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Items: 1 to 50 of 89

1.

Impact of l-carnitine supplementation on metabolic profiles in premature infants.

Clark RH, Chace DH, Spitzer AR.

J Perinatol. 2017 May;37(5):566-571. doi: 10.1038/jp.2016.253. Epub 2017 Jan 12.

PMID:
28079870
2.

Filter Paper as a Blood Sample Collection Device for Newborn Screening.

Chace DH, Hannon WH.

Clin Chem. 2016 Mar;62(3):423-5. doi: 10.1373/clinchem.2015.252007. Epub 2016 Jan 21. No abstract available.

3.

Heptadecanoylcarnitine (C17) a novel candidate biomarker for newborn screening of propionic and methylmalonic acidemias.

Malvagia S, Haynes CA, Grisotto L, Ombrone D, Funghini S, Moretti E, McGreevy KS, Biggeri A, Guerrini R, Yahyaoui R, Garg U, Seeterlin M, Chace D, De Jesus VR, la Marca G.

Clin Chim Acta. 2015 Oct 23;450:342-8. doi: 10.1016/j.cca.2015.09.012. Epub 2015 Sep 11.

4.

Clinical chemistry and dried blood spots: increasing laboratory utilization by improved understanding of quantitative challenges.

Chace DH, De Jesús VR, Spitzer AR.

Bioanalysis. 2014;6(21):2791-4. doi: 10.4155/bio.14.237. No abstract available.

5.

Gestational age and age at sampling influence metabolic profiles in premature infants.

Clark RH, Kelleher AS, Chace DH, Spitzer AR.

Pediatrics. 2014 Jul;134(1):e37-46. doi: 10.1542/peds.2014-0329. Epub 2014 Jun 9.

PMID:
24913786
6.

Microsample analyses via DBS: challenges and opportunities.

Henion J, Oliveira RV, Chace DH.

Bioanalysis. 2013 Oct;5(20):2547-65. doi: 10.4155/bio.13.197. Review.

PMID:
24138627
7.

Elaidate, an 18-carbon trans-monoenoic fatty acid, inhibits β-oxidation in human peripheral blood macrophages.

Zacherl JR, Mihalik SJ, Chace DH, Christensen TC, Robinson LJ, Blair HC.

J Cell Biochem. 2014 Jan;115(1):62-70. doi: 10.1002/jcb.24633.

PMID:
23904193
8.

Metabolomic profiling of amino acids and β-cell function relative to insulin sensitivity in youth.

Michaliszyn SF, Sjaarda LA, Mihalik SJ, Lee S, Bacha F, Chace DH, De Jesus VR, Vockley J, Arslanian SA.

J Clin Endocrinol Metab. 2012 Nov;97(11):E2119-24. doi: 10.1210/jc.2012-2170. Epub 2012 Sep 13.

9.

Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis.

Weiss SL, Haymond S, Ralay Ranaivo H, Wang D, De Jesus VR, Chace DH, Wainwright MS.

Pediatr Crit Care Med. 2012 Jul;13(4):e210-8. doi: 10.1097/PCC.0b013e318238b5cd.

10.

Commentary on the history and quantitative nature of filter paper used in blood collection devices.

De Jesús VR, Chace DH.

Bioanalysis. 2012 Mar;4(6):645-7. doi: 10.4155/bio.12.34. No abstract available.

11.

Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation.

Mihalik SJ, Michaliszyn SF, de las Heras J, Bacha F, Lee S, Chace DH, DeJesus VR, Vockley J, Arslanian SA.

Diabetes Care. 2012 Mar;35(3):605-11. doi: 10.2337/DC11-1577. Epub 2012 Jan 20.

12.

Detection of TPN contamination of dried blood spots used in newborn and metabolic screening and its impact on quantitative measurement of amino acids.

Chace DH, De Jesús VR, Lim TH, Hannon WH, Clark RH, Spitzer AR.

