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Items: 1 to 50 of 348

1.

Engineering patient-specific cancer immunotherapies.

Scheetz L, Park KS, Li Q, Lowenstein PR, Castro MG, Schwendeman A, Moon JJ.

Nat Biomed Eng. 2019 Oct;3(10):768-782. doi: 10.1038/s41551-019-0436-x. Epub 2019 Aug 12. Review.

PMID:
31406259
2.

Distinct YFV Lineages Co-circulated in the Central-Western and Southeastern Brazilian Regions From 2015 to 2018.

Delatorre E, de Abreu FVS, Ribeiro IP, Gómez MM, Dos Santos AAC, Ferreira-de-Brito A, Neves MSAS, Bonelly I, de Miranda RM, Furtado ND, Raphael LMS, da Silva LFF, de Castro MG, Ramos DG, Romano APM, Kallás EG, Vicente ACP, Bello G, Lourenço-de-Oliveira R, Bonaldo MC.

Front Microbiol. 2019 May 24;10:1079. doi: 10.3389/fmicb.2019.01079. eCollection 2019.

3.

Is possible to rule out clinically significant prostate cancer using PI-RADS v2 for the assessment of prostate MRI?

Viana PCC, Horvat N, do Santos VR Júnior, Lima TC, Romão DDS, Cerri LMO, de Castro MG, Vargas HA, Miranda JA, Leite CDC, Cerri GG.

Int Braz J Urol. 2019 Jul-Aug;45(4):724-731. doi: 10.1590/S1677-5538.IBJU.2018.0382.

4.

Combination of surveillance tools reveals that Yellow Fever virus can remain in the same Atlantic Forest area at least for three transmission seasons.

Abreu FVS, Delatorre E, Dos Santos AAC, Ferreira-de-Brito A, de Castro MG, Ribeiro IP, Furtado ND, Vargas WP, Ribeiro MS, Meneguete P, Bonaldo MC, Bello G, Lourenço-de-Oliveira R.

Mem Inst Oswaldo Cruz. 2019;114:e190076. doi: 10.1590/0074-02760190076. Epub 2019 Apr 29.

5.

Effect of caveolin-1 on Stat3-ptyr705 levels in breast and lung carcinoma cells.

Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L.

Biochem Cell Biol. 2019 Oct;97(5):638-646. doi: 10.1139/bcb-2018-0367. Epub 2019 Apr 15.

6.

Haemagogus leucocelaenus and Haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in Brazil, 2016-2018.

Abreu FVS, Ribeiro IP, Ferreira-de-Brito A, Santos AACD, Miranda RM, Bonelly IS, Neves MSAS, Bersot MI, Santos TPD, Gomes MQ, Silva JLD, Romano APM, Carvalho RG, Said RFDC, Ribeiro MS, Laperrière RDC, Fonseca EOL, Falqueto A, Paupy C, Failloux AB, Moutailler S, Castro MG, Gómez MM, Motta MA, Bonaldo MC, Lourenço-de-Oliveira R.

Emerg Microbes Infect. 2019;8(1):218-231. doi: 10.1080/22221751.2019.1568180.

7.

Current technologies in body composition assessment: advantages and disadvantages.

Ceniccola GD, Castro MG, Piovacari SMF, Horie LM, Corrêa FG, Barrere APN, Toledo DO.

Nutrition. 2019 Jun;62:25-31. doi: 10.1016/j.nut.2018.11.028. Epub 2018 Dec 6. Review.

PMID:
30826596
8.

A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche.

Oliver CR, Altemus MA, Westerhof TM, Cheriyan H, Cheng X, Dziubinski M, Wu Z, Yates J, Morikawa A, Heth J, Castro MG, Leung BM, Takayama S, Merajver SD.

Lab Chip. 2019 Mar 27;19(7):1162-1173. doi: 10.1039/c8lc01387j.

PMID:
30810557
9.

Teach students, Empower patients, Act collaboratively and Meet health goals: an early interprofessional clinical experience in transformed care.

Castro MG, Dicks M, Fallin-Bennett K, Hustedde C, Sacks D, Hunter LJ, Elder W.

Adv Med Educ Pract. 2019 Feb 5;10:47-53. doi: 10.2147/AMEP.S175413. eCollection 2019.

10.

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaaq1427. doi: 10.1126/scitranslmed.aaq1427.

11.

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme.

Kadiyala P, Li D, Nuñez FM, Altshuler D, Doherty R, Kuai R, Yu M, Kamran N, Edwards M, Moon JJ, Lowenstein PR, Castro MG, Schwendeman A.

ACS Nano. 2019 Feb 26;13(2):1365-1384. doi: 10.1021/acsnano.8b06842. Epub 2019 Feb 11.

