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Items: 1 to 50 of 94

1.

Myeloid HIF-1α regulates pulmonary inflammation during experimental Mycobacterium tuberculosis infection.

Resende M, Ferreira CM, Barbosa AM, Cardoso MS, Sousa J, Saraiva M, Castro AG, Appelberg R, Torrado E.

Immunology. 2019 Oct 13. doi: 10.1111/imm.13131. [Epub ahead of print]

PMID:
31606895
2.

TNF-Mediated Compensatory Immunity to Mycobacterium avium in the Absence of Macrophage Activation by IFN-γ.

Resende M, Cardoso MS, Fróis-Martins R, Borges M, Jordan MB, Castro AG, Appelberg R.

J Immunol. 2019 Nov 1;203(9):2451-2458. doi: 10.4049/jimmunol.1801594. Epub 2019 Sep 27.

PMID:
31562208
3.

Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection.

Fraga AG, Trigo G, Murthy RK, Akhtar S, Hebbur M, Pacheco AR, Dominguez J, Silva-Gomes R, Gonçalves CM, Oliveira H, Castro AG, Sharma U, Azeredo J, Pedrosa J.

PLoS Negl Trop Dis. 2019 Aug 19;13(8):e0007113. doi: 10.1371/journal.pntd.0007113. eCollection 2019 Aug.

4.

Predictors and outcomes of disseminated tuberculosis in an intermediate burden setting.

Meira L, Chaves C, Araújo D, Almeida L, Boaventura R, Ramos A, Carvalho T, Osório NS, Castro AG, Rodrigues F, Guimarães JT, Saraiva M, Bastos HN.

Pulmonology. 2019 Nov - Dec;25(6):320-327. doi: 10.1016/j.pulmoe.2018.11.001. Epub 2019 Feb 26.

5.

A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis.

Bhatt K, Machado H, Osório NS, Sousa J, Cardoso F, Magalhães C, Chen B, Chen M, Kim J, Singh A, Ferreira CM, Castro AG, Torrado E, Jacobs WR Jr, Bhatt A, Saraiva M.

mSphere. 2018 Oct 31;3(5). pii: e00352-18. doi: 10.1128/mSphere.00352-18.

6.

L-Threonine Supplementation During Colitis Onset Delays Disease Recovery.

Gaifem J, Gonçalves LG, Dinis-Oliveira RJ, Cunha C, Carvalho A, Torrado E, Rodrigues F, Saraiva M, Castro AG, Silvestre R.

Front Physiol. 2018 Sep 5;9:1247. doi: 10.3389/fphys.2018.01247. eCollection 2018.

7.

The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis.

Mesquita I, Ferreira C, Barbosa AM, Ferreira CM, Moreira D, Carvalho A, Cunha C, Rodrigues F, Dinis-Oliveira RJ, Estaquier J, Castro AG, Torrado E, Silvestre R.

Cytokine. 2018 Dec;112:16-20. doi: 10.1016/j.cyto.2018.07.001. Epub 2018 Jul 14.

PMID:
30017388
8.

Viability of Campylobacter spp. in frozen and chilled broiler carcasses according to real-time PCR with propidium monoazide pretreatment.

Castro AGSA, Dorneles EMS, Santos ELS, Alves TM, Silva GR, Figueiredo TC, Assis DCS, Lage AP, Cançado SV.

Poult Sci. 2018 May 1;97(5):1706-1711. doi: 10.3382/ps/pey020.

PMID:
29471351
9.

Development of a PCL-silica nanoparticles composite membrane for Guided Bone Regeneration.

Castro AGB, Diba M, Kersten M, Jansen JA, van den Beucken JJJP, Yang F.

Mater Sci Eng C Mater Biol Appl. 2018 Apr 1;85:154-161. doi: 10.1016/j.msec.2017.12.023. Epub 2017 Dec 21.

PMID:
29407143
10.

High systemic IL-6 is associated with worse prognosis in patients with non-small cell lung cancer.

