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Establishing a mentorship program in rural workplaces: connection, communication, and support required.

Rohatinsky N, Cave J, Krauter C.

Rural Remote Health. 2020 Jan;20(1):5640. doi: 10.22605/RRH5640. Epub 2020 Jan 13.


Polypharmacy and deprescribing: just ask the patient.

Cave JA.

Drug Ther Bull. 2020 Jan;58(1):2. doi: 10.1136/dtb.2019.000083. Epub 2019 Nov 14. No abstract available.


Omics Forecasting: Predictive Calculations Permit the Rapid Interpretation of High-Resolution Mass Spectral Data from Complex Mixtures.

Cave JR, Parker E, Lebrilla C, Waterhouse AL.

J Agric Food Chem. 2019 Dec 4;67(48):13318-13326. doi: 10.1021/acs.jafc.9b04384. Epub 2019 Nov 20.


Meeting QOF hypertension targets but failing the patient.

Cave JA.

Drug Ther Bull. 2019 Nov;57(11):162. doi: 10.1136/dtb.2019.000048. Epub 2019 Sep 4. No abstract available.


The utility of Ki-67 as a prognostic biomarker in pulmonary neuroendocrine tumours: protocol for a systematic review and meta-analysis.

Naheed S, Holden C, Tanno L, Jaynes E, Cave J, Ottensmeier CH, Pelosi G.

BMJ Open. 2019 Aug 24;9(8):e031531. doi: 10.1136/bmjopen-2019-031531.


Non-typhoidal salmonellosis presenting as acute calculus cholecystitis.

Juma F, Cave JJ, Gonzales H, Moore LSP.

BMJ Case Rep. 2019 Jul 19;12(7). pii: e230186. doi: 10.1136/bcr-2019-230186.


Combinatorics of proanthocyanidins in wine.

Cave JR, Waterhouse AL.

Analyst. 2019 Jul 8;144(14):4395-4399. doi: 10.1039/c9an00439d.


Patient Preference Studies During Early Drug Development: Aligning Stakeholders to Ensure Development Plans Meet Patient Needs.

Cook NS, Cave J, Holtorf AP.

Front Med (Lausanne). 2019 Apr 24;6:82. doi: 10.3389/fmed.2019.00082. eCollection 2019.


Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke.

Alim I, Caulfield JT, Chen Y, Swarup V, Geschwind DH, Ivanova E, Seravalli J, Ai Y, Sansing LH, Ste Marie EJ, Hondal RJ, Mukherjee S, Cave JW, Sagdullaev BT, Karuppagounder SS, Ratan RR.

Cell. 2019 May 16;177(5):1262-1279.e25. doi: 10.1016/j.cell.2019.03.032. Epub 2019 May 2.


The new GP contract: an opportunity for drugs and therapeutics.

Cave J.

Drug Ther Bull. 2019 May;57(5):66. doi: 10.1136/dtb.2019.000020. No abstract available.


The Impact of Price Reductions After Loss of Exclusivity in a Cost-Effectiveness Analysis: Fingolimod Versus Interferon Beta-1a for the Treatment of Relapsing-Remitting Multiple Sclerosis.

Hua LH, Hersh CM, Morten P, Kusel J, Lin F, Cave J, Varga S, Herrera V, Ko JJ.

J Manag Care Spec Pharm. 2019 Apr;25(4):490-498. doi: 10.18553/jmcp.2019.25.4.490.


Recent advances in the molecular landscape of lung neuroendocrine tumors.

Pelosi G, Bianchi F, Hofman P, Pattini L, Ströbel P, Calabrese F, Naheed S, Holden C, Cave J, Bohnenberger H, Dinter H, Harari S, Albini A, Sonzogni A, Papotti M, Volante M, Ottensmeier CH.

Expert Rev Mol Diagn. 2019 Apr;19(4):281-297. doi: 10.1080/14737159.2019.1595593. Epub 2019 Mar 27.


A new DiRECTion for diabetes.

Cave J, Phizackerley D.

Drug Ther Bull. 2019 Mar;57(3):34. doi: 10.1136/dtb.2019.000007. No abstract available.


