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TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella.

Thomas L, Bouhouche K, Whitfield M, Thouvenin G, Coste A, Louis B, Szymanski C, Bequignon E, Papon JF, Castelli M, Lemullois M, Dhalluin X, Drouin-Garraud V, Montantin G, Tissier S, Duquesnoy P, Copin B, Dastot F, Couvet S, Barbotin AL, Faucon C, Honore I, Maitre B, Beydon N, Tamalet A, Rives N, Koll F, Escudier E, Tassin AM, Touré A, Mitchell V, Amselem S, Legendre M.

Am J Hum Genet. 2020 Jan 22. pii: S0002-9297(19)30474-4. doi: 10.1016/j.ajhg.2019.12.010. [Epub ahead of print]


Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe.

Miliano C, Marti M, Pintori N, Castelli MP, Tirri M, Arfè R, De Luca MA.

Front Pharmacol. 2019 Dec 12;10:1406. doi: 10.3389/fphar.2019.01406. eCollection 2019.


HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53-dependent mitochondrial apoptosis.

Castelli M, Piobbico D, Chiacchiaretta M, Brunacci C, Pieroni S, Bartoli D, Gargaro M, Fallarino F, Puccetti P, Soddu S, Della-Fazia MA, Servillo G.

EMBO Rep. 2019 Dec 23:e48073. doi: 10.15252/embr.201948073. [Epub ahead of print]


The pharmacology and therapeutic applications of monoclonal antibodies.

Castelli MS, McGonigle P, Hornby PJ.

Pharmacol Res Perspect. 2019 Dec;7(6):e00535. doi: 10.1002/prp2.535. Review.


Platelet-Derived Extracellular Vesicles as Target of Antiplatelet Agents. What Is the Evidence?

Taus F, Meneguzzi A, Castelli M, Minuz P.

Front Pharmacol. 2019 Nov 8;10:1256. doi: 10.3389/fphar.2019.01256. eCollection 2019. Review.


Bloodstream infections caused by Escherichia coli carrying mcr-1 gene in hospitalized patients in northern Italy from 2012 to 2018.

Mariani B, Corbella M, Merla C, Tallarita M, Piralla A, Girello A, Castelli M, Bracchi C, Marone P, Cambieri P.

Infection. 2019 Nov 22. doi: 10.1007/s15010-019-01377-4. [Epub ahead of print]


Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness.

Nigro EA, Distefano G, Chiaravalli M, Matafora V, Castelli M, Pesenti Gritti A, Bachi A, Boletta A.

Sci Rep. 2019 Nov 12;9(1):16640. doi: 10.1038/s41598-019-53061-0.


Machine learning techniques to predict the effectiveness of music therapy: A randomized controlled trial.

Raglio A, Imbriani M, Imbriani C, Baiardi P, Manzoni S, Gianotti M, Castelli M, Vanneschi L, Vico F, Manzoni L.

Comput Methods Programs Biomed. 2019 Oct 29;185:105160. doi: 10.1016/j.cmpb.2019.105160. [Epub ahead of print]


Prevalence of mild hyponatremia and its association with falls in older adults admitted to an emergency geriatric medicine unit (the MUPA unit).

Boyer S, Gayot C, Bimou C, Mergans T, Kajeu P, Castelli M, Dantoine T, Tchalla A.

BMC Geriatr. 2019 Oct 15;19(1):265. doi: 10.1186/s12877-019-1282-0.


Chemical composition of Schinus areira essential oil and antimicrobial action against Staphylococcus aureus.

Cutro AC, Castelli MV, López SN, Rosales MA, Hollmann A, Rodriguez SA.

Nat Prod Res. 2019 Oct 12:1-6. doi: 10.1080/14786419.2019.1675065. [Epub ahead of print]


Politics as an Explanation to the Health Divide in Different Settings: A Comparative Study of England and Ghana.

Alhassan JAK, Castelli M.

Int J Health Serv. 2020 Jan;50(1):110-122. doi: 10.1177/0020731419876786. Epub 2019 Sep 18. No abstract available.


Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa.

Collu R, Scherma M, Piscitelli F, Giunti E, Satta V, Castelli MP, Verde R, Fratta W, Bisogno T, Fadda P.

Int J Eat Disord. 2019 Nov;52(11):1251-1262. doi: 10.1002/eat.23157. Epub 2019 Aug 27.


Managing uncertainty in medicine quality in Ghana: The cognitive and affective basis of trust in a high-risk, low-regulation context.

Hamill H, Hampshire K, Mariwah S, Amoako-Sakyi D, Kyei A, Castelli M.

Soc Sci Med. 2019 Aug;234:112369. doi: 10.1016/j.socscimed.2019.112369. Epub 2019 Jun 12.


