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Items: 39

1.

Neutrophils escort circulating tumour cells to enable cell cycle progression.

Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N.

Nature. 2019 Feb;566(7745):553-557. doi: 10.1038/s41586-019-0915-y. Epub 2019 Feb 6.

PMID:
30728496
2.

Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid.

Morita H, Kubo T, Rückert B, Ravindran A, Soyka MB, Rinaldi AO, Sugita K, Wawrzyniak M, Wawrzyniak P, Motomura K, Tamari M, Orimo K, Okada N, Arae K, Saito K, Altunbulakli C, Castro-Giner F, Tan G, Neumann A, Sudo K, O'Mahony L, Honda K, Nakae S, Saito H, Mjösberg J, Nilsson G, Matsumoto K, Akdis M, Akdis CA.

J Allergy Clin Immunol. 2019 Jan 22. pii: S0091-6749(19)30088-0. doi: 10.1016/j.jaci.2018.12.1018. [Epub ahead of print]

PMID:
30682454
3.

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding.

Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Aceto N.

Cell. 2019 Jan 10;176(1-2):98-112.e14. doi: 10.1016/j.cell.2018.11.046.

4.

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer.

Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, Aceto N.

Breast Cancer Res. 2018 Nov 20;20(1):141. doi: 10.1186/s13058-018-1067-y.

5.

Detection of circulating tumour cell clusters in human glioblastoma.

Krol I, Castro-Giner F, Maurer M, Gkountela S, Szczerba BM, Scherrer R, Coleman N, Carreira S, Bachmann F, Anderson S, Engelhardt M, Lane H, Evans TRJ, Plummer R, Kristeleit R, Lopez J, Aceto N.

Br J Cancer. 2018 Aug;119(4):487-491. doi: 10.1038/s41416-018-0186-7. Epub 2018 Aug 1.

PMID:
30065256
6.

Relations between epidermal barrier dysregulation and Staphylococcus species-dominated microbiome dysbiosis in patients with atopic dermatitis.

Altunbulakli C, Reiger M, Neumann AU, Garzorz-Stark N, Fleming M, Huelpuesch C, Castro-Giner F, Eyerich K, Akdis CA, Traidl-Hoffmann C.

J Allergy Clin Immunol. 2018 Nov;142(5):1643-1647.e12. doi: 10.1016/j.jaci.2018.07.005. Epub 2018 Jul 24. No abstract available.

PMID:
30048670
7.

Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients.

Bratus-Neuenschwander A, Castro-Giner F, Frank-Bertoncelj M, Aluri S, Fucentese SF, Schlapbach R, Sprott H.

Genes (Basel). 2018 Jul 4;9(7). pii: E338. doi: 10.3390/genes9070338.

8.

Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations.

Castro-Giner F, Gkountela S, Donato C, Alborelli I, Quagliata L, Ng CKY, Piscuoglio S, Aceto N.

Diagnostics (Basel). 2018 May 9;8(2). pii: E31. doi: 10.3390/diagnostics8020031. Review.

9.

Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.

MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM, Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma RA.

Sci Rep. 2018 May 8;8(1):7265. doi: 10.1038/s41598-018-24232-2.

10.

Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts.

Legrand AJ, Poletto M, Pankova D, Clementi E, Moore J, Castro-Giner F, Ryan AJ, O'Neill E, Markkanen E, Dianov GL.

Oncotarget. 2018 Feb 7;9(17):13666-13681. doi: 10.18632/oncotarget.24446. eCollection 2018 Mar 2.

11.

Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis.

Castro-Giner F, Scheidmann MC, Aceto N.

Front Med (Lausanne). 2018 Feb 19;5:34. doi: 10.3389/fmed.2018.00034. eCollection 2018. Review.

12.

Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients.

Sugita K, Steer CA, Martinez-Gonzalez I, Altunbulakli C, Morita H, Castro-Giner F, Kubo T, Wawrzyniak P, Rückert B, Sudo K, Nakae S, Matsumoto K, O'Mahony L, Akdis M, Takei F, Akdis CA.

J Allergy Clin Immunol. 2018 Jan;141(1):300-310.e11. doi: 10.1016/j.jaci.2017.02.038. Epub 2017 Apr 6.

PMID:
28392332
13.

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.

Findlay JM, Castro-Giner F, Makino S, Rayner E, Kartsonaki C, Cross W, Kovac M, Ulahannan D, Palles C, Gillies RS, MacGregor TP, Church D, Maynard ND, Buffa F, Cazier JB, Graham TA, Wang LM, Sharma RA, Middleton M, Tomlinson I.

