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Items: 5

1.

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin.

Lowe JD, Celver JP, Gurevich VV, Chavkin C.

J Biol Chem. 2002 May 3;277(18):15729-35. Epub 2002 Feb 22.

2.

Regulation of opioid receptor function by chronic agonist exposure: constitutive activity and desensitization.

Chavkin C, McLaughlin JP, Celver JP.

Mol Pharmacol. 2001 Jul;60(1):20-5. Review. No abstract available.

PMID:
11408596
3.

Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes.

Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C.

J Biol Chem. 2001 Feb 16;276(7):4894-900. Epub 2000 Nov 1.

4.

Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization.

Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K.

J Neurosci. 1999 May 15;19(10):3773-80.

5.

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