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Items: 1 to 50 of 62


Vancomycin-Arginine Conjugate Inhibits Growth of Carbapenem-Resistant E. coli and Targets Cell-Wall Synthesis.

Antonoplis A, Zang X, Wegner T, Wender PA, Cegelski L.

ACS Chem Biol. 2019 Sep 20;14(9):2065-2070. doi: 10.1021/acschembio.9b00565. Epub 2019 Sep 12.


Unraveling Escherichia coli's Cloak: Identification of Phosphoethanolamine Cellulose, Its Functions, and Applications.

Jeffries J, Fuller GG, Cegelski L.

Microbiol Insights. 2019 Jul 30;12:1178636119865234. doi: 10.1177/1178636119865234. eCollection 2019.


Carbon compositional analysis of hydrogel contact lenses by solid-state NMR spectroscopy.

Rabiah NI, Romaniuk JAH, Fuller GG, Scales CW, Cegelski L.

Solid State Nucl Magn Reson. 2019 Oct;102:47-52. doi: 10.1016/j.ssnmr.2019.07.003. Epub 2019 Jul 18.


Functional Specialization in Vibrio cholerae Diguanylate Cyclases: Distinct Modes of Motility Suppression and c-di-GMP Production.

Zamorano-Sánchez D, Xian W, Lee CK, Salinas M, Thongsomboon W, Cegelski L, Wong GCL, Yildiz FH.

MBio. 2019 Apr 23;10(2). pii: e00670-19. doi: 10.1128/mBio.00670-19.


Benzoladderene Mechanophores: Synthesis, Polymerization, and Mechanochemical Transformation.

Yang J, Horst M, Romaniuk JAH, Jin Z, Cegelski L, Xia Y.

J Am Chem Soc. 2019 Apr 24;141(16):6479-6483. doi: 10.1021/jacs.9b01736. Epub 2019 Apr 16.


Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli.

Beebout CJ, Eberly AR, Werby SH, Reasoner SA, Brannon JR, De S, Fitzgerald MJ, Huggins MM, Clayton DB, Cegelski L, Hadjifrangiskou M.

MBio. 2019 Apr 2;10(2). pii: e02400-18. doi: 10.1128/mBio.02400-18.


Integration of electron microscopy and solid-state NMR analysis for new views and compositional parameters of Aspergillus fumigatus biofilms.

Reichhardt C, Joubert LM, Clemons KV, Stevens DA, Cegelski L.

Med Mycol. 2019 Apr 1;57(Supplement_2):S239-S244. doi: 10.1093/mmy/myy140. Review.


A Dual-Function Antibiotic-Transporter Conjugate Exhibits Superior Activity in Sterilizing MRSA Biofilms and Killing Persister Cells.

Antonoplis A, Zang X, Huttner MA, Chong KKL, Lee YB, Co JY, Amieva MR, Kline KA, Wender PA, Cegelski L.

J Am Chem Soc. 2018 Nov 28;140(47):16140-16151. doi: 10.1021/jacs.8b08711. Epub 2018 Nov 14.


Phosphoethanolamine cellulose enhances curli-mediated adhesion of uropathogenic Escherichia coli to bladder epithelial cells.

Hollenbeck EC, Antonoplis A, Chai C, Thongsomboon W, Fuller GG, Cegelski L.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10106-10111. doi: 10.1073/pnas.1801564115. Epub 2018 Sep 19.


Synthesis and Mechanochemical Activation of Ladderene-Norbornene Block Copolymers.

Su JK, Feist JD, Yang J, Mercer JAM, Romaniuk JAH, Chen Z, Cegelski L, Burns NZ, Xia Y.

J Am Chem Soc. 2018 Oct 3;140(39):12388-12391. doi: 10.1021/jacs.8b08908. Epub 2018 Sep 20.


The Congo red derivative FSB binds to curli amyloid fibers and specifically stains curliated E. coli.

Reichhardt C, Cegelski L.

