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Items: 1 to 50 of 104

1.

Fecal IgA Levels and Gut Microbiota Composition Are Regulated by Invariant Natural Killer T Cells.

Aguiar CF, Castoldi A, Amano MT, Ignacio A, Terra FF, Cruz M, Felizardo RJF, Braga TT, Davanzo GG, Gambarini V, Antonio T, Antiorio ATFB, Hiyane MI, Morais da Fonseca D, Andrade-Oliveira V, Câmara NOS.

Inflamm Bowel Dis. 2019 Dec 10. pii: izz300. doi: 10.1093/ibd/izz300. [Epub ahead of print]

PMID:
31819985
2.

Metabolic adaptations of tissue-resident immune cells.

Caputa G, Castoldi A, Pearce EJ.

Nat Immunol. 2019 Jul;20(7):793-801. doi: 10.1038/s41590-019-0407-0. Epub 2019 Jun 18. Review.

PMID:
31213715
3.

Kinin B1 Receptor Acts in Adipose Tissue to Control Fat Distribution in a Cell-Nonautonomous Manner.

Sales VM, Gonçalves-Zillo T, Castoldi A, Burgos M, Branquinho J, Batista C, Oliveira V, Silva E, Castro CHM, Câmara N, Mori MA, Pesquero JB.

Diabetes. 2019 Aug;68(8):1614-1623. doi: 10.2337/db18-1150. Epub 2019 Jun 4.

PMID:
31167880
4.

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL.

Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23.

5.

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage.

Cameron AM, Castoldi A, Sanin DE, Flachsmann LJ, Field CS, Puleston DJ, Kyle RL, Patterson AE, Hässler F, Buescher JM, Kelly B, Pearce EL, Pearce EJ.

Nat Immunol. 2019 Apr;20(4):420-432. doi: 10.1038/s41590-019-0336-y. Epub 2019 Mar 11.

PMID:
30858618
6.

Butyrate Attenuates Lung Inflammation by Negatively Modulating Th9 Cells.

Vieira RS, Castoldi A, Basso PJ, Hiyane MI, Câmara NOS, Almeida RR.

Front Immunol. 2019 Jan 29;10:67. doi: 10.3389/fimmu.2019.00067. eCollection 2019.

7.

Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents.

Castoldi A, Empting M, De Rossi C, Mayr K, Dersch P, Hartmann R, Müller R, Gordon S, Lehr CM.

Pharm Res. 2018 Dec 5;36(1):22. doi: 10.1007/s11095-018-2521-3.

8.

Methionine supplementation stimulates mitochondrial respiration.

Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P.

Biochim Biophys Acta Mol Cell Res. 2018 Dec;1865(12):1901-1913. doi: 10.1016/j.bbamcr.2018.09.007. Epub 2018 Oct 2.

9.

Exercise rescues the immune response fine-tuned impaired by peroxisome proliferator-activated receptors γ deletion in macrophages.

Silveira LS, Batatinha HAP, Castoldi A, Câmara NOS, Festuccia WT, Souza CO, Rosa Neto JC, Lira FS.

J Cell Physiol. 2019 Apr;234(4):5241-5251. doi: 10.1002/jcp.27333. Epub 2018 Sep 21.

PMID:
30238979
10.

The lack of PI3Kγ favors M1 macrophage polarization and does not prevent kidney diseases progression.

Amano MT, Castoldi A, Andrade-Oliveira V, Latancia MT, Terra FF, Correa-Costa M, Breda CNS, Felizardo RJF, Pereira WO, da Silva MB, Miyagi MYS, Aguiar CF, Hiyane MI, Silva JS, Moura IC, Camara NOS.

Int Immunopharmacol. 2018 Nov;64:151-161. doi: 10.1016/j.intimp.2018.08.020. Epub 2018 Aug 31.

PMID:
30176533
11.

The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages.

de Albuquerque JAT, Banerjee PP, Castoldi A, Ma R, Zurro NB, Ynoue LH, Arslanian C, Barbosa-Carvalho MUW, Correia-Deur JEM, Weiler FG, Dias-da-Silva MR, Lazaretti-Castro M, Pedroza LA, Câmara NOS, Mace E, Orange JS, Condino-Neto A.

Front Immunol. 2018 Mar 21;9:567. doi: 10.3389/fimmu.2018.00567. eCollection 2018.