12.

Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures.

Núñez FJ, Mendez FM, Garcia-Fabiani MB, Pardo J, Edwards M, Lowenstein PR, Castro MG.

J Vis Exp. 2019 Jan 9;(143). doi: 10.3791/58931.

13.

Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy.

Guan X, Hasan MN, Begum G, Kohanbash G, Carney KE, Pigott VM, Persson AI, Castro MG, Jia W, Sun D.

Cell Death Dis. 2018 Sep 27;9(10):1010. doi: 10.1038/s41419-018-1062-3.

14.

Mutant ATRX: uncovering a new therapeutic target for glioma.

Haase S, Garcia-Fabiani MB, Carney S, Altshuler D, Núñez FJ, Méndez FM, Núñez F, Lowenstein PR, Castro MG.

Expert Opin Ther Targets. 2018 Jul;22(7):599-613. doi: 10.1080/14728222.2018.1487953. Epub 2018 Jun 20. Review.

15.

Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event.

Koschmann C, Farooqui Z, Kasaian K, Cao X, Zamler D, Stallard S, Venneti S, Hervey-Jumper S, Garton H, Muraszko K, Franchi L, Robertson PL, Leonard M, Opipari V, Castro MG, Lowenstein PR, Chinnaiyan A, Mody R.

NPJ Precis Oncol. 2017 Sep 14;1(1):32. doi: 10.1038/s41698-017-0033-y. eCollection 2017.

16.

Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab.

Yadav VN, Altshuler D, Kadiyala P, Zamler D, Comba A, Appelman H, Dunn P, Koschmann C, Castro MG, Löwenstein PR.

Neuro Oncol. 2018 Sep 3;20(10):1356-1367. doi: 10.1093/neuonc/noy055.

17.

A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.

Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, Kalathoor S, Vanover DA, Santangelo PJ, Ahmed R, Bryksin AV, Dahlman JE.

Nano Lett. 2018 Mar 14;18(3):2148-2157. doi: 10.1021/acs.nanolett.8b00432. Epub 2018 Mar 5.

18.

Genomic and structural features of the yellow fever virus from the 2016-2017 Brazilian outbreak.

Gómez MM, Abreu FVS, Santos AACD, Mello IS, Santos MP, Ribeiro IP, Ferreira-de-Brito A, Miranda RM, Castro MG, Ribeiro MS, Laterrière Junior RDC, Aguiar SF, Meira GLS, Antunes D, Torres PHM, Mir D, Vicente ACP, Guimarães ACR, Caffarena ER, Bello G, Lourenço-de-Oliveira R, Bonaldo MC.

J Gen Virol. 2018 Apr;99(4):536-548. doi: 10.1099/jgv.0.001033. Epub 2018 Feb 22.

PMID:
29469689
19.

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres.

Mendez FM, Núñez FJ, Zorrilla-Veloz RI, Lowenstein PR, Castro MG.

J Vis Exp. 2018 Jan 29;(131). doi: 10.3791/57016.

20.

Current state and future prospects of immunotherapy for glioma.

Kamran N, Alghamri MS, Nunez FJ, Shah D, Asad AS, Candolfi M, Altshuler D, Lowenstein PR, Castro MG.

Immunotherapy. 2018 Feb 1;10(4):317-339. doi: 10.2217/imt-2017-0122. Review.

21.

Melanoma induced immunosuppression is mediated by hematopoietic dysregulation.

Kamran N, Li Y, Sierra M, Alghamri MS, Kadiyala P, Appelman HD, Edwards M, Lowenstein PR, Castro MG.

Oncoimmunology. 2017 Dec 14;7(3):e1408750. doi: 10.1080/2162402X.2017.1408750. eCollection 2018. Erratum in: Oncoimmunology. 2018 Feb 1;7(4):e1431073.

22.

Zika virus can be venereally transmitted between Aedes aegypti mosquitoes.

Campos SS, Fernandes RS, Dos Santos AAC, de Miranda RM, Telleria EL, Ferreira-de-Brito A, de Castro MG, Failloux AB, Bonaldo MC, Lourenço-de-Oliveira R.

Parasit Vectors. 2017 Dec 15;10(1):605. doi: 10.1186/s13071-017-2543-4.

23.

In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate.

Castro MG, Campos LE, Rodriguez YI, Alvarez SE.

Methods Mol Biol. 2018;1697:117-131. doi: 10.1007/7651_2017_51.

PMID:
28755279
24.

Dengue serotype circulation in natural populations of Aedes aegypti.

Dos Santos TP, Cruz OG, da Silva KAB, de Castro MG, de Brito AF, Maspero RC, de Alcântra R, Dos Santos FB, Honorio NA, Lourenço-de-Oliveira R.

