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Items: 1 to 50 of 138

1.

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.

Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML.

J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24.

PMID:
30078314
2.

Artificial Sphincters to Manage Urinary Incontinence: A Review.

Marziale L, Lucarini G, Mazzocchi T, Gruppioni E, Castellano S, Davalli A, Sacchetti R, Pistolesi D, Ricotti L, Menciassi A.

Artif Organs. 2018 Aug 3. doi: 10.1111/aor.13164. [Epub ahead of print] Review.

PMID:
30074617
3.

Broadly conserved Na+-binding site in the N-lobe of prokaryotic multidrug MATE transporters.

Ficici E, Zhou W, Castellano S, Faraldo-Gómez JD.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6172-E6181. doi: 10.1073/pnas.1802080115. Epub 2018 Jun 18.

PMID:
29915058
4.

Vascular access clinic results before and after implementing a multidisciplinary approach adding routine Doppler ultrasound.

Aragoncillo Sauco I, Ligero Ramos JM, Vega Martínez A, Morales Muñoz ÁL, Abad Estébanez S, Macías Carmona N, Ruiz Chiriboga D, García Pajares R, Cervera Bravo T, López-Gómez JM, Manzano Grossi S, Menéndez Sánchez E, Río Gomez J, García Prieto AM, Linares Grávalos T, Garcia Boyano F, Reparaz Asensio LM, Albalate Ramón M, de Sequera Ortiz P, Gil Casares B, Ampuero Mencía J, Castellano S, Martín Pérez B, Conty JLM, Santos Garcia A, Luño Fernandez J.

Nefrologia. 2018 Jun 11. pii: S0211-6995(18)30073-0. doi: 10.1016/j.nefro.2018.04.003. [Epub ahead of print] English, Spanish.

5.

The S-Finger: A Synergetic Externally Powered Digit With Tactile Sensing and Feedback.

Imbinto I, Montagnani F, Bacchereti M, Cipriani C, Davalli A, Sacchetti R, Gruppioni E, Castellano S, Controzzi M.

IEEE Trans Neural Syst Rehabil Eng. 2018 Jun;26(6):1264-1271. doi: 10.1109/TNSRE.2018.2829183.

PMID:
29877851
6.

The genomics of selenium: Its past, present and future.

Davy T, Castellano S.

Biochim Biophys Acta Gen Subj. 2018 May 30. pii: S0304-4165(18)30152-1. doi: 10.1016/j.bbagen.2018.05.020. [Epub ahead of print] Review.

PMID:
29859258
7.

Dietary Polyphenol Intake and Depression: Results from the Mediterranean Healthy Eating, Lifestyle and Aging (MEAL) Study.

Godos J, Castellano S, Ray S, Grosso G, Galvano F.

Molecules. 2018 Apr 24;23(5). pii: E999. doi: 10.3390/molecules23050999.

8.

Distinct Patterns of Selection in Selenium-Dependent Genes between Land and Aquatic Vertebrates.

Sarangi GK, Romagné F, Castellano S.

Mol Biol Evol. 2018 Jul 1;35(7):1744-1756. doi: 10.1093/molbev/msy070.

PMID:
29669130
9.

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.

Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E.

Oncotarget. 2017 Aug 2;8(40):68557-68570. doi: 10.18632/oncotarget.19782. eCollection 2017 Sep 15.

10.

Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO).

Milite C, Barresi E, Da Pozzo E, Costa B, Viviano M, Porta A, Messere A, Sbardella G, Da Settimo F, Novellino E, Cosconati S, Castellano S, Taliani S, Martini C.

J Med Chem. 2017 Sep 28;60(18):7897-7909. doi: 10.1021/acs.jmedchem.7b01031. Epub 2017 Sep 15.

PMID:
28858490
11.

Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn.

Yang D, Giragossian C, Castellano S, Lasaro M, Xiao H, Saraf H, Hess Kenny C, Rybina I, Huang ZF, Ahlberg J, Bigwarfe T, Myzithras M, Waltz E, Roberts S, Kroe-Barrett R, Singh S.

MAbs. 2017 Oct;9(7):1105-1117. doi: 10.1080/19420862.2017.1359455. Epub 2017 Aug 8.

12.

Rotator cuff degeneration of the healthy shoulder in patients with unilateral arm amputation is not worsened by overuse.