Clin Chim Acta. 2011 Jul 15;412(15-16):1385-90. doi: 10.1016/j.cca.2011.04.009. Epub 2011 Apr 14.

PMID:
21514290
13.

Altered metabolism and newborn screening using tandem mass spectrometry: lessons learned from the bench to bedside.

Chace DH, Spitzer AR.

Curr Pharm Biotechnol. 2011 Jul;12(7):965-75. Review.

PMID:
21466463
14.

Proficiency testing outcomes of 3-hydroxyisovalerylcarnitine measurements by tandem mass spectrometry in newborn screening.

Lim TH, De Jesús VR, Meredith NK, Sternberg MR, Chace DH, Mei JV, Hannon WH.

Clin Chim Acta. 2011 Mar 18;412(7-8):631-5. doi: 10.1016/j.cca.2010.12.021. Epub 2010 Dec 23.

PMID:
21185274
15.

Impact of second-tier testing on the effectiveness of newborn screening.

Chace DH, Hannon WH.

Clin Chem. 2010 Nov;56(11):1653-5. doi: 10.1373/clinchem.2010.153494. Epub 2010 Sep 13. No abstract available.

16.

Tandem mass spectrometric identification of dextrose markers in dried-blood spots from infants receiving total parenteral nutrition.

Chace DH, De Jesús VR, Lim TH, Hannon WH, Spitzer AR.

Clin Chim Acta. 2010 Nov 11;411(21-22):1806-16. doi: 10.1016/j.cca.2010.08.007. Epub 2010 Aug 11.

PMID:
20707991
17.

Potential loss of methionine following extended storage of newborn screening samples prepared for tandem mass spectrometry analysis.

Chace DH, Luo Z, De Jesús VR, Haynes CA, Hannon WH.

Clin Chim Acta. 2010 Sep 6;411(17-18):1284-6. doi: 10.1016/j.cca.2010.05.011. Epub 2010 May 15.

PMID:
20478282
18.

Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry.

De Jesús VR, Chace DH, Lim TH, Mei JV, Hannon WH.

Clin Chim Acta. 2010 May 2;411(9-10):684-9. doi: 10.1016/j.cca.2010.01.034. Epub 2010 Feb 1.

PMID:
20122909
19.

Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity.

Mihalik SJ, Goodpaster BH, Kelley DE, Chace DH, Vockley J, Toledo FG, DeLany JP.

Obesity (Silver Spring). 2010 Sep;18(9):1695-700. doi: 10.1038/oby.2009.510. Epub 2010 Jan 28.

20.

Improved MS/MS analysis of succinylacetone extracted from dried blood spots when combined with amino acids and acylcarnitine butyl esters.

Chace DH, Lim T, Hansen CR, De Jesus VR, Hannon WH.

Clin Chim Acta. 2009 Sep;407(1-2):6-9. doi: 10.1016/j.cca.2009.06.017. Epub 2009 Jun 21.

PMID:
19545553
21.

Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease.

Skvorak KJ, Paul HS, Dorko K, Marongiu F, Ellis E, Chace D, Ferguson C, Gibson KM, Homanics GE, Strom SC.

Mol Ther. 2009 Jul;17(7):1266-73. doi: 10.1038/mt.2009.99. Epub 2009 May 12.

22.

Rapid metabolic and newborn screening of thyroxine (T4) from dried blood spots by MS/MS.

Chace DH, Singleton S, Diperna J, Aiello M, Foley T.

Clin Chim Acta. 2009 May;403(1-2):178-83. doi: 10.1016/j.cca.2009.02.012. Epub 2009 Feb 28.

PMID:
19254705
23.

Quantification of malonylcarnitine in dried blood spots by use of MS/MS varies by stable isotope internal standard composition.

Chace DH, Lim T, Hansen CR, Adam BW, Hannon WH.

Clin Chim Acta. 2009 Apr;402(1-2):14-8. doi: 10.1016/j.cca.2008.10.035. Epub 2008 Nov 13.

