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Items: 1 to 50 of 74

1.

Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.

Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH.

Semin Arthritis Rheum. 2019 Jan 4. pii: S0049-0172(18)30651-6. doi: 10.1016/j.semarthrit.2019.01.002. [Epub ahead of print]

PMID:
30665626
2.

Disorganization of Retinal Inner Layers (DRIL) and Neuroretinal Dysfunction in Early Diabetic Retinopathy.

Joltikov KA, Sesi CA, de Castro VM, Davila JR, Anand R, Khan SM, Farbman N, Jackson GR, Johnson CA, Gardner TW.

Invest Ophthalmol Vis Sci. 2018 Nov 1;59(13):5481-5486. doi: 10.1167/iovs.18-24955.

PMID:
30452602
3.

Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.

Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Stroke. 2018 Sep;49(9):2046-2052. doi: 10.1161/STROKEAHA.118.022412.

PMID:
30354989
4.

Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study.

Can A, Rudy RF, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Neurology. 2018 Sep 18;91(12):e1175-e1181. doi: 10.1212/WNL.0000000000006200. Epub 2018 Aug 22.

PMID:
30135253
5.

Morphological Variables Associated With Ruptured Middle Cerebral Artery Aneurysms.

Zhang J, Can A, Mukundan S Jr, Steigner M, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Wang Z, Weiss ST, Du R.

Neurosurgery. 2018 May 30. doi: 10.1093/neuros/nyy213. [Epub ahead of print]

PMID:
29850834
6.

Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms.

Can A, Rudy RF, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Stroke. 2018 Jul;49(7):1747-1750. doi: 10.1161/STROKEAHA.118.020963. Epub 2018 May 29.

PMID:
29844027
7.

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.

Chen CY, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, Ruderfer DM, Murphy SN, Gainer V, Cai T, Jones I, Pato CN, Pato MT, Landén M, Sklar P, Perlis RH, Smoller JW.

Transl Psychiatry. 2018 Apr 18;8(1):86. doi: 10.1038/s41398-018-0133-7.

8.

Lipid-Lowering Agents and High HDL (High-Density Lipoprotein) Are Inversely Associated With Intracranial Aneurysm Rupture.

Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Stroke. 2018 May;49(5):1148-1154. doi: 10.1161/STROKEAHA.117.019972. Epub 2018 Apr 5.

PMID:
29622625
9.

Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records.

McCoy TH Jr, Castro VM, Hart KL, Pellegrini AM, Yu S, Cai T, Perlis RH.

Biol Psychiatry. 2018 Jun 15;83(12):1005-1011. doi: 10.1016/j.biopsych.2017.12.004. Epub 2018 Feb 26.

10.

High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records.

McCoy TH Jr, Yu S, Hart KL, Castro VM, Brown HE, Rosenquist JN, Doyle AE, Vuijk PJ, Cai T, Perlis RH.

Biol Psychiatry. 2018 Jun 15;83(12):997-1004. doi: 10.1016/j.biopsych.2018.01.011. Epub 2018 Feb 26.

11.

Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture.

Can A, Castro VM, Yu S, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Stroke. 2018 Jan;49(1):34-39. doi: 10.1161/STROKEAHA.117.019249. Epub 2017 Dec 4.

PMID:
29203688
12.

Heroin Use Is Associated with Ruptured Saccular Aneurysms.

Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Transl Stroke Res. 2018 Aug;9(4):340-346. doi: 10.1007/s12975-017-0582-y. Epub 2017 Nov 4.

PMID:
29103103
13.

Validation of Polygenic Scores for QT Interval in Clinical Populations.

Rosenberg MA, Lubitz SA, Lin H, Kosova G, Castro VM, Huang P, Ellinor PT, Perlis RH, Newton-Cheh C.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001724. doi: 10.1161/CIRCGENETICS.117.001724.

14.

Multidimensional Functional and Structural Evaluation Reveals Neuroretinal Impairment in Early Diabetic Retinopathy.

Joltikov KA, de Castro VM, Davila JR, Anand R, Khan SM, Farbman N, Jackson GR, Johnson CA, Gardner TW.

Invest Ophthalmol Vis Sci. 2017 May 1;58(6):BIO277-BIO290. doi: 10.1167/iovs.17-21863.

15.

Polygenic loading for major depression is associated with specific medical comorbidity.

McCoy TH, Castro VM, Snapper L, Hart K, Januzzi JL, Huffman JC, Perlis RH.

