Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 45

1.

Hydrocyclones as cell retention device for CHO perfusion processes in single-use bioreactors.

Bettinardi IW, Castan A, Medronho RA, Castilho LR.

Biotechnol Bioeng. 2020 Mar 17. doi: 10.1002/bit.27335. [Epub ahead of print]

PMID:
32181883
2.

Perfusion process combining low temperature and valeric acid for enhanced recombinant factor VIII production.

Coronel J, Heinrich C, Klausing S, Noll T, Figueredo-Cardero A, Castilho LR.

Biotechnol Prog. 2020 Jan;36(1):e2915. doi: 10.1002/btpr.2915. Epub 2019 Oct 22.

PMID:
31587517
3.

Purification of flavivirus VLPs by a two-step chomatographic process.

Lima TM, Souza MO, Castilho LR.

Vaccine. 2019 Nov 8;37(47):7061-7069. doi: 10.1016/j.vaccine.2019.05.066. Epub 2019 Jun 11.

4.

Zika virus-like particles (VLPs): Stable cell lines and continuous perfusion processes as a new potential vaccine manufacturing platform.

Alvim RGF, Itabaiana I Jr, Castilho LR.

Vaccine. 2019 Nov 8;37(47):6970-6977. doi: 10.1016/j.vaccine.2019.05.064. Epub 2019 Jun 1.

5.

Purification of yellow fever virus produced in Vero cells for inactivated vaccine manufacture.

Pato TP, Souza MCO, Mattos DA, Caride E, Ferreira DF, Gaspar LP, Freire MS, Castilho LR.

Vaccine. 2019 May 27;37(24):3214-3220. doi: 10.1016/j.vaccine.2019.04.077. Epub 2019 Apr 30.

PMID:
31047674
6.

Novel combination of a biosurfactant with entomopathogenic fungi enhances efficacy against Bemisia whitefly.

do Nascimento Silva J, Mascarin GM, de Paula Vieira de Castro R, Castilho LR, Freire DM.

Pest Manag Sci. 2019 Nov;75(11):2882-2891. doi: 10.1002/ps.5458. Epub 2019 Jun 4.

PMID:
31038255
7.

Intermediate purification of CHO-derived recombinant human Factor IX using hydrophobic interaction membrane-based chromatography and its comparison to a sulfated resin.

Ribeiro DA, Passos DF, Ferraz HC, Castilho LR.

Electrophoresis. 2017 Nov;38(22-23):2900-2908. doi: 10.1002/elps.201700226. Epub 2017 Sep 26.

PMID:
28869668
8.

Development of a 3-step straight-through purification strategy combining membrane adsorbers and resins.

Hughson MD, Cruz TA, Carvalho RJ, Castilho LR.

Biotechnol Prog. 2017 Jul;33(4):931-940. doi: 10.1002/btpr.2501. Epub 2017 Jun 19.

PMID:
28556541
9.

Investigations into, and development of, a lyophilized and formulated recombinant human factor IX produced from CHO cells.

Almeida AG, Pinto RCV, Smales CM, Castilho LR.

Biotechnol Lett. 2017 Aug;39(8):1109-1120. doi: 10.1007/s10529-017-2353-y. Epub 2017 May 8.

PMID:
28484912
10.

Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells.

Nikolay A, Castilho LR, Reichl U, Genzel Y.

Vaccine. 2018 May 24;36(22):3140-3145. doi: 10.1016/j.vaccine.2017.03.018. Epub 2017 Mar 23.

11.

Rapid development of a DNA vaccine for Zika virus.

Dowd KA, Ko SY, Morabito KM, Yang ES, Pelc RS, DeMaso CR, Castilho LR, Abbink P, Boyd M, Nityanandam R, Gordon DN, Gallagher JR, Chen X, Todd JP, Tsybovsky Y, Harris A, Huang YS, Higgs S, Vanlandingham DL, Andersen H, Lewis MG, De La Barrera R, Eckels KH, Jarman RG, Nason MC, Barouch DH, Roederer M, Kong WP, Mascola JR, Pierson TC, Graham BS.

Science. 2016 Oct 14;354(6309):237-240. Epub 2016 Sep 22.

12.

Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells.

Lages YM, Nascimento JM, Lemos GA, Galina A, Castilho LR, Rehen SK.

PeerJ. 2015 Dec 10;3:e1486. doi: 10.7717/peerj.1486. eCollection 2015.

13.

Immediate tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracycline.

Melo ME, Silva CA, de Souza Gomes WD, da Silva VF, Brandini DA, Poi WR, Castilho LR, Sonoda CK, Panzarini SR.

Clin Oral Investig. 2016 Apr;20(3):523-32. doi: 10.1007/s00784-015-1534-0. Epub 2015 Jul 24.

PMID:
26205067
14.

Increasing Vero viable cell densities for yellow fever virus production in stirred-tank bioreactors using serum-free medium.

Mattos DA, Silva MV, Gaspar LP, Castilho LR.

