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Items: 1 to 50 of 198

1.

Methotrexate Restores CD73 Expression on Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis Patients and May Contribute to Its Anti-Inflammatory Effect through Ado Production.

Bossennec M, Rodriguez C, Hubert M, Di-Roio A, Machon C, Guitton J, Battiston-Montagne P, Couturier M, Marotte H, Caux C, Coury F, Ménétrier-Caux C.

J Clin Med. 2019 Nov 3;8(11). pii: E1859. doi: 10.3390/jcm8111859.

2.

Redefining malignant pleural mesothelioma types as a continuum uncovers immune-vascular interactions.

Alcala N, Mangiante L, Le-Stang N, Gustafson CE, Boyault S, Damiola F, Alcala K, Brevet M, Thivolet-Bejui F, Blanc-Fournier C, Le Rochais JP, Planchard G, Rousseau N, Damotte D, Pairon JC, Copin MC, Scherpereel A, Wasielewski E, Wicquart L, Lacomme S, Vignaud JM, Ancelin G, Girard C, Sagan C, Bonnetaud C, Hofman V, Hofman P, Mouroux J, Thomas de Montpreville V, Clermont-Taranchon E, Mazieres J, Rouquette I, Begueret H, Blay JY, Lantuejoul S, Bueno R, Caux C, Girard N, McKay JD, Foll M, Galateau-Salle F, Fernandez-Cuesta L.

EBioMedicine. 2019 Oct;48:191-202. doi: 10.1016/j.ebiom.2019.09.003. Epub 2019 Oct 21.

3.

Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade.

Shekarian T, Sivado E, Jallas AC, Depil S, Kielbassa J, Janoueix-Lerosey I, Hutter G, Goutagny N, Bergeron C, Viari A, Valsesia-Wittmann S, Caux C, Marabelle A.

Sci Transl Med. 2019 Oct 23;11(515). pii: eaat5025. doi: 10.1126/scitranslmed.aat5025.

PMID:
31645452
4.

Association between FGFR1 copy numbers, MAP3K1 mutations, and survival in axillary node-positive, hormone receptor-positive, and HER2-negative early breast cancer in the PACS04 and METABRIC studies.

Carene D, Tran-Dien A, Lemonnier J, Dalenc F, Levy C, Pierga JY, Jacot W, Canon JL, Richon C, Lacroix L, Caux C, André F, Michiels S.

Breast Cancer Res Treat. 2019 Oct 16. doi: 10.1007/s10549-019-05462-y. [Epub ahead of print]

PMID:
31620934
5.

Neutrophil Heterogeneity in Cancer: From Biology to Therapies.

Lecot P, Sarabi M, Pereira Abrantes M, Mussard J, Koenderman L, Caux C, Bendriss-Vermare N, Michallet MC.

Front Immunol. 2019 Sep 20;10:2155. doi: 10.3389/fimmu.2019.02155. eCollection 2019. Review.

6.

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells.

Mastelic-Gavillet B, Navarro Rodrigo B, Décombaz L, Wang H, Ercolano G, Ahmed R, Lozano LE, Ianaro A, Derré L, Valerio M, Tawadros T, Jichlinski P, Nguyen-Ngoc T, Speiser DE, Verdeil G, Gestermann N, Dormond O, Kandalaft L, Coukos G, Jandus C, Ménétrier-Caux C, Caux C, Ho PC, Romero P, Harari A, Vigano S.

J Immunother Cancer. 2019 Oct 10;7(1):257. doi: 10.1186/s40425-019-0719-5.

7.

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.

Alcala N, Leblay N, Gabriel AAG, Mangiante L, Hervas D, Giffon T, Sertier AS, Ferrari A, Derks J, Ghantous A, Delhomme TM, Chabrier A, Cuenin C, Abedi-Ardekani B, Boland A, Olaso R, Meyer V, Altmuller J, Le Calvez-Kelm F, Durand G, Voegele C, Boyault S, Moonen L, Lemaitre N, Lorimier P, Toffart AC, Soltermann A, Clement JH, Saenger J, Field JK, Brevet M, Blanc-Fournier C, Galateau-Salle F, Le Stang N, Russell PA, Wright G, Sozzi G, Pastorino U, Lacomme S, Vignaud JM, Hofman V, Hofman P, Brustugun OT, Lund-Iversen M, Thomas de Montpreville V, Muscarella LA, Graziano P, Popper H, Stojsic J, Deleuze JF, Herceg Z, Viari A, Nuernberg P, Pelosi G, Dingemans AMC, Milione M, Roz L, Brcic L, Volante M, Papotti MG, Caux C, Sandoval J, Hernandez-Vargas H, Brambilla E, Speel EJM, Girard N, Lantuejoul S, McKay JD, Foll M, Fernandez-Cuesta L.

