Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20


Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen.

Chachami G, Stankovic-Valentin N, Karagiota A, Basagianni A, Plessmann U, Urlaub H, Melchior F, Simos G.

Mol Cell Proteomics. 2019 Jun;18(6):1197-1209. doi: 10.1074/mcp.RA119.001401. Epub 2019 Mar 29.


Protein phosphatase PPP3CA (calcineurin A) down-regulates hypoxia-inducible factor transcriptional activity.

Karagiota A, Mylonis I, Simos G, Chachami G.

Arch Biochem Biophys. 2019 Mar 30;664:174-182. doi: 10.1016/ Epub 2019 Feb 15.


Low Serum Hepcidin in Patients with Autoimmune Liver Diseases.

Lyberopoulou A, Chachami G, Gatselis NK, Kyratzopoulou E, Saitis A, Gabeta S, Eliades P, Paraskeva E, Zachou K, Koukoulis GK, Mamalaki A, Dalekos GN, Simos G.

PLoS One. 2015 Aug 13;10(8):e0135486. doi: 10.1371/journal.pone.0135486. eCollection 2015.


A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

Hutten S, Chachami G, Winter U, Melchior F, Lamond AI.

J Cell Sci. 2014 Mar 1;127(Pt 5):1065-78. doi: 10.1242/jcs.141788. Epub 2014 Jan 10.


An association study between hypoxia inducible factor-1alpha (HIF-1α) polymorphisms and osteonecrosis.

Chachami G, Kalousi A, Papatheodorou L, Lyberopoulou A, Nasikas V, Tanimoto K, Simos G, Malizos KN, Georgatsou E.

PLoS One. 2013 Nov 18;8(11):e79647. doi: 10.1371/journal.pone.0079647. eCollection 2013.


Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera.

Chachami G, Lyberopoulou A, Kalousi A, Paraskeva E, Pantopoulos K, Simos G.

Biochem Biophys Res Commun. 2013 Jun 14;435(4):540-5. doi: 10.1016/j.bbrc.2013.04.085. Epub 2013 May 8.


Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions.

Schulz S, Chachami G, Kozaczkiewicz L, Winter U, Stankovic-Valentin N, Haas P, Hofmann K, Urlaub H, Ovaa H, Wittbrodt J, Meulmeester E, Melchior F.

EMBO Rep. 2012 Oct;13(10):930-8. doi: 10.1038/embor.2012.125. Epub 2012 Aug 10.


Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect.

Darekar S, Georgiou K, Yurchenko M, Yenamandra SP, Chachami G, Simos G, Klein G, Kashuba E.

PLoS One. 2012;7(7):e42072. doi: 10.1371/journal.pone.0042072. Epub 2012 Jul 27.


Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

Kalousi A, Mylonis I, Politou AS, Chachami G, Paraskeva E, Simos G.

J Cell Sci. 2010 Sep 1;123(Pt 17):2976-86. doi: 10.1242/jcs.068122. Epub 2010 Aug 10.


Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.

Chachami G, Paraskeva E, Mingot JM, Braliou GG, Görlich D, Simos G.

Biochem Biophys Res Commun. 2009 Dec 11;390(2):235-40. doi: 10.1016/j.bbrc.2009.09.093. Epub 2009 Sep 27.


Inhaled insulin does not trigger lung inflammation and airway remodelling.

Papagianni M, Hatziefthimiou A, Chachami G, Gourgoulianis K, Molyvdas PA, Paraskeva E.

Eur Respir J. 2009 Feb;33(2):444-5. doi: 10.1183/09031936.00140708. No abstract available.


Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1alpha by MAPK.

Mylonis I, Chachami G, Paraskeva E, Simos G.

J Biol Chem. 2008 Oct 10;283(41):27620-7. doi: 10.1074/jbc.M803081200. Epub 2008 Aug 7.


2-Oxoglutarate-dependent oxygenases control hepcidin gene expression.

Braliou GG, Verga Falzacappa MV, Chachami G, Casanovas G, Muckenthaler MU, Simos G.

J Hepatol. 2008 May;48(5):801-10. doi: 10.1016/j.jhep.2007.12.021. Epub 2008 Feb 13.


MgcRacGAP interacts with HIF-1alpha and regulates its transcriptional activity.

Lyberopoulou A, Venieris E, Mylonis I, Chachami G, Pappas I, Simos G, Bonanou S, Georgatsou E.

Cell Physiol Biochem. 2007;20(6):995-1006.


Exposure of differentiated airway smooth muscle cells to serum stimulates both induction of hypoxia-inducible factor-1{alpha} and airway responsiveness to ACh.

Chachami G, Hatziefthimiou A, Liakos P, Ioannou MG, Koukoulis GK, Bonanou S, Molyvdas PA, Simos G, Paraskeva E.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L913-22. Epub 2007 Jul 27.


The flavonoid quercetin induces hypoxia-inducible factor-1alpha (HIF-1alpha) and inhibits cell proliferation by depleting intracellular iron.

Triantafyllou A, Liakos P, Tsakalof A, Chachami G, Paraskeva E, Molyvdas PA, Georgatsou E, Simos G, Bonanou S.

Free Radic Res. 2007 Mar;41(3):342-56.


Insulin causes a transient induction of proliferation via activation of the PI3-kinase pathway in airway smooth muscle cells.

Papagianni M, Hatziefthimiou A, Chachami G, Gourgoulianis K, Molyvdas PA, Paraskeva E.

Exp Clin Endocrinol Diabetes. 2007 Feb;115(2):118-23.


Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha.

Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, Georgatsou E, Bonanou S, Simos G.

J Biol Chem. 2006 Nov 3;281(44):33095-106. Epub 2006 Sep 5.


Bacterially produced human HIF-1alpha is competent for heterodimerization and specific DNA-binding.

Chachami G, Paraskeva E, Georgatsou E, Bonanou S, Simos G.

Biochem Biophys Res Commun. 2005 Jun 3;331(2):464-70.


Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.

Chachami G, Simos G, Hatziefthimiou A, Bonanou S, Molyvdas PA, Paraskeva E.

Am J Respir Cell Mol Biol. 2004 Nov;31(5):544-51. Epub 2004 Jul 15.


Supplemental Content

Loading ...
Support Center