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Items: 48


Per- and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived model.

Steves AN, Turry A, Gill B, Clarkson-Townsend D, Bradner JM, Bachli I, Caudle WM, Miller GW, Chan AWS, Easley CA 4th.

Syst Biol Reprod Med. 2018 Aug;64(4):225-239. doi: 10.1080/19396368.2018.1481465. Epub 2018 Jun 18.


Ubiquitous Flame-Retardant Toxicants Impair Spermatogenesis in a Human Stem Cell Model.

Steves AN, Bradner JM, Fowler KL, Clarkson-Townsend D, Gill BJ, Turry AC, Caudle WM, Miller GW, Chan AWS, Easley CA 4th.

iScience. 2018 May 25;3:161-176. doi: 10.1016/j.isci.2018.04.014.


Occupational Metal Exposure and Parkinsonism.

Caudle WM.

Adv Neurobiol. 2017;18:143-158. doi: 10.1007/978-3-319-60189-2_7. Review.


Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.

Dunn AR, Stout KA, Ozawa M, Lohr KM, Hoffman CA, Bernstein AI, Li Y, Wang M, Sgobio C, Sastry N, Cai H, Caudle WM, Miller GW.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2253-E2262. doi: 10.1073/pnas.1616892114. Epub 2017 Feb 28.


Impairment in the mesohippocampal dopamine circuit following exposure to the brominated flame retardant, HBCDD.

Pham-Lake C, Aronoff EB, Camp CR, Vester A, Peters SJ, Caudle WM.

Environ Toxicol Pharmacol. 2017 Mar;50:167-174. doi: 10.1016/j.etap.2017.02.003. Epub 2017 Feb 4.


Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain.

Cliburn RA, Dunn AR, Stout KA, Hoffman CA, Lohr KM, Bernstein AI, Winokur EJ, Burkett J, Schmitz Y, Caudle WM, Miller GW.

J Chem Neuroanat. 2017 Oct;83-84:82-90. doi: 10.1016/j.jchemneu.2016.11.003. Epub 2016 Nov 9.


The Synapse as a Central Target for Neurodevelopmental Susceptibility to Pesticides.

Vester A, Caudle WM.

Toxics. 2016 Aug 26;4(3). pii: E18. doi: 10.3390/toxics4030018. Review.


Alteration to Dopaminergic Synapses Following Exposure to Perfluorooctane Sulfonate (PFOS), in Vitro and in Vivo.

Patel R, Bradner JM, Stout KA, Caudle WM.

Med Sci (Basel). 2016 Aug 16;4(3). pii: E13. doi: 10.3390/medsci4030013.


Unmasking silent neurotoxicity following developmental exposure to environmental toxicants.

Kraft AD, Aschner M, Cory-Slechta DA, Bilbo SD, Caudle WM, Makris SL.

Neurotoxicol Teratol. 2016 May-Jun;55:38-44. doi: 10.1016/ Epub 2016 Apr 2. Review.


Occupational exposures and parkinsonism.

Caudle WM.

Handb Clin Neurol. 2015;131:225-39. doi: 10.1016/B978-0-444-62627-1.00013-5. Review.


Comparative Proteomic Analysis of Carbonylated Proteins from the Striatum and Cortex of Pesticide-Treated Mice.

Coughlan C, Walker DI, Lohr KM, Richardson JR, Saba LM, Caudle WM, Fritz KS, Roede JR.

Parkinsons Dis. 2015;2015:812532. doi: 10.1155/2015/812532. Epub 2015 Aug 9.


Selective damage to dopaminergic transporters following exposure to the brominated flame retardant, HBCDD.

Genskow KR, Bradner JM, Hossain MM, Richardson JR, Caudle WM.

Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt B):162-9. doi: 10.1016/ Epub 2015 Jun 12.


Assessing reproductive toxicity of two environmental toxicants with a novel in vitro human spermatogenic model.

Easley CA 4th, Bradner JM, Moser A, Rickman CA, McEachin ZT, Merritt MM, Hansen JM, Caudle WM.

Stem Cell Res. 2015 May;14(3):347-55. doi: 10.1016/j.scr.2015.03.002. Epub 2015 Mar 25.


Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder.

Richardson JR, Taylor MM, Shalat SL, Guillot TS 3rd, Caudle WM, Hossain MM, Mathews TA, Jones SR, Cory-Slechta DA, Miller GW.