Nat Commun. 2019 Aug 20;10(1):3407. doi: 10.1038/s41467-019-11276-9.

8.

Pattern recognition receptors: immune targets to enhance cancer immunotherapy.

Shekarian T, Valsesia-Wittmann S, Brody J, C Michallet M, Depil S, Caux C, Marabelle A.

Ann Oncol. 2019 Aug 13. pii: mdz225. doi: 10.1093/annonc/mdz225. [Epub ahead of print] No abstract available.

PMID:
31408086
9.

Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses.

Hubert M, Gobbini E, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J.

Cancers (Basel). 2019 Jul 30;11(8). pii: E1082. doi: 10.3390/cancers11081082. Review.

10.

Immune checkpoint inhibitor treatment in patients with oncogene- addicted non-small cell lung cancer (NSCLC): summary of a multidisciplinary round-table discussion.

Berghoff AS, Bellosillo B, Caux C, de Langen A, Mazieres J, Normanno N, Preusser M, Provencio M, Rojo F, Wolf J, Zielinski CC.

ESMO Open. 2019 Jun 17;4(3):e000498. doi: 10.1136/esmoopen-2019-000498. eCollection 2019. Review.

11.

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.

Vigano S, Alatzoglou D, Irving M, Ménétrier-Caux C, Caux C, Romero P, Coukos G.

Front Immunol. 2019 Jun 6;10:925. doi: 10.3389/fimmu.2019.00925. eCollection 2019. Review.

12.

A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system.

Burlion A, Ramos RN, Kc P, Sendeyo K, Corneau A, Ménétrier-Caux C, Piaggio E, Olive D, Caux C, Marodon G.

Oncoimmunology. 2019 Apr 12;8(7):1596005. doi: 10.1080/2162402X.2019.1596005. eCollection 2019.

13.

Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

Ménétrier-Caux C, Ray-Coquard I, Blay JY, Caux C.

J Immunother Cancer. 2019 Mar 28;7(1):85. doi: 10.1186/s40425-019-0549-5. Review.

14.

Cold Tumors: A Therapeutic Challenge for Immunotherapy.

Bonaventura P, Shekarian T, Alcazer V, Valladeau-Guilemond J, Valsesia-Wittmann S, Amigorena S, Caux C, Depil S.

Front Immunol. 2019 Feb 8;10:168. doi: 10.3389/fimmu.2019.00168. eCollection 2019. Review.

15.

Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues.

Sciarra A, Monteiro I, Ménétrier-Caux C, Caux C, Gilbert B, Halkic N, La Rosa S, Romero P, Sempoux C, de Leval L.

Cancer Immunol Immunother. 2019 Mar;68(3):529. doi: 10.1007/s00262-019-02309-9.

PMID:
30721340
16.

Immunothérapie par ciblage des points de contrôle immunologique et thérapie cellulaire : ou comment l’une et l’autre se complètent pour un même combat.

Caux C, Bay JO.

Bull Cancer. 2018 Dec;105 Suppl 2:S133-S134. doi: 10.1016/S0007-4551(19)30043-8. French. No abstract available.

PMID:
30686351
17.

Neoepitopes-based vaccines: challenges and perspectives.

Alcazer V, Bonaventura P, Tonon L, Wittmann S, Caux C, Depil S.

Eur J Cancer. 2019 Feb;108:55-60. doi: 10.1016/j.ejca.2018.12.011. Epub 2019 Jan 12.

PMID:
30648630
18.

[Some important breakthroughs in oncology and hematology in 2018: A selection by the editorial board of Bulletin du Cancer].

Bay JO, André T, Caux C, Evrard S, Gonçalves A, L'Allemain G, Magné N, Orbach D, Penel N, Rodrigues M, Thariat J, Thiery-Vuillemin A, Wislez M; Comité de Rédaction du Bulletin du Cancer.

Bull Cancer. 2019 Jan;106(1):12-23. doi: 10.1016/j.bulcan.2018.12.005. Epub 2019 Jan 3. Review. French.

PMID:
30612698
19.

CD73 expression in normal and pathological human hepatobiliopancreatic tissues.

Sciarra A, Monteiro I, Ménétrier-Caux C, Caux C, Gilbert B, Halkic N, La Rosa S, Romero P, Sempoux C, de Leval L.