Vaccine. 2015 Aug 20;33(35):4288-91. doi: 10.1016/j.vaccine.2015.04.050. Epub 2015 Apr 27.

PMID:
25930117
15.

Multivariate optimization and supplementation strategies for the simultaneous production of amylases, cellulases, xylanases, and proteases by Aspergillus awamori under solid-state fermentation conditions.

de Castro AM, Castilho LR, Freire DM.

Appl Biochem Biotechnol. 2015 Feb;175(3):1588-602. doi: 10.1007/s12010-014-1368-2. Epub 2014 Nov 21.

PMID:
25413792
16.

Rotating cylindrical filters used in perfusion cultures: CFD simulations and experiments.

Figueredo-Cardero A, Martínez E, Chico E, Castilho LR, Medronho RA.

Biotechnol Prog. 2014 Sep-Oct;30(5):1093-102. doi: 10.1002/btpr.1945. Epub 2014 Jul 25.

PMID:
25059206
17.

Development of a membrane adsorber based capture step for the purification of yellow fever virus.

Pato TP, Souza MC, Silva AN, Pereira RC, Silva MV, Caride E, Gaspar LP, Freire MS, Castilho LR.

Vaccine. 2014 May 19;32(24):2789-93. doi: 10.1016/j.vaccine.2014.02.036. Epub 2014 Mar 11.

PMID:
24631080
18.

Anion-exchange purification of recombinant factor IX from cell culture supernatant using different chromatography supports.

Ribeiro DA, Passos DF, Ferraz HC, Castilho LR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Nov 1;938:111-8. doi: 10.1016/j.jchromb.2013.09.002. Epub 2013 Sep 7.

PMID:
24076525
19.

Prolonged acceptance of skin grafts induced by B cells places regulatory T cells on the histopathology scene.

Langier S, Galvani RG, Alves AP, Fidelis R, Nunes PH, Silva MH, Castilho LR, Monteiro JP, Bonomo A.

Braz J Med Biol Res. 2012 Oct;45(10):942-7. Epub 2012 May 31.

20.

Evaluation of the anti-resorptive ability of an experimental acetazolamide paste for the treatment of late replanted teeth: a study in rats.

Mori GG, Poi WR, Castilho LR.

Dent Traumatol. 2013 Feb;29(1):34-40. doi: 10.1111/j.1600-9657.2012.01131.x. Epub 2012 Mar 20.

PMID:
22429279
21.

Effect of zoledronic acid used in the root surface treatment of late replanted teeth: a study in rats.

Mori GG, Janjacomo DM, Nunes DC, Castilho LR.

Braz Dent J. 2010;21(5):452-7.

22.

Virus-like particles in vaccine development.

Roldão A, Mellado MC, Castilho LR, Carrondo MJ, Alves PM.

Expert Rev Vaccines. 2010 Oct;9(10):1149-76. doi: 10.1586/erv.10.115. Review.

PMID:
20923267
23.

Propolis as storage media for avulsed teeth: microscopic and morphometric analysis in rats.

Mori GG, Nunes DC, Castilho LR, de Moraes IG, Poi WR.

Dent Traumatol. 2010 Feb;26(1):80-5. doi: 10.1111/j.1600-9657.2009.00856.x.

PMID:
20089064
24.

Maintenance of pluripotency in mouse embryonic stem cells cultivated in stirred microcarrier cultures.

Marinho PA, Fernandes AM, Cruz JC, Rehen SK, Castilho LR.

Biotechnol Prog. 2010 Mar-Apr;26(2):548-55. doi: 10.1002/btpr.328.

PMID:
20014096
25.

CFD simulation of an internal spin-filter: evidence of lateral migration and exchange flow through the mesh.

Figueredo-Cardero A, Chico E, Castilho LR, Medronho RA.

Cytotechnology. 2009 Nov;61(1-2):55-64. doi: 10.1007/s10616-009-9242-8. Epub 2009 Dec 10.

26.

Evaluating the knowledge of sports participants regarding dental emergency procedures.

Mori GG, de Mendonça Janjácomo DM, Castilho LR, Poi WR.

Dent Traumatol. 2009 Jun;25(3):305-8. doi: 10.1111/j.1600-9657.2009.00786.x.

PMID:
19583579
27.

Production of polyhydroxyalkanoates (PHAs) from waste materials and by-products by submerged and solid-state fermentation.

Castilho LR, Mitchell DA, Freire DM.

Bioresour Technol. 2009 Dec;100(23):5996-6009. doi: 10.1016/j.biortech.2009.03.088. Epub 2009 Jul 5.

PMID:
19581084
28.

Production of an acidic and thermostable lipase of the mesophilic fungus Penicillium simplicissimum by solid-state fermentation.

Gutarra ML, Godoy MG, Maugeri F, Rodrigues MI, Freire DM, Castilho LR.

Bioresour Technol. 2009 Nov;100(21):5249-54. doi: 10.1016/j.biortech.2008.08.050. Epub 2009 Jun 26.