Exercise prehabilitation may lead to augmented tumor regression following neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

West MA, Astin R, Moyses HE, Cave J, White D, Levett DZH, Bates A, Brown G, Grocott MPW, Jack S.

Acta Oncol. 2019 May;58(5):588-595. doi: 10.1080/0284186X.2019.1566775. Epub 2019 Feb 6.


Paramedics: what can we expect.

Cave J.

J R Soc Med. 2018 Nov;111(11):388-389. doi: 10.1177/0141076818789050. No abstract available.


Restrictions on travelling with medicines.

Cave J.

Drug Ther Bull. 2018 Nov;56(11):132-135. doi: 10.1136/dtb.2018.11.000012. Review. No abstract available.


Progress in the development of olfactory-based bioelectronic chemosensors.

Cave JW, Wickiser JK, Mitropoulos AN.

Biosens Bioelectron. 2019 Jan 1;123:211-222. doi: 10.1016/j.bios.2018.08.063. Epub 2018 Aug 27. Review.


Paediatric robotic surgery.

Cave J, Clarke S.

Ann R Coll Surg Engl. 2018 Sep;100(Suppl 7):18-21. doi: 10.1308/rcsann.supp2.18. Review.


What's in a name?

Cave J.

Drug Ther Bull. 2018 Sep;56(9):98. doi: 10.1136/dtb.2018.9.000017. Epub 2018 Aug 27. No abstract available.


A systematic review of the safety and efficacy of aerobic exercise during cytotoxic chemotherapy treatment.

Cave J, Paschalis A, Huang CY, West M, Copson E, Jack S, Grocott MPW.

Support Care Cancer. 2018 Oct;26(10):3337-3351. doi: 10.1007/s00520-018-4295-x. Epub 2018 Jun 24.


The role of digital communication in patient–clinician communication for NHS providers of specialist clinical services for young people [the Long-term conditions Young people Networked Communication (LYNC) study]: a mixed-methods study.

Griffiths FE, Armoiry X, Atherton H, Bryce C, Buckle A, Cave JAK, Court R, Hamilton K, Dliwayo TR, Dritsaki M, Elder P, Forjaz V, Fraser J, Goodwin R, Huxley C, Ignatowicz A, Karasouli E, Kim SW, Kimani P, Madan JJ, Matharu H, May M, Musumadi L, Paul M, Raut G, Sankaranarayanan S, Slowther AM, Sujan MA, Sutcliffe PA, Svahnstrom I, Taggart F, Uddin A, Verran A, Walker L, Sturt J.

Southampton (UK): NIHR Journals Library; 2018 Feb.


BDNF activates an NFI-dependent neurodevelopmental timing program by sequestering NFATc4.

Ding B, Dobner PR, Mullikin-Kilpatrick D, Wang W, Zhu H, Chow CW, Cave JW, Gronostajski RM, Kilpatrick DL.

Mol Biol Cell. 2018 Apr 15;29(8):975-987. doi: 10.1091/mbc.E16-08-0595. Epub 2018 Mar 30.


Proactive multi-modality treatment of Pancreatic Neuroendocrine Tumours (PNETs): Potential survival benefits.

Tanno L, Mayo D, Mills S, Takhar A, Cave J, Nolan L, Stedman B, Sundram FX, Abu Hilal M, Connor H, Pearce N, Armstrong T.

Pancreatology. 2018 Apr;18(3):304-312. doi: 10.1016/j.pan.2017.12.006. Epub 2017 Dec 14.


Conserved Upstream Regulatory Regions in Mammalian Tyrosine Hydroxylase.

Wang M, Fones L, Cave JW.

Mol Neurobiol. 2018 Sep;55(9):7340-7351. doi: 10.1007/s12035-018-0936-9. Epub 2018 Feb 5.


Tumour diameter is not reliable for management of non-secreting pancreatic neuroendocrine tumours.

Mills L, Drymousis P, Vashist Y, Burdelski C, Prachalias A, Srinivasan P, Menon K, Cotoi C, Khan S, Cave J, Armstrong T, Weickert MO, Izbicki J, Schrader J, Frilling A, Ramage JK, Srirajaskanthan R.

