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Items: 1 to 50 of 270

1.

Imbalance between Omega-6 and Omega-3 Polyunsaturated Fatty Acids in Early Pregnancy Is Predictive of Postpartum Depression in a Belgian Cohort.

Hoge A, Tabar V, Donneau AF, Dardenne N, Degée S, Timmermans M, Nisolle M, Guillaume M, Castronovo V.

Nutrients. 2019 Apr 18;11(4). pii: E876. doi: 10.3390/nu11040876.

2.

Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis.

Rademaker G, Costanza B, Bellier J, Herfs M, Peiffer R, Agirman F, Maloujahmoum N, Habraken Y, Delvenne P, Bellahcène A, Castronovo V, Peulen O.

Oncogenesis. 2019 Mar 8;8(3):21. doi: 10.1038/s41389-019-0130-6.

3.

Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration.

Costanza B, Rademaker G, Tiamiou A, De Tullio P, Leenders J, Blomme A, Bellier J, Bianchi E, Turtoi A, Delvenne P, Bellahcène A, Peulen O, Castronovo V.

Int J Cancer. 2019 Mar 4. doi: 10.1002/ijc.32247. [Epub ahead of print]

PMID:
30834519
4.

Importance of n-3 PUFA consumption during pregnancy: perception discrepancies between pregnant women and gynaecologists-obstetricians in Belgium.

Hoge A, Bernardy F, Donneau AF, Dardenne N, Degée S, Nisolle M, Guillaume M, Castronovo V.

Public Health Nutr. 2019 May;22(7):1259-1268. doi: 10.1017/S1368980019000089. Epub 2019 Feb 20.

PMID:
30782241
5.

The paradox of paradoxical insomnia: A theoretical review towards a unifying evidence-based definition.

Castelnovo A, Ferri R, Punjabi NM, Castronovo V, Garbazza C, Zucconi M, Ferini-Strambi L, Manconi M.

Sleep Med Rev. 2019 Apr;44:70-82. doi: 10.1016/j.smrv.2018.12.007. Epub 2018 Dec 25. Review.

PMID:
30731262
6.

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.

Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A.

Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7.

7.

Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer.

Bellier J, Nokin MJ, Lardé E, Karoyan P, Peulen O, Castronovo V, Bellahcène A.

Diabetes Res Clin Pract. 2019 Feb;148:200-211. doi: 10.1016/j.diabres.2019.01.002. Epub 2019 Jan 18. Review.

PMID:
30664892
8.

Insomnia Patients With Subjective Short Total Sleep Time Have a Boosted Response to Cognitive Behavioral Therapy for Insomnia Despite Residual Symptoms.

Galbiati A, Sforza M, Poletti M, Verga L, Zucconi M, Ferini-Strambi L, Castronovo V.

Behav Sleep Med. 2018 Nov 23:1-10. doi: 10.1080/15402002.2018.1545650. [Epub ahead of print]

PMID:
30468399
9.

Sleep apnea: Altered brain connectivity underlying a working-memory challenge.

Canessa N, Castronovo V, Cappa SF, Marelli S, Iadanza A, Falini A, Ferini-Strambi L.

Neuroimage Clin. 2018 Apr 3;19:56-65. doi: 10.1016/j.nicl.2018.03.036. eCollection 2018.

10.

Human peroxidasin 1 promotes angiogenesis through ERK1/2, Akt, and FAK pathways.

Medfai H, Khalil A, Rousseau A, Nuyens V, Paumann-Page M, Sevcnikar B, Furtmüller PG, Obinger C, Moguilevsky N, Peulen O, Herfs M, Castronovo V, Amri M, Van Antwerpen P, Vanhamme L, Zouaoui Boudjeltia K.

Cardiovasc Res. 2019 Feb 1;115(2):463-475. doi: 10.1093/cvr/cvy179.

PMID:
29982533
11.

Long-term clinical effect of group cognitive behavioral therapy for insomnia: a case series study.

Castronovo V, Galbiati A, Sforza M, Poletti M, Giarolli L, Kuo T, Zucconi M, Manconi M, Hensley M, Morin C, Ferini-Strambi L.

Sleep Med. 2018 Jul;47:54-59. doi: 10.1016/j.sleep.2018.03.017. Epub 2018 Apr 11.

PMID:
29753926
12.

Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression.

Brohée L, Peulen O, Nusgens B, Castronovo V, Thiry M, Colige AC, Deroanne CF.

Sci Rep. 2018 May 4;8(1):7050. doi: 10.1038/s41598-018-25340-9.

13.

Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.