Cancer Immunol Immunother. 2019 Mar;68(3):467-478. doi: 10.1007/s00262-018-2290-1. Epub 2019 Jan 4. Erratum in: Cancer Immunol Immunother. 2019 Feb 5;:.

PMID:
30607549
20.

Nouvelles perspectives dans l’immunothérapie des cancers.

Caux C, Bay JO.

Bull Cancer. 2018 Dec;105 Suppl 1:S1-S2. doi: 10.1016/S0007-4551(18)30384-9. French.

PMID:
30595190
21.

MDR1 in immunity: friend or foe?

Bossennec M, Di Roio A, Caux C, Ménétrier-Caux C.

Oncoimmunology. 2018 Sep 6;7(12):e1499388. doi: 10.1080/2162402X.2018.1499388. eCollection 2018. Review.

22.

Immunological and classical subtypes of oral premalignant lesions.

Foy JP, Bertolus C, Ortiz-Cuaran S, Albaret MA, Williams WN, Lang W, Destandau S, Souza G, Sohier E, Kielbassa J, Thomas E, Deneuve S, Goudot P, Puisieux A, Viari A, Mao L, Caux C, Lippman SM, Saintigny P.

Oncoimmunology. 2018 Sep 21;7(12):e1496880. doi: 10.1080/2162402X.2018.1496880. eCollection 2018.

23.

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.

Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, Grau M, Macari C, Bauché D, Dumitrescu O, Rasigade JP, Lippens S, Plateroti M, Kress E, Cesaro A, Bondu C, Rothermel U, Heikenwälder M, Lina G, Bentaher-Belaaouaj A, Marie JC, Caux C, Trinchieri G, Marvel J, Michallet MC.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10404-10409. doi: 10.1073/pnas.1722372115. Epub 2018 Sep 24.

24.

CD73 expression and clinical significance in human metastatic melanoma.

Monteiro I, Vigano S, Faouzi M, Treilleux I, Michielin O, Ménétrier-Caux C, Caux C, Romero P, de Leval L.

Oncotarget. 2018 Jun 1;9(42):26659-26669. doi: 10.18632/oncotarget.25426. eCollection 2018 Jun 1.

25.

Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints.

Gourdin N, Bossennec M, Rodriguez C, Vigano S, Machon C, Jandus C, Bauché D, Faget J, Durand I, Chopin N, Tredan O, Marie JC, Dubois B, Guitton J, Romero P, Caux C, Ménétrier-Caux C.

Cancer Res. 2018 Jul 1;78(13):3604-3618. doi: 10.1158/0008-5472.CAN-17-2405. Epub 2018 Mar 20.

26.

Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration.

Small M, Treilleux I, Couillault C, Pissaloux D, Picard G, Paindavoine S, Attignon V, Wang Q, Rogemond V, Lay S, Ray-Coquard I, Pfisterer J, Joly F, Du Bois A, Psimaras D, Bendriss-Vermare N, Caux C, Dubois B, Honnorat J, Desestret V.

Acta Neuropathol. 2018 Apr;135(4):569-579. doi: 10.1007/s00401-017-1802-y. Epub 2018 Jan 3.

PMID:
29299667
27.

[Hot topics in 2017 in oncology and hematology. A selection by the editorial board of Bulletin du Cancer].

Vignot S, André T, Caux C, Bouleuc C, Evrard S, Gonçalves A, Lacroix M, Magné N, Massard C, Mazeron JJ, Orbach D, Rodrigues M, Thariat J, Wislez M, L'Allemain G, Bay JO.

Bull Cancer. 2018 Jan;105(1):6-14. doi: 10.1016/j.bulcan.2017.11.006. Review. French.

PMID:
29269176
28.

Consent to care of persons with intellectual disability in Quebec: from vulnerability to capability.

Caux C, Lecomte J.

Salud Publica Mex. 2017 Jul-Aug;59(4):462-467. doi: 10.21149/8206.

PMID:
29211268
29.

BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells.

Combes A, Camosseto V, N'Guessan P, Argüello RJ, Mussard J, Caux C, Bendriss-Vermare N, Pierre P, Gatti E.

Nat Commun. 2017 Oct 13;8(1):913. doi: 10.1038/s41467-017-00695-1.

30.

Emerging Role of the Unfolded Protein Response in Tumor Immunosurveillance.

Vanacker H, Vetters J, Moudombi L, Caux C, Janssens S, Michallet MC.

Trends Cancer. 2017 Jul;3(7):491-505. doi: 10.1016/j.trecan.2017.05.005. Epub 2017 Jul 6. Review.

PMID:
28718404
31.

The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade.

