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Items: 1 to 50 of 54

1.

ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma.

Ceballos MP, Rigalli JP, Ceré LI, Semeniuk M, Catania VA, Ruiz ML.

Curr Med Chem. 2019;26(7):1224-1250. doi: 10.2174/0929867325666180105103637. Review.

PMID:
29303075
2.

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.

Lambertucci F, Motiño O, Villar S, Rigalli JP, de Luján Alvarez M, Catania VA, Martín-Sanz P, Carnovale CE, Quiroga AD, Francés DE, Ronco MT.

Toxicol Appl Pharmacol. 2017 Jan 15;315:12-22. doi: 10.1016/j.taap.2016.11.015. Epub 2016 Nov 27.

PMID:
27899278
3.

Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole.

Perdomo VG, Rigalli JP, Luquita MG, Pellegrino JM, Ruiz ML, Catania VA.

Mem Inst Oswaldo Cruz. 2016 Nov;111(11):707-711. doi: 10.1590/0074-02760160080. Epub 2016 Oct 24.

4.

The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).

Rigalli JP, Perdomo VG, Ciriaci N, Francés DE, Ronco MT, Bataille AM, Ghanem CI, Ruiz ML, Manautou JE, Catania VA.

Toxicol Appl Pharmacol. 2016 Aug 1;304:90-8. doi: 10.1016/j.taap.2016.05.007. Epub 2016 May 12.

5.

Modulation of Expression and Activity of ABC Transporters by the Phytoestrogen Genistein. Impact on Drug Disposition.

Rigalli JP, Ciriaci N, Mottino AD, Catania VA, Ruiz ML.

Curr Med Chem. 2016;23(13):1370-89. Review.

PMID:
27048380
6.

The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters.

Rigalli JP, Tocchetti GN, Arana MR, Villanueva SS, Catania VA, Theile D, Ruiz ML, Weiss J.

Cancer Lett. 2016 Jun 28;376(1):165-72. doi: 10.1016/j.canlet.2016.03.040. Epub 2016 Mar 24.

PMID:
27033456
7.

Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity.

Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.

PLoS One. 2015 Mar 17;10(3):e0119502. doi: 10.1371/journal.pone.0119502. eCollection 2015.

8.

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.

Arias A, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Perdomo VG, Vore M, Catania VA, Mottino AD.

Toxicology. 2014 Jun 5;320:46-55. doi: 10.1016/j.tox.2014.03.007. Epub 2014 Mar 28.

PMID:
24685904
9.

Hormonal regulation of hepatic drug biotransformation and transport systems.

Ruiz ML, Mottino AD, Catania VA, Vore M.

Compr Physiol. 2013 Oct;3(4):1721-40. doi: 10.1002/cphy.c130018. Review.

PMID:
24265243
10.

Modulation of biotransformation systems and ABC transporters by benznidazole in rats.

Perdomo VG, Rigalli JP, Villanueva SS, Ruiz ML, Luquita MG, Echenique CG, Catania VA.

Antimicrob Agents Chemother. 2013 Oct;57(10):4894-902. doi: 10.1128/AAC.02531-12. Epub 2013 Jul 22.

11.

Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1.

Ruiz ML, Rigalli JP, Arias A, Villanueva SS, Banchio C, Vore M, Mottino AD, Catania VA.

Biochem Pharmacol. 2013 Aug 1;86(3):401-9. doi: 10.1016/j.bcp.2013.05.025. Epub 2013 Jun 6.

PMID:
23747343
12.

Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor.

Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.

PLoS Negl Trop Dis. 2012;6(12):e1951. doi: 10.1371/journal.pntd.0001951. Epub 2012 Dec 13.

13.

Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor.

Ruiz ML, Rigalli JP, Arias A, Villanueva S, Banchio C, Vore M, Mottino AD, Catania VA.

Drug Metab Dispos. 2013 Feb;41(2):275-80. doi: 10.1124/dmd.112.047357. Epub 2012 Oct 17.

14.

Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2012 Jul;40(7):1252-8. doi: 10.1124/dmd.111.044339. Epub 2012 Mar 27.

15.

Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.

Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

Toxicology. 2011 Jul 11;285(1-2):18-24. doi: 10.1016/j.tox.2011.03.015. Epub 2011 Apr 1.

PMID:
21459122
16.

Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat.

Villanueva SS, Arias A, Ruiz ML, Rigalli JP, Pellegrino JM, Vore M, Catania VA, Mottino AD.

J Pharmacol Exp Ther. 2010 Nov;335(2):332-41. doi: 10.1124/jpet.110.171041. Epub 2010 Aug 18.

PMID:
20719938
17.

Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.

Ruiz ML, Villanueva SS, Luquita MG, Pellegrino JM, Rigalli JP, Arias A, Sánchez Pozzi EJ, Mottino AD, Catania VA.

Eur J Pharmacol. 2009 Nov 25;623(1-3):103-6. doi: 10.1016/j.ejphar.2009.09.014. Epub 2009 Sep 17.

PMID:
19766108
18.

Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose.

Ghanem CI, Ruiz ML, Villanueva SS, Luquita M, Llesuy S, Catania VA, Bengochea LA, Mottino AD.