FASEB J. 2015 May;29(5):1960-72. doi: 10.1096/fj.14-260901. Epub 2015 Jan 28.


Developmental exposure to the organochlorine insecticide endosulfan damages the nigrostriatal dopamine system in male offspring.

Wilson WW, Shapiro LP, Bradner JM, Caudle WM.

Neurotoxicology. 2014 Sep;44:279-87. doi: 10.1016/j.neuro.2014.07.008. Epub 2014 Aug 2.


Developmental exposure to the organochlorine insecticide endosulfan alters expression of proteins associated with neurotransmission in the frontal cortex.

Wilson WW, Onyenwe W, Bradner JM, Nennig SE, Caudle WM.

Synapse. 2014 Nov;68(11):485-97. doi: 10.1002/syn.21764. Epub 2014 Jul 25.


Alterations to the circuitry of the frontal cortex following exposure to the polybrominated diphenyl ether mixture, DE-71.

Bradner JM, Suragh TA, Caudle WM.

Toxicology. 2013 Oct 4;312:48-55. doi: 10.1016/j.tox.2013.07.015. Epub 2013 Jul 31.


Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity.

Bradner JM, Suragh TA, Wilson WW, Lazo CR, Stout KA, Kim HM, Wang MZ, Walker DI, Pennell KD, Richardson JR, Miller GW, Caudle WM.

Exp Neurol. 2013 Mar;241:138-47. doi: 10.1016/j.expneurol.2012.12.013. Epub 2012 Dec 31.


Parkinson's disease and the environment: beyond pesticides.

Caudle WM, Guillot TS, Lazo C, Miller GW.

Neurotoxicology. 2012 Jun;33(3):585. No abstract available.


Industrial toxicants and Parkinson's disease.

Caudle WM, Guillot TS, Lazo CR, Miller GW.

Neurotoxicology. 2012 Mar;33(2):178-88. doi: 10.1016/j.neuro.2012.01.010. Epub 2012 Jan 30. Review.


VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease.

Taylor TN, Caudle WM, Miller GW.

Parkinsons Dis. 2011 Feb 21;2011:124165. doi: 10.4061/2011/124165.


Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease.

Caudle WM, Bammler TK, Lin Y, Pan S, Zhang J.

Expert Rev Neurother. 2010 Jun;10(6):925-42. doi: 10.1586/ern.10.54. Review.


Glutamate, excitotoxicity, and programmed cell death in Parkinson disease.

Caudle WM, Zhang J.

Exp Neurol. 2009 Dec;220(2):230-3. doi: 10.1016/j.expneurol.2009.09.027. Epub 2009 Oct 6. Review. No abstract available.


Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity.

Taylor TN, Caudle WM, Shepherd KR, Noorian A, Jackson CR, Iuvone PM, Weinshenker D, Greene JG, Miller GW.

J Neurosci. 2009 Jun 24;29(25):8103-13. doi: 10.1523/JNEUROSCI.1495-09.2009.


A role for a novel protein, nucleolin, in Parkinson's disease.

Caudle WM, Kitsou E, Li J, Bradner J, Zhang J.

Neurosci Lett. 2009 Jul 31;459(1):11-5. doi: 10.1016/j.neulet.2009.04.060. Epub 2009 May 4.


Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

Hu X, Zhang D, Pang H, Caudle WM, Li Y, Gao H, Liu Y, Qian L, Wilson B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS.

J Immunol. 2008 Nov 15;181(10):7194-204.


Biomarker discovery in neurodegenerative diseases: a proteomic approach.

Shi M, Caudle WM, Zhang J.

Neurobiol Dis. 2009 Aug;35(2):157-64. doi: 10.1016/j.nbd.2008.09.004. Epub 2008 Sep 26. Review.


Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative disease.

Caudle WM, Pan S, Shi M, Quinn T, Hoekstra J, Beyer RP, Montine TJ, Zhang J.

Proteomics Clin Appl. 2008 Oct;2(10-11):1484-97. doi: 10.1002/prca.200800043. Epub 2008 Sep 10.


Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner.

Richardson JR, Caudle WM, Wang MZ, Dean ED, Pennell KD, Miller GW.

Neurotoxicology. 2008 Sep;29(5):855-63. doi: 10.1016/j.neuro.2008.05.007. Epub 2008 Jun 5.


