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Items: 46


Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia.

Liang X, Gupta K, Quintero JR, Cernadas M, Kobzik L, Christou H, Pier GB, Owen CA, Çataltepe S.

FASEB J. 2018 Nov 21:fj201802002R. doi: 10.1096/fj.201802002R. [Epub ahead of print]


Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma.

Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Wenzel S, Dunican E, Fahy JV, Irimia D, Wagner DD, Levy BD; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2018 Aug 3;3(26). pii: eaao4747. doi: 10.1126/sciimmunol.aao4747.


ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program- Investigators.

JCI Insight. 2018 Mar 22;3(6). pii: 120932. doi: 10.1172/jci.insight.120932. [Epub ahead of print] No abstract available.


Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.


ALX receptor ligands define a biochemical endotype for severe asthma.

Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.

JCI Insight. 2017 Jul 20;2(14). pii: 93534. doi: 10.1172/jci.insight.93534. [Epub ahead of print]


Alternative Macrophage Activation Is Increased in Asthma.

Girodet PO, Nguyen D, Mancini JD, Hundal M, Zhou X, Israel E, Cernadas M.

Am J Respir Cell Mol Biol. 2016 Oct;55(4):467-475.


Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function.

Reid B, Girodet PO, Boomer JS, Abdel-Gadir A, Zheng K, Wechsler ME, Bacharier LB, Kunselman SJ, King TS, Israel E, Castro M, Cernadas M, Green JM.

J Allergy Clin Immunol. 2016 Jul;138(1):286-289.e9. doi: 10.1016/j.jaci.2015.11.030. Epub 2016 Feb 10. No abstract available.


Circadian rhythm reprogramming during lung inflammation.

Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J, Pelton A, Coronata A, Fredenburgh LE, Choi AM.

Nat Commun. 2014 Sep 11;5:4753. doi: 10.1038/ncomms5753.


Histology of the regeneration of Paulownia tomentosa (Paulowniaceae) by organogenesis.

San José Mdel C, Cernadas MJ, Corredoira E.

Rev Biol Trop. 2014 Jun;62(2):809-18.


Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.

Lai PS, Hofmann O, Baron RM, Cernadas M, Meng QR, Bresler HS, Brass DM, Yang IV, Schwartz DA, Christiani DC, Hide W.

PLoS One. 2013 May 13;8(5):e62910. doi: 10.1371/journal.pone.0062910. Print 2013.


Adam8 limits the development of allergic airway inflammation in mice.

Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA.

J Immunol. 2013 Jun 15;190(12):6434-49. doi: 10.4049/jimmunol.1202329. Epub 2013 May 13.


Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma.

Barnig C, Cernadas M, Dutile S, Liu X, Perrella MA, Kazani S, Wechsler ME, Israel E, Levy BD.

Sci Transl Med. 2013 Feb 27;5(174):174ra26. doi: 10.1126/scitranslmed.3004812.


Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway.

Elmasri H, Ghelfi E, Yu CW, Traphagen S, Cernadas M, Cao H, Shi GP, Plutzky J, Sahin M, Hotamisligil G, Cataltepe S.

Angiogenesis. 2012 Sep;15(3):457-68. doi: 10.1007/s10456-012-9274-0. Epub 2012 May 5.


Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion.

Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM.

Am J Respir Cell Mol Biol. 2012 Aug;47(2):209-17. doi: 10.1165/rcmb.2011-0447OC. Epub 2012 Apr 19.


PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis.

Chang HH, Tai TS, Lu B, Iannaccone C, Cernadas M, Weinblatt M, Shadick N, Miaw SC, Ho IC.

PLoS One. 2012;7(3):e33067. doi: 10.1371/journal.pone.0033067. Epub 2012 Mar 12.


Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA.

J Immunol. 2011 Nov 15;187(10):5255-67. doi: 10.4049/jimmunol.1101186. Epub 2011 Oct 3.


It takes a microbiome: commensals, immune regulation, and allergy.