Biochem Pharmacol. 2009 May 15;77(10):1621-8. doi: 10.1016/j.bcp.2009.02.006. Epub 2009 Feb 23.

PMID:
19426699
19.

Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens.

Arias A, Villanueva SS, Ruiz ML, Luquita MG, Veggi LM, Pellegrino JM, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2009 Jun;37(6):1277-85. doi: 10.1124/dmd.108.025643. Epub 2009 Mar 19.

PMID:
19299525
20.

Hepatic drug transporters and nuclear receptors: regulation by therapeutic agents.

Mottino AD, Catania VA.

World J Gastroenterol. 2008 Dec 14;14(46):7068-74. Review.

21.

Dapsone induces oxidative stress and impairs antioxidant defenses in rat liver.

Veggi LM, Pretto L, Ochoa EJ, Catania VA, Luquita MG, Taborda DR, Sánchez Pozzi EJ, Ikushiro S, Coleman MD, Roma MG, Mottino AD.

Life Sci. 2008 Aug 1;83(5-6):155-63. doi: 10.1016/j.lfs.2008.05.016. Epub 2008 Jun 18.

PMID:
18602405
22.

Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats.

Villanueva SS, Ruiz ML, Ghanem CI, Luquita MG, Catania VA, Mottino AD.

Drug Metab Dispos. 2008 Mar;36(3):475-80. Epub 2007 Dec 20.

PMID:
18096675
23.

Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2.

Ruiz ML, Villanueva SS, Luquita MG, Ikushiro S, Mottino AD, Catania VA.

Drug Metab Dispos. 2007 Nov;35(11):2060-6. Epub 2007 Aug 8.

PMID:
17686906
24.

Induction of rat intestinal P-glycoprotein by spironolactone and its effect on absorption of orally administered digoxin.

Ghanem CI, Gómez PC, Arana MC, Perassolo M, Delli Carpini G, Luquita MG, Veggi LM, Catania VA, Bengochea LA, Mottino AD.

J Pharmacol Exp Ther. 2006 Sep;318(3):1146-52. Epub 2006 Jun 1.

PMID:
16740618
25.

Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats.

Villanueva SS, Ruiz ML, Soroka CJ, Cai SY, Luquita MG, Torres AM, Sánchez Pozzi EJ, Pellegrino JM, Boyer JL, Catania VA, Mottino AD.

Drug Metab Dispos. 2006 Aug;34(8):1301-9. Epub 2006 May 5.

PMID:
16679389
26.

Galactosamine prevents ethinylestradiol-induced cholestasis.

Crocenzi FA, Pellegrino JM, Catania VA, Luquita MG, Roma MG, Mottino AD, Pozzi EJ.

Drug Metab Dispos. 2006 Jun;34(6):993-7. Epub 2006 Mar 22.

PMID:
16554370
27.

Ethynylestradiol increases expression and activity of rat liver MRP3.

Ruiz ML, Villanueva SS, Luquita MG, Vore M, Mottino AD, Catania VA.

Drug Metab Dispos. 2006 Jun;34(6):1030-4. Epub 2006 Mar 22.

PMID:
16554369
28.

Shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats.

Ghanem CI, Ruiz ML, Villanueva SS, Luquita MG, Catania VA, Jones B, Bengochea LA, Vore M, Mottino AD.

J Pharmacol Exp Ther. 2005 Dec;315(3):987-95. Epub 2005 Aug 18.

PMID:
16109740
29.

Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.

Crocenzi FA, D'Andrea V, Catania VA, Luquita MG, Pellegrino JM, Ochoa JE, Mottino AD, Sánchez Pozzi EJ.

Drug Metab Dispos. 2005 Jul;33(7):888-91. Epub 2005 Apr 20.

PMID:
15843489
30.

Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

Ruiz ML, Villanueva SS, Luquita MG, Sánchez-Pozzi EJ, Crocenzi FA, Pellegrino JM, Ochoa JE, Vore M, Mottino AD, Catania VA.

Biochem Pharmacol. 2005 Feb 1;69(3):531-9. Epub 2004 Dec 15.

PMID:
15652244
31.

Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats.

Villanueva SS, Ruiz ML, Luquita MG, Sánchez Pozzi EJ, Catania VA, Mottino AD.

Toxicol Sci. 2005 Mar;84(1):4-11. Epub 2004 Dec 8.

PMID:
15590889
32.

Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein.

Ghanem CI, Gómez PC, Arana MC, Perassolo M, Ruiz ML, Villanueva SS, Ochoa EJ, Catania VA, Bengochea LA, Mottino AD.

Biochem Pharmacol. 2004 Aug 15;68(4):791-8.

PMID:
15276087
33.

Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2.

Catania VA, Sánchez Pozzi EJ, Luquita MG, Ruiz ML, Villanueva SS, Jones B, Mottino AD.

Ann Hepatol. 2004 Jan-Mar;3(1):11-7. Review.

34.

Effect of spironolactone on the expression of rat hepatic UDP-glucuronosyltransferase.