Endocr Connect. 2017 Nov;6(8):876-885. doi: 10.1530/EC-17-0293.


Towards personalised medicine in lung and thymus neuroendocrine tumours.

Pelosi G, Cave J, Ottensmeier CH.

Lancet Oncol. 2017 Dec;18(12):1563-1565. doi: 10.1016/S1470-2045(17)30784-2. Epub 2017 Oct 23. No abstract available.


Clinically Significant Differences in Ki-67 Proliferation Index Between Primary and Metastases in Resected Pancreatic Neuroendocrine Tumors.

Richards-Taylor S, Tilley C, Jaynes E, Hu H, Armstrong T, Pearce NW, Plant R, Cave J.

Pancreas. 2017 Nov/Dec;46(10):1354-1358. doi: 10.1097/MPA.0000000000000933.


Cytoarchitectural changes in the olfactory bulb of Parkinson's disease patients.

Cave JW, Fujiwara N, Weibman AR, Baker H.

NPJ Parkinsons Dis. 2016 Jun 9;2:16011. doi: 10.1038/npjparkd.2016.11. eCollection 2016.


Odorant Sensory Input Modulates DNA Secondary Structure Formation and Heterogeneous Ribonucleoprotein Recruitment on the Tyrosine Hydroxylase and Glutamic Acid Decarboxylase 1 Promoters in the Olfactory Bulb.

Wang M, Cai E, Fujiwara N, Fones L, Brown E, Yanagawa Y, Cave JW.

J Neurosci. 2017 May 3;37(18):4778-4789. doi: 10.1523/JNEUROSCI.1363-16.2017. Epub 2017 Apr 14.


Timely Digital Patient-Clinician Communication in Specialist Clinical Services for Young People: A Mixed-Methods Study (The LYNC Study).

Griffiths F, Bryce C, Cave J, Dritsaki M, Fraser J, Hamilton K, Huxley C, Ignatowicz A, Kim SW, Kimani PK, Madan J, Slowther AM, Sujan M, Sturt J.

J Med Internet Res. 2017 Apr 10;19(4):e102. doi: 10.2196/jmir.7154.


Should gluten-free foods be available on prescription?

Kurien M, Sleet S, Sanders DS, Cave J.

BMJ. 2017 Jan 10;356:i6810. doi: 10.1136/bmj.i6810. No abstract available.


Partial Conservation between Mice and Humans in Olfactory Bulb Interneuron Transcription Factor Codes.

Fujiwara N, Cave JW.

Front Neurosci. 2016 Jul 20;10:337. doi: 10.3389/fnins.2016.00337. eCollection 2016.


Utilizing Energy Transfer in Binary and Ternary Bulk Heterojunction Organic Solar Cells.

Feron K, Cave JM, Thameel MN, O'Sullivan C, Kroon R, Andersson MR, Zhou X, Fell CJ, Belcher WJ, Walker AB, Dastoor PC.

ACS Appl Mater Interfaces. 2016 Aug 17;8(32):20928-37. doi: 10.1021/acsami.6b05474. Epub 2016 Aug 4.


Oncology and medical education-past, present and future.

Cave J.

Ecancermedicalscience. 2016 May 16;10:ed54. doi: 10.3332/ecancer.2016.ed54. eCollection 2016.


Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC.

Arriola E, Wheater M, Galea I, Cross N, Maishman T, Hamid D, Stanton L, Cave J, Geldart T, Mulatero C, Potter V, Danson S, Woll PJ, Griffiths R, Nolan L, Ottensmeier C.

J Thorac Oncol. 2016 Sep;11(9):1511-21. doi: 10.1016/j.jtho.2016.05.028. Epub 2016 Jun 11.


Nature and nurture meet at the epigenome to modulate disorders of the nervous system.

Cave JW, Langley B, Ratan RR.

Neurosci Lett. 2016 Jun 20;625:1-3. doi: 10.1016/j.neulet.2016.05.052. No abstract available.


The Impact of Online Social Networks on Health and Health Systems: A Scoping Review and Case Studies.

Griffiths F, Dobermann T, Cave JA, Thorogood M, Johnson S, Salamatian K, Gomez Olive FX, Goudge J.

