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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 4
1999 2
2000 6
2001 5
2002 8
2003 14
2004 18
2005 15
2006 23
2007 20
2008 30
2009 29
2010 34
2011 33
2012 23
2013 29
2014 24
2015 20
2016 27
2017 26
2018 17
2019 25
2020 24
2021 24
2022 29
2023 29
2024 8

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490 results

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Page 1
CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands.
Korbecki J, Grochans S, Gutowska I, Barczak K, Baranowska-Bosiacka I. Korbecki J, et al. Int J Mol Sci. 2020 Oct 15;21(20):7619. doi: 10.3390/ijms21207619. Int J Mol Sci. 2020. PMID: 33076281 Free PMC article. Review.
In this review, we discuss human CC motif chemokine ligands: CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CCL28 (CC motif chemokine receptor CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 ligands). We present their functioning in human physiology and in n …
In this review, we discuss human CC motif chemokine ligands: CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CCL28 (CC …
Roles of CCR10/CCL27-CCL28 axis in tumour development: mechanisms, diagnostic and therapeutic approaches, and perspectives.
Mergia Terefe E, Catalan Opulencia MJ, Rakhshani A, Ansari MJ, Sergeevna SE, Awadh SA, Polatova DS, Abdulkadhim AH, Mustafa YF, Kzar HH, Al-Gazally ME, Kadhim MM, Taherian G. Mergia Terefe E, et al. Expert Rev Mol Med. 2022 Sep 26;24:e37. doi: 10.1017/erm.2022.28. Expert Rev Mol Med. 2022. PMID: 36155126 Review.
Depending on the types of lymphocytes recruited, CCR10/CCL27-CCL28 interaction has been shown to play conflicting roles in cancer development. ...Since CCR10/CCL27-CCL28 is dysregulated in the tumour tissues, it is suggested that analysis and measurement of them mig …
Depending on the types of lymphocytes recruited, CCR10/CCL27-CCL28 interaction has been shown to play conflicting roles in cancer dev …
CCR10 and its ligands in regulation of epithelial immunity and diseases.
Xiong N, Fu Y, Hu S, Xia M, Yang J. Xiong N, et al. Protein Cell. 2012 Aug;3(8):571-80. doi: 10.1007/s13238-012-2927-3. Epub 2012 Jun 8. Protein Cell. 2012. PMID: 22684736 Free PMC article. Review.
Circulating T cells might be imprinted by skin-associated antigen- presenting cells to express CCR10 for their recruitment to the skin during the local immune response. ...Herein, we review current knowledge on roles of CCR10/ligands in regulation of epithelial immu …
Circulating T cells might be imprinted by skin-associated antigen- presenting cells to express CCR10 for their recruitment to the ski …
CCR10(+) ILC2s with ILC1-like properties exhibit a protective function in severe allergic asthma.
Beuraud C, Lombardi V, Luce S, Horiot S, Naline E, Neukirch C, Airouche S, Perchet T, Golub R, Devillier P, Chollet-Martin S, Baron-Bodo V, Nony E, Aubier M, Mascarell L, Moingeon P. Beuraud C, et al. Allergy. 2019 May;74(5):933-943. doi: 10.1111/all.13679. Epub 2018 Dec 28. Allergy. 2019. PMID: 30475388
Characteristics of human CCR10(+) and CCR10(-) ILC2s were assessed by flow cytometry as well as single-cell multiplex RT-qPCR. The role of CCR10(+) ILC2s in asthma pathophysiology was studied in allergen-treated mice. ...
Characteristics of human CCR10(+) and CCR10(-) ILC2s were assessed by flow cytometry as well as single-cell multiplex RT-qPCR. …
CCR10/CCL27 crosstalk regulates cell metastasis via PI3K-Akt signaling axis in non-small-cell lung cancer.
Liu Y, Xiao A, Zhang B. Liu Y, et al. Am J Transl Res. 2021 Nov 15;13(11):13135-13146. eCollection 2021. Am J Transl Res. 2021. PMID: 34956534 Free PMC article.
Previous research has shown that CCR10 acts as a vital oncogene in the progression of multiple malignancies. ...Further study showed that metastasis-relevant VEGF-C/D, MMP-2/9, TIMP-1/2 were also regulated via CCR10 activation. Notably, increased NF-kappaB levels we …
Previous research has shown that CCR10 acts as a vital oncogene in the progression of multiple malignancies. ...Further study showed …
Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF.