12.

TLR2 and TLR4 play opposite role in autophagy associated with cisplatin-induced acute kidney injury.

Andrade-Silva M, Cenedeze MA, Perandini LA, Felizardo RJF, Watanabe IKM, Agudelo JSH, Castoldi A, Gonçalves GM, Origassa CST, Semedo P, Hiyane MI, Foresto-Neto O, Malheiros DMAC, Reis MA, Fujihara CK, Zatz R, Pacheco-Silva A, Câmara NOS, de Almeida DC.

Clin Sci (Lond). 2018 Aug 22;132(16):1725-1739. doi: 10.1042/CS20170262. Print 2018 Aug 31.

PMID:
29500224
13.

Mesenchymal stromal cells modulate gut inflammation in experimental colitis.

de Aguiar CF, Castoldi A, Andrade-Oliveira V, Ignacio A, da Cunha FF, Felizardo RJF, Bassi ÊJ, Câmara NOS, de Almeida DC.

Inflammopharmacology. 2018 Feb;26(1):251-260. doi: 10.1007/s10787-017-0404-6. Epub 2017 Oct 23.

PMID:
29063489
14.

Mesenchymal Stromal Cell-Derived Microvesicles Regulate an Internal Pro-Inflammatory Program in Activated Macrophages.

Henao Agudelo JS, Braga TT, Amano MT, Cenedeze MA, Cavinato RA, Peixoto-Santos AR, Muscará MN, Teixeira SA, Cruz MC, Castoldi A, Sinigaglia-Coimbra R, Pacheco-Silva A, de Almeida DC, Camara NOS.

Front Immunol. 2017 Jul 31;8:881. doi: 10.3389/fimmu.2017.00881. eCollection 2017.

15.

Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.

Chimin P, Andrade ML, Belchior T, Paschoal VA, Magdalon J, Yamashita AS, Castro É, Castoldi A, Chaves-Filho AB, Yoshinaga MY, Miyamoto S, Câmara NO, Festuccia WT.

J Lipid Res. 2017 Sep;58(9):1797-1807. doi: 10.1194/jlr.M074518. Epub 2017 Jul 5.

16.

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.

Castoldi A, Andrade-Oliveira V, Aguiar CF, Amano MT, Lee J, Miyagi MT, Latância MT, Braga TT, da Silva MB, Ignácio A, Carola Correia Lima JD, Loures FV, Albuquerque JAT, Macêdo MB, Almeida RR, Gaiarsa JW, Luévano-Martínez LA, Belchior T, Hiyane MI, Brown GD, Mori MA, Hoffmann C, Seelaender M, Festuccia WT, Moraes-Vieira PM, Câmara NOS.

Cell Rep. 2017 Jun 13;19(11):2272-2288. doi: 10.1016/j.celrep.2017.05.059.

17.

Genotoxicity testing approaches for the safety assessment of substances used in food contact materials prior to their authorization in the European Union.

Bolognesi C, Castoldi AF, Crebelli R, Barthélémy E, Maurici D, Wölfle D, Volk K, Castle L.

Environ Mol Mutagen. 2017 Jun;58(5):361-374. doi: 10.1002/em.22094. Epub 2017 May 28. Review.

PMID:
28556235
18.

Soluble Uric Acid Activates the NLRP3 Inflammasome.

Braga TT, Forni MF, Correa-Costa M, Ramos RN, Barbuto JA, Branco P, Castoldi A, Hiyane MI, Davanso MR, Latz E, Franklin BS, Kowaltowski AJ, Camara NO.

Sci Rep. 2017 Jan 13;7:39884. doi: 10.1038/srep39884.

19.

Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections.

Castoldi A, Herr C, Niederstraßer J, Labouta HI, Melero A, Gordon S, Schneider-Daum N, Bals R, Lehr CM.

Eur J Pharm Biopharm. 2017 Sep;118:62-67. doi: 10.1016/j.ejpb.2016.11.026. Epub 2016 Nov 22.

PMID:
27888144
20.

The microbiota and chronic kidney diseases: a double-edged sword.

Felizardo RJ, Castoldi A, Andrade-Oliveira V, Câmara NO.

Clin Transl Immunology. 2016 Jun 10;5(6):e86. eCollection 2016 Jun. Review.

