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Items: 47

1.

Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing.

Maule G, Casini A, Montagna C, Ramalho AS, De Boeck K, Debyser Z, Carlon MS, Petris G, Cereseto A.

Nat Commun. 2019 Aug 7;10(1):3556. doi: 10.1038/s41467-019-11454-9.

2.

Post-mitotic BET-induced reshaping of integrase quaternary structure supports wild-type MLV integration.

Borrenberghs D, Zurnic I, De Wit F, Acke A, Dirix L, Cereseto A, Debyser Z, Hendrix J.

Nucleic Acids Res. 2019 Feb 20;47(3):1195-1210. doi: 10.1093/nar/gky1157.

3.

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9.

Montagna C, Petris G, Casini A, Maule G, Franceschini GM, Zanella I, Conti L, Arnoldi F, Burrone OR, Zentilin L, Zacchigna S, Giacca M, Cereseto A.

Mol Ther Nucleic Acids. 2018 Sep 7;12:453-462. doi: 10.1016/j.omtn.2018.05.010. Epub 2018 Jul 11.

4.

A highly specific SpCas9 variant is identified by in vivo screening in yeast.

Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A.

Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29.

5.

Inherited determinants of early recurrent somatic mutations in prostate cancer.

Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P, Gasperini P, Cereseto A, Elemento O, Sboner A, Khurana E, Inga A, Rubin MA, Demichelis F.

Nat Commun. 2017 Jun 29;8(1):48. doi: 10.1038/s41467-017-00046-0.

6.

Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection.

Agostini S, Ali H, Vardabasso C, Fittipaldi A, Tasciotti E, Cereseto A, Bugatti A, Rusnati M, Lusic M, Giacca M.

EBioMedicine. 2017 Jul;21:170-181. doi: 10.1016/j.ebiom.2017.06.011. Epub 2017 Jun 13.

7.

Hit and go CAS9 delivered through a lentiviral based self-limiting circuit.

Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, Zasso J, Conti L, Demichelis F, Cereseto A.

Nat Commun. 2017 May 22;8:15334. doi: 10.1038/ncomms15334.

8.

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.

Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z.

EBioMedicine. 2016 Jun;8:248-264. doi: 10.1016/j.ebiom.2016.04.039. Epub 2016 May 13.

9.

Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions.

Quercioli V, Di Primio C, Casini A, Mulder LCF, Vranckx LS, Borrenberghs D, Gijsbers R, Debyser Z, Cereseto A.

J Virol. 2016 Apr 29;90(10):5205-5209. doi: 10.1128/JVI.03188-15. Print 2016 May 15.

10.

Reduction of HIV-1 infectivity through endoplasmic reticulum-associated degradation-mediated Env depletion.

Casini A, Olivieri M, Vecchi L, Burrone OR, Cereseto A.

J Virol. 2015 Mar;89(5):2966-71. doi: 10.1128/JVI.02634-14. Epub 2014 Dec 24.

11.

Second generation imaging of nuclear/cytoplasmic HIV-1 complexes.

Francis AC, Di Primio C, Quercioli V, Valentini P, Boll A, Girelli G, Demichelis F, Arosio D, Cereseto A.

AIDS Res Hum Retroviruses. 2014 Jul;30(7):717-26. doi: 10.1089/AID.2013.0277. Epub 2014 Jun 6.

12.

CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules.

Petris G, Casini A, Sasset L, Cesaratto F, Bestagno M, Cereseto A, Burrone OR.

J Biol Chem. 2014 Jan 3;289(1):1-12. doi: 10.1074/jbc.M113.512368. Epub 2013 Nov 20.

13.

Imaging HIV-1 nuclear pre-integration complexes.

Cereseto A, Giacca M.

Methods Mol Biol. 2014;1087:47-54. doi: 10.1007/978-1-62703-670-2_5.

PMID:
24158813
14.

Single-cell imaging of HIV-1 provirus (SCIP).

Di Primio C, Quercioli V, Allouch A, Gijsbers R, Christ F, Debyser Z, Arosio D, Cereseto A.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5636-41. doi: 10.1073/pnas.1216254110. Epub 2013 Mar 19.

15.

The TRIM family protein KAP1 inhibits HIV-1 integration.