Catania VA, Luquita MG, Sánchez Pozzi EJ, Ikushiro S, Emi Y, Iyanagi T, Mottino AD.

Biochem Pharmacol. 2003 Jul 1;66(1):171-7.

PMID:
12818378
35.

Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis.

Sánchez Pozzi EJ, Crocenzi FA, Pellegrino JM, Catania VA, Luquita MG, Roma MG, Rodríguez Garay EA, Mottino AD.

J Pharmacol Exp Ther. 2003 Jul;306(1):279-86. Epub 2003 Mar 27.

PMID:
12663690
36.

Increased expression of ileal apical sodium-dependent bile acid transporter in postpartum rats.

Mottino AD, Hoffman T, Dawson PA, Luquita MG, Monti JA, Sánchez Pozzi EJ, Catania VA, Cao J, Vore M.

Am J Physiol Gastrointest Liver Physiol. 2002 Jan;282(1):G41-50.

37.

Molecular basis of perinatal changes in UDP-glucuronosyltransferase activity in maternal rat liver.

Luquita MG, Catania VA, Pozzi EJ, Veggi LM, Hoffman T, Pellegrino JM, Ikushiro Si, Emi Y, Iyanagi T, Vore M, Mottino AD.

J Pharmacol Exp Ther. 2001 Jul;298(1):49-56.

PMID:
11408524
38.
39.

Induction of phase II biotransformation reactions in rat jejunum during lactation. Possible involvement of prolactin.

Luquita MG, Catania VA, Sánchez Pozzi EJ, Vore M, Veggi LM, Pellegrino JM, Mottino AD.

Biochim Biophys Acta. 1999 Oct 18;1472(1-2):82-92.

PMID:
10572928
40.

Prolactin increases the hepatic content of mu-class subunits of glutathione S-transferase in the rat.

Luquita MG, Catania VA, Sánchez-Pozzi EJ, Vore M, Mottino AD.

Drug Metab Dispos. 1999 Jan;27(1):122-4.

PMID:
9884320
41.

Differential induction of glutathione S-transferase subunits by spironolactone in rat liver, jejunum and colon.

Catania VA, Luquita MG, Sánchez Pozzi EJ, Mottino AD.

Life Sci. 1998;63(26):2285-93.

PMID:
9877218
42.

Enhancement of intestinal UDP-glucuronosyltranferase activity in partially hepatectomized rats.

Catania VA, Luquita MG, Sánchez Pozzi EJ, Mottino AD.

Biochim Biophys Acta. 1998 May 8;1380(3):345-53.

PMID:
9555089
43.

Ovine prolactin increases hepatic UDP-glucuronosyltransferase activity in ovariectomized rats.

Luquita MG, Catania VA, Sánchez-Pozzi EJ, Mottino AD.

J Pharmacol Exp Ther. 1996 Aug;278(2):921-5.

PMID:
8768748
44.

Enhancement of intestinal bilirubin UDP-glucuronosyltransferase activity by modification of microsomal lipid composition.

Sánchez-Pozzi EJ, Catania VA, Rodríguez-Garay EA, Mottino AD.

Biochim Biophys Acta. 1995 Dec 14;1245(3):293-8.

PMID:
8541303
45.

Gender-related differences in the amount and functional state of rat liver UDP-glucuronosyltransferase.

Catania VA, Dannenberg AJ, Luquita MG, Sánchez Pozzi EJ, Tucker JK, Yang EK, Mottino AD.

Biochem Pharmacol. 1995 Aug 8;50(4):509-14.

PMID:
7646557
46.

Enhancement of cytosolic and microsomal glutathione S-transferase activities in liver and small intestine from female rats during lactation.

Luquita MG, Catania VA, Sánchez Pozzi EJ, Mottino AD.

Pharmacol Toxicol. 1995 Jan;76(1):72-5.

PMID:
7753762
47.

Effect of oral administration of ursodeoxycholic acid on rat hepatic and intestinal UDP-glucuronosyltransferase.

Sánchez Pozzi EJ, Catania VA, Luquita MG, Roma MG, Rodríguez Garay EA, Mottino AD.

Can J Physiol Pharmacol. 1994 Nov;72(11):1265-71.

PMID:
7767865
48.

Analysis of p-nitrophenol glucuronidation in hepatic microsomes from lactating rats.

Luquita MG, Sánchez Pozzi EJ, Catania VA, Mottino AD.

Biochem Pharmacol. 1994 Mar 29;47(7):1179-85.

PMID:
8161347
49.

Inhibition of rat liver microsomal bilirubin UDP-glucuronosyltransferase by ursodeoxycholic acid.

Sánchez Pozzi EJ, Luquita MG, Catania VA, Rodríguez Garay EA, Mottino AD.

Life Sci. 1994;55(2):111-20.

PMID:
8015354
50.

Absence of hepatic p-nitrophenol UDP-glucuronosyltransferase induction by spironolactone in male rats: possible involvement of testosterone.

Catania VA, Luquita MG, Sánchez Pozzi EJ, Ferri AM, Mottino AD.

Can J Physiol Pharmacol. 1992 Nov;70(11):1502-7.

PMID:
1296864

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