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Items: 1 to 50 of 146

1.

Real-time optical manipulation of cardiac conduction in intact hearts.

Scardigli M, Müllenbroich C, Margoni E, Cannazzaro S, Crocini C, Ferrantini C, Coppini R, Yan P, Loew LM, Campione M, Bocchi L, Giulietti D, Cerbai E, Poggesi C, Bub G, Pavone FS, Sacconi L.

J Physiol. 2018 Sep;596(17):3841-3858. doi: 10.1113/JP276283. Epub 2018 Aug 7.

2.

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.

Bua S, Berrino E, Del Prete S, Murthy VS, Vijayakumar V, Tamboli Y, Capasso C, Cerbai E, Mugelli A, Carta F, Supuran CT.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1125-1136. doi: 10.1080/14756366.2018.1467901.

3.

Hyperpolarization-activated cyclic-nucleotide-gated channels: pathophysiological, developmental, and pharmacological insights into their function in cellular excitability.

Spinelli V, Sartiani L, Mugelli A, Romanelli MN, Cerbai E.

Can J Physiol Pharmacol. 2018 Jul 3:1-8. doi: 10.1139/cjpp-2018-0115. [Epub ahead of print]

PMID:
29969572
4.

Lercanidipine and T-type calcium current.

Cerbai E, Mugelli A.

Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):4025-4031. doi: 10.26355/eurrev_201806_15289.

PMID:
29949180
5.

Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center.

Mazzarotto F, Girolami F, Boschi B, Barlocco F, Tomberli A, Baldini K, Coppini R, Tanini I, Bardi S, Contini E, Cecchi F, Pelo E, Cook SA, Cerbai E, Poggesi C, Torricelli F, Walsh R, Olivotto I.

Genet Med. 2018 Jun 6. doi: 10.1038/s41436-018-0046-0. [Epub ahead of print]

PMID:
29875424
6.

Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.

Ferrantini C, Pioner JM, Mazzoni L, Gentile F, Tosi B, Rossi A, Belardinelli L, Tesi C, Palandri C, Matucci R, Cerbai E, Olivotto I, Poggesi C, Mugelli A, Coppini R.

Br J Pharmacol. 2018 Jul;175(13):2635-2652. doi: 10.1111/bph.14223. Epub 2018 May 3.

7.

Sex-related differences in chronic heart failure.

Aimo A, Vergaro G, Barison A, Maffei S, Borrelli C, Morrone D, Cameli M, Palazzuoli A, Ambrosio G, Coiro S, Savino K, Cerbai E, Marcucci R, Pedrinelli R, Padeletti L, Passino C, Emdin M.

Int J Cardiol. 2018 Mar 15;255:145-151. doi: 10.1016/j.ijcard.2017.10.068.

PMID:
29425552
8.

Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy.

Resta F, Micheli L, Laurino A, Spinelli V, Mello T, Sartiani L, Di Cesare Mannelli L, Cerbai E, Ghelardini C, Romanelli MN, Mannaioni G, Masi A.

Neuropharmacology. 2018 Mar 15;131:403-413. doi: 10.1016/j.neuropharm.2018.01.014. Epub 2018 Jan 12.

PMID:
29339292
9.

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E562-E563. doi: 10.1073/pnas.1720253115. Epub 2018 Jan 5. No abstract available.

10.

The importance of integrated left atrial evaluation: From hypertension to heart failure with preserved ejection fraction.

Beltrami M, Palazzuoli A, Padeletti L, Cerbai E, Coiro S, Emdin M, Marcucci R, Morrone D, Cameli M, Savino K, Pedrinelli R, Ambrosio G; Società Italiana di Cardiologia, Sezione Regionale Tosco-Umbra.

Int J Clin Pract. 2018 Feb;72(2). doi: 10.1111/ijcp.13050. Epub 2017 Dec 28. Review.

PMID:
29283475
11.