21.

Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses.

Lee J, Moraes-Vieira PM, Castoldi A, Aryal P, Yee EU, Vickers C, Parnas O, Donaldson CJ, Saghatelian A, Kahn BB.

J Biol Chem. 2016 Oct 14;291(42):22207-22217. Epub 2016 Aug 29.

22.

Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset.

Costa FR, Françozo MC, de Oliveira GG, Ignacio A, Castoldi A, Zamboni DS, Ramos SG, Câmara NO, de Zoete MR, Palm NW, Flavell RA, Silva JS, Carlos D.

J Exp Med. 2016 Jun 27;213(7):1223-39. doi: 10.1084/jem.20150744. Epub 2016 Jun 20.

23.

CETP Lowers TLR4 Expression Which Attenuates the Inflammatory Response Induced by LPS and Polymicrobial Sepsis.

Venancio TM, Machado RM, Castoldi A, Amano MT, Nunes VS, Quintao EC, Camara NO, Soriano FG, Cazita PM.

Mediators Inflamm. 2016;2016:1784014. doi: 10.1155/2016/1784014. Epub 2016 May 12.

24.

Retraction: Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice.

Caricilli AM, Picardi PK, de Abreu LL, Ueno M, Prada PO, Ropelle ER, Hirabara SM, Castoldi Â, Vieira P, Camara NO, Curi R, Carvalheira JB, Saad MJ.

PLoS Biol. 2016 May 23;14(5):e1002479. doi: 10.1371/journal.pbio.1002479. eCollection 2016 May. No abstract available.

25.

Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance.

Moraes-Vieira PM, Castoldi A, Aryal P, Wellenstein K, Peroni OD, Kahn BB.

Diabetes. 2016 May;65(5):1317-27. doi: 10.2337/db15-1696. Epub 2016 Mar 2.

26.

The Macrophage Switch in Obesity Development.

Castoldi A, Naffah de Souza C, Câmara NO, Moraes-Vieira PM.

Front Immunol. 2016 Jan 5;6:637. doi: 10.3389/fimmu.2015.00637. eCollection 2015. Review.

27.

A statement on the developmental immunotoxicity of bisphenol A (BPA): answer to the question from the Dutch Ministry of Health, Welfare and Sport.

Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Silano V, Bolognesi C, Castle L, Cravedi JP, Engel KH, Fowler P, Franz R, Grob K, Gürtler R, Kärenlampi S, Mennes W, Milana MR, Penninks A, Smith A, de Fátima Tavares Poças M, Tlustos C, Wölfle D, Zorn H, Zugravu CA, Anderson S, Germolec D, Pieters R, Castoldi AF, Husøy T.

EFSA J. 2016;14(10):e04580. doi: 10.2903/j.efsa.2016.4580. Epub 2016 Oct 13.

28.

Snf1 Phosphorylates Adenylate Cyclase and Negatively Regulates Protein Kinase A-dependent Transcription in Saccharomyces cerevisiae.

Nicastro R, Tripodi F, Gaggini M, Castoldi A, Reghellin V, Nonnis S, Tedeschi G, Coccetti P.

J Biol Chem. 2015 Oct 9;290(41):24715-26. doi: 10.1074/jbc.M115.658005. Epub 2015 Aug 26.

29.

They Must Hold Tight: Junction Proteins, Microbiota And Immunity In Intestinal Mucosa.

Castoldi A, Favero de Aguiar C, Moraes-Vieira PM, Olsen Saraiva Câmara N.

Curr Protein Pept Sci. 2015;16(7):655-71. Review.

PMID:
26122786
30.

Administration of α-Galactosylceramide Improves Adenine-Induced Renal Injury.

Aguiar CF, Naffah-de-Souza C, Castoldi A, Corrêa-Costa M, Braga TT, Naka ÉL, Amano MT, Abate DT, Hiyane MI, Cenedeze MA, Pacheco e Silva Filho A, Câmara NO.

Mol Med. 2015 Jun 18;21:553-62. doi: 10.2119/molmed.2014.00090.

31.

Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion.

Andrade-Oliveira V, Amano MT, Correa-Costa M, Castoldi A, Felizardo RJ, de Almeida DC, Bassi EJ, Moraes-Vieira PM, Hiyane MI, Rodas AC, Peron JP, Aguiar CF, Reis MA, Ribeiro WR, Valduga CJ, Curi R, Vinolo MA, Ferreira CM, Câmara NO.