Gumina S, Candela V, Mariani L, Venditto T, Catalano C, Castellano S, Santilli V, Giannicola G, Castagna A.

Knee Surg Sports Traumatol Arthrosc. 2018 Jan;26(1):182-187. doi: 10.1007/s00167-017-4619-2. Epub 2017 Jul 13.

PMID:
28707116
13.

Determination of genetic relatedness from low-coverage human genome sequences using pedigree simulations.

Martin MD, Jay F, Castellano S, Slatkin M.

Mol Ecol. 2017 Aug;26(16):4145-4157. doi: 10.1111/mec.14188. Epub 2017 Jul 7.

PMID:
28543951
14.

Developing Spindlin1 small-molecule inhibitors by using protein microarrays.

Bae N, Viviano M, Su X, Lv J, Cheng D, Sagum C, Castellano S, Bai X, Johnson C, Khalil MI, Shen J, Chen K, Li H, Sbardella G, Bedford MT.

Nat Chem Biol. 2017 Jul;13(7):750-756. doi: 10.1038/nchembio.2377. Epub 2017 May 15.

15.

Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation.

Dobson THW, Hatcher RJ, Swaminathan J, Das CM, Shaik S, Tao RH, Milite C, Castellano S, Taylor PH, Sbardella G, Gopalakrishnan V.

Mol Cancer Res. 2017 Aug;15(8):1073-1084. doi: 10.1158/1541-7786.MCR-16-0424. Epub 2017 May 8.

16.

N-Pyrrylarylsulfones with High Therapeutic Potential.

Famiglini V, Castellano S, Silvestri R.

Molecules. 2017 Mar 9;22(3). pii: E434. doi: 10.3390/molecules22030434. Review.

17.

11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.

Ikawa M, Lohith TG, Shrestha S, Telu S, Zoghbi SS, Castellano S, Taliani S, Da Settimo F, Fujita M, Pike VW, Innis RB; Biomarkers Consortium Radioligand Project Team.

J Nucl Med. 2017 Feb;58(2):320-325. doi: 10.2967/jnumed.116.178996. Epub 2016 Nov 17.

18.

Chimpanzee genomic diversity reveals ancient admixture with bonobos.

de Manuel M, Kuhlwilm M, Frandsen P, Sousa VC, Desai T, Prado-Martinez J, Hernandez-Rodriguez J, Dupanloup I, Lao O, Hallast P, Schmidt JM, Heredia-Genestar JM, Benazzo A, Barbujani G, Peter BM, Kuderna LF, Casals F, Angedakin S, Arandjelovic M, Boesch C, Kühl H, Vigilant L, Langergraber K, Novembre J, Gut M, Gut I, Navarro A, Carlsen F, Andrés AM, Siegismund HR, Scally A, Excoffier L, Tyler-Smith C, Castellano S, Xue Y, Hvilsom C, Marques-Bonet T.

Science. 2016 Oct 28;354(6311):477-481. Epub 2016 Oct 27.

19.

Selective Serotonin Reuptake Inhibitors and Serotonin and Noradrenaline Reuptake Inhibitors Improve Cognitive Function in Partial Responders Depressed Patients: Results from a Prospective Observational Cohort Study.

Castellano S, Ventimiglia A, Salomone S, Ventimiglia A, De Vivo S, Signorelli MS, Bellelli E, Santagati M, Cantarella RA, Fazio E, Aguglia E, Drago F, Di Nuovo S, Caraci F.

CNS Neurol Disord Drug Targets. 2016;15(10):1290-1298.

PMID:
27712575
20.

The emerging role of lysine methyltransferase SETD8 in human diseases.

Milite C, Feoli A, Viviano M, Rescigno D, Cianciulli A, Balzano AL, Mai A, Castellano S, Sbardella G.

Clin Epigenetics. 2016 Sep 22;8:102. eCollection 2016. Review.

21.

Sleep quality and duration is related with diet and obesity in young adolescent living in Sicily, Southern Italy.

Ferranti R, Marventano S, Castellano S, Giogianni G, Nolfo F, Rametta S, Matalone M, Mistretta A.

Sleep Sci. 2016 Apr-Jun;9(2):117-22. doi: 10.1016/j.slsci.2016.04.003. Epub 2016 Apr 14.

22.

Selenoprotein Gene Nomenclature.

Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonović M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y.

J Biol Chem. 2016 Nov 11;291(46):24036-24040. Epub 2016 Sep 19.