Antibacterial activity of prenylated benzopyrans from Peperomia obtusifolia (Piperaceae).

Ruiz Mostacero N, Castelli MV, Cutró AC, Hollmann A, Batista JM Jr, Furlan M, Valles J, Fulgueira CL, López SN.

Nat Prod Res. 2019 Jun 14:1-5. doi: 10.1080/14786419.2019.1628751. [Epub ahead of print]


Tissue tropism and metabolic pathways of Midichloria mitochondrii suggest tissue-specific functions in the symbiosis with Ixodes ricinus.

Olivieri E, Epis S, Castelli M, Varotto Boccazzi I, Romeo C, Desirò A, Bazzocchi C, Bandi C, Sassera D.

Ticks Tick Borne Dis. 2019 Aug;10(5):1070-1077. doi: 10.1016/j.ttbdis.2019.05.019. Epub 2019 Jun 3.


Comparative Analysis of the Two Acinetobacter baumannii Multilocus Sequence Typing (MLST) Schemes.

Gaiarsa S, Batisti Biffignandi G, Esposito EP, Castelli M, Jolley KA, Brisse S, Sassera D, Zarrilli R.

Front Microbiol. 2019 May 3;10:930. doi: 10.3389/fmicb.2019.00930. eCollection 2019.


Predisposition to Alcohol Drinking and Alcohol Consumption Alter Expression of Calcitonin Gene-Related Peptide, Neuropeptide Y, and Microglia in Bed Nucleus of Stria Terminalis in a Subnucleus-Specific Manner.

Rossetti I, Zambusi L, Maccioni P, Sau R, Provini L, Castelli MP, Gonciarz K, Colombo G, Morara S.

Front Cell Neurosci. 2019 Apr 30;13:158. doi: 10.3389/fncel.2019.00158. eCollection 2019.


Deianiraea, an extracellular bacterium associated with the ciliate Paramecium, suggests an alternative scenario for the evolution of Rickettsiales.

Castelli M, Sabaneyeva E, Lanzoni O, Lebedeva N, Floriano AM, Gaiarsa S, Benken K, Modeo L, Bandi C, Potekhin A, Sassera D, Petroni G.

ISME J. 2019 Sep;13(9):2280-2294. doi: 10.1038/s41396-019-0433-9. Epub 2019 May 9.


The Fine Tuning of Drp1-Dependent Mitochondrial Remodeling and Autophagy Controls Neuronal Differentiation.

Vantaggiato C, Castelli M, Giovarelli M, Orso G, Bassi MT, Clementi E, De Palma C.

Front Cell Neurosci. 2019 Apr 4;13:120. doi: 10.3389/fncel.2019.00120. eCollection 2019.


Cell-to-Cell Spread Blocking Activity Is Extremely Limited in the Sera of Herpes Simplex Virus 1 (HSV-1)- and HSV-2-Infected Subjects.

Criscuolo E, Castelli M, Diotti RA, Amato V, Burioni R, Clementi M, Ambrosi A, Mancini N, Clementi N.

J Virol. 2019 May 15;93(11). pii: e00070-19. doi: 10.1128/JVI.00070-19. Print 2019 Jun 1.


Industrial uses of phospholipases: current state and future applications.

Cerminati S, Paoletti L, Aguirre A, Peirú S, Menzella HG, Castelli ME.

Appl Microbiol Biotechnol. 2019 Mar;103(6):2571-2582. doi: 10.1007/s00253-019-09658-6. Epub 2019 Feb 7. Review.


Diversity and environmental distribution of the cosmopolitan endosymbiont "Candidatus Megaira".

Lanzoni O, Sabaneyeva E, Modeo L, Castelli M, Lebedeva N, Verni F, Schrallhammer M, Potekhin A, Petroni G.

Sci Rep. 2019 Feb 4;9(1):1179. doi: 10.1038/s41598-018-37629-w.


Weighted Hierarchical Grammatical Evolution.

Bartoli A, Castelli M, Medvet E.

IEEE Trans Cybern. 2020 Feb;50(2):476-488. doi: 10.1109/TCYB.2018.2876563. Epub 2018 Nov 6.


Effects of High-intensity Robot-assisted Hand Training on Upper Limb Recovery and Muscle Activity in Individuals With Multiple Sclerosis: A Randomized, Controlled, Single-Blinded Trial.

Gandolfi M, Valè N, Dimitrova EK, Mazzoleni S, Battini E, Benedetti MD, Gajofatto A, Ferraro F, Castelli M, Camin M, Filippetti M, De Paoli C, Chemello E, Picelli A, Corradi J, Waldner A, Saltuari L, Smania N.

