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Items: 1 to 50 of 176

1.

Pulmonary capillary surface area in supine exercising humans: demonstration of vascular recruitment.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Naeije R, Fox BD, Abualsaud AO, Blenkhorn F, Rudski LG, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2019 Sep 1;317(3):L361-L368. doi: 10.1152/ajplung.00098.2019. Epub 2019 Jun 26.

PMID:
31242024
2.

Acute exposure of mice to hydrochloric acid leads to the development of chronic lung injury and pulmonary fibrosis.

Marinova M, Solopov P, Dimitropoulou C, Colunga Biancatelli RML, Catravas JD.

Inhal Toxicol. 2019 Mar;31(4):147-160. doi: 10.1080/08958378.2019.1624895. Epub 2019 Jun 23.

PMID:
31232121
3.

P53 supports endothelial barrier function via APE1/Ref1 suppression.

Uddin MA, Akhter MS, Siejka A, Catravas JD, Barabutis N.

Immunobiology. 2019 Jul;224(4):532-538. doi: 10.1016/j.imbio.2019.04.008. Epub 2019 Apr 18.

PMID:
31023490
4.

Hsp90 inhibitors suppress P53 phosphorylation in LPS - induced endothelial inflammation.

Barabutis N, Uddin MA, Catravas JD.

Cytokine. 2019 Jan;113:427-432. doi: 10.1016/j.cyto.2018.10.020. Epub 2018 Nov 9.

PMID:
30420201
5.

Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor.

McQueeney KE, Salamoun JM, Burnett JC, Barabutis N, Pekic P, Lewandowski SL, Llaneza DC, Cornelison R, Bai Y, Zhang ZY, Catravas JD, Landen CN, Wipf P, Lazo JS, Sharlow ER.

Oncotarget. 2017 Dec 30;9(9):8223-8240. doi: 10.18632/oncotarget.23787. eCollection 2018 Feb 2.

6.

Wild-type p53 enhances endothelial barrier function by mediating RAC1 signalling and RhoA inhibition.

Barabutis N, Dimitropoulou C, Gregory B, Catravas JD.

J Cell Mol Med. 2018 Mar;22(3):1792-1804. doi: 10.1111/jcmm.13460. Epub 2018 Jan 24.

7.

LPS-induced Acute Lung Injury Involves NF-κB-mediated Downregulation of SOX18.

Gross CM, Kellner M, Wang T, Lu Q, Sun X, Zemskov EA, Noonepalle S, Kangath A, Kumar S, Gonzalez-Garay M, Desai AA, Aggarwal S, Gorshkov B, Klinger C, Verin AD, Catravas JD, Jacobson JR, Yuan JX, Rafikov R, Garcia JGN, Black SM.

Am J Respir Cell Mol Biol. 2018 May;58(5):614-624. doi: 10.1165/rcmb.2016-0390OC.

8.

Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signaling.

Khanal S, Sultana H, Catravas JD, Carlyon JA, Neelakanta G.

PLoS One. 2017 Aug 10;12(8):e0182898. doi: 10.1371/journal.pone.0182898. eCollection 2017.

9.

Hydrocortisone and Ascorbic Acid Synergistically Prevent and Repair Lipopolysaccharide-Induced Pulmonary Endothelial Barrier Dysfunction.

Barabutis N, Khangoora V, Marik PE, Catravas JD.

Chest. 2017 Nov;152(5):954-962. doi: 10.1016/j.chest.2017.07.014. Epub 2017 Jul 21.

10.

Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds.

Vora A, Taank V, Dutta SM, Anderson JF, Fish D, Sonenshine DE, Catravas JD, Sultana H, Neelakanta G.

Sci Rep. 2017 Mar 16;7:44593. doi: 10.1038/srep44593.

11.

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins.

Chen F, Wang Y, Rafikov R, Haigh S, Zhi WB, Kumar S, Doulias PT, Rafikova O, Pillich H, Chakraborty T, Lucas R, Verin AD, Catravas JD, She JX, Black SM, Fulton DJR.

Biochem Pharmacol. 2017 Mar 1;127:34-45. doi: 10.1016/j.bcp.2016.12.014. Epub 2016 Dec 22.

12.

The protective role of MLCP-mediated ERM dephosphorylation in endotoxin-induced lung injury in vitro and in vivo.