PLoS One. 2018 Aug 30;13(8):e0203226. doi: 10.1371/journal.pone.0203226. eCollection 2018.


Spectral comparisons of mammalian cells and intact organelles by solid-state NMR.

Werby SH, Cegelski L.

J Struct Biol. 2019 Apr 1;206(1):49-54. doi: 10.1016/j.jsb.2018.05.007. Epub 2018 May 30.


Peptidoglycan and Teichoic Acid Levels and Alterations in Staphylococcus aureus by Cell-Wall and Whole-Cell Nuclear Magnetic Resonance.

Romaniuk JAH, Cegelski L.

Biochemistry. 2018 Jul 3;57(26):3966-3975. doi: 10.1021/acs.biochem.8b00495. Epub 2018 Jun 11.


REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment.

Yang H, Staveness D, Ryckbosch SM, Axtman AD, Loy BA, Barnes AB, Pande VS, Schaefer J, Wender PA, Cegelski L.

ACS Cent Sci. 2018 Jan 24;4(1):89-96. doi: 10.1021/acscentsci.7b00475. Epub 2018 Jan 2.


Phosphoethanolamine cellulose: A naturally produced chemically modified cellulose.

Thongsomboon W, Serra DO, Possling A, Hadjineophytou C, Hengge R, Cegelski L.

Science. 2018 Jan 19;359(6373):334-338. doi: 10.1126/science.aao4096.


Whole-Cell Detection of C-P Bonds in Bacteria.

Bartlett C, Bansal S, Burnett A, Suits MD, Schaefer J, Cegelski L, Horsman GP, Weadge JT.

Biochemistry. 2017 Nov 7;56(44):5870-5873. doi: 10.1021/acs.biochem.7b00814.


Pseudomonas phage inhibition of Candida albicans.

Nazik H, Joubert LM, Secor PR, Sweere JM, Bollyky PL, Sass G, Cegelski L, Stevens DA.

Microbiology. 2017 Nov;163(11):1568-1577. doi: 10.1099/mic.0.000539. Epub 2017 Oct 6.


Whole Ribosome NMR: Dipolar Couplings and Contributions to Whole Cells.

Nygaard R, Romaniuk JAH, Rice DM, Cegelski L.

J Phys Chem B. 2017 Oct 12;121(40):9331-9335. doi: 10.1021/acs.jpcb.7b06736. Epub 2017 Sep 29.


Mechanochemical unzipping of insulating polyladderene to semiconducting polyacetylene.

Chen Z, Mercer JAM, Zhu X, Romaniuk JAH, Pfattner R, Cegelski L, Martinez TJ, Burns NZ, Xia Y.

Science. 2017 Aug 4;357(6350):475-479. doi: 10.1126/science.aan2797.


Disentangling Nanonets: Human α-Defensin 6 Targets Candida albicans Virulence.

Cegelski L.

Biochemistry. 2017 Feb 28;56(8):1027-1028. doi: 10.1021/acs.biochem.7b00062. Epub 2017 Feb 15. No abstract available.


Visualization of Aspergillus fumigatus biofilms with Scanning Electron Microscopy and Variable Pressure-Scanning Electron Microscopy: A comparison of processing techniques.

Joubert LM, Ferreira JA, Stevens DA, Nazik H, Cegelski L.

J Microbiol Methods. 2017 Jan;132:46-55. doi: 10.1016/j.mimet.2016.11.002. Epub 2016 Nov 9.


Cell-Based High-Throughput Screening Identifies Rifapentine as an Inhibitor of Amyloid and Biofilm Formation in Escherichia coli.

Maher MC, Lim JY, Gunawan C, Cegelski L.

ACS Infect Dis. 2015 Oct 9;1(10):460-8. doi: 10.1021/acsinfecdis.5b00055. Epub 2015 Aug 11.


Influence of the amyloid dye Congo red on curli, cellulose, and the extracellular matrix in E. coli during growth and matrix purification.