Policy Internet. 2015 Dec;7(4):473-496. Epub 2015 Sep 1.


The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.

Waisbourd-Zinman O, Koh H, Tsai S, Lavrut PM, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG.

Hepatology. 2016 Sep;64(3):880-93. doi: 10.1002/hep.28599. Epub 2016 May 20.


Reciprocal autoregulation by NFI occupancy and ETV1 promotes the developmental expression of dendrite-synapse genes in cerebellar granule neurons.

Ding B, Cave JW, Dobner PR, Mullikin-Kilpatrick D, Bartzokis M, Zhu H, Chow CW, Gronostajski RM, Kilpatrick DL.

Mol Biol Cell. 2016 May 1;27(9):1488-99. doi: 10.1091/mbc.E15-07-0476. Epub 2016 Mar 3.


Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.

Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR.

Sci Transl Med. 2016 Mar 2;8(328):328ra29. doi: 10.1126/scitranslmed.aac6008.


The ethics of data and of data science: an economist's perspective.

Cave J.

Philos Trans A Math Phys Eng Sci. 2016 Dec 28;374(2083). pii: 20160117. doi: 10.1098/rsta.2016.0117. Review.


The assessment of Ki-67 as a prognostic marker in neuroendocrine tumours: a systematic review and meta-analysis.

Richards-Taylor S, Ewings SM, Jaynes E, Tilley C, Ellis SG, Armstrong T, Pearce N, Cave J.

J Clin Pathol. 2016 Jul;69(7):612-8. doi: 10.1136/jclinpath-2015-203340. Epub 2015 Dec 17. Review.


Selective repression of gene expression in neuropathic pain by the neuron-restrictive silencing factor/repressor element-1 silencing transcription (NRSF/REST).

Willis DE, Wang M, Brown E, Fones L, Cave JW.

Neurosci Lett. 2016 Jun 20;625:20-5. doi: 10.1016/j.neulet.2015.12.003. Epub 2015 Dec 8. Review.


Aspects of mental health dysfunction among survivors of childhood cancer.

Fidler MM, Ziff OJ, Wang S, Cave J, Janardhanan P, Winter DL, Kelly J, Mehta S, Jenkinson H, Frobisher C, Reulen RC, Hawkins MM.

Br J Cancer. 2015 Sep 29;113(7):1121-32. doi: 10.1038/bjc.2015.310.


TMPyP4, a Stabilizer of Nucleic Acid Secondary Structure, Is a Novel Acetylcholinesterase Inhibitor.

Fujiwara N, Mazzola M, Cai E, Wang M, Cave JW.

PLoS One. 2015 Sep 24;10(9):e0139167. doi: 10.1371/journal.pone.0139167. eCollection 2015.


Targeting the vasculature to improve neural progenitor transplant survival.

Hill J, Cave J.

Transl Neurosci. 2015 Aug 27;6(1):162-167. doi: 10.1515/tnsci-2015-0016. eCollection 2015. Review.


James Cave: Torn to shreds by Sister Harvey.

Cave J.

BMJ. 2015 Jul 8;351:h3625. doi: 10.1136/bmj.h3625. No abstract available.


Improving health outcomes for young people with long term conditions: The role of digital communication in current and future patient-clinician communication for NHS providers of specialist clinical services for young people - LYNC study protocol.

Griffiths FE, Atherton H, Barker JR, Cave JA, Dennick K, Dowdall P, Fraser J, Huxley C, Kim SW, Madan JJ, Matharu H, Musumadi L, Palmer TM, Paul M, Sankaranarayanan S, Slowther AM, Sujan MA, Sutcliffe PA, Sturt J.

Digit Health. 2015 Jun 29;1:2055207615593698. doi: 10.1177/2055207615593698. eCollection 2015 Jan-Dec.


Regulation of tyrosine hydroxylase transcription by hnRNP K and DNA secondary structure.

Banerjee K, Wang M, Cai E, Fujiwara N, Baker H, Cave JW.

Nat Commun. 2014 Dec 10;5:5769. doi: 10.1038/ncomms6769.

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