Silva EM, Mariano VS, Pastrez PRA, Pinto MC, Castro AG, Syrjanen KJ, Longatto-Filho A.

PLoS One. 2017 Jul 17;12(7):e0181125. doi: 10.1371/journal.pone.0181125. eCollection 2017.

11.

Innate IFN-γ-Producing Cells Developing in the Absence of IL-2 Receptor Common γ-Chain.

Resende M, Cardoso MS, Ribeiro AR, Flórido M, Borges M, Castro AG, Alves NL, Cooper AM, Appelberg R.

J Immunol. 2017 Aug 15;199(4):1429-1439. doi: 10.4049/jimmunol.1601701. Epub 2017 Jul 7.

12.

Interferon-β regulates the production of IL-10 by toll-like receptor-activated microglia.

Lobo-Silva D, Carriche GM, Castro AG, Roque S, Saraiva M.

Glia. 2017 Sep;65(9):1439-1451. doi: 10.1002/glia.23172. Epub 2017 Jun 15.

PMID:
28617991
13.

IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.

Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Pinho Vaz C, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A Jr, Carvalho A.

J Allergy Clin Immunol. 2017 Sep;140(3):867-870.e9. doi: 10.1016/j.jaci.2017.02.034. Epub 2017 Apr 4. No abstract available.

PMID:
28389392
14.

Incorporation of PLLA micro-fillers for mechanical reinforcement of calcium-phosphate cement.

Castro AGB, Polini A, Azami Z, Leeuwenburgh SCG, Jansen JA, Yang F, van den Beucken JJJP.

J Mech Behav Biomed Mater. 2017 Jul;71:286-294. doi: 10.1016/j.jmbbm.2017.03.027. Epub 2017 Mar 28.

PMID:
28376362
15.

Balancing the immune response in the brain: IL-10 and its regulation.

Lobo-Silva D, Carriche GM, Castro AG, Roque S, Saraiva M.

J Neuroinflammation. 2016 Nov 24;13(1):297. Review.

16.

Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling.

Moreira-Teixeira L, Sousa J, McNab FW, Torrado E, Cardoso F, Machado H, Castro F, Cardoso V, Gaifem J, Wu X, Appelberg R, Castro AG, O'Garra A, Saraiva M.

J Immunol. 2016 Dec 15;197(12):4714-4726. Epub 2016 Nov 14.

17.

A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

Bastos HN, Osório NS, Castro AG, Ramos A, Carvalho T, Meira L, Araújo D, Almeida L, Boaventura R, Fragata P, Chaves C, Costa P, Portela M, Ferreira I, Magalhães SP, Rodrigues F, Sarmento-Castro R, Duarte R, Guimarães JT, Saraiva M.

PLoS One. 2016 Sep 16;11(9):e0162797. doi: 10.1371/journal.pone.0162797. eCollection 2016.

18.

Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment.

Silva JP, Gonçalves C, Costa C, Sousa J, Silva-Gomes R, Castro AG, Pedrosa J, Appelberg R, Gama FM.

J Control Release. 2016 Aug 10;235:112-124. doi: 10.1016/j.jconrel.2016.05.064. Epub 2016 Jun 1.

PMID:
27261333
19.

Two girls with a de novo Xq rearrangement of paternal origin: t(X;9)(q24;q12) or rea(X)dup q.

Vásquez-Velásquez AI, Rivera H, Castro AG, Jaloma-Cruz AR, Juárez CI, Lara-Navarro IJ, Córdova-Fletes C, Mendoza-Pérez P, García-Ortiz JE.

Taiwan J Obstet Gynecol. 2016 Apr;55(2):275-80. doi: 10.1016/j.tjog.2015.09.004.

20.

Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model.

Silva-Gomes R, Marcq E, Trigo G, Gonçalves CM, Longatto-Filho A, Castro AG, Pedrosa J, Fraga AG.

PLoS Negl Trop Dis. 2015 Dec 1;9(12):e0004265. doi: 10.1371/journal.pntd.0004265. eCollection 2015 Dec.

21.

IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages.