Rademaker G, Hennequière V, Brohée L, Nokin MJ, Lovinfosse P, Durieux F, Gofflot S, Bellier J, Costanza B, Herfs M, Peiffer R, Bettendorff L, Deroanne C, Thiry M, Delvenne P, Hustinx R, Bellahcène A, Castronovo V, Peulen O.

Oncogene. 2018 Aug;37(32):4398-4412. doi: 10.1038/s41388-018-0287-z. Epub 2018 May 3.

14.

Low omega-3 index values and monounsaturated fatty acid levels in early pregnancy: an analysis of maternal erythrocytes fatty acids.

Hoge A, Bernardy F, Donneau AF, Dardenne N, Degée S, Timmermans M, Nisolle M, Guillaume M, Castronovo V.

Lipids Health Dis. 2018 Apr 2;17(1):63. doi: 10.1186/s12944-018-0716-6.

15.

Innovative methodology for the identification of soluble biomarkers in fresh tissues.

Costanza B, Turtoi A, Bellahcène A, Hirano T, Peulen O, Blomme A, Hennequière V, Mutijima E, Boniver J, Meuwis MA, Josse C, Koopmansch B, Segers K, Yokobori T, Fahmy K, Thiry M, Coimbra C, Garbacki N, Colige A, Baiwir D, Bours V, Louis E, Detry O, Delvenne P, Nishiyama M, Castronovo V.

Oncotarget. 2018 Jan 31;9(12):10665-10680. doi: 10.18632/oncotarget.24366. eCollection 2018 Feb 13.

16.

Innovative methods for biomarker discovery in the evaluation and development of cancer precision therapies.

Umelo IA, Costanza B, Castronovo V.

Cancer Metastasis Rev. 2018 Mar;37(1):125-145. doi: 10.1007/s10555-017-9710-0. Review.

17.

Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.

Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15.

PMID:
29242606
18.

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death.

Nokin MJ, Durieux F, Bellier J, Peulen O, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, Castronovo V, Bellahcène A.

Sci Rep. 2017 Sep 15;7(1):11722. doi: 10.1038/s41598-017-12119-7.

19.

Development and validation of the Maugeri Sleep Quality and Distress Inventory (MaSQuDI-17).

Morrone E, Sguazzin C, Bertolotti G, Giordano A, Braghiroli A, Balestroni GL, Manni R, Ferini Strambi L, Castronovo V, Zucconi M, De Carli F, Pinna E, Ottonello M, Giorgi I, Terzaghi M, Marelli S, Fanfulla F.

PLoS One. 2017 Jul 10;12(7):e0180743. doi: 10.1371/journal.pone.0180743. eCollection 2017.

20.

Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer.

Bellahcène A, Nokin MJ, Castronovo V, Schalkwijk C.

Semin Cancer Biol. 2018 Apr;49:64-74. doi: 10.1016/j.semcancer.2017.05.010. Epub 2017 Jun 7. Review.

PMID:
28600198
21.

Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition.

Hendrick E, Peixoto P, Blomme A, Polese C, Matheus N, Cimino J, Frère A, Mouithys-Mickalad A, Serteyn D, Bettendorff L, Elmoualij B, De Tullio P, Eppe G, Dequiedt F, Castronovo V, Mottet D.

Oncogene. 2017 Aug 24;36(34):4859-4874. doi: 10.1038/onc.2017.103. Epub 2017 Apr 17.

22.

Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.

Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A.

Int J Mol Sci. 2017 Jan 21;18(1). pii: E213. doi: 10.3390/ijms18010213.

23.

Stromal Modulators of TGF-β in Cancer.

Costanza B, Umelo IA, Bellier J, Castronovo V, Turtoi A.

J Clin Med. 2017 Jan 6;6(1). pii: E7. doi: 10.3390/jcm6010007. Review.

24.

[Asporin: the protective wall against triple-negative breast cancer].

Blomme A, Cusumano P, Peulen O, Bellahcène A, Castronovo V, Turtoi A.

Med Sci (Paris). 2016 Nov;32(11):1019-1022. doi: 10.1051/medsci/20163211020. Epub 2016 Dec 23. French. No abstract available.

25.

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes.

Blomme A, Fahmy K, Peulen O, Costanza B, Fontaine M, Struman I, Baiwir D, de Pauw E, Thiry M, Bellahcène A, Castronovo V, Turtoi A.

Oncotarget. 2016 Dec 13;7(50):83669-83683. doi: 10.18632/oncotarget.13276.

26.

Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer.

Quemener C, Baud J, Boyé K, Dubrac A, Billottet C, Soulet F, Darlot F, Dumartin L, Sire M, Grepin R, Daubon T, Rayne F, Wodrich H, Couvelard A, Pineau R, Schilling M, Castronovo V, Sue SC, Clarke K, Lomri A, Khatib AM, Hagedorn M, Prats H, Bikfalvi A.

