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Items: 24

1.

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation.

Castiello L, Zevini A, Vulpis E, Muscolini M, Ferrari M, Palermo E, Peruzzi G, Krapp C, Jakobsen M, Olagnier D, Zingoni A, Santoni A, Hiscott J.

Cancer Immunol Immunother. 2019 Aug 28. doi: 10.1007/s00262-019-02380-2. [Epub ahead of print]

PMID:
31463653
2.

Activation of latent HIV-1 T cell reservoirs with a combination of innate immune and epigenetic regulators.

Palermo E, Acchioni C, Di Carlo D, Zevini A, Muscolini M, Ferrari M, Castiello L, Virtuoso S, Borsetti A, Antonelli G, Turriziani O, Sgarbanti M, Hiscott J.

J Virol. 2019 Aug 14. pii: JVI.01194-19. doi: 10.1128/JVI.01194-19. [Epub ahead of print]

PMID:
31413127
3.

Clinical and Antitumor Immune Responses in Relapsed/Refractory Follicular Lymphoma Patients after Intranodal Injections of IFNα-Dendritic Cells and Rituximab: a Phase I Clinical Trial.

Cox MC, Castiello L, Mattei M, Santodonato L, D'Agostino G, Muraro E, Martorelli D, Lapenta C, Di Napoli A, Di Landro F, Cangemi M, Pavan A, Castaldo P, Hohaus S, Donati S, Montefiore E, Berdini C, Carlei D, Monque DM, Ruco L, Prosperi D, Tafuri A, Spadaro F, Sestili P, Spada M, Dolcetti R, Santini SM, Rozera C, Aricò E, Capone I, Belardelli F.

Clin Cancer Res. 2019 Sep 1;25(17):5231-5241. doi: 10.1158/1078-0432.CCR-19-0709. Epub 2019 Jun 6.

PMID:
31171545
4.

SIRT1 Modulates the Sensitivity of Prostate Cancer Cells to Vesicular Stomatitis Virus Oncolysis.

Muscolini M, Castiello L, Palermo E, Zevini A, Ferrari M, Olagnier D, Hiscott J.

J Virol. 2019 Jul 17;93(15). pii: e00626-19. doi: 10.1128/JVI.00626-19. Print 2019 Aug 1.

PMID:
31092575
5.

Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells.

Castiello L, Sestili P, Schiavoni G, Dattilo R, Monque DM, Ciaffoni F, Iezzi M, Lamolinara A, Sistigu A, Moschella F, Pacca AM, Macchia D, Ferrantini M, Zeuner A, Biffoni M, Proietti E, Belardelli F, Aricò E.

Cancer Immunol Res. 2018 Jun;6(6):658-670. doi: 10.1158/2326-6066.CIR-17-0675. Epub 2018 Apr 5.

6.

Impaired IFN-α-mediated signal in dendritic cells differentiates active from latent tuberculosis.

Parlato S, Chiacchio T, Salerno D, Petrone L, Castiello L, Romagnoli G, Canini I, Goletti D, Gabriele L.

PLoS One. 2018 Jan 10;13(1):e0189477. doi: 10.1371/journal.pone.0189477. eCollection 2018.

7.

Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients.

Castiello L, Sabatino M, Ren J, Terabe M, Khuu H, Wood LV, Berzofsky JA, Stroncek DF.

Clin Cancer Res. 2017 Jul 1;23(13):3352-3364. doi: 10.1158/1078-0432.CCR-16-2199. Epub 2017 Jan 10.

8.

TARP vaccination is associated with slowing in PSA velocity and decreasing tumor growth rates in patients with Stage D0 prostate cancer.

Wood LV, Fojo A, Roberson BD, Hughes MS, Dahut W, Gulley JL, Madan RA, Arlen PM, Sabatino M, Stroncek DF, Castiello L, Trepel JB, Lee MJ, Parnes HL, Steinberg SM, Terabe M, Wilkerson J, Pastan I, Berzofsky JA.

Oncoimmunology. 2016 Jul 1;5(8):e1197459. doi: 10.1080/2162402X.2016.1197459. eCollection 2016 Aug.

9.

Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus.

Olagnier D, Amatore D, Castiello L, Ferrari M, Palermo E, Diamond MS, Palamara AT, Hiscott J.

J Mol Biol. 2016 Aug 28;428(17):3429-48. doi: 10.1016/j.jmb.2016.04.024. Epub 2016 Apr 27. Review.

PMID:
27130436
10.

Social threat exposure in juvenile mice promotes cocaine-seeking by altering blood clotting and brain vasculature.

Lo Iacono L, Valzania A, Visco-Comandini F, Aricò E, Viscomi MT, Castiello L, Oddi D, D'Amato FR, Bisicchia E, Ermakova O, Puglisi-Allegra S, Carola V.

Addict Biol. 2017 Jul;22(4):911-922. doi: 10.1111/adb.12373. Epub 2016 Feb 12.

11.

Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma.

Rozera C, Cappellini GA, D'Agostino G, Santodonato L, Castiello L, Urbani F, Macchia I, Aricò E, Casorelli I, Sestili P, Montefiore E, Monque D, Carlei D, Napolitano M, Rizza P, Moschella F, Buccione C, Belli R, Proietti E, Pavan A, Marchetti P, Belardelli F, Capone I.