Kovacs-Kasa A, Gorshkov BA, Kim KM, Kumar S, Black SM, Fulton DJ, Dimitropoulou C, Catravas JD, Verin AD.

Sci Rep. 2016 Dec 15;6:39018. doi: 10.1038/srep39018.

13.

Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.

Kumar S, Sun X, Noonepalle SK, Lu Q, Zemskov E, Wang T, Aggarwal S, Gross C, Sharma S, Desai AA, Hou Y, Dasarathy S, Qu N, Reddy V, Lee SG, Cherian-Shaw M, Yuan JX, Catravas JD, Rafikov R, Garcia JGN, Black SM.

Free Radic Biol Med. 2017 Jan;102:217-228. doi: 10.1016/j.freeradbiomed.2016.11.008. Epub 2016 Nov 9.

14.

Regulation of pulmonary endothelial barrier function by kinases.

Barabutis N, Verin A, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L832-L845. doi: 10.1152/ajplung.00233.2016. Epub 2016 Sep 23. Review.

15.

Hsp90 inhibition suppresses NF-κB transcriptional activation via Sirt-2 in human lung microvascular endothelial cells.

Thangjam GS, Birmpas C, Barabutis N, Gregory BW, Clemens MA, Newton JR, Fulton D, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L964-74. doi: 10.1152/ajplung.00054.2016. Epub 2016 Apr 1.

16.

Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.

Joshi AD, Barabutis N, Birmpas C, Dimitropoulou C, Thangjam G, Cherian-Shaw M, Dennison J, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1410-9. doi: 10.1152/ajplung.00180.2015. Epub 2015 Oct 23.

17.

p53 protects against LPS-induced lung endothelial barrier dysfunction.

Barabutis N, Dimitropoulou C, Birmpas C, Joshi A, Thangjam G, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L776-87. doi: 10.1152/ajplung.00334.2014. Epub 2015 Feb 20.

18.

Acute vasodilator responsiveness and microvascular recruitment in idiopathic pulmonary arterial hypertension.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Hirsch AM, Blenkhorn F, Lesenko L, Armaganidis A, Catravas JD.

Ann Intern Med. 2015 Jan 20;162(2):154-6. doi: 10.7326/M14-1402. No abstract available.

PMID:
25599356
19.

Commentary: CHIPping away pancreatic tumors?

Joshi AD, Catravas JD.

Ann Transl Med. 2014 Nov;2(11):105. doi: 10.3978/j.issn.2305-5839.2014.11.01. No abstract available.

20.

PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.

Chen F, Kumar S, Yu Y, Aggarwal S, Gross C, Wang Y, Chakraborty T, Verin AD, Catravas JD, Lucas R, Black SM, Fulton DJ.

PLoS One. 2014 Jul 14;9(7):e99823. doi: 10.1371/journal.pone.0099823. eCollection 2014.

21.

NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.

Barman SA, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas JD, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Rafikova O, Rafikov R, Black SM, Jonigk D, Giannis A, Asmis R, Stepp DW, Ramesh G, Fulton DJ.

Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1704-15. doi: 10.1161/ATVBAHA.114.303848. Epub 2014 Jun 19.

22.

Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.

Rafikov R, Dimitropoulou C, Aggarwal S, Kangath A, Gross C, Pardo D, Sharma S, Jezierska-Drutel A, Patel V, Snead C, Lucas R, Verin A, Fulton D, Catravas JD, Black SM.

J Biol Chem. 2014 Feb 21;289(8):4710-22. doi: 10.1074/jbc.M114.547596. Epub 2014 Jan 7.

23.

Novel mechanism of attenuation of LPS-induced NF-κB activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells.

Thangjam GS, Dimitropoulou C, Joshi AD, Barabutis N, Shaw MC, Kovalenkov Y, Wallace CM, Fulton DJ, Patel V, Catravas JD.

Am J Respir Cell Mol Biol. 2014 May;50(5):942-52. doi: 10.1165/rcmb.2013-0214OC.

24.

Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.

Aggarwal S, Gross CM, Kumar S, Dimitropoulou C, Sharma S, Gorshkov BA, Sridhar S, Lu Q, Bogatcheva NV, Jezierska-Drutel AJ, Lucas R, Verin AD, Catravas JD, Black SM.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):614-25. doi: 10.1165/rcmb.2013-0193OC.

25.

Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.

