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Items: 1 to 20 of 41


Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration.

Hetmanski JHR, de Belly H, Busnelli I, Waring T, Nair RV, Sokleva V, Dobre O, Cameron A, Gauthier N, Lamaze C, Swift J, Del Campo A, Starborg T, Zech T, Goetz JG, Paluch EK, Schwartz JM, Caswell PT.

Dev Cell. 2019 Nov 18;51(4):460-475.e10. doi: 10.1016/j.devcel.2019.09.006. Epub 2019 Oct 10.


Control of adhesion and protrusion in cell migration by Rho GTPases.

Warner H, Wilson BJ, Caswell PT.

Curr Opin Cell Biol. 2019 Feb;56:64-70. doi: 10.1016/ Epub 2018 Oct 3. Review.


Modeling Rho GTPase Dynamics Using Boolean Logic.

Hetmanski JHR, Schwartz JM, Caswell PT.

Methods Mol Biol. 2018;1821:37-46. doi: 10.1007/978-1-4939-8612-5_3.


Vesicle trafficking pathways that direct cell migration in 3D matrices and in vivo.

Wilson BJ, Allen JL, Caswell PT.

Traffic. 2018 Dec;19(12):899-909. doi: 10.1111/tra.12605. Epub 2018 Sep 10. Review.


Actin-Based Cell Protrusion in a 3D Matrix.

Caswell PT, Zech T.

Trends Cell Biol. 2018 Oct;28(10):823-834. doi: 10.1016/j.tcb.2018.06.003. Epub 2018 Jun 30. Review.


Correction to: JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells.

Caswell PT, Dickens M.

Mol Cell Biochem. 2018 Jul;444(1-2):15. doi: 10.1007/s11010-018-3354-4.


JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells.

Caswell PT, Dickens M.

Mol Cell Biochem. 2018 Jul;444(1-2):1-13. doi: 10.1007/s11010-017-3222-7. Epub 2017 Nov 20. Erratum in: Mol Cell Biochem. 2018 May 3;:.


Extracellular matrix promotes clathrin-dependent endocytosis of prolactin and STAT5 activation in differentiating mammary epithelial cells.

Bridgewater RE, Streuli CH, Caswell PT.

Sci Rep. 2017 Jul 4;7(1):4572. doi: 10.1038/s41598-017-04783-6.


Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.

Gundry C, Marco S, Rainero E, Miller B, Dornier E, Mitchell L, Caswell PT, Campbell AD, Hogeweg A, Sansom OJ, Morton JP, Norman JC.

Nat Commun. 2017 Mar 15;8:14646. doi: 10.1038/ncomms14646.


Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion.

Hetmanski JH, Schwartz JM, Caswell PT.

Biochem Soc Trans. 2016 Dec 15;44(6):1695-1700.


Rationalizing Rac1 and RhoA GTPase signaling: A mathematical approach.

Hetmanski JHR, Schwartz JM, Caswell PT.

Small GTPases. 2018 May 4;9(3):224-229. doi: 10.1080/21541248.2016.1218406. Epub 2016 Aug 30.


A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion.

Hetmanski JH, Zindy E, Schwartz JM, Caswell PT.

PLoS Comput Biol. 2016 May 3;12(5):e1004909. doi: 10.1371/journal.pcbi.1004909. eCollection 2016 May.


Persistent cell migration and adhesion rely on retrograde transport of β(1) integrin.

Shafaq-Zadah M, Gomes-Santos CS, Bardin S, Maiuri P, Maurin M, Iranzo J, Gautreau A, Lamaze C, Caswell P, Goud B, Johannes L.

Nat Cell Biol. 2016 Jan;18(1):54-64. doi: 10.1038/ncb3287. Epub 2015 Dec 7.


Endocytic Trafficking of Integrins in Cell Migration.

Paul NR, Jacquemet G, Caswell PT.

Curr Biol. 2015 Nov 16;25(22):R1092-105. doi: 10.1016/j.cub.2015.09.049. Review.


α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.

Paul NR, Allen JL, Chapman A, Morlan-Mairal M, Zindy E, Jacquemet G, Fernandez del Ama L, Ferizovic N, Green DM, Howe JD, Ehler E, Hurlstone A, Caswell PT.

J Cell Biol. 2015 Sep 14;210(6):1013-31. doi: 10.1083/jcb.201502040.


Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration.

Rainero E, Howe JD, Caswell PT, Jamieson NB, Anderson K, Critchley DR, Machesky L, Norman JC.

Cell Rep. 2015 Jan 20;10(3):398-413. doi: 10.1016/j.celrep.2014.12.037. Epub 2015 Jan 15.


Mutant p53 regulates Dicer through p63-dependent and -independent mechanisms to promote an invasive phenotype.

Muller PA, Trinidad AG, Caswell PT, Norman JC, Vousden KH.

J Biol Chem. 2014 Jan 3;289(1):122-32. doi: 10.1074/jbc.M113.502138. Epub 2013 Nov 12.


RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex.

Jacquemet G, Green DM, Bridgewater RE, von Kriegsheim A, Humphries MJ, Norman JC, Caswell PT.

J Cell Biol. 2013 Sep 16;202(6):917-35. doi: 10.1083/jcb.201302041. Epub 2013 Sep 9.


Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.

Jacquemet G, Morgan MR, Byron A, Humphries JD, Choi CK, Chen CS, Caswell PT, Humphries MJ.

J Cell Sci. 2013 Sep 15;126(Pt 18):4121-35. doi: 10.1242/jcs.121988. Epub 2013 Jul 10.


Role of adhesion receptor trafficking in 3D cell migration.

Jacquemet G, Humphries MJ, Caswell PT.

Curr Opin Cell Biol. 2013 Oct;25(5):627-32. doi: 10.1016/ Epub 2013 Jun 21. Review.

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