J Am Soc Nephrol. 2015 Aug;26(8):1877-88. doi: 10.1681/ASN.2014030288. Epub 2015 Jan 14.

32.

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.

Zemany L, Bhanot S, Peroni OD, Murray SF, Moraes-Vieira PM, Castoldi A, Manchem P, Guo S, Monia BP, Kahn BB.

Diabetes. 2015 May;64(5):1603-14. doi: 10.2337/db14-0970. Epub 2014 Dec 18.

33.

Long-term aerobic exercise protects against cisplatin-induced nephrotoxicity by modulating the expression of IL-6 and HO-1.

Miyagi MY, Seelaender M, Castoldi A, de Almeida DC, Bacurau AV, Andrade-Oliveira V, Enjiu LM, Pisciottano M, Hayashida CY, Hiyane MI, Brum PC, Camara NO, Amano MT.

PLoS One. 2014 Oct 1;9(10):e108543. doi: 10.1371/journal.pone.0108543. eCollection 2014.

34.

A 3D in vitro cancer model as a platform for nanoparticle uptake and imaging investigations.

Ricketts KP, Cheema U, Nyga A, Castoldi A, Guazzoni C, Magdeldin T, Emberton M, Gibson AP, Royle GJ, Loizidou M.

Small. 2014 Oct 15;10(19):3954-61. doi: 10.1002/smll.201400194. Epub 2014 Jul 2.

35.

Intestinal barrier: A gentlemen's agreement between microbiota and immunity.

Caricilli AM, Castoldi A, Câmara NO.

World J Gastrointest Pathophysiol. 2014 Feb 15;5(1):18-32. doi: 10.4291/wjgp.v5.i1.18. Review.

36.

Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis.

Correa-Costa M, Andrade-Oliveira V, Braga TT, Castoldi A, Aguiar CF, Origassa CS, Rodas AC, Hiyane MI, Malheiros DM, Rios FJ, Jancar S, Câmara NO.

Lab Invest. 2014 Apr;94(4):455-66. doi: 10.1038/labinvest.2013.155. Epub 2014 Feb 3.

37.

Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration.

Estrela GR, Wasinski F, Almeida DC, Amano MT, Castoldi A, Dias CC, Malheiros DM, Almeida SS, Paredes-Gamero EJ, Pesquero JB, Barros CC, Câmara NO, Araújo RC.

J Mol Med (Berl). 2014 Apr;92(4):399-409. doi: 10.1007/s00109-013-1116-z. Epub 2013 Dec 20.

PMID:
24357263
38.

An x-ray fluorescence imaging system for gold nanoparticle detection.

Ricketts K, Guazzoni C, Castoldi A, Gibson AP, Royle GJ.

Phys Med Biol. 2013 Nov 7;58(21):7841-55. doi: 10.1088/0031-9155/58/21/7841. Epub 2013 Oct 21.

PMID:
24145214
39.

Low-level laser therapy decreases renal interstitial fibrosis.

Oliveira FA, Moraes AC, Paiva AP, Schinzel V, Correa-Costa M, Semedo P, Castoldi A, Cenedeze MA, Oliveira RS, Bastos MG, Câmara NO, Sanders-Pinheiro H.

Photomed Laser Surg. 2012 Dec;30(12):705-13. doi: 10.1089/pho.2012.3272. Epub 2012 Nov 7.

40.

Leptin deficiency modulates allograft survival by favoring a Th2 and a regulatory immune profile. [corrected].

Moraes-Vieira PM, Bassi EJ, Larocca RA, Castoldi A, Burghos M, Lepique AP, Quintana FJ, Araujo RC, Basso AS, Strom TB, Câmara NO.

Am J Transplant. 2013 Jan;13(1):36-44. doi: 10.1111/j.1600-6143.2012.04283.x. Epub 2012 Sep 27. Erratum in: Am J Transplant. 2013 Aug;13(8):2231.

41.

Oxidative stress and modification of renal vascular permeability are associated with acute kidney injury during P. berghei ANKA infection.