Hohmann MS, Habiel DM, Espindola MS, Huang G, Jones I, Narayanan R, Coelho AL, Oldham JM, Noth I, Ma SF, Kurkciyan A, McQualter JL, Carraro G, Stripp B, Chen P, Jiang D, Noble PW, Parks W, Woronicz J, Yarranton G, Murray LA, Hogaboam CM. Hohmann MS, et al. JCI Insight. 2021 Jun 8;6(11):e141061. doi: 10.1172/jci.insight.141061. JCI Insight. 2021. PMID: 33945505 Free PMC article.
In vitro, CCL28 promoted the proliferation of CCR10+ MPCs while CRISPR/Cas9-mediated targeting of CCR10 resulted in the death of MPCs. ...Thus, human CCR10+ cells promote pulmonary fibrosis, and EphA3 mAb-directed elimination of these cells inhibits lung fibr …
In vitro, CCL28 promoted the proliferation of CCR10+ MPCs while CRISPR/Cas9-mediated targeting of CCR10 resulted in the death …
[Role of the CCL28-CCR10 pathway in monocyte migration in rheumatoid arthritis].
Cheng F, Yang SY, Fang XX, Wang X, Zhao FT. Cheng F, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Dec 18;54(6):1074-1078. doi: 10.19723/j.issn.1671-167X.2022.06.003. Beijing Da Xue Xue Bao Yi Xue Ban. 2022. PMID: 36533335 Free PMC article. Chinese.
OBJECTIVE: To examine the expression of chemokine receptor CCR10 on monocytes/macrophages in the joints of patients with rheumatoid arthritis (RA), and to investigate the role of chemokine CCL28 and its receptor CCR10 in the migration of RA monocytes and its mechani …
OBJECTIVE: To examine the expression of chemokine receptor CCR10 on monocytes/macrophages in the joints of patients with rheumatoid a …
CCL28-induced CCR10/eNOS interaction in angiogenesis and skin wound healing.
Chen Z, Haus JM, Chen L, Wu SC, Urao N, Koh TJ, Minshall RD. Chen Z, et al. FASEB J. 2020 Apr;34(4):5838-5850. doi: 10.1096/fj.201902060R. Epub 2020 Mar 2. FASEB J. 2020. PMID: 32124475 Free PMC article.
We observed nitric oxide (NO) production in human primary ECs stimulated with exogenous CCL28, which also induced direct binding of CCR10 and eNOS resulting in inhibition of eNOS activity. Knockdown of CCR10 with siRNA lead to reduced eNOS expression and tube format …
We observed nitric oxide (NO) production in human primary ECs stimulated with exogenous CCL28, which also induced direct binding of CCR10
Blocking CCR10 Expression Activates m6A Methylation and Alleviates Vascular Endothelial Cell Injury.
Zhou Z, Yang H, Wang X, Yi L. Zhou Z, et al. Discov Med. 2023 Feb 1;35(174):36-44. doi: 10.24976/Discov.Med.202335174.5. Discov Med. 2023. PMID: 37024440
RESULTS: In this study, 20 DEGs were screened out from the two groups by RNA-Seq, of which 17 were up-regulated and 3 were down-regulated. The C-C motif chemokine receptor 10 (CCR10) was selected for subsequent analysis. Real-Time Quantitative Reverse Transcription Polymer …
RESULTS: In this study, 20 DEGs were screened out from the two groups by RNA-Seq, of which 17 were up-regulated and 3 were down-regulated. T …
Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer.
Chen Z, Zhang G, Ren X, Yao Z, Zhou Q, Ren X, Chen S, Xu L, Sun K, Zeng Q, Kuang M, Kuang DM, Peng S. Chen Z, et al. Cancer Res. 2023 Nov 1;83(21):3544-3561. doi: 10.1158/0008-5472.CAN-23-0193. Cancer Res. 2023. PMID: 37352379
Mechanistically, IgG+ plasma cells in HCC were recruited by tumor-associated macrophages via the CXCR3-CXCL10 axis, whereas IgA+ plasma cells in CRLM were recruited by metastatic tumor cells via CCR10-CCL28 signaling. Functionally, IgG+ plasma cells preferentially promoted …
Mechanistically, IgG+ plasma cells in HCC were recruited by tumor-associated macrophages via the CXCR3-CXCL10 axis, whereas IgA+ plasma cell …
490 results