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Items: 30


The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs.

Bivona AE, Czentner L, Sanchez Alberti A, Cerny N, Cardoso Landaburu AC, Nevot C, Estévez O, Marco JD, Basombrio MA, Malchiodi EL, Cazorla SI.

J Clin Microbiol. 2019 Aug 21. pii: JCM.00819-19. doi: 10.1128/JCM.00819-19. [Epub ahead of print]


Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis.

Sülsen VP, Lizarraga EF, Elso OG, Cerny N, Sanchez Alberti A, Bivona AE, Malchiodi EL, Cazorla SI, Catalán CAN.

Molecules. 2019 Mar 28;24(7). pii: E1209. doi: 10.3390/molecules24071209.


Beneficial Effects of Probiotic Consumption on the Immune System.

Maldonado Galdeano C, Cazorla SI, Lemme Dumit JM, Vélez E, Perdigón G.

Ann Nutr Metab. 2019;74(2):115-124. doi: 10.1159/000496426. Epub 2019 Jan 23. Review.


Oral Administration of Probiotics Increases Paneth Cells and Intestinal Antimicrobial Activity.

Cazorla SI, Maldonado-Galdeano C, Weill R, De Paula J, Perdigón GDV.

Front Microbiol. 2018 Apr 16;9:736. doi: 10.3389/fmicb.2018.00736. eCollection 2018.


Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine.

Bivona AE, Sánchez Alberti A, Matos MN, Cerny N, Cardoso AC, Morales C, González G, Cazorla SI, Malchiodi EL.

PLoS Negl Trop Dis. 2018 Mar 30;12(3):e0006384. doi: 10.1371/journal.pntd.0006384. eCollection 2018 Mar.


Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection.

Sanchez Alberti A, Bivona AE, Cerny N, Schulze K, Weißmann S, Ebensen T, Morales C, Padilla AM, Cazorla SI, Tarleton RL, Guzmán CA, Malchiodi EL.

NPJ Vaccines. 2017 Apr 10;2:9. doi: 10.1038/s41541-017-0010-z. eCollection 2017.


Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Laurella LC, Cerny N, Bivona AE, Sánchez Alberti A, Giberti G, Malchiodi EL, Martino VS, Catalan CA, Alonso MR, Cazorla SI, Sülsen VP.

PLoS Negl Trop Dis. 2017 Sep 25;11(9):e0005929. doi: 10.1371/journal.pntd.0005929. eCollection 2017 Sep.


Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi.

Matos MN, Cazorla SI, Schulze K, Ebensen T, Guzmán CA, Malchiodi EL.

PLoS Negl Trop Dis. 2017 Feb 24;11(2):e0005300. doi: 10.1371/journal.pntd.0005300. eCollection 2017 Feb.


A prime-boost immunization with Tc52 N-terminal domain DNA and the recombinant protein expressed in Pichia pastoris protects against Trypanosoma cruzi infection.

Matos MN, Sánchez Alberti A, Morales C, Cazorla SI, Malchiodi EL.

Vaccine. 2016 Jun 14;34(28):3243-51. doi: 10.1016/j.vaccine.2016.05.011. Epub 2016 May 10.


Attenuated Salmonella sp. as a DNA Delivery System for Trypanosoma cruzi Antigens.

Bivona AE, Cerny N, Alberti AS, Cazorla SI, Malchiodi EL.

Methods Mol Biol. 2016;1404:683-95. doi: 10.1007/978-1-4939-3389-1_44.


Trypanocidal and leishmanicidal activities of flavonoids isolated from Stevia satureiifolia var. satureiifolia.

Beer MF, Frank FM, Germán Elso O, Ernesto Bivona A, Cerny N, Giberti G, Luis Malchiodi E, Susana Martino V, Alonso MR, Patricia Sülsen V, Cazorla SI.

Pharm Biol. 2016 Oct;54(10):2188-95. doi: 10.3109/13880209.2016.1150304. Epub 2016 Mar 17.


Coadministration of cruzipain and GM-CSF DNAs, a new immunotherapeutic vaccine against Trypanosoma cruzi infection.

Cerny N, Sánchez Alberti A, Bivona AE, De Marzi MC, Frank FM, Cazorla SI, Malchiodi EL.

Hum Vaccin Immunother. 2016;12(2):438-50. doi: 10.1080/21645515.2015.1078044.


Oral multicomponent DNA vaccine delivered by attenuated Salmonella elicited immunoprotection against American trypanosomiasis.

Cazorla SI, Matos MN, Cerny N, Ramirez C, Alberti AS, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

J Infect Dis. 2015 Mar 1;211(5):698-707. doi: 10.1093/infdis/jiu480. Epub 2014 Aug 25.


Tc52 amino-terminal-domain DNA carried by attenuated Salmonella enterica serovar Typhimurium induces protection against a Trypanosoma cruzi lethal challenge.

Matos MN, Cazorla SI, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

Infect Immun. 2014 Oct;82(10):4265-75. doi: 10.1128/IAI.02190-14. Epub 2014 Jul 28.


Natural terpenoids from Ambrosia species are active in vitro and in vivo against human pathogenic trypanosomatids.

Sülsen VP, Cazorla SI, Frank FM, Laurella LC, Muschietti LV, Catalán CA, Martino VS, Malchiodi EL.

PLoS Negl Trop Dis. 2013 Oct 10;7(10):e2494. doi: 10.1371/journal.pntd.0002494. eCollection 2013.


Trypanocidal Activity of Smallanthus sonchifolius: Identification of Active Sesquiterpene Lactones by Bioassay-Guided Fractionation.