Allouch A, Di Primio C, Alpi E, Lusic M, Arosio D, Giacca M, Cereseto A.

Cell Host Microbe. 2011 Jun 16;9(6):484-95. doi: 10.1016/j.chom.2011.05.004.

16.

Role of phosphorylation in the nuclear biology of HIV-1.

Francis AC, Di Primio C, Allouch A, Cereseto A.

Curr Med Chem. 2011;18(19):2904-12. Review.

PMID:
21651489
17.

GCN5-dependent acetylation of HIV-1 integrase enhances viral integration.

Terreni M, Valentini P, Liverani V, Gutierrez MI, Di Primio C, Di Fenza A, Tozzini V, Allouch A, Albanese A, Giacca M, Cereseto A.

Retrovirology. 2010 Mar 12;7:18. doi: 10.1186/1742-4690-7-18.

18.

Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes.

Manganaro L, Lusic M, Gutierrez MI, Cereseto A, Del Sal G, Giacca M.

Nat Med. 2010 Mar;16(3):329-33. doi: 10.1038/nm.2102. Epub 2010 Feb 21.

PMID:
20173753
19.

Identification of cellular factors binding to acetylated HIV-1 integrase.

Allouch A, Cereseto A.

Amino Acids. 2011 Nov;41(5):1137-45. doi: 10.1007/s00726-009-0444-3. Epub 2009 Dec 18.

PMID:
20016921
20.

Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle.

Paolinelli R, Mendoza-Maldonado R, Cereseto A, Giacca M.

Nat Struct Mol Biol. 2009 Apr;16(4):412-20. doi: 10.1038/nsmb.1583. Epub 2009 Apr 3.

PMID:
19343071
21.

Transportin-SR2 imports HIV into the nucleus.

Christ F, Thys W, De Rijck J, Gijsbers R, Albanese A, Arosio D, Emiliani S, Rain JC, Benarous R, Cereseto A, Debyser Z.

Curr Biol. 2008 Aug 26;18(16):1192-202. doi: 10.1016/j.cub.2008.07.079.

22.

HIV-1 pre-integration complexes selectively target decondensed chromatin in the nuclear periphery.

Albanese A, Arosio D, Terreni M, Cereseto A.

PLoS One. 2008 Jun 11;3(6):e2413. doi: 10.1371/journal.pone.0002413.

23.

Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription.

Sabò A, Lusic M, Cereseto A, Giacca M.

Mol Cell Biol. 2008 Apr;28(7):2201-12. doi: 10.1128/MCB.01557-07. Epub 2008 Feb 4.

24.

Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase.

Costi R, Di Santo R, Artico M, Miele G, Valentini P, Novellino E, Cereseto A.

J Med Chem. 2007 Apr 19;50(8):1973-7. Epub 2007 Mar 10.

PMID:
17348637
25.

HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway.

Toschi E, Bacigalupo I, Strippoli R, Chiozzini C, Cereseto A, Falchi M, Nappi F, Sgadari C, Barillari G, Mainiero F, Ensoli B.

Mol Biol Cell. 2006 Apr;17(4):1985-94. Epub 2006 Jan 25.

26.

Acetylation of HIV-1 integrase by p300 regulates viral integration.

Cereseto A, Manganaro L, Gutierrez MI, Terreni M, Fittipaldi A, Lusic M, Marcello A, Giacca M.

EMBO J. 2005 Sep 7;24(17):3070-81. Epub 2005 Aug 11.

27.

Integration site selection by retroviruses.

Cereseto A, Giacca M.

AIDS Rev. 2004 Jan-Mar;6(1):13-21. Review.

PMID:
15168737
28.

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.

Lusic M, Marcello A, Cereseto A, Giacca M.

EMBO J. 2003 Dec 15;22(24):6550-61.

29.

Activation of matrix-metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability in vivo by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor.

Toschi E, Barillari G, Sgadari C, Bacigalupo I, Cereseto A, Carlei D, Palladino C, Zietz C, Leone P, Stürzl M, Buttò S, Cafaro A, Monini P, Ensoli B.

Mol Biol Cell. 2001 Oct;12(10):2934-46.

30.