23.

Dietary n-3 PUFA, fish consumption and depression: A systematic review and meta-analysis of observational studies.

Grosso G, Micek A, Marventano S, Castellano S, Mistretta A, Pajak A, Galvano F.

J Affect Disord. 2016 Nov 15;205:269-281. doi: 10.1016/j.jad.2016.08.011. Epub 2016 Aug 16. Review.

PMID:
27544316
24.

Role of anthropometric factors, self-perception, and diet on weight misperception among young adolescents: a cross-sectional study.

Buscemi S, Marventano S, Castellano S, Nolfo F, Rametta S, Giorgianni G, Matalone M, Marranzano M, Mistretta A.

Eat Weight Disord. 2018 Feb;23(1):107-115. doi: 10.1007/s40519-016-0306-4. Epub 2016 Aug 9.

PMID:
27502108
25.

Identification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach.

Chini MG, Malafronte N, Vaccaro MC, Gualtieri MJ, Vassallo A, Vasaturo M, Castellano S, Milite C, Leone A, Bifulco G, De Tommasi N, Dal Piaz F.

Chemistry. 2016 Sep 5;22(37):13236-50. doi: 10.1002/chem.201602242. Epub 2016 Aug 5.

PMID:
27492719
26.

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation.

Iulita MF, Ower A, Barone C, Pentz R, Gubert P, Romano C, Cantarella RA, Elia F, Buono S, Recupero M, Romano C, Castellano S, Bosco P, Di Nuovo S, Drago F, Caraci F, Cuello AC.

Alzheimers Dement. 2016 Nov;12(11):1132-1148. doi: 10.1016/j.jalz.2016.05.001. Epub 2016 Jul 21.

PMID:
27452424
27.

Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors.

Milite C, Feoli A, Viviano M, Rescigno D, Mai A, Castellano S, Sbardella G.

ChemMedChem. 2016 Aug 19;11(16):1680-5. doi: 10.1002/cmdc.201600272. Epub 2016 Jul 14. Review.

PMID:
27411844
28.

Risk identification in haemodialysis patients by appropriate body composition assessment.

Castellano S, Palomares I, Moissl U, Chamney P, Carretero D, Crespo A, Morente C, Ribera L, Wabel P, Ramos R, Merello JI.

Nefrologia. 2016 May-Jun;36(3):268-74. doi: 10.1016/j.nefro.2016.01.007. Epub 2016 Apr 18. English, Spanish.

29.

The Divergence of Neandertal and Modern Human Y Chromosomes.

Mendez FL, Poznik GD, Castellano S, Bustamante CD.

Am J Hum Genet. 2016 Apr 7;98(4):728-34. doi: 10.1016/j.ajhg.2016.02.023.

30.

Ancient gene flow from early modern humans into Eastern Neanderthals.

Kuhlwilm M, Gronau I, Hubisz MJ, de Filippo C, Prado-Martinez J, Kircher M, Fu Q, Burbano HA, Lalueza-Fox C, de la Rasilla M, Rosas A, Rudan P, Brajkovic D, Kucan Ž, Gušic I, Marques-Bonet T, Andrés AM, Viola B, Pääbo S, Meyer M, Siepel A, Castellano S.

Nature. 2016 Feb 25;530(7591):429-33. doi: 10.1038/nature16544. Epub 2016 Feb 17.

31.

Preys' exploitation of predators' fear: when the caterpillar plays the Gruffalo.

Castellano S, Cermelli P.

Proc Biol Sci. 2015 Dec 7;282(1820):20151786. doi: 10.1098/rspb.2015.1786.

32.

Coffee, tea, caffeine and risk of depression: A systematic review and dose-response meta-analysis of observational studies.

Grosso G, Micek A, Castellano S, Pajak A, Galvano F.

Mol Nutr Food Res. 2016 Jan;60(1):223-34. doi: 10.1002/mnfr.201500620. Epub 2015 Nov 23. Review.

PMID:
26518745
33.

A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter?

Marventano S, Kolacz P, Castellano S, Galvano F, Buscemi S, Mistretta A, Grosso G.

Int J Food Sci Nutr. 2015;66(6):611-22. doi: 10.3109/09637486.2015.1077790. Epub 2015 Aug 26. Review.

PMID:
26307560
34.

Nucleated erythrocytes in blood smears of dogs undergoing chemotherapy.

