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Items: 20


Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection.

Savaryn JP, Toby TK, Catherman AD, Fellers RT, LeDuc RD, Thomas PM, Friedewald JJ, Salomon DR, Abecassis MM, Kelleher NL.

Proteomics. 2016 Jul;16(14):2048-58. doi: 10.1002/pmic.201600008.


CN-GELFrEE - Clear Native Gel-eluted Liquid Fraction Entrapment Electrophoresis.

Melani RD, Seckler HS, Skinner OS, Do Vale LH, Catherman AD, Havugimana PC, Valle de Sousa M, Domont GB, Kelleher NL, Compton PD.

J Vis Exp. 2016 Feb 29;(108):53597. doi: 10.3791/53597.


Defining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multidimensional Mass Spectrometry-Based Platform.

Ye H, Wang J, Zhang Z, Jia C, Schmerberg C, Catherman AD, Thomas PM, Kelleher NL, Li L.

J Proteome Res. 2015 Nov 6;14(11):4776-91. doi: 10.1021/acs.jproteome.5b00627. Epub 2015 Oct 5.


Native GELFrEE: a new separation technique for biomolecular assemblies.

Skinner OS, Do Vale LH, Catherman AD, Havugimana PC, de Sousa MV, Compton PD, Kelleher NL.

Anal Chem. 2015 Mar 3;87(5):3032-8. doi: 10.1021/ac504678d. Epub 2015 Feb 20.


Fragmentation of integral membrane proteins in the gas phase.

Skinner OS, Catherman AD, Early BP, Thomas PM, Compton PD, Kelleher NL.

Anal Chem. 2014 May 6;86(9):4627-34. doi: 10.1021/ac500864w. Epub 2014 Apr 17.


Top Down proteomics: facts and perspectives.

Catherman AD, Skinner OS, Kelleher NL.

Biochem Biophys Res Commun. 2014 Mar 21;445(4):683-93. doi: 10.1016/j.bbrc.2014.02.041. Epub 2014 Feb 17. Review.


Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.

Catherman AD, Durbin KR, Ahlf DR, Early BP, Fellers RT, Tran JC, Thomas PM, Kelleher NL.

Mol Cell Proteomics. 2013 Dec;12(12):3465-73. doi: 10.1074/mcp.M113.030114. Epub 2013 Sep 10.


The emergence of top-down proteomics in clinical research.

Savaryn JP, Catherman AD, Thomas PM, Abecassis MM, Kelleher NL.

Genome Med. 2013 Jun 27;5(6):53. doi: 10.1186/gm457. eCollection 2013.


Top down proteomics of human membrane proteins from enriched mitochondrial fractions.

Catherman AD, Li M, Tran JC, Durbin KR, Compton PD, Early BP, Thomas PM, Kelleher NL.

Anal Chem. 2013 Feb 5;85(3):1880-8. doi: 10.1021/ac3031527. Epub 2013 Jan 23.


High-definition de novo sequencing of crustacean hyperglycemic hormone (CHH)-family neuropeptides.

Jia C, Hui L, Cao W, Lietz CB, Jiang X, Chen R, Catherman AD, Thomas PM, Ge Y, Kelleher NL, Li L.

Mol Cell Proteomics. 2012 Dec;11(12):1951-64. doi: 10.1074/mcp.M112.020537. Epub 2012 Oct 1.


Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa.

Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Lee JE, Kellie JF, Kelleher NL, Hendrickson CL, Marshall AG.

Anal Chem. 2012 Mar 6;84(5):2111-7. doi: 10.1021/ac202651v. Epub 2012 Feb 22.


Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry.

Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE 2nd, Thomas PM, Kelleher NL.

Anal Chem. 2012 Jan 3;84(1):209-15. doi: 10.1021/ac202384v. Epub 2011 Dec 14.


Mapping intact protein isoforms in discovery mode using top-down proteomics.

Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL.

Nature. 2011 Oct 30;480(7376):254-8. doi: 10.1038/nature10575.


Analysis of intact protein isoforms by mass spectrometry.

Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Kelleher NL.

J Biol Chem. 2011 Jul 22;286(29):25451-8. doi: 10.1074/jbc.R111.239442. Epub 2011 Jun 1. Review.


Investigating the effects of conductivity on zone overlap with EMMA: computer simulation and experiment.

Stahl JW, Catherman AD, Sampath RK, Seneviratne CA, Strein TG.

Electrophoresis. 2011 Jun;32(12):1492-9. doi: 10.1002/elps.201000451. Epub 2011 May 11.


Intact mass detection, interpretation, and visualization to automate Top-Down proteomics on a large scale.

Durbin KR, Tran JC, Zamdborg L, Sweet SM, Catherman AD, Lee JE, Li M, Kellie JF, Kelleher NL.

Proteomics. 2010 Oct;10(20):3589-97. doi: 10.1002/pmic.201000177.


The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput.

Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, Kelleher NL.

Mol Biosyst. 2010 Sep;6(9):1532-9. doi: 10.1039/c000896f. Epub 2010 Mar 29.


Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa.

Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, Kelleher NL.

Anal Chem. 2010 Feb 15;82(4):1234-44. doi: 10.1021/ac9021083.


A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome.

Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AD, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Marshall AG, Kelleher NL.

J Am Soc Mass Spectrom. 2009 Dec;20(12):2183-91. doi: 10.1016/j.jasms.2009.08.001. Epub 2009 Aug 12.


Determination of total antioxidant capacity of commercial beverage samples by capillary electrophoresis via inline reaction with 2,6-dichlorophenolindophenol.

Merola ET, Catherman AD, Yehl JB, Strein TG.

J Agric Food Chem. 2009 Aug 12;57(15):6518-23. doi: 10.1021/jf901214r.

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