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Items: 1 to 50 of 56

1.

Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer.

Zoni E, Astrologo L, Ng CKY, Piscuoglio S, Melsen J, Grosjean J, Klima I, Chen L, Snaar-Jagalska EB, Flanagan K, van der Pluijm G, Kloen P, Cecchini MG, Kruithof-de Julio M, Thalmann GN.

Mol Cancer Res. 2019 May;17(5):1049-1062. doi: 10.1158/1541-7786.MCR-18-1220. Epub 2019 Feb 11.

PMID:
30745464
2.

Osteolytic cancer cells induce vascular/axon guidance processes in the bone/bone marrow stroma.

Hensel J, Wetterwald A, Temanni R, Keller I, Riether C, van der Pluijm G, Cecchini MG, Thalmann GN.

Oncotarget. 2018 Jun 22;9(48):28877-28896. doi: 10.18632/oncotarget.25608. eCollection 2018 Jun 22.

3.

The BMP antagonist Noggin is produced by osteoblasts in response to the presence of prostate cancer cells.

AlShaibi HF, Ahmed F, Buckle C, Fowles ACM, Awlia J, Cecchini MG, Eaton CL.

Biotechnol Appl Biochem. 2018 May;65(3):407-418. doi: 10.1002/bab.1619. Epub 2017 Nov 2.

PMID:
28981962
4.

The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches.

Özdemir BC, Hensel J, Secondini C, Wetterwald A, Schwaninger R, Fleischmann A, Raffelsberger W, Poch O, Delorenzi M, Temanni R, Mills IG, van der Pluijm G, Thalmann GN, Cecchini MG.

PLoS One. 2014 Dec 8;9(12):e114530. doi: 10.1371/journal.pone.0114530. eCollection 2014.

5.

Characterization and clinical relevance of ALDHbright populations in prostate cancer.

Le Magnen C, Bubendorf L, Rentsch CA, Mengus C, Gsponer J, Zellweger T, Rieken M, Thalmann GN, Cecchini MG, Germann M, Bachmann A, Wyler S, Heberer M, Spagnoli GC.

Clin Cancer Res. 2013 Oct 1;19(19):5361-71. doi: 10.1158/1078-0432.CCR-12-2857. Epub 2013 Aug 22.

6.

Circulating fibronectin controls tumor growth.

von Au A, Vasel M, Kraft S, Sens C, Hackl N, Marx A, Stroebel P, Hennenlotter J, Todenhöfer T, Stenzl A, Schott S, Sinn HP, Wetterwald A, Bermejo JL, Cecchini MG, Nakchbandi IA.

Neoplasia. 2013 Aug;15(8):925-38.

7.

Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells.

Bichsel CA, Gobaa S, Kobel S, Secondini C, Thalmann GN, Cecchini MG, Lutolf MP.

Lab Chip. 2012 Jul 7;12(13):2313-6. doi: 10.1039/c2lc40130d. Epub 2012 May 8.

PMID:
22565166
8.

Occlusion of seminal vesicles increases sexual activity in a mouse model.

Birkhäuser FD, Schumacher C, Seiler R, de Meuron L, Zehnder P, Roth B, Wetterwald A, Thalmann GN, Cecchini MG, Studer UE.

Eur Urol. 2012 Nov;62(5):855-62. doi: 10.1016/j.eururo.2012.04.036. Epub 2012 Apr 19.

PMID:
22552215
9.

High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth.

Ruiz C, Oeggerli M, Germann M, Gluderer S, Stocker H, Andreozzi M, Thalmann GN, Cecchini MG, Zellweger T, Stürm S, Koivisto PA, Helin HJ, Gelmann EP, Glass AG, Gasser TC, Terracciano LM, Bachmann A, Wyler S, Bubendorf L, Rentsch CA.

Prostate. 2012 Nov;72(15):1678-87. doi: 10.1002/pros.22521. Epub 2012 Apr 2.

PMID:
22473923
10.