Moretti P, Giordano A, Stefanello D, Ferrari R, Castellano S, Paltrinieri S.

Vet Comp Oncol. 2017 Mar;15(1):215-225. doi: 10.1111/vco.12156. Epub 2015 Jun 25.

PMID:
26109175
35.

CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli.

Franek M, Legartová S, Suchánková J, Milite C, Castellano S, Sbardella G, Kozubek S, Bártová E.

Physiol Res. 2015;64(5):769-82. Epub 2015 Jun 5.

36.

Genetic adaptation to levels of dietary selenium in recent human history.

White L, Romagné F, Müller E, Erlebach E, Weihmann A, Parra G, Andrés AM, Castellano S.

Mol Biol Evol. 2015 Jun;32(6):1507-18. doi: 10.1093/molbev/msv043. Epub 2015 Mar 3.

PMID:
25739735
37.

A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach.

Milite C, Feoli A, Sasaki K, La Pietra V, Balzano AL, Marinelli L, Mai A, Novellino E, Castellano S, Tosco A, Sbardella G.

J Med Chem. 2015 Mar 26;58(6):2779-98. doi: 10.1021/jm5019687. Epub 2015 Mar 10.

PMID:
25730130
38.

Clinical, analytical and bioimpedance characteristics of persistently overhydrated haemodialysis patients.

Castellano S, Palomares I, Molina M, Pérez-García R, Aljama P, Ramos R, Merello JI.

Nefrologia. 2014 Nov 17;34(6):716-23. doi: 10.3265/Nefrologia.pre2014.Sep.12468. English, Spanish.

39.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF.

Castellano S, Milite C, Feoli A, Viviano M, Mai A, Novellino E, Tosco A, Sbardella G.

ChemMedChem. 2015 Jan;10(1):144-57. doi: 10.1002/cmdc.201402371. Epub 2014 Oct 21.

PMID:
25333655
40.

Ancient human genomes suggest three ancestral populations for present-day Europeans.

Lazaridis I, Patterson N, Mittnik A, Renaud G, Mallick S, Kirsanow K, Sudmant PH, Schraiber JG, Castellano S, Lipson M, Berger B, Economou C, Bollongino R, Fu Q, Bos KI, Nordenfelt S, Li H, de Filippo C, Prüfer K, Sawyer S, Posth C, Haak W, Hallgren F, Fornander E, Rohland N, Delsate D, Francken M, Guinet JM, Wahl J, Ayodo G, Babiker HA, Bailliet G, Balanovska E, Balanovsky O, Barrantes R, Bedoya G, Ben-Ami H, Bene J, Berrada F, Bravi CM, Brisighelli F, Busby GB, Cali F, Churnosov M, Cole DE, Corach D, Damba L, van Driem G, Dryomov S, Dugoujon JM, Fedorova SA, Gallego Romero I, Gubina M, Hammer M, Henn BM, Hervig T, Hodoglugil U, Jha AR, Karachanak-Yankova S, Khusainova R, Khusnutdinova E, Kittles R, Kivisild T, Klitz W, Kučinskas V, Kushniarevich A, Laredj L, Litvinov S, Loukidis T, Mahley RW, Melegh B, Metspalu E, Molina J, Mountain J, Näkkäläjärvi K, Nesheva D, Nyambo T, Osipova L, Parik J, Platonov F, Posukh O, Romano V, Rothhammer F, Rudan I, Ruizbakiev R, Sahakyan H, Sajantila A, Salas A, Starikovskaya EB, Tarekegn A, Toncheva D, Turdikulova S, Uktveryte I, Utevska O, Vasquez R, Villena M, Voevoda M, Winkler CA, Yepiskoposyan L, Zalloua P, Zemunik T, Cooper A, Capelli C, Thomas MG, Ruiz-Linares A, Tishkoff SA, Singh L, Thangaraj K, Villems R, Comas D, Sukernik R, Metspalu M, Meyer M, Eichler EE, Burger J, Slatkin M, Pääbo S, Kelso J, Reich D, Krause J.

Nature. 2014 Sep 18;513(7518):409-13. doi: 10.1038/nature13673.

41.

Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.

Zanotti-Fregonara P, Zhang Y, Jenko KJ, Gladding RL, Zoghbi SS, Fujita M, Sbardella G, Castellano S, Taliani S, Martini C, Innis RB, Da Settimo F, Pike VW.