Cytokine response gene 8 (CR8) regulates the cell cycle G1-S phase transition and promotes cellular survival.

Beadling C, Cereseto A, Fan W, Naramura M, Smith KA.

Oncogene. 2001 Mar 29;20(14):1771-83.

31.
32.

Mechanism of paclitaxel activity in Kaposi's sarcoma.

Sgadari C, Toschi E, Palladino C, Barillari G, Carlei D, Cereseto A, Ciccolella C, Yarchoan R, Monini P, Stürzl M, Ensoli B.

J Immunol. 2000 Jul 1;165(1):509-17.

33.

p53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cells.

Takemoto S, Trovato R, Cereseto A, Nicot C, Kislyakova T, Casareto L, Waldmann T, Torelli G, Franchini G.

Blood. 2000 Jun 15;95(12):3939-44.

PMID:
10845931
34.

Deletion of the p16INK4A gene in ex vivo acute adult T cell lymphoma/leukemia cells and methylation of the p16INK4A promoter in HTLV type I-infected T cell lines.

Trovato R, Cereseto A, Takemoto S, Gessain A, Watanabe T, Waldmann T, Franchini G.

AIDS Res Hum Retroviruses. 2000 May 20;16(8):709-13.

PMID:
10826477
35.

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.

Nicot C, Mahieux R, Opavsky R, Cereseto A, Wolff L, Brady JN, Franchini G.

Oncogene. 2000 Apr 20;19(17):2155-64.

36.

Cytokine response gene 6 induces p21 and regulates both cell growth and arrest.

Fan W, Richter G, Cereseto A, Beadling C, Smith KA.

Oncogene. 1999 Nov 11;18(47):6573-82.

37.

Differential response to genotoxic stress in immortalized or transformed human T-lymphotropic virus type I-infected T-cells.

Cereseto A, Kislyakova T, Washington Parks R, Nicot C, Franchini G.

J Gen Virol. 1999 Jul;80 ( Pt 7):1575-81.

PMID:
10423124
38.

Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells.

Cereseto A, Washington Parks R, Rivadeneira E, Franchini G.

Oncogene. 1999 Apr 15;18(15):2441-50.

39.

Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain.

Mulloy JC, Kislyakova T, Cereseto A, Casareto L, LoMonico A, Fullen J, Lorenzi MV, Cara A, Nicot C, Giam C, Franchini G.

J Virol. 1998 Nov;72(11):8852-60.

40.

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins.

Takemoto S, Mulloy JC, Cereseto A, Migone TS, Patel BK, Matsuoka M, Yamaguchi K, Takatsuki K, Kamihira S, White JD, Leonard WJ, Waldmann T, Franchini G.

Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13897-902.

41.

Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines.

Cereseto A, Berneman Z, Koralnik I, Vaughn J, Franchini G, Klotman ME.

Leukemia. 1997 Jun;11(6):866-70.

42.

p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells.

Cereseto A, Diella F, Mulloy JC, Cara A, Michieli P, Grassmann R, Franchini G, Klotman ME.

Blood. 1996 Sep 1;88(5):1551-60.

PMID:
8781409
43.

HIV-1 protein expression from synthetic circles of DNA mimicking the extrachromosomal forms of viral DNA.

Cara A, Cereseto A, Lori F, Reitz MS Jr.

J Biol Chem. 1996 Mar 8;271(10):5393-7.

44.

Insights on the pathogenicity of human T-lymphotropic/leukemia virus types I and II.

Cereseto A, Mulloy JC, Franchini G.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996;13 Suppl 1:S69-75. Review.

PMID:
8797707
45.

Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts.

Budillon A, Cereseto A, Kondrashin A, Nesterova M, Merlo G, Clair T, Cho-Chung YS.

Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10634-8.

46.

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

Migone TS, Lin JX, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard WJ.

Science. 1995 Jul 7;269(5220):79-81.

PMID:
7604283
47.

[Identification of the dystrophin gene deletions in DMD/BMD patients. Analysis of the reading frame shift and germinal mosaicism].

Covone AE, Caroli F, Cereseto A, Lerone M, Romeo G.

Minerva Pediatr. 1991 Mar;43(3):65-6. Italian. No abstract available.

PMID:
1870527

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