Stem-like cells with luminal progenitor phenotype survive castration in human prostate cancer.

Germann M, Wetterwald A, Guzmán-Ramirez N, van der Pluijm G, Culig Z, Cecchini MG, Williams ED, Thalmann GN.

Stem Cells. 2012 Jun;30(6):1076-86. doi: 10.1002/stem.1087.

11.

Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.

Hömig-Hölzel C, van Doorn R, Vogel C, Germann M, Cecchini MG, Verdegaal E, Peeper DS.

EMBO J. 2011 May 4;30(9):1753-65. doi: 10.1038/emboj.2011.95. Epub 2011 Mar 29.

12.

The role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasis.

Secondini C, Wetterwald A, Schwaninger R, Thalmann GN, Cecchini MG.

PLoS One. 2011 Jan 13;6(1):e16078. doi: 10.1371/journal.pone.0016078.

13.

High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer.

van den Hoogen C, van der Horst G, Cheung H, Buijs JT, Lippitt JM, Guzmán-Ramírez N, Hamdy FC, Eaton CL, Thalmann GN, Cecchini MG, Pelger RC, van der Pluijm G.

Cancer Res. 2010 Jun 15;70(12):5163-73. doi: 10.1158/0008-5472.CAN-09-3806. Epub 2010 Jun 1.

14.

In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue.

Guzmán-Ramírez N, Völler M, Wetterwald A, Germann M, Cross NA, Rentsch CA, Schalken J, Thalmann GN, Cecchini MG.

Prostate. 2009 Nov 1;69(15):1683-93. doi: 10.1002/pros.21018.

PMID:
19644960
15.

Loss of inhibition over master pathways of bone mass regulation results in osteosclerotic bone metastases in prostate cancer.

Rentsch CA, Cecchini MG, Thalmann GN.

Swiss Med Wkly. 2009 Apr 18;139(15-16):220-5. doi: smw-12284. Review.

16.

Agents used for chemoprevention of prostate cancer may influence PSA secretion independently of cell growth in the LNCaP model of human prostate cancer progression.

Peternac D, Klima I, Cecchini MG, Schwaninger R, Studer UE, Thalmann GN.

Prostate. 2008 Sep 1;68(12):1307-18. doi: 10.1002/pros.20795.

PMID:
18512728
17.

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer.

Buijs JT, Henriquez NV, van Overveld PG, van der Horst G, Que I, Schwaninger R, Rentsch C, Ten Dijke P, Cleton-Jansen AM, Driouch K, Lidereau R, Bachelier R, Vukicevic S, Clézardin P, Papapoulos SE, Cecchini MG, Löwik CW, van der Pluijm G.

Cancer Res. 2007 Sep 15;67(18):8742-51.

18.

BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.

Buijs JT, Rentsch CA, van der Horst G, van Overveld PG, Wetterwald A, Schwaninger R, Henriquez NV, Ten Dijke P, Borovecki F, Markwalder R, Thalmann GN, Papapoulos SE, Pelger RC, Vukicevic S, Cecchini MG, Löwik CW, van der Pluijm G.

Am J Pathol. 2007 Sep;171(3):1047-57.

19.

Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases.

Schwaninger R, Rentsch CA, Wetterwald A, van der Horst G, van Bezooijen RL, van der Pluijm G, Löwik CW, Ackermann K, Pyerin W, Hamdy FC, Thalmann GN, Cecchini MG.

Am J Pathol. 2007 Jan;170(1):160-75.

20.

Prostate specific antigen expression does not necessarily correlate with prostate cancer cell growth.

Peternac D, Klima I, Cecchini MG, Studer UE, Thalmann GN.

J Urol. 2006 Jul;176(1):354-60.

PMID:
16753443
21.

Tissue microarray analysis of hMSH2 expression predicts outcome in men with prostate cancer.

Prtilo A, Leach FS, Markwalder R, Kappeler A, Burkhard FC, Cecchini MG, Studer UE, Thalmann GN.