Cernadas M.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):149-50. doi: 10.1164/rccm.201105-0828ED. No abstract available.


NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation.

Haworth O, Cernadas M, Levy BD.

J Immunol. 2011 Jun 1;186(11):6129-35. doi: 10.4049/jimmunol.1004007. Epub 2011 Apr 22.


Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.

Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM.

Nat Immunol. 2011 Mar;12(3):222-30. doi: 10.1038/ni.1980. Epub 2010 Dec 12.


Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected].

Muindi K, Cernadas M, Watts GF, Royle L, Neville DC, Dwek RA, Besra GS, Rudd PM, Butters TD, Brenner MB.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3052-7. doi: 10.1073/pnas.0915056107. Epub 2010 Jan 28. Erratum in: Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6118.


Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.

Kiener HP, Watts GF, Cui Y, Wright J, Thornhill TS, Sköld M, Behar SM, Niederreiter B, Lu J, Cernadas M, Coyle AJ, Sims GP, Smolen J, Warman ML, Brenner MB, Lee DM.

Arthritis Rheum. 2010 Mar;62(3):742-52. doi: 10.1002/art.27285.


Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens.

Cernadas M, Cavallari M, Watts G, Mori L, De Libero G, Brenner MB.

J Immunol. 2010 Feb 1;184(3):1235-41. doi: 10.4049/jimmunol.0804140. Epub 2009 Dec 21.


CD1a expression defines an interleukin-12 producing population of human dendritic cells.

Cernadas M, Lu J, Watts G, Brenner MB.

Clin Exp Immunol. 2009 Mar;155(3):523-33. doi: 10.1111/j.1365-2249.2008.03853.x.


Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation.

Haworth O, Cernadas M, Yang R, Serhan CN, Levy BD.

Nat Immunol. 2008 Aug;9(8):873-9. doi: 10.1038/ni.1627. Epub 2008 Jun 22.


Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice.

Robbins CS, Franco F, Mouded M, Cernadas M, Shapiro SD.

J Immunol. 2008 May 15;180(10):6623-8.


PU.1 regulates cathepsin S expression in professional APCs.

Wang Y, Baron RM, Zhu G, Joo M, Christman JW, Silverman ES, Perrella MA, Riese RJ, Cernadas M.

J Immunol. 2006 Jan 1;176(1):275-83.


New insights into pathways for CD1-mediated antigen presentation.

Sugita M, Cernadas M, Brenner MB.

Curr Opin Immunol. 2004 Feb;16(1):90-5. Review.


Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development.

Cernadas M, Sugita M, van der Wel N, Cao X, Gumperz JE, Maltsev S, Besra GS, Behar SM, Peters PJ, Brenner MB.

J Immunol. 2003 Oct 15;171(8):4149-55.


IL-6 production by pulmonary dendritic cells impedes Th1 immune responses.

Dodge IL, Carr MW, Cernadas M, Brenner MB.

J Immunol. 2003 May 1;170(9):4457-64.


Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction.

Strauch UG, Mueller RC, Li XY, Cernadas M, Higgins JM, Binion DG, Parker CM.

J Immunol. 2001 Mar 1;166(5):3506-14.


The role of alpha and beta chains in ligand recognition by beta 7 integrins.

Higgins JM, Cernadas M, Tan K, Irie A, Wang J, Takada Y, Brenner MB.

J Biol Chem. 2000 Aug 18;275(33):25652-64.


B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness.

Mark DA, Donovan CE, De Sanctis GT, He HZ, Cernadas M, Kobzik L, Perkins DL, Sharpe A, Finn PW.

Am J Respir Cell Mol Biol. 2000 Mar;22(3):265-71.


CD23 and allergic pulmonary inflammation: potential role as an inhibitor.

Cernadas M, De Sanctis GT, Krinzman SJ, Mark DA, Donovan CE, Listman JA, Kobzik L, Kikutani H, Christiani DC, Perkins DL, Finn PW.