Reichhardt C, McCrate OA, Zhou X, Lee J, Thongsomboon W, Cegelski L.

Anal Bioanal Chem. 2016 Nov;408(27):7709-7717. Epub 2016 Aug 31.


Fungal biofilm composition and opportunities in drug discovery.

Reichhardt C, Stevens DA, Cegelski L.

Future Med Chem. 2016 Aug;8(12):1455-68. doi: 10.4155/fmc-2016-0049. Epub 2016 Aug 3. Review.


Mechanical Behavior of a Bacillus subtilis Pellicle.

Hollenbeck EC, Douarche C, Allain JM, Roger P, Regeard C, Cegelski L, Fuller GG, Raspaud E.

J Phys Chem B. 2016 Jul 7;120(26):6080-8. doi: 10.1021/acs.jpcb.6b02074. Epub 2016 Apr 15.


C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae.

Jones CJ, Utada A, Davis KR, Thongsomboon W, Zamorano Sanchez D, Banakar V, Cegelski L, Wong GC, Yildiz FH.

PLoS Pathog. 2015 Oct 27;11(10):e1005068. doi: 10.1371/journal.ppat.1005068. eCollection 2015 Oct.


Frequency-selective REDOR and spin-diffusion relays in uniformly labeled whole cells.

Rice DM, Romaniuk JA, Cegelski L.

Solid State Nucl Magn Reson. 2015 Nov;72:132-9. doi: 10.1016/j.ssnmr.2015.10.008. Epub 2015 Oct 14.


Congo Red Interactions with Curli-Producing E. coli and Native Curli Amyloid Fibers.

Reichhardt C, Jacobson AN, Maher MC, Uang J, McCrate OA, Eckart M, Cegelski L.

PLoS One. 2015 Oct 20;10(10):e0140388. doi: 10.1371/journal.pone.0140388. eCollection 2015.


Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR.

Romaniuk JA, Cegelski L.

Philos Trans R Soc Lond B Biol Sci. 2015 Oct 5;370(1679). pii: 20150024. doi: 10.1098/rstb.2015.0024. Review.


Analysis of the Aspergillus fumigatus Biofilm Extracellular Matrix by Solid-State Nuclear Magnetic Resonance Spectroscopy.

Reichhardt C, Ferreira JA, Joubert LM, Clemons KV, Stevens DA, Cegelski L.

Eukaryot Cell. 2015 Nov;14(11):1064-72. doi: 10.1128/EC.00050-15. Epub 2015 Jul 10.


Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR.

Nygaard R, Romaniuk JAH, Rice DM, Cegelski L.

Biophys J. 2015 Mar 24;108(6):1380-1389. doi: 10.1016/j.bpj.2015.01.037.


Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition.

Cegelski L.

J Magn Reson. 2015 Apr;253:91-7. doi: 10.1016/j.jmr.2015.01.014.


Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy.

Loy BA, Lesser AB, Staveness D, Billingsley KL, Cegelski L, Wender PA.

J Am Chem Soc. 2015 Mar 18;137(10):3678-85. doi: 10.1021/jacs.5b00886. Epub 2015 Mar 4.


Molecular determinants of mechanical properties of V. cholerae biofilms at the air-liquid interface.

Hollenbeck EC, Fong JC, Lim JY, Yildiz FH, Fuller GG, Cegelski L.

Biophys J. 2014 Nov 18;107(10):2245-52. doi: 10.1016/j.bpj.2014.10.015.


NMR spectroscopy for atomistic views of biomembranes and cell surfaces.

Cegelski L, Weliky DP.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt B):201-2. doi: 10.1016/j.bbamem.2014.10.010. Epub 2014 Oct 7. No abstract available.


Solid-State NMR for Bacterial Biofilms.

Reichhardt C, Cegelski L.

Mol Phys. 2014 Apr 3;112(7):887-894.


Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approach.

Reichhardt C, Fong JC, Yildiz F, Cegelski L.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt B):378-83. doi: 10.1016/j.bbamem.2014.05.030. Epub 2014 Jun 7.