PMID:
19041298
24.

Mass spectrometry in newborn and metabolic screening: historical perspective and future directions.

Chace DH.

J Mass Spectrom. 2009 Feb;44(2):163-70. doi: 10.1002/jms.1528.

PMID:
19034889
25.

Proteomics- and metabolomics-based neonatal diagnostics in assessing and managing the critically ill neonate.

Spitzer AR, Chace D.

Clin Perinatol. 2008 Dec;35(4):695-716, vi. doi: 10.1016/j.clp.2008.07.019. Review.

PMID:
19026335
26.

Determination of the reference range of endogenous plasma carnitines in healthy adults.

Reuter SE, Evans AM, Chace DH, Fornasini G.

Ann Clin Biochem. 2008 Nov;45(Pt 6):585-92. doi: 10.1258/acb.2008.008045. Epub 2008 Sep 9.

PMID:
18782814
27.

The influence of amino-acid supplementation, gestational age and time on thyroxine levels in premature neonates.

Kelleher AS, Clark RH, Steinbach M, Chace DH, Spitzer AR; Pediatrix Amino-Acid Study Group.

J Perinatol. 2008 Apr;28(4):270-4. doi: 10.1038/jp.2008.5. Epub 2008 Feb 21.

PMID:
18288119
28.

Demographic and nutritional factors associated with prolonged cholestatic jaundice in the premature infant.

Steinbach M, Clark RH, Kelleher AS, Flores C, White R, Chace DH, Spitzer AR; Pediatrix Amino-Acid Study Group.

J Perinatol. 2008 Feb;28(2):129-35. Epub 2007 Dec 6.

PMID:
18059467
30.

Mass spectrometry in neonatal medicine and clinical diagnosis--the [corrected] potential use of mass spectrometry in neonatal brain [corrected] monitoring.

Spitzer AR, Chace D.

Clin Perinatol. 2006 Sep;33(3):729-44, viii. Erratum in: Clin Perinatol. 2007 Mar;34(1):xiii.

PMID:
16950322
31.

Metabolic disorders detectable by tandem mass spectrometry and unexpected early childhood mortality: a population-based study.

Dott M, Chace D, Fierro M, Kalas TA, Hannon WH, Williams J, Rasmussen SA.

Am J Med Genet A. 2006 Apr 15;140(8):837-42.

PMID:
16528746
32.

2005 International Conference on Metabolic Profiling. November 14-15, 2006, NC, USA.

Chace DH.

Expert Rev Mol Diagn. 2006 Mar;6(2):135-6. No abstract available.

PMID:
16512772
33.

Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.

Wainwright MS, Kohli R, Whitington PF, Chace DH.

Stroke. 2006 Feb;37(2):524-30. Epub 2005 Dec 29.

PMID:
16385097
34.

2005 Biomarker Discovery Summit: impressions and summary. September 26-28, 2005, PA, USA.

Chace DH.

Expert Rev Proteomics. 2005 Dec;2(6):837-8. No abstract available.

PMID:
16307514
35.

Impact of haemodialysis on individual endogenous plasma acylcarnitine concentrations in end-stage renal disease.

Reuter SE, Evans AM, Faull RJ, Chace DH, Fornasini G.

Ann Clin Biochem. 2005 Sep;42(Pt 5):387-93.

PMID:
16168195
36.

Tetrahydrobiopterin and nitric oxide synthase dimer levels are not changed following hypoxia-ischemia in the newborn rat.

Wainwright MS, Arteaga E, Fink R, Ravi K, Chace DH, Black SM.

Brain Res Dev Brain Res. 2005 May 12;156(2):183-92.

PMID:
16099305
37.

Analyzing proteomic expression in a clinical screening environment using mass spectrometry.

Chace DH, Spitzer A.

Expert Rev Proteomics. 2005 Aug;2(4):453-4. No abstract available.