Cruz A, Ludovico P, Torrado E, Gama JB, Sousa J, Gaifem J, Appelberg R, Rodrigues F, Cooper AM, Pedrosa J, Saraiva M, Castro AG.

Front Immunol. 2015 Sep 30;6:498. doi: 10.3389/fimmu.2015.00498. eCollection 2015.

22.

Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study.

Martin-Loeches I, Povoa P, Rodríguez A, Curcio D, Suarez D, Mira JP, Cordero ML, Lepecq R, Girault C, Candeias C, Seguin P, Paulino C, Messika J, Castro AG, Valles J, Coelho L, Rabello L, Lisboa T, Collins D, Torres A, Salluh J, Nseir S; TAVeM study.

Lancet Respir Med. 2015 Nov;3(11):859-68. doi: 10.1016/S2213-2600(15)00326-4. Epub 2015 Oct 22.

PMID:
26472037
23.

Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.

Cardoso F, Castro F, Moreira-Teixeira L, Sousa J, Torrado E, Silvestre R, Castro AG, Saraiva M, Pais TF.

PLoS One. 2015 Jul 2;10(7):e0131904. doi: 10.1371/journal.pone.0131904. eCollection 2015.

24.

Clinical and videofluoroscopic diagnosis of dysphagia in chronic encephalopathy of childhood.

Araújo BC, Motta ME, de Castro AG, de Araújo CM.

Radiol Bras. 2014 Mar-Apr;47(2):84-8. doi: 10.1590/S0100-39842014000200009.

25.

Analysis of a local HIV-1 epidemic in portugal highlights established transmission of non-B and non-G subtypes.

Carvalho A, Costa P, Triunfante V, Branca F, Rodrigues F, Santos CL, Correia-Neves M, Saraiva M, Lecour H, Castro AG, Pedrosa J, Osório NS.

J Clin Microbiol. 2015 May;53(5):1506-14. doi: 10.1128/JCM.03611-14. Epub 2015 Feb 18.

26.

BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4⁺IL-17⁺TNF⁺IL-2⁺ T cells.

Cruz A, Torrado E, Carmona J, Fraga AG, Costa P, Rodrigues F, Appelberg R, Correia-Neves M, Cooper AM, Saraiva M, Pedrosa J, Castro AG.

Vaccine. 2015 Jan 1;33(1):85-91. doi: 10.1016/j.vaccine.2014.11.013. Epub 2014 Nov 20.

PMID:
25448107
27.

Synthesis and electrochemical study of a hybrid structure based on PDMS-TEOS and titania nanotubes for biomedical applications.

Castro AG, Bastos AC, Galstyan V, Faglia G, Sberveglieri G, Miranda Salvado IM.

Nanotechnology. 2014 Sep 12;25(36):365701.

PMID:
25141030
28.

Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages.

Teixeira-Coelho M, Guedes J, Ferreirinha P, Howes A, Pedrosa J, Rodrigues F, Lai WS, Blackshear PJ, O'Garra A, Castro AG, Saraiva M.

Eur J Immunol. 2014 Mar;44(3):856-66. doi: 10.1002/eji.201343734. Epub 2013 Dec 16.

29.

P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation.

Menino JF, Saraiva M, Gomes-Rezende J, Sturme M, Pedrosa J, Castro AG, Ludovico P, Goldman GH, Rodrigues F.

PLoS One. 2013 Sep 16;8(9):e74725. doi: 10.1371/journal.pone.0074725. eCollection 2013.

30.

TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.

Menino JF, Saraiva M, Gomes-Alves AG, Lobo-Silva D, Sturme M, Gomes-Rezende J, Saraiva AL, Goldman GH, Cunha C, Carvalho A, Romani L, Pedrosa J, Castro AG, Rodrigues F.

PLoS Negl Trop Dis. 2013 Jul 25;7(7):e2317. doi: 10.1371/journal.pntd.0002317. Print 2013.

31.

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response.