Acta Trop. 2017 Dec;176:140-143. doi: 10.1016/j.actatropica.2017.07.014. Epub 2017 Jul 23.

25.

Evolutionary basis of a new gene- and immune-therapeutic approach for the treatment of malignant brain tumors: from mice to clinical trials for glioma patients.

Lowenstein PR, Castro MG.

Clin Immunol. 2018 Apr;189:43-51. doi: 10.1016/j.clim.2017.07.006. Epub 2017 Jul 15. Review.

26.

Genome analysis of yellow fever virus of the ongoing outbreak in Brazil reveals polymorphisms.

Bonaldo MC, Gómez MM, Dos Santos AA, Abreu FVS, Ferreira-de-Brito A, Miranda RM, Castro MG, Lourenço-de-Oliveira R.

Mem Inst Oswaldo Cruz. 2017 Jun;112(6):447-451. doi: 10.1590/0074-02760170134.

27.

Dual activation of Toll-like receptors 7 and 9 impairs the efficacy of antitumor vaccines in murine models of metastatic breast cancer.

Moreno Ayala MA, Gottardo MF, Gori MS, Nicola Candia AJ, Caruso C, De Laurentiis A, Imsen M, Klein S, Bal de Kier Joffé E, Salamone G, Castro MG, Seilicovich A, Candolfi M.

J Cancer Res Clin Oncol. 2017 Sep;143(9):1713-1732. doi: 10.1007/s00432-017-2421-7. Epub 2017 Apr 21.

PMID:
28432455
28.

Single vs. combination immunotherapeutic strategies for glioma.

Chandran M, Candolfi M, Shah D, Mineharu Y, Yadav VN, Koschmann C, Asad AS, Lowenstein PR, Castro MG.

Expert Opin Biol Ther. 2017 May;17(5):543-554. doi: 10.1080/14712598.2017.1305353. Epub 2017 Mar 20. Review.

29.

PREVALENCE OF SMALL INTESTINE BACTERIAL OVERGROWTH IN PATIENTS WITH GASTROINTESTINAL SYMPTOMS.

Martins CP, Chaves CHA, Castro MGB, Gomes IC, Passos MDCF.

Arq Gastroenterol. 2017 Apr-Jun;54(2):91-95. doi: 10.1590/S0004-2803.201700000-06. Epub 2017 Feb 23.

30.

Biomarkers in pulmonary hypertension: An ongoing quest for better outcomes.

Castro MG.

Rev Port Cardiol. 2017 Feb;36(2):127-128. doi: 10.1016/j.repc.2016.12.005. Epub 2017 Jan 30. English, Portuguese. No abstract available.

31.

Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.

Kamran N, Kadiyala P, Saxena M, Candolfi M, Li Y, Moreno-Ayala MA, Raja N, Shah D, Lowenstein PR, Castro MG.

Mol Ther. 2017 Jan 4;25(1):232-248. doi: 10.1016/j.ymthe.2016.10.003. Epub 2017 Jan 4.

32.

Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer.

Koschmann C, Nunez FJ, Mendez F, Brosnan-Cashman JA, Meeker AK, Lowenstein PR, Castro MG.

Cancer Res. 2017 Jan 15;77(2):227-233. doi: 10.1158/0008-5472.CAN-16-2301. Epub 2017 Jan 6. Review.

33.

Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1.

Ashley SL, Pretto CD, Stier MT, Kadiyala P, Castro-Jorge L, Hsu TH, Doherty R, Carnahan KE, Castro MG, Lowenstein PR, Spindler KR.

J Virol. 2017 Feb 28;91(6). pii: e01412-16. doi: 10.1128/JVI.01412-16. Print 2017 Mar 15.

34.

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.

Yadav VN, Zamler D, Baker GJ, Kadiyala P, Erdreich-Epstein A, DeCarvalho AC, Mikkelsen T, Castro MG, Lowenstein PR.

Oncotarget. 2016 Dec 13;7(50):83701-83719. doi: 10.18632/oncotarget.13295.

35.

Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy.

Kamran N, Chandran M, Lowenstein PR, Castro MG.

Clin Immunol. 2018 Apr;189:34-42. doi: 10.1016/j.clim.2016.10.008. Epub 2016 Oct 21. Review.

36.

Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment.

Rodriguez YI, Campos LE, Castro MG, Aladhami A, Oskeritzian CA, Alvarez SE.

Front Oncol. 2016 Oct 17;6:218. eCollection 2016. Review.

37.

First detection of natural infection of Aedes aegypti with Zika virus in Brazil and throughout South America.