Arterial hypertension and atrial fibrillation: standard and advanced echocardiography from diagnosis to prognostication.

Cameli M, Mandoli GE, Ambrosio G, Cerbai E, Coiro S, Emdin M, Marcucci R, Morrone D, Palazzuoli A, Savino K, Padeletti L, Mondillo S, Pedrinelli R; Società Italiana di Cardiologia, Sezione Regionale Tosco-Umbra.

J Cardiovasc Med (Hagerstown). 2018 Feb;19(2):51-61. doi: 10.2459/JCM.0000000000000607. Review.

PMID:
29251696
12.

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy.

Zaglia T, Ceriotti P, Campo A, Borile G, Armani A, Carullo P, Prando V, Coppini R, Vida V, Stølen TO, Ulrik W, Cerbai E, Stellin G, Faggian G, De Stefani D, Sandri M, Rizzuto R, Di Lisa F, Pozzan T, Catalucci D, Mongillo M.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9006-E9015. doi: 10.1073/pnas.1708772114. Epub 2017 Oct 9.

13.

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair.

Martella D, Paoli P, Pioner JM, Sacconi L, Coppini R, Santini L, Lulli M, Cerbai E, Wiersma DS, Poggesi C, Ferrantini C, Parmeggiani C.

Small. 2017 Dec;13(46). doi: 10.1002/smll.201702677. Epub 2017 Oct 17.

PMID:
29045016
14.

Resistant hypertension: an overview.

Pedrinelli R, Dell'omo G, Cameli M, Cerbai E, Coiro S, Emdin M, Liga R, Marcucci R, Morrone D, Palazzuoli A, Savino K, Padeletti L, Ambrosio G; Società Italiana di Cardiologia, Sezione Regionale Tosco-Umbra.

Minerva Cardioangiol. 2018 Jun;66(3):337-348. doi: 10.23736/S0026-4725.17.04495-4. Epub 2017 Sep 5.

PMID:
28880055
15.

The Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: from Biophysics to Pharmacology of a Unique Family of Ion Channels.

Sartiani L, Mannaioni G, Masi A, Novella Romanelli M, Cerbai E.

Pharmacol Rev. 2017 Oct;69(4):354-395. doi: 10.1124/pr.117.014035. Review.

PMID:
28878030
16.

Myocardial 123I-metaiodobenzylguanidine imaging in hypertension and left ventricular hypertrophy.

Liga R, Gimelli A, Marzullo P, Ambrosio G, Cameli M, Cerbai E, Coiro S, Emdin M, Marcucci R, Morrone D, Palazzuoli A, Petronio AS, Savino K, Padeletti L, Pedrinelli R; Società Italiana di Cardiologia, Sezione Regionale Tosco-Umbra.

J Nucl Cardiol. 2018 Apr;25(2):461-470. doi: 10.1007/s12350-017-1029-2. Epub 2017 Aug 10.

PMID:
28798990
17.

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

Ferrantini C, Coppini R, Pioner JM, Gentile F, Tosi B, Mazzoni L, Scellini B, Piroddi N, Laurino A, Santini L, Spinelli V, Sacconi L, De Tombe P, Moore R, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Tesi C, Poggesi C.

J Am Heart Assoc. 2017 Jul 22;6(7). pii: e005407. doi: 10.1161/JAHA.116.005407.

18.

Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.

Berrino E, Bua S, Mori M, Botta M, Murthy VS, Vijayakumar V, Tamboli Y, Bartolucci G, Mugelli A, Cerbai E, Supuran CT, Carta F.

Molecules. 2017 Jun 24;22(7). pii: E1049. doi: 10.3390/molecules22071049.

19.

The effects of gender on electrical therapies for the heart: physiology, epidemiology, and access to therapies.

Boriani G, Lorenzetti S, Cerbai E, Oreto G, Bronzetti G, Malavasi VL, Biffi A, Padeletti L, Botto G, Diemberger I.