Cancer Res. 2016 Nov 15;76(22):6507-6519. doi: 10.1158/0008-5472.CAN-15-2864. Epub 2016 Sep 9.

27.

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A.

Elife. 2016 Oct 19;5. pii: e19375. doi: 10.7554/eLife.19375.

28.

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone.

Fradet A, Bouchet M, Delliaux C, Gervais M, Kan C, Benetollo C, Pantano F, Vargas G, Bouazza L, Croset M, Bala Y, Leroy X, Rosol TJ, Rieusset J, Bellahcène A, Castronovo V, Aubin JE, Clézardin P, Duterque-Coquillaud M, Bonnelye E.

Oncotarget. 2016 Nov 22;7(47):77071-77086. doi: 10.18632/oncotarget.12787.

29.

Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer.

Blomme A, Costanza B, de Tullio P, Thiry M, Van Simaeys G, Boutry S, Doumont G, Di Valentin E, Hirano T, Yokobori T, Gofflot S, Peulen O, Bellahcène A, Sherer F, Le Goff C, Cavalier E, Mouithys-Mickalad A, Jouret F, Cusumano PG, Lifrange E, Muller RN, Goldman S, Delvenne P, De Pauw E, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2017 Apr;36(15):2116-2130. doi: 10.1038/onc.2016.369. Epub 2016 Oct 24.

PMID:
27775075
30.

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity.

Henry A, Nokin MJ, Leroi N, Lallemand F, Lambert J, Goffart N, Roncarati P, Bianchi E, Peixoto P, Blomme A, Turtoi A, Peulen O, Habraken Y, Scholtes F, Martinive P, Delvenne P, Rogister B, Castronovo V, Bellahcène A.

Oncotarget. 2016 Sep 27;7(39):63708-63721. doi: 10.18632/oncotarget.11483.

31.

Validation study of the Italian version of the Insomnia Severity Index (ISI).

Castronovo V, Galbiati A, Marelli S, Brombin C, Cugnata F, Giarolli L, Anelli MM, Rinaldi F, Ferini-Strambi L.

Neurol Sci. 2016 Sep;37(9):1517-24. doi: 10.1007/s10072-016-2620-z. Epub 2016 May 27.

PMID:
27234459
32.

HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies.

Peixoto P, Blomme A, Costanza B, Ronca R, Rezzola S, Palacios AP, Schoysman L, Boutry S, Goffart N, Peulen O, Maris P, Di Valentin E, Hennequière V, Bianchi E, Henry A, Meunier P, Rogister B, Muller RN, Delvenne P, Bellahcène A, Castronovo V, Turtoi A.

Oncogene. 2016 Aug 25;35(34):4481-94. doi: 10.1038/onc.2015.506. Epub 2016 Feb 8.

PMID:
26853466
33.

[Vitamin D anti-cancer activities: observations, doubts and certainties].

Castronovo C, Castronovo V, Nikkels A, Peulen O.

Rev Med Liege. 2015 Oct;70(10):495-500. Review. French.

34.

Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.

Maris P, Blomme A, Palacios AP, Costanza B, Bellahcène A, Bianchi E, Gofflot S, Drion P, Trombino GE, Di Valentin E, Cusumano PG, Maweja S, Jerusalem G, Delvenne P, Lifrange E, Castronovo V, Turtoi A.

PLoS Med. 2015 Sep 1;12(9):e1001871. doi: 10.1371/journal.pmed.1001871. eCollection 2015 Sep.

35.

Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer.

Fahmy K, Gonzalez A, Arafa M, Peixoto P, Bellahcène A, Turtoi A, Delvenne P, Thiry M, Castronovo V, Peulen O.

Int J Cancer. 2016 Feb 1;138(3):652-63. doi: 10.1002/ijc.29820. Epub 2015 Sep 8.

36.

Histone deacetylases and cancer-associated angiogenesis: current understanding of the biology and clinical perspectives.

Turtoi A, Peixoto P, Castronovo V, Bellahcène A.

Crit Rev Oncog. 2015;20(1-2):119-37. Review.

PMID:
25746107
37.

Targeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicity in vivo.

Lamour V, Henry A, Kroonen J, Nokin MJ, von Marschall Z, Fisher LW, Chau TL, Chariot A, Sanson M, Delattre JY, Turtoi A, Peulen O, Rogister B, Castronovo V, Bellahcène A.