Am J Respir Cell Mol Biol. 1999 Jan;20(1):1-8.


Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.

Cernadas MR, Sánchez de Miguel L, García-Durán M, González-Fernández F, Millás I, Montón M, Rodrigo J, Rico L, Fernández P, de Frutos T, Rodríguez-Feo JA, Guerra J, Caramelo C, Casado S, López-Farré.

Circ Res. 1998 Aug 10;83(3):279-86.


Effects of placental delivery method and intraoperative glove changing on postcesarean febrile morbidity.

Cernadas M, Smulian JC, Giannina G, Ananth CV.

J Matern Fetal Med. 1998 Mar-Apr;7(2):100-4.


Role of nitric oxide-related mechanisms in renal function in ageing rats.

Tan D, Cernadas MR, Aragoncillo P, Castilla MA, Alvarez Arroyo MV, López Farré AJ, Casado S, Caramelo C.

Nephrol Dial Transplant. 1998 Mar;13(3):594-601.


Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.

Krinzman SJ, De Sanctis GT, Cernadas M, Mark D, Wang Y, Listman J, Kobzik L, Donovan C, Nassr K, Katona I, Christiani DC, Perkins DL, Finn PW.

J Clin Invest. 1996 Dec 15;98(12):2693-9.


Role of endothelium-related mechanisms in the pathophysiology of renal ischemia/reperfusion in normal rabbits.

Caramelo C, Espinosa G, Manzarbeitia F, Cernadas MR, Pérez Tejerizo G, Tan D, Mosquera JR, Digiuni E, Montón M, Millás I, Hernando L, Casado S, López-Farré A.

Circ Res. 1996 Nov;79(5):1031-8.


Role of endothelin in the pathophysiology of renal ischemia-reperfusion in normal rabbits.

Espinosa G, López Farré A, Cernadas MR, Manzarbeitia F, Tan D, Digiuni E, Mosquera JR, Montón M, Millás I, Hernando L, Casado S, Caramelo C.

Kidney Int. 1996 Sep;50(3):776-82.


T cell activation in a murine model of asthma.

Krinzman SJ, De Sanctis GT, Cernadas M, Kobzik L, Listman JA, Christiani DC, Perkins DL, Finn PW.

Am J Physiol. 1996 Sep;271(3 Pt 1):L476-83.


Aspirin-stimulated nitric oxide production by neutrophils after acute myocardial ischemia in rabbits.

López-Farré A, Riesco A, Digiuni E, Mosquera JR, Caramelo C, de Miguel LS, Millás I, de Frutos T, Cernadas MR, Montón M, Alonso J, Casado S.

Circulation. 1996 Jul 1;94(1):83-7.


Comparison of the effects of meperidine and nalbuphine on intrapartum fetal heart rate tracings.

Giannina G, Guzman ER, Lai YL, Lake MF, Cernadas M, Vintzileos AM.

Obstet Gynecol. 1995 Sep;86(3):441-5.


Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart.

López Farré A, Riesco A, Espinosa G, Digiuni E, Cernadas MR, Alvarez V, Montón M, Rivas F, Gallego MJ, Egido J, et al.

Circulation. 1993 Sep;88(3):1166-71.


Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids.

Cernadas MR, López-Farré A, Riesco A, Gallego MJ, Espinosa G, Digiuni E, Hernando L, Casado S, Caramelo C.

J Pharmacol Exp Ther. 1992 Dec;263(3):1023-9.


Glycation alters collagen fibril organization.

Bai P, Phua K, Hardt T, Cernadas M, Brodsky B.

Connect Tissue Res. 1992;28(1-2):1-12.


Direct regulation of Na(+)-dependent myo-inositol transport by sugars in retinal pigment epithelium: role of phorbol ester and staurosporin.

Khatami M, Cernadas M, Geroff AJ, Chandra P, Cohen MF.

Membr Biochem. 1990 Oct-Dec;9(4):263-77.


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