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Items: 8

1.

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.

Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaar8356. doi: 10.1126/scitranslmed.aar8356.

2.

Local and Systemic CD4+ T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis.

Hawkins C, Shaginurova G, Shelton DA, Herazo-Maya JD, Oswald-Richter KA, Rotsinger JE, Young A, Celada LJ, Kaminski N, Sevin C, Drake WP.

J Immunol Res. 2017;2017:3642832. doi: 10.1155/2017/3642832. Epub 2017 Nov 6.

3.

Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4+ T Cell Proliferation.

Celada LJ, Rotsinger JE, Young A, Shaginurova G, Shelton D, Hawkins C, Drake WP.

Am J Respir Cell Mol Biol. 2017 Jan;56(1):74-82. doi: 10.1165/rcmb.2016-0037OC.

4.

Molecular Analysis of Sarcoidosis Granulomas Reveals Antimicrobial Targets.

Rotsinger JE, Celada LJ, Polosukhin VV, Atkinson JB, Drake WP.

Am J Respir Cell Mol Biol. 2016 Jul;55(1):128-34. doi: 10.1165/rcmb.2015-0212OC.

5.

The Etiologic Role of Infectious Antigens in Sarcoidosis Pathogenesis.

Celada LJ, Hawkins C, Drake WP.

Clin Chest Med. 2015 Dec;36(4):561-8. doi: 10.1016/j.ccm.2015.08.001. Epub 2015 Sep 19. Review.

6.

Targeting CD4(+) T cells for the treatment of sarcoidosis: a promising strategy?

Celada LJ, Drake WP.

Immunotherapy. 2015;7(1):57-66. doi: 10.2217/imt.14.103. Review.

7.

Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.

Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP.

Am J Respir Crit Care Med. 2014 Sep 1;190(5):560-71. doi: 10.1164/rccm.201401-0188OC.

8.

Effects of butyltins on mitogen-activated-protein kinase kinase kinase and Ras activity in human natural killer cells.

Celada LJ, Whalen MM.

J Appl Toxicol. 2014 Sep;34(9):1002-11. doi: 10.1002/jat.2921. Epub 2013 Sep 5.

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