Foy JP, Bertolus C, Michallet MC, Deneuve S, Incitti R, Bendriss-Vermare N, Albaret MA, Ortiz-Cuaran S, Thomas E, Colombe A, Py C, Gadot N, Michot JP, Fayette J, Viari A, Van den Eynde B, Goudot P, Devouassoux-Shisheboran M, Puisieux A, Caux C, Zrounba P, Lantuejoul S, Saintigny P.

Ann Oncol. 2017 Aug 1;28(8):1934-1941. doi: 10.1093/annonc/mdx210.

32.

Pattern recognition receptors: immune targets to enhance cancer immunotherapy.

Shekarian T, Valsesia-Wittmann S, Brody J, Michallet MC, Depil S, Caux C, Marabelle A.

Ann Oncol. 2017 Aug 1;28(8):1756-1766. doi: 10.1093/annonc/mdx179. Review.

PMID:
28444111
33.

ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients.

Trédan O, Ménétrier-Caux C, Ray-Coquard I, Garin G, Cropet C, Verronèse E, Bachelot T, Rebattu P, E Heudel P, Cassier P, Chabaud S, Croughs T, Dupont P, C Cadore A, Clapisson G, Delgado A, Bardin-Dit-Courageot C, Rigal C, N'Kodia A, Gilles-Afchain L, Morre M, Pérol D, Blay JY, Caux C.

Ann Oncol. 2018 Feb 1;29(2):523. doi: 10.1093/annonc/mdx058. No abstract available.

PMID:
28368453
34.

Description of the immune microenvironment of chondrosarcoma and contribution to progression.

Simard FA, Richert I, Vandermoeten A, Decouvelaere AV, Michot JP, Caux C, Blay JY, Dutour A.

Oncoimmunology. 2016 Dec 7;6(2):e1265716. doi: 10.1080/2162402X.2016.1265716. eCollection 2017.

35.

A Milestone Review on How Macrophages Affect Tumor Growth.

Caux C, Ramos RN, Prendergast GC, Bendriss-Vermare N, Ménétrier-Caux C.

Cancer Res. 2016 Nov 15;76(22):6439-6442. doi: 10.1158/0008-5472.CAN-16-2631. No abstract available.

36.

Les entérobactéries productrices de carbapénémases.

Boivin S, Caux C, Soucy C, Allard A.

Perspect Infirm. 2016 Nov-Dec;13(5):53-56. Review. French. No abstract available.

PMID:
29381281
37.

Ethical competence: An integrative review.

Lechasseur K, Caux C, Dollé S, Legault A.

Nurs Ethics. 2018 Sep;25(6):694-706. doi: 10.1177/0969733016667773. Epub 2016 Sep 30. Review.

PMID:
27694548
38.

TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression.

Parroche P, Roblot G, Le Calvez-Kelm F, Tout I, Marotel M, Malfroy M, Durand G, McKay J, Ainouze M, Carreira C, Allatif O, Traverse-Glehen A, Mendiola M, Pozo-Kreilinger JJ, Caux C, Tommasino M, Goutagny N, Hasan UA.

Oncogenesis. 2016 Jul 25;5(7):e244. doi: 10.1038/oncsis.2016.49.

39.

Follicular B Lymphomas Generate Regulatory T Cells via the ICOS/ICOSL Pathway and Are Susceptible to Treatment by Anti-ICOS/ICOSL Therapy.

Le KS, Thibult ML, Just-Landi S, Pastor S, Gondois-Rey F, Granjeaud S, Broussais F, Bouabdallah R, Colisson R, Caux C, Ménétrier-Caux C, Leroux D, Xerri L, Olive D.

Cancer Res. 2016 Aug 15;76(16):4648-60. doi: 10.1158/0008-5472.CAN-15-0589. Epub 2016 May 31.

40.

Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay.

Verronèse E, Delgado A, Valladeau-Guilemond J, Garin G, Guillemaut S, Tredan O, Ray-Coquard I, Bachelot T, N'Kodia A, Bardin-Dit-Courageot C, Rigal C, Pérol D, Caux C, Ménétrier-Caux C.

Oncoimmunology. 2015 Nov 10;5(3):e1100791. eCollection 2016 Mar.

41.

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage.

Dezutter-Dambuyant C, Durand I, Alberti L, Bendriss-Vermare N, Valladeau-Guilemond J, Duc A, Magron A, Morel AP, Sisirak V, Rodriguez C, Cox D, Olive D, Caux C.

Oncoimmunology. 2015 Oct 29;5(3):e1091146. eCollection 2016 Mar.

42.

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway.

