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Items: 11

1.

EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer.

Viswanadhapalli S, Luo Y, Sareddy GR, Santhamma B, Zhou M, Li M, Ma S, Sonavane R, Pratap UP, Altwegg KA, Li X, Chang A, Chávez-Riveros A, Dileep KV, Zhang KYJ, Pan X, Murali R, Bajda M, Raj GV, Brenner AJ, Manthati V, Rao MK, Tekmal RR, Nair HB, Nickisch KJ, Vadlamudi RK.

Mol Cancer Ther. 2019 Aug;18(8):1341-1354. doi: 10.1158/1535-7163.MCT-18-1258. Epub 2019 May 29.

PMID:
31142661
2.

Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance.

Abouelhassan Y, Garrison AT, Yang H, Chávez-Riveros A, Burch GM, Huigens RW 3rd.

J Med Chem. 2019 Apr 18. doi: 10.1021/acs.jmedchem.9b00370. [Epub ahead of print]

PMID:
30951303
3.

Utilizing cell line-derived organoids to evaluate the efficacy of a novel LIFR-inhibitor, EC359 in targeting pancreatic tumor stroma.

Hall BR, Cannon A, Thompson C, Santhamma B, Chavez-Riveros A, Bhatia R, Nair HB, Nickisch K, Batra SK, Kumar S.

Genes Cancer. 2019 Feb;10(1-2):1-10. doi: 10.18632/genesandcancer.184.

4.

Synthesis of diphenylamine macrocycles and their anti-inflammatory effects.

Chávez-Riveros A, Hernández-Vázquez E, Nieto-Camacho A, Ramírez-Apan T, Miranda LD.

Org Biomol Chem. 2019 Feb 6;17(6):1423-1435. doi: 10.1039/c8ob03121e.

PMID:
30672562
5.

A Two-Step Multicomponent Synthetic Approach and Anti-inflammatory Evaluation of N-Substituted 2-Oxopyrazines.

Hernández-Vázquez E, Chávez-Riveros A, Nieto-Camacho A, Miranda LD.

ChemMedChem. 2019 Jan 8;14(1):132-146. doi: 10.1002/cmdc.201800634. Epub 2018 Dec 12.

PMID:
30430749
6.

Cytotoxic Activity and Structure-Activity Relationship of Triazole-Containing Bis(Aryl Ether) Macrocycles.

Hernández-Vázquez E, Chávez-Riveros A, Romo-Pérez A, Ramírez-Apán MT, Chávez-Blanco AD, Morales-Bárcenas R, Dueñas-González A, Miranda LD.

ChemMedChem. 2018 Jun 20;13(12):1193-1209. doi: 10.1002/cmdc.201800075. Epub 2018 May 17.

PMID:
29771004
7.

Synthesis and cytotoxic effect of pregnenolone derivatives with one or two α,β-unsaturated carbonyls and an ester moiety at C-21 or C-3.

Chávez-Riveros A, Cruz Noriega A, Ramírez Apan MT, Miranda LD, Bratoeff E.

Steroids. 2018 Mar;131:37-45. doi: 10.1016/j.steroids.2018.01.004. Epub 2018 Jan 31.

PMID:
29360536
8.

Diversity-oriented synthesis and cytotoxic activity evaluation of biaryl-containing macrocycles.

Pérez-Labrada K, Cruz-Mendoza MA, Chávez-Riveros A, Hernández-Vázquez E, Torroba T, Miranda LD.

Org Biomol Chem. 2017 Mar 21;15(11):2450-2458. doi: 10.1039/c6ob02726a. Epub 2017 Mar 3.

PMID:
28255584
9.

Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5α-Reductase.

Chávez-Riveros A, Bratoeff E, Heuze Y, Soriano J, Moreno I, Sánchez-Márquez A, Cabeza M.

Arch Pharm (Weinheim). 2015 Nov;348(11):808-816. doi: 10.1002/ardp.201500220. Epub 2015 Sep 17.

PMID:
26377677
10.

A new approach towards the synthesis of drospirenone and steroidal spirolactones.

Santhamma B, Acosta K, Chavez-Riveros A, Nickisch K.

Steroids. 2015 Oct;102:60-4. doi: 10.1016/j.steroids.2015.07.008. Epub 2015 Jul 26.

PMID:
26216206
11.

Synthesis and cytotoxic effect on cancer cell lines and macrophages of novel progesterone derivatives having an ester or a carbamate function at C-3 and C-17.

Chávez-Riveros A, Garrido M, Ramírez Apan MT, Zambrano A, Díaz M, Bratoeff E.

Eur J Med Chem. 2014 Jul 23;82:498-505. doi: 10.1016/j.ejmech.2014.06.008. Epub 2014 Jun 6.

PMID:
24937183

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