Joshi AD, Dimitropoulou C, Thangjam G, Snead C, Feldman S, Barabutis N, Fulton D, Hou Y, Kumar S, Patel V, Gorshkov B, Verin AD, Black SM, Catravas JD.

Am J Respir Cell Mol Biol. 2014 Jan;50(1):170-9. doi: 10.1165/rcmb.2012-0496OC.

26.

LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.

Barabutis N, Handa V, Dimitropoulou C, Rafikov R, Snead C, Kumar S, Joshi A, Thangjam G, Fulton D, Black SM, Patel V, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15;304(12):L883-93. doi: 10.1152/ajplung.00419.2012. Epub 2013 Apr 12.

27.

Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.

Chen F, Yu Y, Qian J, Wang Y, Cheng B, Dimitropoulou C, Patel V, Chadli A, Rudic RD, Stepp DW, Catravas JD, Fulton DJ.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2989-99. doi: 10.1161/ATVBAHA.112.300361. Epub 2012 Sep 27.

28.

Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.

Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, Cederbaum SD, Fulton DJ, Matthay MA, Caldwell RW, Romero MJ, Chakraborty T.

Am J Respir Cell Mol Biol. 2012 Oct;47(4):445-53. doi: 10.1165/rcmb.2011-0332OC. Epub 2012 May 10.

29.

Hsp90 regulates O-linked β-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked β-N-acetylglucosamine modification in endothelial cells.

Zhang F, Snead CM, Catravas JD.

Am J Physiol Cell Physiol. 2012 Jun 15;302(12):C1786-96. doi: 10.1152/ajpcell.00004.2012. Epub 2012 Apr 11.

30.

Regulation of asthmatic airway relaxation by estrogen and heat shock protein 90.

Intapad S, Dimitropoulou C, Snead C, Piyachaturawat P, Catravas JD.

J Cell Physiol. 2012 Aug;227(8):3036-43. doi: 10.1002/jcp.23045.

PMID:
22016308
31.

Regulation of endothelial barrier function by TGF-β type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.

Antonov AS, Antonova GN, Fujii M, ten Dijke P, Handa V, Catravas JD, Verin AD.

J Cell Physiol. 2012 Feb;227(2):759-71. doi: 10.1002/jcp.22785.

32.

Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production.

Chen F, Pandey D, Chadli A, Catravas JD, Chen T, Fulton DJ.

Antioxid Redox Signal. 2011 Jun;14(11):2107-19. doi: 10.1089/ars.2010.3669. Epub 2011 Mar 13.

33.

C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.

Sun X, Fratz S, Sharma S, Hou Y, Rafikov R, Kumar S, Rehmani I, Tian J, Smith A, Schreiber C, Reiser J, Naumann S, Haag S, Hess J, Catravas JD, Patterson C, Fineman JR, Black SM.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):163-71. doi: 10.1165/rcmb.2009-0467OC. Epub 2010 Sep 24.

34.

αVβ3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-κB activation.

Antonov AS, Antonova GN, Munn DH, Mivechi N, Lucas R, Catravas JD, Verin AD.

J Cell Physiol. 2011 Feb;226(2):469-76. doi: 10.1002/jcp.22356.

35.

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.

Xiong C, Yang G, Kumar S, Aggarwal S, Leustik M, Snead C, Hamacher J, Fischer B, Umapathy NS, Hossain H, Wendel A, Catravas JD, Verin AD, Fulton D, Black SM, Chakraborty T, Lucas R.

Vascul Pharmacol. 2010 May-Jun;52(5-6):207-13. doi: 10.1016/j.vph.2009.12.010. Epub 2010 Jan 13.

36.

Harvesting, identification and barrier function of human lung microvascular endothelial cells.

Catravas JD, Snead C, Dimitropoulou C, Chang AS, Lucas R, Verin AD, Black SM.

Vascul Pharmacol. 2010 May-Jun;52(5-6):175-81. doi: 10.1016/j.vph.2009.12.009. Epub 2010 Jan 11.

37.

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.

Sharma S, Smith A, Kumar S, Aggarwal S, Rehmani I, Snead C, Harmon C, Fineman J, Fulton D, Catravas JD, Black SM.

Vascul Pharmacol. 2010 May-Jun;52(5-6):182-90. doi: 10.1016/j.vph.2009.11.010. Epub 2009 Dec 3.

38.