Transl Psychiatry. 2017 Sep 19;7(9):e1238. doi: 10.1038/tp.2017.201.

16.

Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.

McCoy TH, Castro VM, Snapper LA, Hart KL, Perlis RH.

Mol Med. 2017 Nov;23:285-294. doi: 10.2119/molmed.2017.00100. Epub 2017 Aug 31.

17.

Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation.

Can A, Castro VM, Ozdemir YH, Dagen S, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Dammers R, Weiss ST, Du R.

Neurology. 2017 Sep 26;89(13):1408-1415. doi: 10.1212/WNL.0000000000004419. Epub 2017 Aug 30.

18.

Effect of allopurinol and uric acid normalization on serum lipids hyperuricemic subjects: A systematic review with meta-analysis.

Castro VMF, Melo AC, Belo VS, Chaves VE.

Clin Biochem. 2017 Dec;50(18):1289-1297. doi: 10.1016/j.clinbiochem.2017.07.013. Epub 2017 Jul 25. Review.

PMID:
28754333
19.

Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage.

Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.

Transl Stroke Res. 2018 Feb;9(1):13-19. doi: 10.1007/s12975-017-0557-z. Epub 2017 Jul 27.

PMID:
28752411
20.

Cytochrome P450 interactions are common and consequential in Massachusetts hospital discharges.

McCoy TH, Castro VM, Cagan A, Snapper L, Roberson A, Perlis RH.

Pharmacogenomics J. 2018 Apr;18(2):347-350. doi: 10.1038/tpj.2017.30. Epub 2017 Jul 11.

PMID:
28696416
21.

Impact of antidepressant treatment during pregnancy on obstetric outcomes among women previously treated for depression: an observational cohort study.

Venkatesh KK, Castro VM, Perlis RH, Kaimal AJ.

J Perinatol. 2017 Sep;37(9):1003-1009. doi: 10.1038/jp.2017.92. Epub 2017 Jul 6.

PMID:
28682318
22.

Improving discrimination in antepartum depression screening using the Edinburgh Postnatal Depression Scale.

Venkatesh KK, Kaimal AJ, Castro VM, Perlis RH.

J Affect Disord. 2017 May;214:1-7. doi: 10.1016/j.jad.2017.01.042. Epub 2017 Feb 24.

PMID:
28260619
23.

T cell immunoregulation in active ocular toxoplasmosis.

Cordeiro CA, Vieira ELM, Castro VM, Dutra WO, Costa RA, Orefice JL, Campos WR, Orefice F, Young LH, Teixeira AL.

Immunol Lett. 2017 Apr;184:84-91. doi: 10.1016/j.imlet.2017.02.009. Epub 2017 Feb 16.

PMID:
28214536
24.

Validation of a risk stratification tool for fall-related injury in a state-wide cohort.

McCoy TH Jr, Castro VM, Cagan A, Roberson AM, Perlis RH.

BMJ Open. 2017 Feb 6;7(2):e012189. doi: 10.1136/bmjopen-2016-012189.

25.

Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis.

Cordeiro CA, Vieira EL, Rocha NP, Castro VM, Oréfice JL, Barichello T, Costa RA, Oréfice F, Young L, Teixeira AL.

Braz J Infect Dis. 2017 Mar - Apr;21(2):176-179. doi: 10.1016/j.bjid.2016.11.005. Epub 2016 Dec 5.

26.

Large-scale identification of patients with cerebral aneurysms using natural language processing.

Castro VM, Dligach D, Finan S, Yu S, Can A, Abd-El-Barr M, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Weiss ST, Du R.

Neurology. 2017 Jan 10;88(2):164-168. doi: 10.1212/WNL.0000000000003490. Epub 2016 Dec 7.

27.

Predicting early psychiatric readmission with natural language processing of narrative discharge summaries.

Rumshisky A, Ghassemi M, Naumann T, Szolovits P, Castro VM, McCoy TH, Perlis RH.

Transl Psychiatry. 2016 Oct 18;6(10):e921. doi: 10.1038/tp.2015.182.

28.

Improving Prediction of Suicide and Accidental Death After Discharge From General Hospitals With Natural Language Processing.

McCoy TH Jr, Castro VM, Roberson AM, Snapper LA, Perlis RH.

JAMA Psychiatry. 2016 Oct 1;73(10):1064-1071. doi: 10.1001/jamapsychiatry.2016.2172.