PMID:
19560339
29.

Production of yellow fever virus in microcarrier-based Vero cell cultures.

Souza MC, Freire MS, Schulze EA, Gaspar LP, Castilho LR.

Vaccine. 2009 Oct 30;27(46):6420-3. doi: 10.1016/j.vaccine.2009.06.023. Epub 2009 Jun 24.

PMID:
19559120
30.

Biocompatibility of acetazolamide pastes in the subcutaneous tissue of rats.

Mori GG, Moraes IG, Nunes DC, Castilho LR, Poi WR.

Braz Dent J. 2009;20(1):17-21.

31.

Evaluation of sixth grade primary schoolchildren's knowledge about avulsion and dental reimplantation.

Castilho LR, Sundefeld ML, de Andrade DF, Panzarini SR, Poi WR.

Dent Traumatol. 2009 Aug;25(4):429-32. doi: 10.1111/j.1600-9657.2008.00756.x. Epub 2009 May 6.

PMID:
19459922
32.

Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system.

Fernandes AM, Marinho PA, Sartore RC, Paulsen BS, Mariante RM, Castilho LR, Rehen SK.

Braz J Med Biol Res. 2009 Jun;42(6):515-22.

33.

Biocompatibility evaluation of alendronate paste in rat's subcutaneous tissue.

Mori GG, de Moraes IG, Nunes DC, Castilho LR, Poi WR, Capaldi ML.

Dent Traumatol. 2009 Apr;25(2):209-12. doi: 10.1111/j.1600-9657.2008.00731.x.

PMID:
19290902
34.

Avulsion of permanent teeth: analysis of the efficacy of na informative campaign for professionals from elementary schools.

Mori GG, Castilho LR, Nunes DC, Turcio KH, Molina RO.

J Appl Oral Sci. 2007 Dec;15(6):534-8.

35.

Separation of CHO cells using hydrocyclones.

Pinto RC, Medronho RA, Castilho LR.

Cytotechnology. 2008 Jan;56(1):57-67. doi: 10.1007/s10616-007-9108-x. Epub 2007 Nov 14.

36.

Production and regulation of lipase activity from Penicillium restrictum in submerged and solid-state fermentations.

de Azeredo LA, Gomes PM, Sant'Anna GL Jr, Castilho LR, Freire DM.

Curr Microbiol. 2007 May;54(5):361-5. Epub 2007 Apr 24.

PMID:
17457647
37.

Characterization of poly(3-hydroxybutyrate) produced by Cupriavidus necator in solid-state fermentation.

Oliveira FC, Dias ML, Castilho LR, Freire DM.

Bioresour Technol. 2007 Feb;98(3):633-8. Epub 2006 Mar 31.

PMID:
16580194
38.

High-yield Bacillus subtilis protease production by solid-state fermentation.

Soares VF, Castilho LR, Bon EP, Freire DM.

Appl Biochem Biotechnol. 2005 Spring;121-124:311-9.

PMID:
15917609
39.

Lipase production by solid-state fermentation: cultivation conditions and operation of tray and packed-bed bioreactors.

Gutarra ML, Cavalcanti ED, Castilho LR, Freire DM, Sant'Anna GL.

Appl Biochem Biotechnol. 2005 Spring;121-124:105-16.

PMID:
15917592
40.

Production of poly(3-hydroxybutyrate) by solid-state fermentation with Ralstonia eutropha.

Oliveira FC, Freire DM, Castilho LR.

Biotechnol Lett. 2004 Dec;26(24):1851-5.

PMID:
15672227
41.

CFD-aided design of a dynamic filter for mammalian cell separation.

Castilho LR, Anspach FB.

Biotechnol Bioeng. 2003 Sep 5;83(5):514-24.

PMID:
12827693
42.

Protease production by Streptomyces sp. isolated from Brazilian Cerrado soil: optimization of culture medium employing statistical experimental design.

De Azeredo LA, Castilho LR, Leite SG, Coelho RR, Freire D.

Appl Biochem Biotechnol. 2003 Spring;105 -108:749-55.

PMID:
12721412
43.

An integrated process for mammalian cell perfusion cultivation and product purification using a dynamic filter.

Castilho LR, Anspach FB, Deckwer WD.

Biotechnol Prog. 2002 Jul-Aug;18(4):776-81.

PMID:
12153312
44.

Cell retention devices for suspended-cell perfusion cultures.

Castilho LR, Medronho RA.

Adv Biochem Eng Biotechnol. 2002;74:129-69. Review.

PMID:
11991177
45.

Lipase production by Penicillium restrictum using solid waste of industrial babassu oil production as substrate.

Palma MB, Pinto AL, Gombert AK, Seitz KH, Kivatinitz SC, Castilho LR, Freire DM.

Appl Biochem Biotechnol. 2000 Spring;84-86:1137-45.

PMID:
10849864

Supplemental Content

Loading ...
Support Center