Frank FM, Ulloa J, Cazorla SI, Maravilla G, Malchiodi EL, Grau A, Martino V, Catalán C, Muschietti LV.

Evid Based Complement Alternat Med. 2013;2013:627898. doi: 10.1155/2013/627898. Epub 2013 Jun 6.


An improved DNA isolation technique for PCR detection of Strongyloides stercoralis in stool samples.

Repetto SA, Alba Soto CD, Cazorla SI, Tayeldin ML, Cuello S, Lasala MB, Tekiel VS, González Cappa SM.

Acta Trop. 2013 May;126(2):110-4. doi: 10.1016/j.actatropica.2013.02.003. Epub 2013 Feb 12.


Trypanosoma cruzi, the causative agent of Chagas disease, modulates interleukin-6-induced STAT3 phosphorylation via gp130 cleavage in different host cells.

Ponce NE, Carrera-Silva EA, Pellegrini AV, Cazorla SI, Malchiodi EL, Lima AP, Gea S, Aoki MP.

Biochim Biophys Acta. 2013 Mar;1832(3):485-94. doi: 10.1016/j.bbadis.2012.12.003. Epub 2012 Dec 16.


In vitro evaluation of antiprotozoal and antiviral activities of extracts from Argentinean Mikania species.

Laurella LC, Frank FM, Sarquiz A, Alonso MR, Giberti G, Cavallaro L, Catalán CA, Cazorla SI, Malchiodi E, Martino VS, Sülsen VP.

ScientificWorldJournal. 2012;2012:121253. doi: 10.1100/2012/121253. Epub 2012 Jul 31.


Synthesis, trypanocidal activity and molecular modeling studies of 2-alkylaminomethylquinoline derivatives.

Muscia GC, Cazorla SI, Frank FM, Borosky GL, Buldain GY, Asís SE, Malchiodi EL.

Eur J Med Chem. 2011 Sep;46(9):3696-703. doi: 10.1016/j.ejmech.2011.05.035. Epub 2011 May 20.


Psilostachyin C: a natural compound with trypanocidal activity.

Sülsen VP, Frank FM, Cazorla SI, Barrera P, Freixa B, Vila R, Sosa MA, Malchiodi EL, Muschietti LV, Martino VS.

Int J Antimicrob Agents. 2011 Jun;37(6):536-43. doi: 10.1016/j.ijantimicag.2011.02.003. Epub 2011 Apr 15.


Redirection of the immune response to the functional catalytic domain of the cystein proteinase cruzipain improves protective immunity against Trypanosoma cruzi infection.

Cazorla SI, Frank FM, Becker PD, Arnaiz M, Mirkin GA, Corral RS, Guzmán CA, Malchiodi EL.

J Infect Dis. 2010 Jul 1;202(1):136-44. doi: 10.1086/652872.


Inhibition of HIV-1 replication in human monocyte-derived macrophages by parasite Trypanosoma cruzi.

Andreani G, Celentano AM, Solana ME, Cazorla SI, Malchiodi EL, Martínez Peralta LA, Dolcini GL.

PLoS One. 2009 Dec 14;4(12):e8246. doi: 10.1371/journal.pone.0008246.


Vaccination approaches against Trypanosoma cruzi infection.

Cazorla SI, Frank FM, Malchiodi EL.

Expert Rev Vaccines. 2009 Jul;8(7):921-35. doi: 10.1586/erv.09.45. Review.


Trypanocidal and leishmanicidal activities of sesquiterpene lactones from Ambrosia tenuifolia Sprengel (Asteraceae).

Sülsen VP, Frank FM, Cazorla SI, Anesini CA, Malchiodi EL, Freixa B, Vila R, Muschietti LV, Martino VS.

Antimicrob Agents Chemother. 2008 Jul;52(7):2415-9. doi: 10.1128/AAC.01630-07. Epub 2008 Apr 28.


Prime-boost immunization with cruzipain co-administered with MALP-2 triggers a protective immune response able to decrease parasite burden and tissue injury in an experimental Trypanosoma cruzi infection model.

Cazorla SI, Frank FM, Becker PD, Corral RS, Guzmán CA, Malchiodi EL.

Vaccine. 2008 Apr 7;26(16):1999-2009. doi: 10.1016/j.vaccine.2008.02.011. Epub 2008 Feb 22.


Elicitation of specific, Th1-biased immune response precludes skeletal muscle damage in cruzipain-vaccinated mice.

Frank FM, Cazorla SI, Sartori MJ, Corral RS.

Exp Mol Pathol. 2008 Feb;84(1):64-70. Epub 2007 Nov 7.


Trypanocidal and leishmanicidal activities of flavonoids from Argentine medicinal plants.

Sülsen VP, Cazorla SI, Frank FM, Redko FC, Anesini CA, Coussio JD, Malchiodi EL, Martino VS, Muschietti LV.

Am J Trop Med Hyg. 2007 Oct;77(4):654-9.


Oral vaccination with Salmonella enterica as a cruzipain-DNA delivery system confers protective immunity against Trypanosoma cruzi.

Cazorla SI, Becker PD, Frank FM, Ebensen T, Sartori MJ, Corral RS, Malchiodi EL, Guzmán CA.

Infect Immun. 2008 Jan;76(1):324-33. Epub 2007 Oct 29.


Use of a purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides for immunoprotection against a lethal challenge with trypomastigotes.

Frank FM, Petray PB, Cazorla SI, Muñoz MC, Corral RS, Malchiodi EL.

Vaccine. 2003 Dec 8;22(1):77-86.


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