J Urol. 2005 Nov;174(5):1814-8; discussion 1818.

PMID:
16217293
22.

Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo.

van der Pluijm G, Que I, Sijmons B, Buijs JT, Löwik CW, Wetterwald A, Thalmann GN, Papapoulos SE, Cecchini MG.

Cancer Res. 2005 Sep 1;65(17):7682-90.

23.

Differential expression of TGFbeta-stimulated clone 22 in normal prostate and prostate cancer.

Rentsch CA, Cecchini MG, Schwaninger R, Germann M, Markwalder R, Heller M, van der Pluijm G, Thalmann GN, Wetterwald A.

Int J Cancer. 2006 Feb 15;118(4):899-906.

24.

Noninvasive real-time in vivo bioluminescent imaging of gene expression and of tumor progression and metastasis.

Lowik CW, Cecchini MG, Maggi A, van der Pluijm G.

Ernst Schering Res Found Workshop. 2005;(49):193-227. Review. No abstract available.

PMID:
15524218
25.

Electroporation enhances transfection efficiency in murine cutaneous wounds.

Byrnes CK, Malone RW, Akhter N, Nass PH, Wetterwald A, Cecchini MG, Duncan MD, Harmon JW.

Wound Repair Regen. 2004 Jul-Aug;12(4):397-403.

PMID:
15260804
26.

Potential role of pre-existing blood vessels for vascularization and mineralization of osteochondral grafts: an intravital microscopic study in mice.

Rothenfluh DA, Demhartner TJ, Fraitzl CR, Cecchini MG, Ganz R, Leunig M.

Acta Orthop Scand. 2004 Jun;75(3):359-65.

PMID:
15260432
27.

Cellular interactions in the tropism of prostate cancer to bone.

Sikes RA, Nicholson BE, Koeneman KS, Edlund NM, Bissonette EA, Bradley MJ, Thalmann GN, Cecchini MG, Pienta KJ, Chung LW.

Int J Cancer. 2004 Jul 1;110(4):497-503.

28.

Peptabodies as tools to test ligands isolated from phage-displayed peptide libraries.

Clément G, Bisoffi M, Finger AN, Wetterwald A, Thalmann GN, Cecchini MG.

J Immunol Methods. 2003 May 1;276(1-2):135-41.

PMID:
12738366
29.

Insulin-like growth factor binding protein-3 is overexpressed in endothelial cells of mouse breast tumor vessels.

Schmid MC, Bisoffi M, Wetterwald A, Gautschi E, Thalmann GN, Mitola S, Bussolino F, Cecchini MG.

Int J Cancer. 2003 Feb 20;103(5):577-86.

30.

Can the reverse transcriptase-polymerase chain reaction for prostate specific antigen and prostate specific membrane antigen improve staging and predict biochemical recurrence?

Adsan O, Cecchini MG, Bisoffi M, Wetterwald A, Klima I, Danuser HJ, Studer UE, Thalmann GN.

BJU Int. 2002 Oct;90(6):579-85.

31.

Scavenger receptor block as strategy for the identification of bone marrow homing phages by panning in vivo random peptide phage displayed libraries.

Finger AN, Bisoffi M, Wetterwald A, Gautschi E, Hohenfeld U, Klima I, Stadler BM, Mazzucchelli L, Thalmann GN, Cecchini MG.

J Immunol Methods. 2002 Jun 1;264(1-2):173-86.

PMID:
12191520
32.

Dissociation of angiogenesis and osteoclastogenesis during endochondral bone formation in neonatal mice.

Deckers MM, Van Beek ER, Van Der Pluijm G, Wetterwald A, Van Der Wee-Pals L, Cecchini MG, Papapoulos SE, Löwik CW.

J Bone Miner Res. 2002 Jun;17(6):998-1007.

33.

Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease.

Wetterwald A, van der Pluijm G, Que I, Sijmons B, Buijs J, Karperien M, Löwik CW, Gautschi E, Thalmann GN, Cecchini MG.

