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Items: 24


Small heat shock proteins: multifaceted proteins with important implications for life.

Carra S, Alberti S, Benesch JLP, Boelens W, Buchner J, Carver JA, Cecconi C, Ecroyd H, Gusev N, Hightower LE, Klevit RE, Lee HO, Liberek K, Lockwood B, Poletti A, Timmerman V, Toth ME, Vierling E, Wu T, Tanguay RM.

Cell Stress Chaperones. 2019 Mar;24(2):295-308. doi: 10.1007/s12192-019-00979-z. Epub 2019 Feb 13.


Bio-Molecular Applications of Recent Developments in Optical Tweezers.

Choudhary D, Mossa A, Jadhav M, Cecconi C.

Biomolecules. 2019 Jan 11;9(1). pii: E23. doi: 10.3390/biom9010023. Review.


The Complex Conformational Dynamics of Neuronal Calcium Sensor-1: A Single Molecule Perspective.

Choudhary D, Kragelund BB, Heidarsson PO, Cecconi C.

Front Mol Neurosci. 2018 Dec 17;11:468. doi: 10.3389/fnmol.2018.00468. eCollection 2018. Review.


Mechanical Folding and Unfolding of Protein Barnase at the Single-Molecule Level.

Alemany A, Rey-Serra B, Frutos S, Cecconi C, Ritort F.

Biophys J. 2016 Jan 5;110(1):63-74. doi: 10.1016/j.bpj.2015.11.015.


A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.

Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V.

EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357.


Single-molecule folding mechanisms of the apo- and Mg(2+)-bound states of human neuronal calcium sensor-1.

Naqvi MM, Heidarsson PO, Otazo MR, Mossa A, Kragelund BB, Cecconi C.

Biophys J. 2015 Jul 7;109(1):113-23. doi: 10.1016/j.bpj.2015.05.028.


The complex folding behavior of HIV-1-protease monomer revealed by optical-tweezer single-molecule experiments and molecular dynamics simulations.

Caldarini M, Sonar P, Valpapuram I, Tavella D, Volonté C, Pandini V, Vanoni MA, Aliverti A, Broglia RA, Tiana G, Cecconi C.

Biophys Chem. 2014 Dec;195:32-42. doi: 10.1016/j.bpc.2014.08.001. Epub 2014 Aug 14.


Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1.

Heidarsson PO, Naqvi MM, Otazo MR, Mossa A, Kragelund BB, Cecconi C.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13069-74. doi: 10.1073/pnas.1401065111. Epub 2014 Aug 25.


Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.

Mangione PP, Esposito G, Relini A, Raimondi S, Porcari R, Giorgetti S, Corazza A, Fogolari F, Penco A, Goto Y, Lee YH, Yagi H, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Chiti F, Rolandi R, Taylor GW, Pepys MB, Stoppini M, Bellotti V.

J Biol Chem. 2013 Oct 25;288(43):30917-30. doi: 10.1074/jbc.M113.498857. Epub 2013 Sep 6.


Single-molecule folding mechanism of an EF-hand neuronal calcium sensor.

Heidarsson PO, Otazo MR, Bellucci L, Mossa A, Imparato A, Paci E, Corni S, Di Felice R, Kragelund BB, Cecconi C.

Structure. 2013 Oct 8;21(10):1812-21. doi: 10.1016/j.str.2013.07.022. Epub 2013 Sep 5.


Conformational dynamics of single protein molecules studied by direct mechanical manipulation.

Heidarsson PO, Naqvi MM, Sonar P, Valpapuram I, Cecconi C.

Adv Protein Chem Struct Biol. 2013;92:93-133. doi: 10.1016/B978-0-12-411636-8.00003-1.


A highly compliant protein native state with a spontaneous-like mechanical unfolding pathway.

Heidarsson PO, Valpapuram I, Camilloni C, Imparato A, Tiana G, Poulsen FM, Kragelund BB, Cecconi C.

J Am Chem Soc. 2012 Oct 17;134(41):17068-75. doi: 10.1021/ja305862m. Epub 2012 Oct 4.


DNA molecular handles for single-molecule protein-folding studies by optical tweezers.

Cecconi C, Shank EA, Marqusee S, Bustamante C.

Methods Mol Biol. 2011;749:255-71. doi: 10.1007/978-1-61779-142-0_18.


The folding cooperativity of a protein is controlled by its chain topology.

Shank EA, Cecconi C, Dill JW, Marqusee S, Bustamante C.

Nature. 2010 Jun 3;465(7298):637-40. doi: 10.1038/nature09021. Epub 2010 May 23.


Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers.

Cecconi C, Shank EA, Dahlquist FW, Marqusee S, Bustamante C.

Eur Biophys J. 2008 Jul;37(6):729-38. doi: 10.1007/s00249-007-0247-y. Epub 2008 Jan 9.


Analysis of P element transposase protein-DNA interactions during the early stages of transposition.

Tang M, Cecconi C, Bustamante C, Rio DC.

J Biol Chem. 2007 Sep 28;282(39):29002-12. Epub 2007 Jul 19.


Direct observation of the three-state folding of a single protein molecule.

Cecconi C, Shank EA, Bustamante C, Marqusee S.

Science. 2005 Sep 23;309(5743):2057-60.


Guanosine triphosphate acts as a cofactor to promote assembly of initial P-element transposase-DNA synaptic complexes.

Tang M, Cecconi C, Kim H, Bustamante C, Rio DC.

Genes Dev. 2005 Jun 15;19(12):1422-5.


Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme.

Yang G, Cecconi C, Baase WA, Vetter IR, Breyer WA, Haack JA, Matthews BW, Dahlquist FW, Bustamante C.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):139-44.


Axotomy affects density but not properties of potassium leak channels, in the leech AP neurons.

Simoni A, Pellegrini M, Cecconi C, Pellegrino M.

Brain Res. 1990 Jul 2;522(1):118-24.


Model instructional program for mainstreaming handicapped children.

Cecconi CM, Rothenberg SP.

Phys Ther. 1980 Aug;60(8):1022-5.


Concentration of fibronectin in plasma of tumor-bearing mice and synthesis by Ehrlich ascites tumor cells.

Zardi L, Cecconi C, Barbieri O, Carnemolla B, Picca M, Santi L.

Cancer Res. 1979 Sep;39(9):3774-9.


Influence of reading level difficulty on the disfluencies of normal children.

Cecconi CP, Hood SB, Tucker RK.

J Speech Hear Res. 1977 Sep;20(3):475-84.


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