Viel S, Marçais A, Guimaraes FS, Loftus R, Rabilloud J, Grau M, Degouve S, Djebali S, Sanlaville A, Charrier E, Bienvenu J, Marie JC, Caux C, Marvel J, Town L, Huntington ND, Bartholin L, Finlay D, Smyth MJ, Walzer T.

Sci Signal. 2016 Feb 16;9(415):ra19. doi: 10.1126/scisignal.aad1884.

PMID:
26884601
43.

In Vitro and In Vivo Comparison of Lymphocytes Transduced with a Human CD16 or with a Chimeric Antigen Receptor Reveals Potential Off-Target Interactions due to the IgG2 CH2-CH3 CAR-Spacer.

Clémenceau B, Valsesia-Wittmann S, Jallas AC, Vivien R, Rousseau R, Marabelle A, Caux C, Vié H.

J Immunol Res. 2015;2015:482089. doi: 10.1155/2015/482089. Epub 2015 Nov 17.

44.

[A multidisciplinary approach to cardiac rehabilitation].

Barbet R, Caux C, Brysse L, Foy M, Cardon C.

Soins. 2015 Mar;(793):52-6. French.

PMID:
26040143
45.

Breast Cancer Cell-Derived GM-CSF Licenses Regulatory Th2 Induction by Plasmacytoid Predendritic Cells in Aggressive Disease Subtypes.

Ghirelli C, Reyal F, Jeanmougin M, Zollinger R, Sirven P, Michea P, Caux C, Bendriss-Vermare N, Donnadieu MH, Caly M, Fourchotte V, Vincent-Salomon A, Sigal-Zafrani B, Sastre-Garau X, Soumelis V.

Cancer Res. 2015 Jul 15;75(14):2775-87. doi: 10.1158/0008-5472.CAN-14-2386. Epub 2015 May 14.

46.

ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients.

Trédan O, Ménétrier-Caux C, Ray-Coquard I, Garin G, Cropet C, Verronèse E, Bachelot T, Rebattu P, Heudel PE, Cassier P, Chabaud S, Croughs T, Dupont P, Cadore AC, Clapisson G, Delgado A, Bardin-dit-Courageot C, Rigal C, N'Kodia A, Gilles-Afchain L, Morre M, Pérol D, Blay JY, Caux C.

Ann Oncol. 2015 Jul;26(7):1353-62. doi: 10.1093/annonc/mdv173. Epub 2015 Apr 7. Erratum in: Ann Oncol. 2018 Feb 1;29(2):523.

PMID:
25851629
47.

PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.

Mathieu AL, Verronese E, Rice GI, Fouyssac F, Bertrand Y, Picard C, Chansel M, Walter JE, Notarangelo LD, Butte MJ, Nadeau KC, Csomos K, Chen DJ, Chen K, Delgado A, Rigal C, Bardin C, Schuetz C, Moshous D, Reumaux H, Plenat F, Phan A, Zabot MT, Balme B, Viel S, Bienvenu J, Cochat P, van der Burg M, Caux C, Kemp EH, Rouvet I, Malcus C, Méritet JF, Lim A, Crow YJ, Fabien N, Ménétrier-Caux C, De Villartay JP, Walzer T, Belot A.

J Allergy Clin Immunol. 2015 Jun;135(6):1578-88.e5. doi: 10.1016/j.jaci.2015.01.040. Epub 2015 Apr 2.

48.

Paradigm shift in oncology: targeting the immune system rather than cancer cells.

Shekarian T, Valsesia-Wittmann S, Caux C, Marabelle A.

Mutagenesis. 2015 Mar;30(2):205-11. doi: 10.1093/mutage/geu073. Review.

PMID:
25688113
49.

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.

Chapellier M, Bachelard-Cascales E, Schmidt X, Clément F, Treilleux I, Delay E, Jammot A, Ménétrier-Caux C, Pochon G, Besançon R, Voeltzel T, Caron de Fromentel C, Caux C, Blay JY, Iggo R, Maguer-Satta V.

Stem Cell Reports. 2015 Feb 10;4(2):239-54. doi: 10.1016/j.stemcr.2014.12.007. Epub 2015 Jan 15.

50.

TLR9 transcriptional regulation in response to double-stranded DNA viruses.

Zannetti C, Parroche P, Panaye M, Roblot G, Gruffat H, Manet E, Debaud AL, Plumas J, Vey N, Caux C, Bendriss-Vermare N, Hasan UA.

J Immunol. 2014 Oct 1;193(7):3398-408. doi: 10.4049/jimmunol.1400249. Epub 2014 Sep 5.

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