Am J Pathol. 2002 Mar;160(3):1143-53.

34.

Urinary Interleukin-8 and 18 predict the response of superficial bladder cancer to intravesical therapy with bacillus Calmette-Guerin.

Thalmann GN, Sermier A, Rentsch C, Möhrle K, Cecchini MG, Studer UE.

J Urol. 2000 Dec;164(6):2129-33.

PMID:
11061941
35.

A role for N-cadherin in the development of the differentiated osteoblastic phenotype.

Ferrari SL, Traianedes K, Thorne M, Lafage-Proust MH, Genever P, Cecchini MG, Behar V, Bisello A, Chorev M, Rosenblatt M, Suva LJ.

J Bone Miner Res. 2000 Feb;15(2):198-208.

36.

Ipriflavone inhibits bone resorption in intact and ovariectomized rats.

Cecchini MG, Fleisch H, Mühibauer RC.

Calcif Tissue Int. 1997;61 Suppl 1:S9-11.

PMID:
9263609
37.

Role of CSF-1 in bone and bone marrow development.

Cecchini MG, Hofstetter W, Halasy J, Wetterwald A, Felix R.

Mol Reprod Dev. 1997 Jan;46(1):75-83; discussion 83-4. Review.

PMID:
8981367
38.

Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes.

Wetterwald A, Hoffstetter W, Cecchini MG, Lanske B, Wagner C, Fleisch H, Atkinson M.

Bone. 1996 Feb;18(2):125-32.

PMID:
8833206
39.

Recent developments in the understanding of the pathophysiology of osteopetrosis.

Felix R, Hofstetter W, Cecchini MG.

Eur J Endocrinol. 1996 Feb;134(2):143-56. Review.

PMID:
8630510
40.

Synthesis of membrane- and matrix-bound colony-stimulating factor-1 by cultured osteoblasts.

Felix R, Halasy-Nagy J, Wetterwald A, Cecchini MG, Fleisch H, Hofstetter W.

J Cell Physiol. 1996 Feb;166(2):311-22.

PMID:
8591991
41.

Downregulation of colony-stimulating factor-1 (CSF-1) binding by CSF-1 in isolated osteoclasts.

Amano H, Hofstetter W, Cecchini MG, Fleisch H, Felix R.

Calcif Tissue Int. 1995 Nov;57(5):367-70.

PMID:
8564799
42.

Detection of transcripts and binding sites for colony-stimulating factor-1 during bone development.

Hofstetter W, Wetterwald A, Cecchini MG, Mueller C, Felix R.

Bone. 1995 Aug;17(2):145-51.

PMID:
8554922
43.

Cytokine production by calvariae of osteopetrotic mice.

Felix R, Genolet CL, Löwik C, Cecchini MG, Hofstetter W.

Bone. 1995 Jul;17(1):5-9.

PMID:
7577158
44.
45.

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling.

Grigoriadis AE, Wang ZQ, Cecchini MG, Hofstetter W, Felix R, Fleisch HA, Wagner EF.

Science. 1994 Oct 21;266(5184):443-8.

PMID:
7939685
46.

Role of colony-stimulating factor-1 in bone metabolism.

Felix R, Hofstetter W, Wetterwald A, Cecchini MG, Fleisch H.

J Cell Biochem. 1994 Jul;55(3):340-9. Review.

PMID:
7962166
47.

Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse.

Cecchini MG, Dominguez MG, Mocci S, Wetterwald A, Felix R, Fleisch H, Chisholm O, Hofstetter W, Pollard JW, Stanley ER.

Development. 1994 Jun;120(6):1357-72.

48.
49.

Effect of macrophage colony-stimulating factor on in vitro osteoclast generation and bone resorption.

Corboz VA, Cecchini MG, Felix R, Fleisch H, van der Pluijm G, Löwik CW.

Endocrinology. 1992 Jan;130(1):437-42.

PMID:
1727717

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