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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1976 1
1982 1
1983 3
1984 1
1985 5
1986 3
1987 6
1988 5
1989 9
1990 14
1991 15
1992 25
1993 22
1994 34
1995 40
1996 37
1997 28
1998 43
1999 32
2000 29
2001 24
2002 27
2003 24
2004 33
2005 39
2006 29
2007 26
2008 33
2009 34
2010 35
2011 29
2012 23
2013 31
2014 32
2015 54
2016 35
2017 41
2018 36
2019 34
2020 34
2021 48
2022 44
2023 40
2024 7

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1,062 results

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Page 1
CDR2 and CDR2L line blot performance in PCA-1/anti-Yo paraneoplastic autoimmunity.
Vorasoot N, Scharf M, Miske R, Thakolwiboon S, Dubey D, Mills JR, Pittock SJ, Zekeridou A, Ott A, McKeon A. Vorasoot N, et al. Front Immunol. 2023 Sep 29;14:1265797. doi: 10.3389/fimmu.2023.1265797. eCollection 2023. Front Immunol. 2023. PMID: 37841252 Free PMC article.
Single-modality CDR2 testing may produce false-positive results. We assessed the performance characteristics of the more recently purported major PCA-1/Yo antigen, CDR2-like (CDR2L), side by side with CDR2, in a line blot format. ...RESULTS: Group 1: Of 64 sa …
Single-modality CDR2 testing may produce false-positive results. We assessed the performance characteristics of the more recently pur …
Reprogramming Cdr2-Dependent Geometry-Based Cell Size Control in Fission Yeast.
Facchetti G, Knapp B, Flor-Parra I, Chang F, Howard M. Facchetti G, et al. Curr Biol. 2019 Jan 21;29(2):350-358.e4. doi: 10.1016/j.cub.2018.12.017. Epub 2019 Jan 10. Curr Biol. 2019. PMID: 30639107 Free PMC article.
To investigate how Cdr2 nodes may sense area, we derive a minimal mathematical model that incorporates the cytoplasmic kinase Ssp1 as a Cdr2 activator. The model predicts that a cdr2 mutant in an Ssp1 phosphorylation site (cdr2-T166A) [4] should form n …
To investigate how Cdr2 nodes may sense area, we derive a minimal mathematical model that incorporates the cytoplasmic kinase Ssp1 as …
Design principles of Cdr2 node patterns in fission yeast cells.
Opalko H, Geng S, Hall AR, Vavylonis D, Moseley JB. Opalko H, et al. Mol Biol Cell. 2023 Oct 1;34(11):br18. doi: 10.1091/mbc.E23-04-0135. Epub 2023 Aug 23. Mol Biol Cell. 2023. PMID: 37610834 Free PMC article.
Here, we combined experimental and modeling approaches to investigate pattern formation by the Pom1-Cdr2 system. We found that Cdr2 nodes accumulate near the nucleus, and Cdr2 undergoes nucleocytoplasmic shuttling when cortical anchoring is reduced. We genera …
Here, we combined experimental and modeling approaches to investigate pattern formation by the Pom1-Cdr2 system. We found that Cdr …
Design principles of Cdr2 node patterns in fission yeast cells.
Opalko H, Geng S, Hall AR, Vavylonis D, Moseley JB. Opalko H, et al. bioRxiv [Preprint]. 2023 Jul 21:2023.04.19.537536. doi: 10.1101/2023.04.19.537536. bioRxiv. 2023. PMID: 37131752 Free PMC article. Updated. Preprint.
Here, we combined experimental and modeling approaches to investigate pattern formation by the Pom1-Cdr2 system. We found that Cdr2 nodes accumulate near the nucleus, and Cdr2 undergoes nucleocytoplasmic shuttling when cortical anchoring is reduced. We genera …
Here, we combined experimental and modeling approaches to investigate pattern formation by the Pom1-Cdr2 system. We found that Cdr …
Arf6 anchors Cdr2 nodes at the cell cortex to control cell size at division.