Front Neurol. 2018 Oct 24;9:905. doi: 10.3389/fneur.2018.00905. eCollection 2018.


Role of IL-17RA in the proliferative priming of hepatocytes in liver regeneration.

Piobbico D, Bartoli D, Pieroni S, De Luca A, Castelli M, Romani L, Servillo G, Della-Fazia MA.

Cell Cycle. 2018;17(21-22):2423-2435. doi: 10.1080/15384101.2018.1542893. Epub 2018 Nov 11.


The Hidden World of Rickettsiales Symbionts: "Candidatus Spectririckettsia obscura," a Novel Bacterium Found in Brazilian and Indian Paramecium caudatum.

Castelli M, Serra V, Senra MVX, Basuri CK, Soares CAG, Fokin SI, Modeo L, Petroni G.

Microb Ecol. 2019 Apr;77(3):748-758. doi: 10.1007/s00248-018-1243-8. Epub 2018 Aug 13.


Iron-based trinuclear metal-organic nanostructures on a surface with local charge accumulation.

Krull C, Castelli M, Hapala P, Kumar D, Tadich A, Capsoni M, Edmonds MT, Hellerstedt J, Burke SA, Jelinek P, Schiffrin A.

Nat Commun. 2018 Aug 10;9(1):3211. doi: 10.1038/s41467-018-05543-4.


ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis.

Vantaggiato C, Panzeri E, Castelli M, Citterio A, Arnoldi A, Santorelli FM, Liguori R, Scarlato M, Musumeci O, Toscano A, Clementi E, Bassi MT.

Autophagy. 2019 Jan;15(1):34-57. doi: 10.1080/15548627.2018.1507438. Epub 2018 Sep 13.


Improving eQTL Analysis Using a Machine Learning Approach for Data Integration: A Logistic Model Tree Solution.

Beretta S, Castelli M, Gonçalves I, Kel I, Giansanti V, Merelli I.

J Comput Biol. 2018 Oct;25(10):1091-1105. doi: 10.1089/cmb.2017.0167. Epub 2018 Jul 27.


The persistent problem of integrated care in English NHS hospitals.

Erskine J, Castelli M, Hunter D, Hungin A.

J Health Organ Manag. 2018 Jun 18;32(4):532-544. doi: 10.1108/JHOM-01-2018-0020. Epub 2018 Jun 29.


Designing Optoelectronic Properties by On-Surface Synthesis: Formation and Electronic Structure of an Iron-Terpyridine Macromolecular Complex.

Schiffrin A, Capsoni M, Farahi G, Wang CG, Krull C, Castelli M, Roussy T, Cochrane KA, Yin Y, Medhekar NV, Fuhrer M, Shaw AQ, Ji W, Burke SA.

ACS Nano. 2018 Jul 24;12(7):6545-6553. doi: 10.1021/acsnano.8b01026. Epub 2018 Jun 18.


The βγ-crystallin domain of Lysinibacillus sphaericus phosphatidylinositol phospholipase C plays a central role in protein stability.

Cerminati S, Paoletti L, Peirú S, Menzella HG, Castelli ME.

Appl Microbiol Biotechnol. 2018 Aug;102(16):6997-7005. doi: 10.1007/s00253-018-9136-9. Epub 2018 Jun 16.


In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5.

Beggiato S, Borelli AC, Tomasini MC, Castelli MP, Pintori N, Cacciaglia R, Loche A, Ferraro L.

Front Pharmacol. 2018 Apr 5;9:327. doi: 10.3389/fphar.2018.00327. eCollection 2018.


A Parallel Multiobjective Metaheuristic for Multiple Sequence Alignment.

Rubio-Largo Á, Castelli M, Vanneschi L, Vega-Rodríguez MA.

J Comput Biol. 2018 Sep;25(9):1009-1022. doi: 10.1089/cmb.2018.0031. Epub 2018 Apr 19.


The Genome Sequence of "Candidatus Fokinia solitaria": Insights on Reductive Evolution in Rickettsiales.

Floriano AM, Castelli M, Krenek S, Berendonk TU, Bazzocchi C, Petroni G, Sassera D.

Genome Biol Evol. 2018 Apr 1;10(4):1120-1126. doi: 10.1093/gbe/evy072.


The production, properties, and applications of thermostable steryl glucosidases.

Aguirre A, Eberhardt F, Hails G, Cerminati S, Castelli ME, Rasia RM, Paoletti L, Menzella HG, Peiru S.

World J Microbiol Biotechnol. 2018 Feb 21;34(3):40. doi: 10.1007/s11274-018-2423-x. Review.


Limited Access to a High Fat Diet Alters Endocannabinoid Tone in Female Rats.

