G, Lortholary J, Mourlhou P, Nesa D, Saheb F, Cornet M, Vimont AM, Cordonnier C.

Presse Med. 2002 May 25;31(18):841-8. French.


Surveillance of Aspergillus galactomannan antigenemia for invasive aspergillosis by enzyme-linked immunosorbent assay in neutropenic patients treated for hematological malignancies.

Ulusakarya A, Chachaty E, Vantelon JM, Youssef A, Tancrède C, Pico JL, Bourhis JH, Fenaux P, Munck JN.

Hematol J. 2000;1(2):111-6.


Use of molecular typing to investigate bacterial translocation from the intestinal tract in malnourished children with Gram-negative bacteremia.

Youssef M, Al Shurman A, Chachaty E, Bsoul AR, Andremont A.

Clin Microbiol Infect. 1998 Feb;4(2):70-74.


Impact of quinupristin/dalfopristin (RP59500) on the faecal microflora in healthy volunteers.

Scanvic-Hameg A, Chachaty E, Rey J, Pousson C, Ozoux ML, Brunel E, Andremont A.

J Antimicrob Chemother. 2002 Jan;49(1):135-9.


Mechanisms and risk factors for infection of pulmonary artery catheters and introducer sheaths in cancer patients admitted to an intensive care unit.

Blot F, Chachaty E, Raynard B, Antoun S, Bourgain JL, Nitenberg G.

J Hosp Infect. 2001 Aug;48(4):289-97.


Value of gram stain examination of lower respiratory tract secretions for early diagnosis of nosocomial pneumonia.

Blot F, Raynard B, Chachaty E, Tancrède C, Antoun S, Nitenberg G.

Am J Respir Crit Care Med. 2000 Nov;162(5):1731-7.


Intranasal immunization with protein-linked phosphorylcholine protects mice against a lethal intranasal challenge with streptococcus pneumoniae.

Trolle S, Chachaty E, Kassis-Chikhani N, Wang C, Fattal E, Couvreur P, Diamond B, Alonso J, Andremont A.

Vaccine. 2000 Jul 1;18(26):2991-8.


Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures.

Blot F, Nitenberg G, Chachaty E, Raynard B, Germann N, Antoun S, Laplanche A, Brun-Buisson C, Tancrède C.

Lancet. 1999 Sep 25;354(9184):1071-7.


Drug targeting by polyalkylcyanoacrylate nanoparticles is not efficient against persistent Salmonella.

Page-Clisson ME, Pinto-Alphandary H, Chachaty E, Couvreur P, Andremont A.

Pharm Res. 1998 Apr;15(4):544-9.


Mucosal immunogenicity elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly (D,L-lactide-co-glycolide) microspheres.

Allaoui-Attarki K, Fattal E, Pecquet S, Trollé S, Chachaty E, Couvreur P, Andremont A.

Vaccine. 1998 Apr;16(7):685-91.


Decontamination of polymerase chain reaction reagents for detection of low concentrations of 16S rRNA genes.

Hilali F, Saulnier P, Chachaty E, Andremont A.

Mol Biotechnol. 1997 Jun;7(3):207-16.


Single-step polymerase chain reaction for combined gene detection and epidemiological typing in three bacterial models.

Saulnier P, Chachaty E, Hilali F, Andremont A.

FEMS Microbiol Lett. 1997 May 15;150(2):311-6.


Protective immunity against Salmonella typhimurium elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly(DL-lactide-co-glycolide) microspheres.

Allaoui-Attarki K, Pecquet S, Fattal E, Trollé S, Chachaty E, Couvreur P, Andremont A.

Infect Immun. 1997 Mar;65(3):853-7.


Surveillance of intestinal colonization and of infection by vancomycin-resistant enterococci in hospitalized cancer patients.

Moulin F, Dumontier S, Saulnier P, Chachaty E, Loubeyre C, Brugières L, Andremont A.

Clin Microbiol Infect. 1996 Feb;2(3):192-201.


Shedding of antibiotic-resistant members of the family Enterobacteriaceae in healthy residents of France and Jordan.

Chachaty E, Youssef MT, Bourneix C, Andremont A.

Res Microbiol. 1995 Feb;146(2):175-82.


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