Opalko HE, Miller KE, Kim HS, Vargas-Garcia CA, Singh A, Keogh MC, Moseley JB. Opalko HE, et al. J Cell Biol. 2022 Feb 7;221(2):e202109152. doi: 10.1083/jcb.202109152. Epub 2021 Dec 27. J Cell Biol. 2022. PMID: 34958661 Free PMC article.
Cdr2 node anchoring at the cell cortex is not fully understood. Through a genomic screen, we identified the conserved GTPase Arf6 as a component of Cdr2 signaling. ...In arf6delta mutants, Cdr2 nodes detached from the membrane and exhibited increased dynamics …
Cdr2 node anchoring at the cell cortex is not fully understood. Through a genomic screen, we identified the conserved GTPase Arf6 as …
Conserved motifs in T-cell receptor CDR1 and CDR2: implications for ligand and CD8 co-receptor binding.
Arden B. Arden B. Curr Opin Immunol. 1998 Feb;10(1):74-81. doi: 10.1016/s0952-7915(98)80035-6. Curr Opin Immunol. 1998. PMID: 9523115 Review.
The limited diversity shown by CDRs 1 and 2 contrasts with the extreme junctional CDR3 diversity. Furthermore, CDR2 alignments have revealed conservation of a positive net charge in V alpha subfamilies. A model has been proposed for a direct interaction of the lateral part …
The limited diversity shown by CDRs 1 and 2 contrasts with the extreme junctional CDR3 diversity. Furthermore, CDR2 alignments have r …
Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration.
Herdlevaer I, Kråkenes T, Schubert M, Vedeler CA. Herdlevaer I, et al. Ann Clin Transl Neurol. 2020 Nov;7(11):2231-2242. doi: 10.1002/acn3.51212. Epub 2020 Oct 3. Ann Clin Transl Neurol. 2020. PMID: 33009713 Free PMC article.
RESULTS: We confirmed the CDR2L specificity of Yo antibodies by mass spectrometry-based proteomics and found that CDR2L localized to the cytoplasm and CDR2 to the nucleus. CDR2L co-localized with the 40S ribosomal protein S6, while CDR2 co-localized with the nuclear …
RESULTS: We confirmed the CDR2L specificity of Yo antibodies by mass spectrometry-based proteomics and found that CDR2L localized to the cyt …
MicroRNA 452 regulates ASB8, NOL8, and CDR2 expression in colorectal cancer cells.
Mo JS, Chae SC. Mo JS, et al. Genes Genomics. 2021 Jan;43(1):33-41. doi: 10.1007/s13258-020-01016-5. Epub 2021 Jan 4. Genes Genomics. 2021. PMID: 33398662
Up-regulated MIR452 also down-regulated ASB8, NOL8, and CDR2 mRNA and protein levels in CRC cells. CDR2 protein expression was decreased in CRC tissues compared to adjacent non-tumor tissues. CONCLUSIONS: These results suggest that ASB8, NOL8, and CDR2 were t …
Up-regulated MIR452 also down-regulated ASB8, NOL8, and CDR2 mRNA and protein levels in CRC cells. CDR2 protein expression was …
CDR2 antigen and Yo antibodies.
Totland C, Aarskog NK, Eichler TW, Haugen M, Nøstbakken JK, Monstad SE, Salvesen HB, Mørk S, Haukanes BI, Vedeler CA. Totland C, et al. Cancer Immunol Immunother. 2011 Feb;60(2):283-9. doi: 10.1007/s00262-010-0943-9. Epub 2010 Nov 16. Cancer Immunol Immunother. 2011. PMID: 21080165 Free PMC article.
We studied if there was an association between Yo antibody production and differences in CDR2 cDNA sequence, mRNA or CDR2 expression in ovarian cancers. We found similar CDR2 cDNA sequence, mRNA and protein levels in primary ovarian cancers, with or without a …
We studied if there was an association between Yo antibody production and differences in CDR2 cDNA sequence, mRNA or CDR2 expr …
1,062 results