Satta V, Scherma M, Piscitelli F, Usai P, Castelli MP, Bisogno T, Fratta W, Fadda P.

Front Neurosci. 2018 Feb 2;12:40. doi: 10.3389/fnins.2018.00040. eCollection 2018.


Phylogenetic relationships among endosymbiotic R-body producer: Bacteria providing their host the killer trait.

Schrallhammer M, Castelli M, Petroni G.

Syst Appl Microbiol. 2018 May;41(3):213-220. doi: 10.1016/j.syapm.2018.01.005. Epub 2018 Feb 14.


Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.

Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C Jr.

Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31.


Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a Gαi/o protein inhibitor.

Porcu A, Melis M, Turecek R, Ullrich C, Mocci I, Bettler B, Gessa GL, Castelli MP.

Neuropharmacology. 2018 May 1;133:107-120. doi: 10.1016/j.neuropharm.2018.01.024.


Synergy evaluation of anti-Herpes Simplex Virus type 1 and 2 compounds acting on different steps of virus life cycle.

Criscuolo E, Clementi N, Mancini N, Burioni R, Miduri M, Castelli M, Clementi M.

Antiviral Res. 2018 Mar;151:71-77. doi: 10.1016/j.antiviral.2018.01.009. Epub 2018 Jan 31.


Host and symbiont intraspecific variability: The case of Paramecium calkinsi and "Candidatus Trichorickettsia mobilis".

Sabaneyeva E, Castelli M, Szokoli F, Benken K, Lebedeva N, Salvetti A, Schweikert M, Fokin S, Petroni G.

Eur J Protistol. 2018 Feb;62:79-94. doi: 10.1016/j.ejop.2017.12.002. Epub 2017 Dec 9.


Effect of a Rivaroxaban Patient Assistance Kit (R-PAK) for Patients Discharged With Rivaroxaban: A Randomized Controlled Trial.

Castelli MR, Saint CA, Nuziale BT, Stern GM, Stacy ZA, Crannage AJ, Pitlick JM.

Hosp Pharm. 2017 Jul;52(7):496-501. doi: 10.1177/0018578717721105. Epub 2017 Jul 25.


Sex determination mode does not affect body or genital development of the central bearded dragon (Pogona vitticeps).

Whiteley SL, Holleley CE, Ruscoe WA, Castelli M, Whitehead DL, Lei J, Georges A, Weisbecker V.

Evodevo. 2017 Dec 4;8:25. doi: 10.1186/s13227-017-0087-5. eCollection 2017.


"Strange animals": hybrid organisations in health care.

Powell M, Castelli M.

J Health Organ Manag. 2017 Oct 9;31(7-8):746-762. doi: 10.1108/JHOM-04-2017-0068.


Comparison of hospital length of stay in patients treated with non-vitamin K oral anticoagulants or parenteral agents plus warfarin for venous thromboembolism.

Saint CA, Castelli MR, Crannage AJ, Stacy ZA, Hennessey EK.

SAGE Open Med. 2017 Jul 18;5:2050312117719628. doi: 10.1177/2050312117719628. eCollection 2017.


Reducing Alignment Time Complexity of Ultra-Large Sets of Sequences.

Rubio-Largo Á, Vanneschi L, Castelli M, Vega-Rodríguez MA.

J Comput Biol. 2017 Nov;24(11):1144-1154. doi: 10.1089/cmb.2017.0097. Epub 2017 Jul 7.


Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice.

Benoit B, Meugnier E, Castelli M, Chanon S, Vieille-Marchiset A, Durand C, Bendridi N, Pesenti S, Monternier PA, Durieux AC, Freyssenet D, Rieusset J, Lefai E, Vidal H, Ruzzin J.

Nat Med. 2017 Aug;23(8):990-996. doi: 10.1038/nm.4363. Epub 2017 Jun 26.


Embolization of ovarian vein for pelvic congestion syndrome with ethylene vinyl alcohol copolymer (Onyx®).

Marcelin C, Izaaryene J, Castelli M, Barral PA, Jacquier A, Vidal V, Bartoli JM.

Diagn Interv Imaging. 2017 Dec;98(12):843-848. doi: 10.1016/j.diii.2017.05.011. Epub 2017 Jun 22.


Altered expression of signalling lymphocyte activation molecule receptors in T-cells from lupus nephritis patients-a potential biomarker of disease activity.

Stratigou V, Doyle AF, Carlucci F, Stephens L, Foschi V, Castelli M, McKenna N, Cook HT, Lightstone L, Cairns TD, Pickering MC, Botto M.

Rheumatology (Oxford). 2017 Jul 1;56(7):1206-1216. doi: 10.1093/rheumatology/kex078.

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