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

Tian J, Smith A, Nechtman J, Podolsky R, Aggarwal S, Snead C, Kumar S, Elgaish M, Oishi P, Göerlach A, Fratz S, Hess J, Catravas JD, Verin AD, Fineman JR, She JX, Black SM.

Physiol Genomics. 2009 Dec 30;40(1):48-60. doi: 10.1152/physiolgenomics.00094.2009. Epub 2009 Oct 13.

39.

Regulators of endothelial and epithelial barrier integrity and function in acute lung injury.

Lucas R, Verin AD, Black SM, Catravas JD.

Biochem Pharmacol. 2009 Jun 15;77(12):1763-72. doi: 10.1016/j.bcp.2009.01.014. Epub 2009 Feb 3. Review.

40.

Estrogen replacement therapy prevents airway dysfunction in a murine model of allergen-induced asthma.

Dimitropoulou C, Drakopanagiotakis F, Chatterjee A, Snead C, Catravas JD.

Lung. 2009 Mar-Apr;187(2):116-27. doi: 10.1007/s00408-008-9129-z. Epub 2008 Dec 13.

PMID:
19083056
41.

Endothelial pathomechanisms in acute lung injury.

Maniatis NA, Kotanidou A, Catravas JD, Orfanos SE.

Vascul Pharmacol. 2008 Oct-Dec;49(4-6):119-33. doi: 10.1016/j.vph.2008.06.009. Epub 2008 Jul 29. Review.

PMID:
18722553
42.

Endothelial nitric oxide (NO) and its pathophysiologic regulation.

Chatterjee A, Black SM, Catravas JD.

Vascul Pharmacol. 2008 Oct-Dec;49(4-6):134-40. doi: 10.1016/j.vph.2008.06.008. Epub 2008 Jul 20. Review. Erratum in: Vascul Pharmacol. 2009 May-Jun;50(5-6):208. Black, Stephen M [added].

43.

Pulmonary capillary endothelial metabolic function in chronic thromboembolic pulmonary hypertension.

Orfanos SE, Hirsch AM, Giovinazzo M, Armaganidis A, Catravas JD, Langleben D.

J Thromb Haemost. 2008 Aug;6(8):1275-80. doi: 10.1111/j.1538-7836.2008.03046.x. Epub 2008 Jun 4.

44.

Heat shock protein 90 inhibitors protect and restore pulmonary endothelial barrier function.

Antonov A, Snead C, Gorshkov B, Antonova GN, Verin AD, Catravas JD.

Am J Respir Cell Mol Biol. 2008 Nov;39(5):551-9. doi: 10.1165/rcmb.2007-0324OC. Epub 2008 May 12.

45.

Pulmonary capillary endothelial metabolic dysfunction: severity in pulmonary arterial hypertension related to connective tissue disease versus idiopathic pulmonary arterial hypertension.

Langleben D, Orfanos SE, Giovinazzo M, Hirsch A, Baron M, Senécal JL, Armaganidis A, Catravas JD.

Arthritis Rheum. 2008 Apr;58(4):1156-64. doi: 10.1002/art.23405.

46.

Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability.

Chatterjee A, Snead C, Yetik-Anacak G, Antonova G, Zeng J, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L755-63. doi: 10.1152/ajplung.00350.2007. Epub 2008 Feb 1.

47.

Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.

Xia T, Dimitropoulou C, Zeng J, Antonova GN, Snead C, Venema RC, Fulton D, Qian S, Patterson C, Papapetropoulos A, Catravas JD.

Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H3080-7. Epub 2007 Sep 14.

48.

Functional significance of hsp90 complexes with NOS and sGC in endothelial cells.

Antonova G, Lichtenbeld H, Xia T, Chatterjee A, Dimitropoulou C, Catravas JD.

Clin Hemorheol Microcirc. 2007;37(1-2):19-35.

PMID:
17641392
49.

Estrogen as a new therapeutic target for asthma and chronic obstructive pulmonary disease.

Dimitropoulou C, Drakopanagiotakis F, Catravas JD.

Drug News Perspect. 2007 May;20(4):241-52. Review.

PMID:
17637937
50.

Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.

Chatterjee A, Dimitropoulou C, Drakopanayiotakis F, Antonova G, Snead C, Cannon J, Venema RC, Catravas JD.

Am J Respir Crit Care Med. 2007 Oct 1;176(7):667-75. Epub 2007 Jul 5.

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