PMID:
27626235
29.

Predicting Suicidal Behavior From Longitudinal Electronic Health Records.

Barak-Corren Y, Castro VM, Javitt S, Hoffnagle AG, Dai Y, Perlis RH, Nock MK, Smoller JW, Reis BY.

Am J Psychiatry. 2017 Feb 1;174(2):154-162. doi: 10.1176/appi.ajp.2016.16010077. Epub 2016 Sep 9.

PMID:
27609239
30.

Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research.

Boutin NT, Mathieu K, Hoffnagle AG, Allen NL, Castro VM, Morash M, O'Rourke PP, Hohmann EL, Herring N, Bry L, Slaugenhaupt SA, Karlson EW, Weiss ST, Smoller JW.

J Pers Med. 2016 Jun 9;6(2). pii: E17. doi: 10.3390/jpm6020017.

31.

Prevalence and implications of cytochrome P450 substrates in Massachusetts hospital discharges.

McCoy TH, Castro VM, Cagan A, Roberson AM, Perlis RH.

Pharmacogenomics J. 2017 Jul;17(4):382-385. doi: 10.1038/tpj.2016.24. Epub 2016 May 10.

PMID:
27168099
32.

Association of Antenatal Depression Symptoms and Antidepressant Treatment With Preterm Birth.

Venkatesh KK, Riley L, Castro VM, Perlis RH, Kaimal AJ.

Obstet Gynecol. 2016 May;127(5):926-33. doi: 10.1097/AOG.0000000000001397.

PMID:
27054941
33.

The Biobank Portal for Partners Personalized Medicine: A Query Tool for Working with Consented Biobank Samples, Genotypes, and Phenotypes Using i2b2.

Gainer VS, Cagan A, Castro VM, Duey S, Ghosh B, Goodson AP, Goryachev S, Metta R, Wang TD, Wattanasin N, Murphy SN.

J Pers Med. 2016 Feb 26;6(1). pii: E11. doi: 10.3390/jpm6010011.

34.

Pre-birth cohort study of atopic dermatitis and severe bronchiolitis during infancy.

Balekian DS, Linnemann RW, Castro VM, Perlis R, Thadhani R, Camargo CA Jr.

Pediatr Allergy Immunol. 2016 Jun;27(4):413-8. doi: 10.1111/pai.12532. Epub 2016 Feb 26.

PMID:
26766307
35.

Absence of evidence for increase in risk for autism or attention-deficit hyperactivity disorder following antidepressant exposure during pregnancy: a replication study.

Castro VM, Kong SW, Clements CC, Brady R, Kaimal AJ, Doyle AE, Robinson EB, Churchill SE, Kohane IS, Perlis RH.

Transl Psychiatry. 2016 Jan 5;6:e708. doi: 10.1038/tp.2015.190.

36.

Antidepressant nonadherence in routine clinical settings determined from discarded blood samples.

Roberson AM, Castro VM, Cagan A, Perlis RH.

J Clin Psychiatry. 2016 Mar;77(3):359-62. doi: 10.4088/JCP.14m09612.

PMID:
26613178
37.

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.

Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA; Members of the International Cohort Collection for Bipolar Disorder (ICCBD), Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Landén M, Smoller JW, Perlis RH, Lee PH, Castro VM, Hoffnagle AG, Sklar P, Stahl EA, Purcell SM, Ruderfer DM, Charney AW, Roussos P, Michele Pato CP, Medeiros H, Sobel J, Craddock N, Jones I, Forty L, Florio AD, Green E, Jones L, Gordon-Smith K, Landen M, Hultman C, Jureus A, Bergen S, McCarroll S, Moran J, Smoller JW, Chambert K, Belliveau RA.

Mol Psychiatry. 2016 Sep;21(9):1290-7. doi: 10.1038/mp.2015.165. Epub 2015 Oct 27. Erratum in: Mol Psychiatry. 2017 Aug;22(8):1223.

38.

Sentiment Measured in Hospital Discharge Notes Is Associated with Readmission and Mortality Risk: An Electronic Health Record Study.

McCoy TH, Castro VM, Cagan A, Roberson AM, Kohane IS, Perlis RH.

PLoS One. 2015 Aug 24;10(8):e0136341. doi: 10.1371/journal.pone.0136341. eCollection 2015.

39.