ACS Chem Neurosci. 2014 Oct 15;5(10):963-71. doi: 10.1021/cn500138n. Epub 2014 Aug 25.

42.

Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials.

Grosso G, Pajak A, Marventano S, Castellano S, Galvano F, Bucolo C, Drago F, Caraci F.

PLoS One. 2014 May 7;9(5):e96905. doi: 10.1371/journal.pone.0096905. eCollection 2014.

43.

Patterns of coding variation in the complete exomes of three Neandertals.

Castellano S, Parra G, Sánchez-Quinto FA, Racimo F, Kuhlwilm M, Kircher M, Sawyer S, Fu Q, Heinze A, Nickel B, Dabney J, Siebauer M, White L, Burbano HA, Renaud G, Stenzel U, Lalueza-Fox C, de la Rasilla M, Rosas A, Rudan P, Brajković D, Kucan Ž, Gušic I, Shunkov MV, Derevianko AP, Viola B, Meyer M, Kelso J, Andrés AM, Pääbo S.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6666-71. doi: 10.1073/pnas.1405138111. Epub 2014 Apr 21.

44.

An international age- and gender-controlled model for the Spinal Cord Injury Ability Realization Measurement Index (SCI-ARMI).

Scivoletto G, Glass C, Anderson KD, Galili T, Benjamin Y, Front L, Aidinoff E, Bluvshtein V, Itzkovich M, Aito S, Baroncini I, Benito-Penalva J, Castellano S, Osman A, Silva P, Catz A.

Neurorehabil Neural Repair. 2015 Jan;29(1):25-32. doi: 10.1177/1545968314524631. Epub 2014 Feb 28.

PMID:
24585943
45.

Structure-activity relationship refinement and further assessment of 4-phenylquinazoline-2-carboxamide translocator protein ligands as antiproliferative agents in human glioblastoma tumors.

Castellano S, Taliani S, Viviano M, Milite C, Da Pozzo E, Costa B, Barresi E, Bruno A, Cosconati S, Marinelli L, Greco G, Novellino E, Sbardella G, Da Settimo F, Martini C.

J Med Chem. 2014 Mar 27;57(6):2413-28. doi: 10.1021/jm401721h. Epub 2014 Mar 17.

PMID:
24580635
46.

Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells.

Lenoci A, Tomassi S, Conte M, Benedetti R, Rodriguez V, Carradori S, Secci D, Castellano S, Sbardella G, Filetici P, Novellino E, Altucci L, Rotili D, Mai A.

ChemMedChem. 2014 Mar;9(3):542-8. doi: 10.1002/cmdc.201300536. Epub 2014 Feb 6.

PMID:
24504685
47.

The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients.

Vecellio M, Spallotta F, Nanni S, Colussi C, Cencioni C, Derlet A, Bassetti B, Tilenni M, Carena MC, Farsetti A, Sbardella G, Castellano S, Mai A, Martelli F, Pompilio G, Capogrossi MC, Rossini A, Dimmeler S, Zeiher A, Gaetano C.

Diabetes. 2014 Jun;63(6):2132-47. doi: 10.2337/db13-0731. Epub 2014 Jan 23.

48.

Enhancement of lysine acetylation accelerates wound repair.

Spallotta F, Cencioni C, Straino S, Sbardella G, Castellano S, Capogrossi MC, Martelli F, Gaetano C.

Commun Integr Biol. 2013 Sep 1;6(5):e25466. doi: 10.4161/cib.25466. Epub 2013 Jul 2.

49.

SelenoDB 2.0: annotation of selenoprotein genes in animals and their genetic diversity in humans.

Romagné F, Santesmasses D, White L, Sarangi GK, Mariotti M, Hübler R, Weihmann A, Parra G, Gladyshev VN, Guigó R, Castellano S.

Nucleic Acids Res. 2014 Jan;42(Database issue):D437-43. doi: 10.1093/nar/gkt1045. Epub 2013 Nov 4.

50.

Effects of azole treatments on the physical properties of Candida albicans plasma membrane: a spin probe EPR study.

Sgherri C, Porta A, Castellano S, Pinzino C, Quartacci MF, Calucci L.

Biochim Biophys Acta. 2014 Jan;1838(1 Pt B):465-73. doi: 10.1016/j.bbamem.2013.10.015. Epub 2013 Oct 31.

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