Carmona J, Cruz A, Moreira-Teixeira L, Sousa C, Sousa J, Osorio NS, Saraiva AL, Svenson S, Kallenius G, Pedrosa J, Rodrigues F, Castro AG, Saraiva M.

PLoS One. 2013 Jun 26;8(6):e67277. doi: 10.1371/journal.pone.0067277. Print 2013.

32.

Chondrogenic potential of two hASCs subpopulations loaded onto gellan gum hydrogel evaluated in a nude mice model.

Rada T, Carvalho PP, Santos TC, Castro AG, Reis RL, Gomes ME.

Curr Stem Cell Res Ther. 2013 Sep;8(5):357-64.

PMID:
23755728
33.

Phage therapy is effective against infection by Mycobacterium ulcerans in a murine footpad model.

Trigo G, Martins TG, Fraga AG, Longatto-Filho A, Castro AG, Azeredo J, Pedrosa J.

PLoS Negl Trop Dis. 2013 Apr 25;7(4):e2183. doi: 10.1371/journal.pntd.0002183. Print 2013.

34.

Evidence for diversifying selection in a set of Mycobacterium tuberculosis genes in response to antibiotic- and nonantibiotic-related pressure.

Osório NS, Rodrigues F, Gagneux S, Pedrosa J, Pinto-Carbó M, Castro AG, Young D, Comas I, Saraiva M.

Mol Biol Evol. 2013 Jun;30(6):1326-36. doi: 10.1093/molbev/mst038. Epub 2013 Feb 28.

PMID:
23449927
35.

Poor immune reconstitution in HIV-infected patients associates with high percentage of regulatory CD4+ T cells.

Horta A, Nobrega C, Amorim-Machado P, Coutinho-Teixeira V, Barreira-Silva P, Boavida S, Costa P, Sarmento-Castro R, Castro AG, Correia-Neves M.

PLoS One. 2013;8(2):e57336. doi: 10.1371/journal.pone.0057336. Epub 2013 Feb 20.

36.

Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection.

Martins TG, Trigo G, Fraga AG, Gama JB, Longatto-Filho A, Saraiva M, Silva MT, Castro AG, Pedrosa J.

PLoS Negl Trop Dis. 2012;6(11):e1925. doi: 10.1371/journal.pntd.0001925. Epub 2012 Nov 29.

37.

Vascular endothelial growth factor and fibroblast growth factor-2 incorporation in starch-based bone tissue-engineered constructs promote the in vivo expression of neovascularization mediators.

Santos TC, Morton TJ, Moritz M, Pfeifer S, Reise K, Marques AP, Castro AG, Reis RL, van Griensven M.

Tissue Eng Part A. 2013 Apr;19(7-8):834-48. doi: 10.1089/ten.TEA.2010.0741. Epub 2013 Feb 14.

PMID:
23173745
38.

Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation.

Mishra AK, Alves JE, Krumbach K, Nigou J, Castro AG, Geurtsen J, Eggeling L, Saraiva M, Besra GS.

J Biol Chem. 2012 Dec 28;287(53):44173-83. doi: 10.1074/jbc.M112.402396. Epub 2012 Nov 9.

39.

In vivo performance of chitosan/soy-based membranes as wound-dressing devices for acute skin wounds.

Santos TC, Höring B, Reise K, Marques AP, Silva SS, Oliveira JM, Mano JF, Castro AG, Reis RL, van Griensven M.

Tissue Eng Part A. 2013 Apr;19(7-8):860-9. doi: 10.1089/ten.TEA.2011.0651. Epub 2013 Feb 19.

40.

Cellular immunity confers transient protection in experimental Buruli ulcer following BCG or mycolactone-negative Mycobacterium ulcerans vaccination.

Fraga AG, Martins TG, Torrado E, Huygen K, Portaels F, Silva MT, Castro AG, Pedrosa J.

PLoS One. 2012;7(3):e33406. doi: 10.1371/journal.pone.0033406. Epub 2012 Mar 8.

41.

Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infection.

Martins TG, Gama JB, Fraga AG, Saraiva M, Silva MT, Castro AG, Pedrosa J.