Europace. 2017 Sep 1;19(9):1418-1426. doi: 10.1093/europace/eux068. Review.

PMID:
28525585
20.

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):5737-5742. doi: 10.1073/pnas.1702188114. Epub 2017 May 15.

21.

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

Coppini R, Mazzoni L, Ferrantini C, Gentile F, Pioner JM, Laurino A, Santini L, Bargelli V, Rotellini M, Bartolucci G, Crocini C, Sacconi L, Tesi C, Belardinelli L, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Poggesi C.

Circ Heart Fail. 2017 Mar;10(3). pii: e003565. doi: 10.1161/CIRCHEARTFAILURE.116.003565.

PMID:
28255011
22.

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes.

Sartiani L, Bucciantini M, Spinelli V, Leri M, Natalello A, Nosi D, Maria Doglia S, Relini A, Penco A, Giorgetti S, Gerace E, Mannaioni G, Bellotti V, Rigacci S, Cerbai E, Stefani M.

Biophys J. 2016 Nov 1;111(9):2024-2038. doi: 10.1016/j.bpj.2016.09.010.

23.

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

Crocini C, Ferrantini C, Coppini R, Scardigli M, Yan P, Loew LM, Smith G, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Sci Rep. 2016 Oct 17;6:35628. doi: 10.1038/srep35628.

24.

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Poggesi C, Cerbai E, Pavone FS, Sacconi L.

Int J Mol Sci. 2016 Sep 3;17(9). pii: E1471. doi: 10.3390/ijms17091471.

25.

Frontiers in Cardiovascular Biology: a forum for exploratory basic science and translational research from the ESC Council for Basic Cardiovascular Sciences.

Cerbai E, Sipido KR, Badimon L.

Cardiovasc Res. 2016 Jul 15;111(2):119. doi: 10.1093/cvr/cvw157. Epub 2016 Jun 10. No abstract available.

PMID:
27288010
26.

HCN Channels Modulators: The Need for Selectivity.

Novella Romanelli M, Sartiani L, Masi A, Mannaioni G, Manetti D, Mugelli A, Cerbai E.

Curr Top Med Chem. 2016;16(16):1764-91. Review.

27.

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

Crocini C, Ferrantini C, Scardigli M, Coppini R, Mazzoni L, Lazzeri E, Pioner JM, Scellini B, Guo A, Song LS, Yan P, Loew LM, Tardiff J, Tesi C, Vanzi F, Cerbai E, Pavone FS, Sacconi L, Poggesi C.

J Mol Cell Cardiol. 2016 Feb;91:42-51. doi: 10.1016/j.yjmcc.2015.12.013. Epub 2015 Dec 20.

28.

R4496C RyR2 mutation impairs atrial and ventricular contractility.

Ferrantini C, Coppini R, Scellini B, Ferrara C, Pioner JM, Mazzoni L, Priori S, Cerbai E, Tesi C, Poggesi C.

J Gen Physiol. 2016 Jan;147(1):39-52. doi: 10.1085/jgp.201511450. Epub 2015 Dec 14.

29.

Pharmacological perspectives in sarcopenia: a potential role for renin-angiotensin system blockers?

Sartiani L, Spinelli V, Laurino A, Blescia S, Raimondi L, Cerbai E, Mugelli A.

Clin Cases Miner Bone Metab. 2015 May-Aug;12(2):135-8. doi: 10.11138/ccmbm/2015.12.2.135. Epub 2015 Oct 26. Review.

30.

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy.

Passini E, Mincholé A, Coppini R, Cerbai E, Rodriguez B, Severi S, Bueno-Orovio A.

J Mol Cell Cardiol. 2016 Jul;96:72-81. doi: 10.1016/j.yjmcc.2015.09.003. Epub 2015 Sep 16.

31.

Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology.

Sartiani L, Romanelli MN, Mugelli A, Cerbai E.