Altered vesicular dopamine storage in Parkinson's disease: a premature demise.

Caudle WM, Colebrooke RE, Emson PC, Miller GW.

Trends Neurosci. 2008 Jun;31(6):303-8. doi: 10.1016/j.tins.2008.02.010. Epub 2008 May 9. Review.


Identification of proteins in human substantia nigra.

Kitsou E, Pan S, Zhang J, Shi M, Zabeti A, Dickson DW, Albin R, Gearing M, Kashima DT, Wang Y, Beyer RP, Zhou Y, Pan C, Caudle WM, Zhang J.

Proteomics Clin Appl. 2008 May;2(5):776-82. doi: 10.1002/prca.200800028.


Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration.

Caudle WM, Richardson JR, Wang MZ, Taylor TN, Guillot TS, McCormack AL, Colebrooke RE, Di Monte DA, Emson PC, Miller GW.

J Neurosci. 2007 Jul 25;27(30):8138-48.


Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1.

Hamill CE, Caudle WM, Richardson JR, Yuan H, Pennell KD, Greene JG, Miller GW, Traynelis SF.

Mol Pharmacol. 2007 Sep;72(3):653-64. Epub 2007 Jun 27.


Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter.

Manning-Boğ AB, Caudle WM, Perez XA, Reaney SH, Paletzki R, Isla MZ, Chou VP, McCormack AL, Miller GW, Langston JW, Gerfen CR, Dimonte DA.

Neurobiol Dis. 2007 Aug;27(2):141-50. Epub 2007 May 3.


Altered ethanol-associated behaviors in vesicular monoamine transporter heterozygote knockout mice.

Savelieva KV, Caudle WM, Miller GW.

Alcohol. 2006 Oct;40(2):87-94.


Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Richardson JR, Caudle WM, Guillot TS, Watson JL, Nakamaru-Ogiso E, Seo BB, Sherer TB, Greenamyre JT, Yagi T, Matsuno-Yagi A, Miller GW.

Toxicol Sci. 2007 Jan;95(1):196-204. Epub 2006 Oct 12.


Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease.

Richardson JR, Caudle WM, Wang M, Dean ED, Pennell KD, Miller GW.

FASEB J. 2006 Aug;20(10):1695-7. Epub 2006 Jun 29.


Olfactory discrimination deficits in mice lacking the dopamine transporter or the D2 dopamine receptor.

Tillerson JL, Caudle WM, Parent JM, Gong C, Schallert T, Miller GW.

Behav Brain Res. 2006 Sep 15;172(1):97-105. Epub 2006 Jun 9.


Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity.

Caudle WM, Richardson JR, Delea KC, Guillot TS, Wang M, Pennell KD, Miller GW.

Toxicol Sci. 2006 Aug;92(2):490-9. Epub 2006 May 15.


Use-dependent behavioral and neurochemical asymmetry in MPTP mice.

Caudle WM, Tillerson JL, Reverón ME, Miller GW.

Neurosci Lett. 2007 May 18;418(3):213-6. Epub 2006 Apr 17.


Perinatal heptachlor exposure increases expression of presynaptic dopaminergic markers in mouse striatum.

Caudle WM, Richardson JR, Wang M, Miller GW.

Neurotoxicology. 2005 Aug;26(4):721-728. doi: 10.1016/j.neuro.2004.09.003.


Pyrethroid pesticide-induced alterations in dopamine transporter function.

Elwan MA, Richardson JR, Guillot TS, Caudle WM, Miller GW.

Toxicol Appl Pharmacol. 2006 Mar 15;211(3):188-97. Epub 2005 Jul 11.


Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease.

Tillerson JL, Caudle WM, Reverón ME, Miller GW.

Neuroscience. 2003;119(3):899-911.


Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling.

Decker MJ, Hue GE, Caudle WM, Miller GW, Keating GL, Rye DB.

Neuroscience. 2003;117(2):417-25.


Forced nonuse in unilateral parkinsonian rats exacerbates injury.

Tillerson JL, Cohen AD, Caudle WM, Zigmond MJ, Schallert T, Miller GW.

J Neurosci. 2002 Aug 1;22(15):6790-9.


Decreased ethanol preference and consumption in dopamine transporter female knock-out mice.

Savelieva KV, Caudle WM, Findlay GS, Caron MG, Miller GW.

Alcohol Clin Exp Res. 2002 Jun;26(6):758-64.


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