Nat Commun. 2016 Apr 5;7:11111. doi: 10.1038/ncomms11111.

14.

The importance of p53 pathway genetics in inherited and somatic cancer genomes.

Stracquadanio G, Wang X, Wallace MD, Grawenda AM, Zhang P, Hewitt J, Zeron-Medina J, Castro-Giner F, Tomlinson IP, Goding CR, Cygan KJ, Fairbrother WG, Thomas LF, Sætrom P, Gemignani F, Landi S, Schuster-Böckler B, Bell DA, Bond GL.

Nat Rev Cancer. 2016 Apr;16(4):251-65. doi: 10.1038/nrc.2016.15. Review.

PMID:
27009395
15.

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency.

Kovac M, Blattmann C, Ribi S, Smida J, Mueller NS, Engert F, Castro-Giner F, Weischenfeldt J, Kovacova M, Krieg A, Andreou D, Tunn PU, Dürr HR, Rechl H, Schaser KD, Melcher I, Burdach S, Kulozik A, Specht K, Heinimann K, Fulda S, Bielack S, Jundt G, Tomlinson I, Korbel JO, Nathrath M, Baumhoer D.

Nat Commun. 2015 Dec 3;6:8940. doi: 10.1038/ncomms9940.

16.

The mini-driver model of polygenic cancer evolution.

Castro-Giner F, Ratcliffe P, Tomlinson I.

Nat Rev Cancer. 2015 Nov;15(11):680-5. doi: 10.1038/nrc3999. Epub 2015 Oct 12. Review.

PMID:
26456849
17.

Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer.

Sanz-Pamplona R, Lopez-Doriga A, Paré-Brunet L, Lázaro K, Bellido F, Alonso MH, Aussó S, Guinó E, Beltrán S, Castro-Giner F, Gut M, Sanjuan X, Closa A, Cordero D, Morón-Duran FD, Soriano A, Salazar R, Valle L, Moreno V.

Clin Cancer Res. 2015 Oct 15;21(20):4709-18. doi: 10.1158/1078-0432.CCR-15-0159. Epub 2015 Jun 12.

18.

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution.

Kovac M, Navas C, Horswell S, Salm M, Bardella C, Rowan A, Stares M, Castro-Giner F, Fisher R, de Bruin EC, Kovacova M, Gorman M, Makino S, Williams J, Jaeger E, Jones A, Howarth K, Larkin J, Pickering L, Gore M, Nicol DL, Hazell S, Stamp G, O'Brien T, Challacombe B, Matthews N, Phillimore B, Begum S, Rabinowitz A, Varela I, Chandra A, Horsfield C, Polson A, Tran M, Bhatt R, Terracciano L, Eppenberger-Castori S, Protheroe A, Maher E, El Bahrawy M, Fleming S, Ratcliffe P, Heinimann K, Swanton C, Tomlinson I.

Nat Commun. 2015 Mar 19;6:6336. doi: 10.1038/ncomms7336.

19.

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.

Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, Tucker A, Love S, Nanji M, deCaestecker J, Ferry D, Rathbone B, Hapeshi J, Barr H, Moayyedi P, Watson P, Zietek B, Maroo N, Gay L, Underwood T, Boulter L, McMurtry H, Monk D, Patel P, Ragunath K, Al Dulaimi D, Murray I, Koss K, Veitch A, Trudgill N, Nwokolo C, Rembacken B, Atherfold P, Green E, Ang Y, Kuipers EJ, Chow W, Paterson S, Kadri S, Beales I, Grimley C, Mullins P, Beckett C, Farrant M, Dixon A, Kelly S, Johnson M, Wajed S, Dhar A, Sawyer E, Roylance R, Onstad L, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Reid BJ, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Fitzgerald R, Whiteman DC, Risch HA, Levine DM, Vaughan TL, Verhaar AP, van den Brande J, Toxopeus EL, Spaander MC, Wijnhoven BP, van der Laan LJ, Krishnadath K, Wijmenga C, Trynka G, McManus R, Reynolds JV, O'Sullivan J, MacMathuna P, McGarrigle SA, Kelleher D, Vermeire S, Cleynen I, Bisschops R, Tomlinson I, Jankowski J.

Gastroenterology. 2015 Feb;148(2):367-78. doi: 10.1053/j.gastro.2014.10.041. Epub 2014 Nov 5.

20.

Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community Respiratory Health Survey.

Amaral AF, Ramasamy A, Castro-Giner F, Minelli C, Accordini S, Sørheim IC, Pin I, Kogevinas M, Jõgi R, Balding DJ, Norbäck D, Verlato G, Olivieri M, Probst-Hensch N, Janson C, Zock JP, Heinrich J, Jarvis DL.

Thorax. 2014 Jun;69(6):558-64. doi: 10.1136/thoraxjnl-2013-204574. Epub 2014 Mar 10.

21.

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

Balbás-Martínez C, Sagrera A, Carrillo-de-Santa-Pau E, Earl J, Márquez M, Vazquez M, Lapi E, Castro-Giner F, Beltran S, Bayés M, Carrato A, Cigudosa JC, Domínguez O, Gut M, Herranz J, Juanpere N, Kogevinas M, Langa X, López-Knowles E, Lorente JA, Lloreta J, Pisano DG, Richart L, Rico D, Salgado RN, Tardón A, Chanock S, Heath S, Valencia A, Losada A, Gut I, Malats N, Real FX.

Nat Genet. 2013 Dec;45(12):1464-9. doi: 10.1038/ng.2799. Epub 2013 Oct 13.

22.

A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.

Zeron-Medina J, Wang X, Repapi E, Campbell MR, Su D, Castro-Giner F, Davies B, Peterse EF, Sacilotto N, Walker GJ, Terzian T, Tomlinson IP, Box NF, Meinshausen N, De Val S, Bell DA, Bond GL.

Cell. 2013 Oct 10;155(2):410-22. doi: 10.1016/j.cell.2013.09.017.

23.

Lack of association of variants previously associated with anti-TNF medication response in rheumatoid arthritis patients: results from a homogeneous Greek population.

Zervou MI, Myrthianou E, Flouri I, Plant D, Chlouverakis G, Castro-Giner F, Rapsomaniki P, Barton A, Boumpas DT, Sidiropoulos P, Goulielmos GN.

PLoS One. 2013 Sep 10;8(9):e74375. doi: 10.1371/journal.pone.0074375. eCollection 2013.

24.

Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.

Zhou J, Tawk M, Tiziano FD, Veillet J, Bayes M, Nolent F, Garcia V, Servidei S, Bertini E, Castro-Giner F, Renda Y, Carpentier S, Andrieu-Abadie N, Gut I, Levade T, Topaloglu H, Melki J.

Am J Hum Genet. 2012 Jul 13;91(1):5-14. doi: 10.1016/j.ajhg.2012.05.001. Epub 2012 Jun 14.

25.

Respiratory health and endotoxin: associations and modification by CD14/-260 genotype.

Bakolis I, Doekes G, Heinrich J, Zock JP, Heederik D, Kogevinas M, Guerra S, Norbäck D, Ramasamy A, Nevalainen A, Svanes C, Chen CM, Verlato G, Olivieri M, Castro-Giner F, Jarvis D; Indoor Group of the ECRHS; Work Package 10 Group of HITEA.

Eur Respir J. 2012 Mar;39(3):573-81. doi: 10.1183/09031936.00164410. Epub 2011 Sep 1.

26.

A CD40 and an NCOA5 gene polymorphism confer susceptibility to psoriasis in a Southern European population: a case-control study.

Zervou MI, Goulielmos GN, Castro-Giner F, Boumpas DT, Tosca AD, Krueger-Krasagakis S.

Hum Immunol. 2011 Sep;72(9):761-5. doi: 10.1016/j.humimm.2011.05.014. Epub 2011 May 24.

PMID:
21645569
27.

ADRB2 Gly16Arg polymorphism, asthma control and lung function decline.

Rebordosa C, Kogevinas M, Guerra S, Castro-Giner F, Jarvis D, Cazzoletti L, Pin I, Siroux V, Wjst M, Antò JM, de Marco R, Estivill X, Corsico AG, Nielsen R, Janson C.

Eur Respir J. 2011 Nov;38(5):1029-35. doi: 10.1183/09031936.00146310. Epub 2011 Mar 24.

28.

A screening methodology based on Random Forests to improve the detection of gene-gene interactions.

De Lobel L, Geurts P, Baele G, Castro-Giner F, Kogevinas M, Van Steen K.

Eur J Hum Genet. 2010 Oct;18(10):1127-32. doi: 10.1038/ejhg.2010.48. Epub 2010 May 12.

29.

Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS).