Stratifying Risk for Renal Insufficiency Among Lithium-Treated Patients: An Electronic Health Record Study.

Castro VM, Roberson AM, McCoy TH, Wiste A, Cagan A, Smoller JW, Rosenbaum JF, Ostacher M, Perlis RH.

Neuropsychopharmacology. 2016 Mar;41(4):1138-43. doi: 10.1038/npp.2015.254. Epub 2015 Aug 21.

40.

A Systematic Evaluation of the QTc Interval and Antidepressants in Youth: An Electronic Health Record Study.

Uchida M, Spencer AE, Biederman J, Castro VM, Kenworthy T, Chan J, Rosales AM, Newton-Cheh C, Perlis RH.

J Dev Behav Pediatr. 2015 Jul-Aug;36(6):434-9. doi: 10.1097/DBP.0000000000000188.

PMID:
26154713
41.

Macular dystrophy associated with Kjellin's syndrome: a case report.

Castro VM, Meirelles A, Arcieri RS, Messias K, Messias A.

Arq Bras Oftalmol. 2015 Mar-Apr;78(2):120-2. doi: 10.5935/0004-2749.20150031.

42.

Validation of electronic health record phenotyping of bipolar disorder cases and controls.

Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW; International Cohort Collection for Bipolar Disorder Consortium.

Am J Psychiatry. 2015 Apr;172(4):363-72. doi: 10.1176/appi.ajp.2014.14030423. Epub 2014 Dec 12.

43.

A clinical perspective on the relevance of research domain criteria in electronic health records.

McCoy TH, Castro VM, Rosenfield HR, Cagan A, Kohane IS, Perlis RH.

Am J Psychiatry. 2015 Apr;172(4):316-20. doi: 10.1176/appi.ajp.2014.14091177.

PMID:
25827030
44.

Evaluation of matched control algorithms in EHR-based phenotyping studies: a case study of inflammatory bowel disease comorbidities.

Castro VM, Apperson WK, Gainer VS, Ananthakrishnan AN, Goodson AP, Wang TD, Herrick CD, Murphy SN.

J Biomed Inform. 2014 Dec;52:105-11. doi: 10.1016/j.jbi.2014.08.012. Epub 2014 Sep 6.

45.

Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.

Clements CC, Castro VM, Blumenthal SR, Rosenfield HR, Murphy SN, Fava M, Erb JL, Churchill SE, Kaimal AJ, Doyle AE, Robinson EB, Smoller JW, Kohane IS, Perlis RH.

Mol Psychiatry. 2015 Jun;20(6):727-34. doi: 10.1038/mp.2014.90. Epub 2014 Aug 26.

46.

An electronic health records study of long-term weight gain following antidepressant use.

Blumenthal SR, Castro VM, Clements CC, Rosenfield HR, Murphy SN, Fava M, Weilburg JB, Erb JL, Churchill SE, Kohane IS, Smoller JW, Perlis RH.

JAMA Psychiatry. 2014 Aug;71(8):889-96. doi: 10.1001/jamapsychiatry.2014.414.

PMID:
24898363
47.

Rare copy number variation in treatment-resistant major depressive disorder.

O'Dushlaine C, Ripke S, Ruderfer DM, Hamilton SP, Fava M, Iosifescu DV, Kohane IS, Churchill SE, Castro VM, Clements CC, Blumenthal SR, Murphy SN, Smoller JW, Perlis RH.

Biol Psychiatry. 2014 Oct 1;76(7):536-41. doi: 10.1016/j.biopsych.2013.10.028. Epub 2014 Jan 19.

48.

Stratification of risk for hospital admissions for injury related to fall: cohort study.

Castro VM, McCoy TH, Cagan A, Rosenfield HR, Murphy SN, Churchill SE, Kohane IS, Perlis RH.

BMJ. 2014 Oct 24;349:g5863. doi: 10.1136/bmj.g5863.

49.

Bilateral nongranulomatous anterior uveitis associated with chancre of the tongue: initial presentation of syphilis.

Freitas-Neto CA, Castro VM, Vasconcelos-Santos DV.

J Ophthalmic Inflamm Infect. 2013 Feb 11;3(1):33. doi: 10.1186/1869-5760-3-33.

50.

Axonal electrovisiogram or inverse photopic skin electroretinogram?

Messias K, Castro VM, Gekeler F, Messias A.

Arq Bras Oftalmol. 2012 Oct;75(5):370-1. No abstract available.

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