Int J Cancer. 2015 Sep 1;137(5):1047-57. doi: 10.1002/ijc.29454. Epub 2015 May 21.

38.

Intratumoral heterogeneity and consequences for targeted therapies.

Turtoi A, Blomme A, Castronovo V.

Bull Cancer. 2015 Jan;102(1):17-23. doi: 10.1016/j.bulcan.2014.12.006. Epub 2015 Jan 2. Review.

39.

Accessibilome of human glioblastoma: collagen-VI-alpha-1 is a new target and a marker of poor outcome.

Turtoi A, Blomme A, Bianchi E, Maris P, Vannozzi R, Naccarato AG, Delvenne P, De Pauw E, Bevilacqua G, Castronovo V.

J Proteome Res. 2014 Dec 5;13(12):5660-9. doi: 10.1021/pr500657w. Epub 2014 Nov 3.

40.

White matter integrity in obstructive sleep apnea before and after treatment.

Castronovo V, Scifo P, Castellano A, Aloia MS, Iadanza A, Marelli S, Cappa SF, Strambi LF, Falini A.

Sleep. 2014 Sep 1;37(9):1465-75. doi: 10.5665/sleep.3994.

41.

Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes.

Chiavarina B, Nokin MJ, Durieux F, Bianchi E, Turtoi A, Peulen O, Peixoto P, Irigaray P, Uchida K, Belpomme D, Delvenne P, Castronovo V, Bellahcène A.

Oncotarget. 2014 Jul 30;5(14):5472-82.

42.
43.

ΔNp63 isoform-mediated β-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma.

Suarez-Carmona M, Hubert P, Gonzalez A, Duray A, Roncarati P, Erpicum C, Boniver J, Castronovo V, Noel A, Saussez S, Peulen O, Delvenne P, Herfs M.

Oncotarget. 2014 Apr 15;5(7):1856-68.

44.

Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum.

Bournine L, Bensalem S, Wauters JN, Iguer-Ouada M, Maiza-Benabdesselam F, Bedjou F, Castronovo V, Bellahcène A, Tits M, Frédérich M.

Int J Mol Sci. 2013 Dec 2;14(12):23533-44. doi: 10.3390/ijms141223533.

45.

[SIBLING proteins: molecular tools for tumor progression and angiogenesis].

Lamour V, Nokin MJ, Henry A, Castronovo V, Bellahcène A.

Med Sci (Paris). 2013 Nov;29(11):1018-25. doi: 10.1051/medsci/20132911019. Epub 2013 Nov 20. Review. French.

46.

A new murine model of osteoblastic/osteolytic lesions from human androgen-resistant prostate cancer.

Fradet A, Sorel H, Depalle B, Serre CM, Farlay D, Turtoi A, Bellahcene A, Follet H, Castronovo V, Clézardin P, Bonnelye E.

PLoS One. 2013 Sep 19;8(9):e75092. doi: 10.1371/journal.pone.0075092. eCollection 2013.

47.

The anti-tumor effect of HDAC inhibition in a human pancreas cancer model is significantly improved by the simultaneous inhibition of cyclooxygenase 2.

Peulen O, Gonzalez A, Peixoto P, Turtoi A, Mottet D, Delvenne P, Castronovo V.

PLoS One. 2013 Sep 11;8(9):e75102. doi: 10.1371/journal.pone.0075102. eCollection 2013.

48.

In vivo PET/CT in a human glioblastoma chicken chorioallantoic membrane model: a new tool for oncology and radiotracer development.

Warnock G, Turtoi A, Blomme A, Bretin F, Bahri MA, Lemaire C, Libert LC, Seret AE, Luxen A, Castronovo V, Plenevaux AR.

J Nucl Med. 2013 Oct;54(10):1782-8. doi: 10.2967/jnumed.112.117150. Epub 2013 Aug 22.

49.

Myoferlin is a key regulator of EGFR activity in breast cancer.

Turtoi A, Blomme A, Bellahcène A, Gilles C, Hennequière V, Peixoto P, Bianchi E, Noel A, De Pauw E, Lifrange E, Delvenne P, Castronovo V.

Cancer Res. 2013 Sep 1;73(17):5438-48. doi: 10.1158/0008-5472.CAN-13-1142. Epub 2013 Jul 17.

50.

Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells.

Bournine L, Bensalem S, Peixoto P, Gonzalez A, Maiza-Benabdesselam F, Bedjou F, Wauters JN, Tits M, Frédérich M, Castronovo V, Bellahcène A.

Phytomedicine. 2013 Oct 15;20(13):1211-8. doi: 10.1016/j.phymed.2013.06.007. Epub 2013 Jul 13.

PMID:
23860409

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