PMID:
16097879
38.
39.

A biochemical perspective on the use of tandem mass spectrometry for newborn screening and clinical testing.

Chace DH, Kalas TA.

Clin Biochem. 2005 Apr;38(4):296-309. Review. Erratum in: Clin Biochem. 2005 May;38(5):495.

PMID:
15766731
40.

Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates.

Law CL, Cerveny CG, Gordon KA, Klussman K, Mixan BJ, Chace DF, Meyer DL, Doronina SO, Siegall CB, Francisco JA, Senter PD, Wahl AF.

Clin Cancer Res. 2004 Dec 1;10(23):7842-51. Erratum in: Clin Cancer Res. 2005 May 15;11(10):3969.

41.

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate.

Hamblett KJ, Senter PD, Chace DF, Sun MM, Lenox J, Cerveny CG, Kissler KM, Bernhardt SX, Kopcha AK, Zabinski RF, Meyer DL, Francisco JA.

Clin Cancer Res. 2004 Oct 15;10(20):7063-70.

42.

Steroid profiling by tandem mass spectrometry improves the positive predictive value of newborn screening for congenital adrenal hyperplasia.

Minutti CZ, Lacey JM, Magera MJ, Hahn SH, McCann M, Schulze A, Cheillan D, Dorche C, Chace DH, Lymp JF, Zimmerman D, Rinaldo P, Matern D.

J Clin Endocrinol Metab. 2004 Aug;89(8):3687-93.

PMID:
15292289
43.

Use of tandem mass spectrometry for multianalyte screening of dried blood specimens from newborns.

Chace DH, Kalas TA, Naylor EW.

Clin Chem. 2003 Nov;49(11):1797-817. Review.

44.

Improved yield and stability of L49-sFv-beta-lactamase, a single-chain antibody fusion protein for anticancer prodrug activation, by protein engineering.

McDonagh CF, Beam KS, Wu GJ, Chen JH, Chace DF, Senter PD, Francisco JA.

Bioconjug Chem. 2003 Sep-Oct;14(5):860-9.

PMID:
13129388
45.

Mass spectrometry-based diagnostics: the upcoming revolution in disease detection has already arrived.

Chace DH.

Clin Chem. 2003 Jul;49(7):1227-8; author reply 1228-9. No abstract available.

46.

Development of potent monoclonal antibody auristatin conjugates for cancer therapy.

Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF, DeBlanc RL, Gearing RP, Bovee TD, Siegall CB, Francisco JA, Wahl AF, Meyer DL, Senter PD.

Nat Biotechnol. 2003 Jul;21(7):778-84. Epub 2003 Jun 1.

PMID:
12778055
47.

cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity.

Francisco JA, Cerveny CG, Meyer DL, Mixan BJ, Klussman K, Chace DF, Rejniak SX, Gordon KA, DeBlanc R, Toki BE, Law CL, Doronina SO, Siegall CB, Senter PD, Wahl AF.

Blood. 2003 Aug 15;102(4):1458-65. Epub 2003 Apr 24.

48.

Neonatal blood carnitine concentrations: normative data by electrospray tandem mass spectometry.

Chace DH, Pons R, Chiriboga CA, McMahon DJ, Tein I, Naylor EW, De Vivo DC.

Pediatr Res. 2003 May;53(5):823-9. Epub 2003 Feb 20.

PMID:
12612202
49.

The application of tandem mass spectrometry to neonatal screening for inherited disorders of intermediary metabolism.

Chace DH, Kalas TA, Naylor EW.

Annu Rev Genomics Hum Genet. 2002;3:17-45. Epub 2002 Apr 15. Review.

PMID:
12142359
50.

The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease.

Wahl AF, Klussman K, Thompson JD, Chen JH, Francisco LV, Risdon G, Chace DF, Siegall CB, Francisco JA.

Cancer Res. 2002 Jul 1;62(13):3736-42.

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