J Transl Med. 2015 May 2;13:139. doi: 10.1186/s12967-015-0473-5.

12.

Human bone marrow stromal cell confluence: effects on cell characteristics and methods of assessment.

Ren J, Wang H, Tran K, Civini S, Jin P, Castiello L, Feng J, Kuznetsov SA, Robey PG, Sabatino M, Stroncek DF.

Cytotherapy. 2015 Jul;17(7):897-911. doi: 10.1016/j.jcyt.2015.03.607. Epub 2015 Apr 14.

13.

Leukemia cells induce changes in human bone marrow stromal cells.

Civini S, Jin P, Ren J, Sabatino M, Castiello L, Jin J, Wang H, Zhao Y, Marincola F, Stroncek D.

J Transl Med. 2013 Dec 4;11:298. doi: 10.1186/1479-5876-11-298.

14.

Simplified process for the production of anti-CD19-CAR-engineered T cells.

Tumaini B, Lee DW, Lin T, Castiello L, Stroncek DF, Mackall C, Wayne A, Sabatino M.

Cytotherapy. 2013 Nov;15(11):1406-15. doi: 10.1016/j.jcyt.2013.06.003. Epub 2013 Aug 28.

15.

Intra-subject variability in human bone marrow stromal cell (BMSC) replicative senescence: molecular changes associated with BMSC senescence.

Ren J, Stroncek DF, Zhao Y, Jin P, Castiello L, Civini S, Wang H, Feng J, Tran K, Kuznetsov SA, Robey PG, Sabatino M.

Stem Cell Res. 2013 Nov;11(3):1060-73. doi: 10.1016/j.scr.2013.07.005. Epub 2013 Jul 27.

16.

Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation.

Fowler DH, Mossoba ME, Steinberg SM, Halverson DC, Stroncek D, Khuu HM, Hakim FT, Castiello L, Sabatino M, Leitman SF, Mariotti J, Gea-Banacloche JC, Sportes C, Hardy NM, Hickstein DD, Pavletic SZ, Rowley S, Goy A, Donato M, Korngold R, Pecora A, Levine BL, June CH, Gress RE, Bishop MR.

Blood. 2013 Apr 11;121(15):2864-74. doi: 10.1182/blood-2012-08-446872. Epub 2013 Feb 20.

17.

Differential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cells.

Castiello L, Mossoba M, Viterbo A, Sabatino M, Fellowes V, Foley JE, Winterton M, Halverson DC, Civini S, Jin P, Fowler DH, Stroncek DF.

Cytotherapy. 2013 May;15(5):598-609. doi: 10.1016/j.jcyt.2012.12.008. Epub 2013 Jan 24.

18.

Quality controls in cellular immunotherapies: rapid assessment of clinical grade dendritic cells by gene expression profiling.

Castiello L, Sabatino M, Zhao Y, Tumaini B, Ren J, Ping J, Wang E, Wood LV, Marincola FM, Puri RK, Stroncek DF.

Mol Ther. 2013 Feb;21(2):476-84. doi: 10.1038/mt.2012.89. Epub 2012 Nov 13. Erratum in: Mol Ther. 2013 Feb;21(2):495.

19.

15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.

Clayberger C, Finn MW, Wang T, Saini R, Wilson C, Barr VA, Sabatino M, Castiello L, Stroncek D, Krensky AM.

J Immunol. 2012 Jun 15;188(12):6119-26. doi: 10.4049/jimmunol.1200570. Epub 2012 May 14.

20.

Concomitant detection of IFNα signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNα-treated subjects at early times after repeated local cytokine treatments.

Aricò E, Castiello L, Urbani F, Rizza P, Panelli MC, Wang E, Marincola FM, Belardelli F.

J Transl Med. 2011 May 17;9:67. doi: 10.1186/1479-5876-9-67.

21.

15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level.

Castiello L, Stroncek DF, Finn MW, Wang E, Marincola FM, Clayberger C, Krensky AM, Sabatino M.

J Transl Med. 2011 Apr 18;9:41. doi: 10.1186/1479-5876-9-41.

22.

Monocyte-derived DC maturation strategies and related pathways: a transcriptional view.

Castiello L, Sabatino M, Jin P, Clayberger C, Marincola FM, Krensky AM, Stroncek DF.

Cancer Immunol Immunother. 2011 Apr;60(4):457-66. doi: 10.1007/s00262-010-0954-6. Epub 2011 Jan 22. Review.

23.

Quality assessment of cellular therapies: the emerging role of molecular assays.

Stroncek DF, Jin P, Ren J, Feng J, Castiello L, Civini S, Wang E, Marincola FM, Sabatino M.

Korean J Hematol. 2010 Mar;45(1):14-22. doi: 10.5045/kjh.2010.45.1.14. Epub 2010 Mar 31.

24.

Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways.

Veroni C, Gabriele L, Canini I, Castiello L, Coccia E, Remoli ME, Columba-Cabezas S, Aricò E, Aloisi F, Agresti C.

Mol Cell Neurosci. 2010 Nov;45(3):234-44. doi: 10.1016/j.mcn.2010.06.014. Epub 2010 Jun 28.

PMID:
20600925

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