Ferreira-de-Brito A, Ribeiro IP, Miranda RM, Fernandes RS, Campos SS, Silva KA, Castro MG, Bonaldo MC, Brasil P, Lourenço-de-Oliveira R.

Mem Inst Oswaldo Cruz. 2016 Oct;111(10):655-658. doi: 10.1590/0074-02760160332. Epub 2016 Oct 3.

38.

Culex quinquefasciatus from Rio de Janeiro Is Not Competent to Transmit the Local Zika Virus.

Fernandes RS, Campos SS, Ferreira-de-Brito A, Miranda RM, Barbosa da Silva KA, Castro MG, Raphael LM, Brasil P, Failloux AB, Bonaldo MC, Lourenço-de-Oliveira R.

PLoS Negl Trop Dis. 2016 Sep 6;10(9):e0004993. doi: 10.1371/journal.pntd.0004993. eCollection 2016 Sep.

39.

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.

Koschmann C, Zamler D, MacKay A, Robinson D, Wu YM, Doherty R, Marini B, Tran D, Garton H, Muraszko K, Robertson P, Leonard M, Zhao L, Bixby D, Peterson L, Camelo-Piragua S, Jones C, Mody R, Lowenstein PR, Castro MG.

Oncotarget. 2016 Oct 4;7(40):65696-65706. doi: 10.18632/oncotarget.11602.

41.

Survival and Proliferation of Neural Progenitor-Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism.

Calinescu AA, Yadav VN, Carballo E, Kadiyala P, Tran D, Zamler DB, Doherty R, Srikanth M, Lowenstein PR, Castro MG.

Clin Cancer Res. 2017 Mar 1;23(5):1250-1262. doi: 10.1158/1078-0432.CCR-15-2888. Epub 2016 Aug 19.

42.

Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas.

Lowenstein PR, Castro MG.

Clin Cancer Res. 2016 Oct 1;22(19):4760-4762. Epub 2016 Aug 12.

43.

Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells.

Baker GJ, Chockley P, Zamler D, Castro MG, Lowenstein PR.

Oncoimmunology. 2016 Mar 16;5(6):e1163461. doi: 10.1080/2162402X.2016.1163461. eCollection 2016 Jun.

44.

The Bariatric Patient in the Intensive Care Unit: Pitfalls and Management.

Pompilio CE, Pelosi P, Castro MG.

Curr Atheroscler Rep. 2016 Sep;18(9):55. doi: 10.1007/s11883-016-0606-1. Review.

PMID:
27464648
45.

Recent advances and future of immunotherapy for glioblastoma.

Kamran N, Calinescu A, Candolfi M, Chandran M, Mineharu Y, Asad AS, Koschmann C, Nunez FJ, Lowenstein PR, Castro MG.

Expert Opin Biol Ther. 2016 Oct;16(10):1245-64. doi: 10.1080/14712598.2016.1212012. Epub 2016 Jul 27. Review.

46.

Isolation of Infective Zika Virus from Urine and Saliva of Patients in Brazil.

Bonaldo MC, Ribeiro IP, Lima NS, Dos Santos AA, Menezes LS, da Cruz SO, de Mello IS, Furtado ND, de Moura EE, Damasceno L, da Silva KA, de Castro MG, Gerber AL, de Almeida LG, Lourenço-de-Oliveira R, Vasconcelos AT, Brasil P.

PLoS Negl Trop Dis. 2016 Jun 24;10(6):e0004816. doi: 10.1371/journal.pntd.0004816. eCollection 2016 Jun.

47.

ATRX mutations and glioblastoma: Impaired DNA damage repair, alternative lengthening of telomeres, and genetic instability.

Koschmann C, Lowenstein PR, Castro MG.

Mol Cell Oncol. 2016 Apr 27;3(3):e1167158. doi: 10.1080/23723556.2016.1167158. eCollection 2016 May.

48.

The Long and Winding Road: From the High-Affinity Choline Uptake Site to Clinical Trials for Malignant Brain Tumors.

Lowenstein PR, Castro MG.

Adv Pharmacol. 2016;76:147-73. doi: 10.1016/bs.apha.2016.03.002. Epub 2016 Apr 23. Review.

49.

Microtubule targeting agents in glioma.

Calinescu AA, Castro MG.

Transl Cancer Res. 2016 Jun;5(Suppl 1):S54-S60. doi: 10.21037/tcr.2016.06.12. No abstract available.

50.

Fitness, insulin sensitivity, and frontal lobe integrity in adults with overweight and obesity.

Castro MG, Venutolo C, Yau PL, Convit A.

Obesity (Silver Spring). 2016 Jun;24(6):1283-9. doi: 10.1002/oby.21500. Epub 2016 Apr 28.

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