Castro-Giner F, Künzli N, Jacquemin B, Forsberg B, de Cid R, Sunyer J, Jarvis D, Briggs D, Vienneau D, Norback D, González JR, Guerra S, Janson C, Antó JM, Wjst M, Heinrich J, Estivill X, Kogevinas M.

Environ Health Perspect. 2009 Dec;117(12):1919-24. doi: 10.1289/ehp.0900589. Epub 2009 Jul 23.

30.

The protein tyrosine phosphatase, non-receptor type 22 R620W polymorphism does not confer susceptibility to psoriasis in the genetic homogeneous population of Crete.

Zervou MI, Castro-Giner F, Sidiropoulos P, Boumpas DT, Tosca AD, Krueger-Krasagakis S.

Genet Test Mol Biomarkers. 2010 Feb;14(1):107-11. doi: 10.1089/gtmb.2009.0130.

PMID:
20039785
31.

Positionally cloned genes and age-specific effects in asthma and atopy: an international population-based cohort study (ECRHS).

Castro-Giner F, de Cid R, Gonzalez JR, Jarvis D, Heinrich J, Janson C, Omenaas ER, Matheson MC, Pin I, Antó JM, Wjst M, Estivill X, Kogevinas M.

Thorax. 2010 Feb;65(2):124-31. doi: 10.1136/thx.2009.119628. Epub 2009 Dec 8.

PMID:
19996348
32.

A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS).

Castro-Giner F, Bustamante M, Ramon González J, Kogevinas M, Jarvis D, Heinrich J, Antó JM, Wjst M, Estivill X, de Cid R.

BMC Med Genet. 2009 Dec 6;10:128. doi: 10.1186/1471-2350-10-128.

33.

STAT4 gene polymorphism is associated with psoriasis in the genetically homogeneous population of Crete, Greece.

Zervou MI, Goulielmos GN, Castro-Giner F, Tosca AD, Krueger-Krasagakis S.

Hum Immunol. 2009 Sep;70(9):738-41. doi: 10.1016/j.humimm.2009.05.008. Epub 2009 Jun 17.

PMID:
19500629
34.

GSTM1 polymorphisms modify the effect of maternal smoking during pregnancy on cognitive functioning in preschoolers.

Morales E, Sunyer J, Julvez J, Castro-Giner F, Estivill X, Torrent M, De Cid R.

Int J Epidemiol. 2009 Jun;38(3):690-7. doi: 10.1093/ije/dyp141. Epub 2009 Feb 24.

PMID:
19244254
35.

Joint effect of obesity and TNFA variability on asthma: two international cohort studies.

Castro-Giner F, Kogevinas M, Imboden M, de Cid R, Jarvis D, Mächler M, Berger W, Burney P, Franklin KA, Gonzalez JR, Heinrich J, Janson C, Omenaas E, Pin I, Rochat T, Sunyer J, Wjst M, Antó JM, Estivill X, Probst-Hensch NM.

Eur Respir J. 2009 May;33(5):1003-9. doi: 10.1183/09031936.00140608. Epub 2009 Feb 5.

36.

Influence of glutathione S-transferase polymorphisms on cognitive functioning effects induced by p,p'-DDT among preschoolers.

Morales E, Sunyer J, Castro-Giner F, Estivill X, Julvez J, Ribas-Fitó N, Torrent M, Grimalt JO, de Cid R.

Environ Health Perspect. 2008 Nov;116(11):1581-5. doi: 10.1289/ehp.11303. Epub 2008 Jul 30.

37.

TNFA -308G>A in two international population-based cohorts and risk of asthma.

Castro-Giner F, Kogevinas M, Mächler M, de Cid R, Van Steen K, Imboden M, Schindler C, Berger W, Gonzalez JR, Franklin KA, Janson C, Jarvis D, Omenaas E, Burney P, Rochat T, Estivill X, Antó JM, Wjst M, Probst-Hensch NM.

Eur Respir J. 2008 Aug;32(2):350-61. doi: 10.1183/09031936.00155607. Epub 2008 Apr 2.

38.

Air pollution, oxidative stress and dietary supplementation: a review.

Romieu I, Castro-Giner F, Kunzli N, Sunyer J.

Eur Respir J. 2008 Jan;31(1):179-97. doi: 10.1183/09031936.00128106. Review.

39.

Gene-environment interactions in asthma.

Castro-Giner F, Kauffmann F, de Cid R, Kogevinas M.

Occup Environ Med. 2006 Nov;63(11):776-86, 761. Review. No abstract available.

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