PLoS One. 2012;7(2):e32740. doi: 10.1371/journal.pone.0032740. Epub 2012 Feb 29.

42.

The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation.

Carvalho A, Osório NS, Saraiva M, Cunha C, Almeida AJ, Teixeira-Coelho M, Ludovico P, Pedrosa J, Pitzurra L, Aversa F, Romani L, Castro AG, Rodrigues F.

PLoS One. 2011;6(11):e28256. doi: 10.1371/journal.pone.0028256. Epub 2011 Nov 23.

43.

The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma.

Carvalho A, Cunha C, Almeida AJ, Osório NS, Saraiva M, Teixeira-Coelho M, Pedreiro S, Torrado E, Domingues N, Gomes-Alves AG, Marques A, Lacerda JF, da Silva MG, Gomes M, Pinto AC, Torres F, Rendeiro P, Tavares P, Di Ianni M, Medeiros R, Heutink P, Bracci PM, Conde L, Ludovico P, Pedrosa J, Maciel P, Pitzurra L, Aversa F, Marques H, Paiva A, Skibola CF, Romani L, Castro AG, Rodrigues F.

Genes Immun. 2012 Feb;13(2):197-201. doi: 10.1038/gene.2011.59. Epub 2011 Aug 25.

44.

Comparative Study of Serological Tests for Mycoplasma synoviae Diagnosis in Commercial Poultry Breeders.

Luciano RL, Cardoso AL, Stoppa GF, Kanashiro AM, de Castro AG, Tessari EN.

Vet Med Int. 2011 Apr 3;2011:304349. doi: 10.4061/2011/304349.

45.

Osteogenic differentiation of two distinct subpopulations of human adipose-derived stem cells: an in vitro and in vivo study.

Rada T, Santos TC, Marques AP, Correlo VM, Frias AM, Castro AG, Neves NM, Gomes ME, Reis RL.

J Tissue Eng Regen Med. 2012 Jan;6(1):1-11. doi: 10.1002/term.388. Epub 2011 Feb 4.

PMID:
21294275
46.

TLR2 deficiency by compromising p19 (IL-23) expression limits Th 17 cell responses to Mycobacterium tuberculosis.

Teixeira-Coelho M, Cruz A, Carmona J, Sousa C, Ramos-Pereira D, Saraiva AL, Veldhoen M, Pedrosa J, Castro AG, Saraiva M.

Int Immunol. 2011 Feb;23(2):89-96. doi: 10.1093/intimm/dxq459. Epub 2010 Dec 14.

PMID:
21156751
47.

Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression.

Fraga AG, Cruz A, Martins TG, Torrado E, Saraiva M, Pereira DR, Meyers WM, Portaels F, Silva MT, Castro AG, Pedrosa J.

Infect Immun. 2011 Jan;79(1):421-30. doi: 10.1128/IAI.00820-10. Epub 2010 Oct 25.

48.

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis.

Cruz A, Fraga AG, Fountain JJ, Rangel-Moreno J, Torrado E, Saraiva M, Pereira DR, Randall TD, Pedrosa J, Cooper AM, Castro AG.

J Exp Med. 2010 Aug 2;207(8):1609-16. doi: 10.1084/jem.20100265. Epub 2010 Jul 12.

49.

In vivo short-term and long-term host reaction to starch-based scaffolds.

Santos TC, Marques AP, Höring B, Martins AR, Tuzlakoglu K, Castro AG, van Griensven M, Reis RL.

Acta Biomater. 2010 Nov;6(11):4314-26. doi: 10.1016/j.actbio.2010.06.020. Epub 2010 Jun 23.

PMID:
20601228
50.

Chitosan improves the biological performance of soy-based biomaterials.

Santos TC, Marques AP, Silva SS, Oliveira JM, Mano JF, Castro AG, van Griensven M, Reis RL.

Tissue Eng Part A. 2010 Sep;16(9):2883-90. doi: 10.1089/ten.TEA.2010.0114.

PMID:
20486796

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