Curr Drug Targets. 2015;16(8):868-76. Review.

PMID:
26028050
32.

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15196-201. doi: 10.1073/pnas.1411557111. Epub 2014 Oct 6.

33.

Impact of detubulation on force and kinetics of cardiac muscle contraction.

Ferrantini C, Coppini R, Sacconi L, Tosi B, Zhang ML, Wang GL, de Vries E, Hoppenbrouwers E, Pavone F, Cerbai E, Tesi C, Poggesi C, ter Keurs HE.

J Gen Physiol. 2014 Jun;143(6):783-97. doi: 10.1085/jgp.201311125.

34.

Isolation and functional characterization of human ventricular cardiomyocytes from fresh surgical samples.

Coppini R, Ferrantini C, Aiazzi A, Mazzoni L, Sartiani L, Mugelli A, Poggesi C, Cerbai E.

J Vis Exp. 2014 Apr 21;(86). doi: 10.3791/51116.

35.

Altered calcium regulation in isolated cardiomyocytes from Egr-1 knock-out mice.

Pacini L, Suffredini S, Ponti D, Coppini R, Frati G, Ragona G, Cerbai E, Calogero A.

Can J Physiol Pharmacol. 2013 Dec;91(12):1135-42. doi: 10.1139/cjpp-2012-0419. Epub 2013 Sep 5.

PMID:
24289086
36.

Response to letter regarding article, "Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy".

Coppini R, Ferrantini C, Del Lungo M, Stillitano F, Sartiani L, Tosi B, Suffredini S, Tesi C, Poggesi C, Cerbai E, Mugelli A, Yao L, Fan P, Belardinelli L, Yacoub M, Olivotto I.

Circulation. 2013 Sep 3;128(10):e157. doi: 10.1161/CIRCULATIONAHA.113.004016. No abstract available.

PMID:
24002721
37.

Human amniotic fluid stem cell differentiation along smooth muscle lineage.

Ghionzoli M, Repele A, Sartiani L, Costanzi G, Parenti A, Spinelli V, David AL, Garriboli M, Totonelli G, Tian J, Andreadis ST, Cerbai E, Mugelli A, Messineo A, Pierro A, Eaton S, De Coppi P.

FASEB J. 2013 Dec;27(12):4853-65. doi: 10.1096/fj.12-218578. Epub 2013 Aug 30.

PMID:
23995291
38.

Chronic atrial fibrillation alters the functional properties of If in the human atrium.

Stillitano F, Lonardo G, Giunti G, Del Lungo M, Coppini R, Spinelli V, Sartiani L, Poggesi C, Mugelli A, Cerbai E.

J Cardiovasc Electrophysiol. 2013 Dec;24(12):1391-400. doi: 10.1111/jce.12212. Epub 2013 Jul 19.

PMID:
23869794
39.

The transverse-axial tubular system of cardiomyocytes.

Ferrantini C, Crocini C, Coppini R, Vanzi F, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Cell Mol Life Sci. 2013 Dec;70(24):4695-710. doi: 10.1007/s00018-013-1410-5. Epub 2013 Jul 12. Review.

PMID:
23846763
40.

Molecular and functional evidence of HCN4 and caveolin-3 interaction during cardiomyocyte differentiation from human embryonic stem cells.

Bosman A, Sartiani L, Spinelli V, Del Lungo M, Stillitano F, Nosi D, Mugelli A, Cerbai E, Jaconi M.

Stem Cells Dev. 2013 Jun 1;22(11):1717-27. doi: 10.1089/scd.2012.0247. Epub 2013 Feb 27.

41.

Regulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatment.

Coppini R, Ferrantini C, Mazzoni L, Sartiani L, Olivotto I, Poggesi C, Cerbai E, Mugelli A.

Glob Cardiol Sci Pract. 2013 Nov 1;2013(3):222-42. doi: 10.5339/gcsp.2013.30. eCollection 2013. Review.