Putative hydrogen bond to tyrosine M208 in photosynthetic reaction centers from Rhodobacter capsulatus significantly slows primary charge separation.

Saggu M, Carter B, Zhou X, Faries K, Cegelski L, Holten D, Boxer SG, Kirmaier C.

J Phys Chem B. 2014 Jun 19;118(24):6721-32. doi: 10.1021/jp503422c. Epub 2014 Jun 6.


Community behavior and amyloid-associated phenotypes among a panel of uropathogenic E. coli.

Lim JY, Pinkner JS, Cegelski L.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):345-50. doi: 10.1016/j.bbrc.2013.11.026. Epub 2013 Nov 15.


REDOR NMR for drug discovery.

Cegelski L.

Bioorg Med Chem Lett. 2013 Nov 1;23(21):5767-75. doi: 10.1016/j.bmcl.2013.08.064. Epub 2013 Aug 22.


Sum of the parts: composition and architecture of the bacterial extracellular matrix.

McCrate OA, Zhou X, Reichhardt C, Cegelski L.

J Mol Biol. 2013 Nov 15;425(22):4286-94. doi: 10.1016/j.jmb.2013.06.022. Epub 2013 Jul 1.


Curcumin as an amyloid-indicator dye in E. coli.

McCrate OA, Zhou X, Cegelski L.

Chem Commun (Camb). 2013 May 14;49(39):4193-5. doi: 10.1039/c2cc37792f. Epub 2013 Jan 4.


Disruption of Escherichia coli amyloid-integrated biofilm formation at the air-liquid interface by a polysorbate surfactant.

Wu C, Lim JY, Fuller GG, Cegelski L.

Langmuir. 2013 Jan 22;29(3):920-6. doi: 10.1021/la304710k. Epub 2013 Jan 9.


Nutrient-dependent structural changes in S. aureus peptidoglycan revealed by solid-state NMR spectroscopy.

Zhou X, Cegelski L.

Biochemistry. 2012 Oct 16;51(41):8143-53. doi: 10.1021/bi3012115. Epub 2012 Oct 2.


Quantitative analysis of amyloid-integrated biofilms formed by uropathogenic Escherichia coli at the air-liquid interface.

Wu C, Lim JY, Fuller GG, Cegelski L.

Biophys J. 2012 Aug 8;103(3):464-71. doi: 10.1016/j.bpj.2012.06.049.


Dimethyl sulfoxide and ethanol elicit increased amyloid biogenesis and amyloid-integrated biofilm formation in Escherichia coli.

Lim JY, May JM, Cegelski L.

Appl Environ Microbiol. 2012 May;78(9):3369-78. doi: 10.1128/AEM.07743-11. Epub 2012 Mar 2.


Plant cell-wall cross-links by REDOR NMR spectroscopy.

Cegelski L, O'Connor RD, Stueber D, Singh M, Poliks B, Schaefer J.

J Am Chem Soc. 2010 Nov 17;132(45):16052-7. doi: 10.1021/ja104827k. Epub 2010 Oct 21.


Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation.

Cegelski L, Pinkner JS, Hammer ND, Cusumano CK, Hung CS, Chorell E, Aberg V, Walker JN, Seed PC, Almqvist F, Chapman MR, Hultgren SJ.

Nat Chem Biol. 2009 Dec;5(12):913-9. doi: 10.1038/nchembio.242. Epub 2009 Oct 25.


Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus.

Kim SJ, Cegelski L, Stueber D, Singh M, Dietrich E, Tanaka KS, Parr TR Jr, Far AR, Schaefer J.

J Mol Biol. 2008 Mar 14;377(1):281-93. doi: 10.1016/j.jmb.2008.01.031. Epub 2008 Jan 17.


Morphological plasticity as a bacterial survival strategy.

Justice SS, Hunstad DA, Cegelski L, Hultgren SJ.

Nat Rev Microbiol. 2008 Feb;6(2):162-8. Review.


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