Elias RM, Correa-Costa M, Barreto CR, Silva RC, Hayashida CY, Castoldi A, Gonçalves GM, Braga TT, Barboza R, Rios FJ, Keller AC, Cenedeze MA, Hyane MI, D'Império-Lima MR, Figueiredo-Neto AM, Reis MA, Marinho CR, Pacheco-Silva A, Câmara NO.

PLoS One. 2012;7(8):e44004. doi: 10.1371/journal.pone.0044004. Epub 2012 Aug 31.

42.

A quantitative x-ray detection system for gold nanoparticle tumour biomarkers.

Ricketts K, Castoldi A, Guazzoni C, Ozkan C, Christodoulou C, Gibson AP, Royle GJ.

Phys Med Biol. 2012 Sep 7;57(17):5543-55. doi: 10.1088/0031-9155/57/17/5543. Epub 2012 Aug 8.

PMID:
22871575
43.

MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages.

Braga TT, Correa-Costa M, Guise YF, Castoldi A, de Oliveira CD, Hyane MI, Cenedeze MA, Teixeira SA, Muscara MN, Perez KR, Cuccovia IM, Pacheco-Silva A, Gonçalves GM, Camara NO.

Mol Med. 2012 Oct 24;18:1231-9. doi: 10.2119/molmed.2012.00131.

44.

TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis.

Castoldi A, Braga TT, Correa-Costa M, Aguiar CF, Bassi ÊJ, Correa-Silva R, Elias RM, Salvador F, Moraes-Vieira PM, Cenedeze MA, Reis MA, Hiyane MI, Pacheco-Silva Á, Gonçalves GM, Saraiva Câmara NO.

PLoS One. 2012;7(5):e37584. doi: 10.1371/journal.pone.0037584. Epub 2012 May 24.

45.

Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice.

Caricilli AM, Picardi PK, de Abreu LL, Ueno M, Prada PO, Ropelle ER, Hirabara SM, Castoldi Â, Vieira P, Camara NO, Curi R, Carvalheira JB, Saad MJ.

PLoS Biol. 2011 Dec;9(12):e1001212. doi: 10.1371/journal.pbio.1001212. Epub 2011 Dec 6. Retraction in: Caricilli AM, Picardi PK, de Abreu LL, Ueno M, Prada PO, Ropelle ER, Hirabara SM, Castoldi Â, Vieira P, Camara NO, Curi R, Carvalheira JB, Saad MJ. PLoS Biol. 2016 May;14(5):e1002479.

46.

Biosensors and molecular imaging.

Sampietro M, Bottani CE, Carminati M, Casari C, Castoldi A, Ferrari G, Fusi M, Guazzoni C, Rottigni A, Vergani M.

IEEE Pulse. 2011 May-Jun;2(3):35-40. doi: 10.1109/MPUL.2011.941521. Review.

PMID:
21642031
47.

Human risk assessment of heavy metals: principles and applications.

Dorne JL, Kass GE, Bordajandi LR, Amzal B, Bertelsen U, Castoldi AF, Heppner C, Eskola M, Fabiansson S, Ferrari P, Scaravelli E, Dogliotti E, Fuerst P, Boobis AR, Verger P.

Met Ions Life Sci. 2011;8:27-60.

PMID:
21473375
48.

Developmental exposure to methylmercury and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) affects cerebral dopamine D1-like and D2-like receptors of weanling and pubertal rats.

Coccini T, Roda E, Castoldi AF, Poli D, Goldoni M, Vettori MV, Mutti A, Manzo L.

Arch Toxicol. 2011 Oct;85(10):1281-94. doi: 10.1007/s00204-011-0660-y. Epub 2011 Feb 18.

PMID:
21331603
49.

New roles for innate immune response in acute and chronic kidney injuries.

Gonçalves GM, Castoldi A, Braga TT, Câmara NO.

Scand J Immunol. 2011 May;73(5):428-35. doi: 10.1111/j.1365-3083.2011.02523.x. Review.

50.

Comparative in vitro and ex-vivo myelotoxicity of aflatoxins B1 and M1 on haematopoietic progenitors (BFU-E, CFU-E, and CFU-GM): species-related susceptibility.

Roda E, Coccini T, Acerbi D, Castoldi AF, Manzo L.

Toxicol In Vitro. 2010 Feb;24(1):217-23. doi: 10.1016/j.tiv.2009.09.005. Epub 2009 Sep 9.

PMID:
19747537

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