42.

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy.

Coppini R, Ferrantini C, Yao L, Fan P, Del Lungo M, Stillitano F, Sartiani L, Tosi B, Suffredini S, Tesi C, Yacoub M, Olivotto I, Belardinelli L, Poggesi C, Cerbai E, Mugelli A.

Circulation. 2013 Feb 5;127(5):575-84. doi: 10.1161/CIRCULATIONAHA.112.134932. Epub 2012 Dec 27.

PMID:
23271797
43.

Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes.

Paci M, Sartiani L, Del Lungo M, Jaconi M, Mugelli A, Cerbai E, Severi S.

Biomed Eng Online. 2012 Aug 28;11:61. doi: 10.1186/1475-925X-11-61.

44.

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Sacconi L, Ferrantini C, Lotti J, Coppini R, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5815-9. doi: 10.1073/pnas.1120188109. Epub 2012 Mar 26.

45.

Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.

Del Lungo M, Melchiorre M, Guandalini L, Sartiani L, Mugelli A, Koncz I, Szel T, Varro A, Romanelli MN, Cerbai E.

Br J Pharmacol. 2012 May;166(2):602-16. doi: 10.1111/j.1476-5381.2011.01782.x.

46.

Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression.

Suffredini S, Stillitano F, Comini L, Bouly M, Brogioni S, Ceconi C, Ferrari R, Mugelli A, Cerbai E.

Br J Pharmacol. 2012 Mar;165(5):1457-66. doi: 10.1111/j.1476-5381.2011.01627.x.

47.

Electrophysiological effects of ivabradine in dog and human cardiac preparations: potential antiarrhythmic actions.

Koncz I, Szél T, Bitay M, Cerbai E, Jaeger K, Fülöp F, Jost N, Virág L, Orvos P, Tálosi L, Kristóf A, Baczkó I, Papp JG, Varró A.

Eur J Pharmacol. 2011 Oct 15;668(3):419-26. doi: 10.1016/j.ejphar.2011.07.025. Epub 2011 Aug 2.

PMID:
21821019
48.

Selective pharmacological inhibition of the pacemaker channel isoforms (HCN1-4) as new possible therapeutical targets.

Koncz I, Szél T, Jaeger K, Baczkó I, Cerbai E, Romanelli MN, Gy Papp J, Varró A.

Curr Med Chem. 2011;18(24):3662-74.

PMID:
21774761
49.

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.

Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, Fink M, Fischmeister R, Franz MR, Garny A, Giles WR, Hannes T, Harding SE, Hunter PJ, Iribe G, Jalife J, Johnson CR, Kass RS, Kodama I, Koren G, Lord P, Markhasin VS, Matsuoka S, McCulloch AD, Mirams GR, Morley GE, Nattel S, Noble D, Olesen SP, Panfilov AV, Trayanova NA, Ravens U, Richard S, Rosenbaum DS, Rudy Y, Sachs F, Sachse FB, Saint DA, Schotten U, Solovyova O, Taggart P, Tung L, Varró A, Volders PG, Wang K, Weiss JN, Wettwer E, White E, Wilders R, Winslow RL, Kohl P.

Prog Biophys Mol Biol. 2011 Oct;107(1):4-10. doi: 10.1016/j.pbiomolbio.2011.07.001. Epub 2011 Jul 6.

50.

Growth factor-induced mobilization of cardiac progenitor cells reduces the risk of arrhythmias, in a rat model of chronic myocardial infarction.

Bocchi L, Savi M, Graiani G, Rossi S, Agnetti A, Stillitano F, Lagrasta C, Baruffi S, Berni R, Frati C, Vassalle M, Squarcia U, Cerbai E, Macchi E, Stilli D, Quaini F, Musso E.

PLoS One. 2011 Mar 18;6(3):e17750. doi: 10.1371/journal.pone.0017750.

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