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Items: 1 to 50 of 52

1.
2.

Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applications.

Aguirre R, Echeverry-Rendón M, Quintero D, Castaño JG, Harmsen MC, Robledo S, Echeverría E F.

J Biomed Mater Res A. 2018 May;106(5):1341-1354. doi: 10.1002/jbm.a.36331. Epub 2018 Jan 31.

PMID:
29316200
3.

Lysine-Less Variants of Spinal Muscular Atrophy SMN and SMNΔ7 Proteins Are Degraded by the Proteasome Pathway.

Sánchez-Lanzas R, Castaño JG.

Int J Mol Sci. 2017 Dec 8;18(12). pii: E2667. doi: 10.3390/ijms18122667.

4.

CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson's disease.

Morales-Garcia JA, Gine E, Hernandez-Encinas E, Aguilar-Morante D, Sierra-Magro A, Sanz-SanCristobal M, Alonso-Gil S, Sanchez-Lanzas R, Castaño JG, Santos A, Perez-Castillo A.

Sci Rep. 2017 Oct 19;7(1):13526. doi: 10.1038/s41598-017-13269-4.

5.

Modification of titanium alloys surface properties by plasma electrolytic oxidation (PEO) and influence on biological response.

Echeverry-Rendón M, Galvis O, Aguirre R, Robledo S, Castaño JG, Echeverría F.

J Mater Sci Mater Med. 2017 Sep 27;28(11):169. doi: 10.1007/s10856-017-5972-x.

PMID:
28956201
6.

Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease.

Sánchez-Lanzas R, Alvarez-Castelao B, Bermejo T, Ayuso T, Tuñón T, Castaño JG.

Biochim Biophys Acta. 2016 Aug;1862(8):1423-32. doi: 10.1016/j.bbadis.2016.04.014. Epub 2016 Apr 26.

7.

α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente B, Alvarez-Castelao B, Mayo I, Sierra AB, Díaz V, Milán M, Fariñas I, Gómez-Isla T, Ferrer I, Castaño JG.

J Biol Chem. 2016 Apr 22;291(17):8986. doi: 10.1074/jbc.A116.409028. No abstract available.

8.

Osseointegration improvement by plasma electrolytic oxidation of modified titanium alloys surfaces.

Echeverry-Rendón M, Galvis O, Quintero Giraldo D, Pavón J, López-Lacomba JL, Jiménez-Piqué E, Anglada M, Robledo SM, Castaño JG, Echeverría F.

J Mater Sci Mater Med. 2015 Feb;26(2):72. doi: 10.1007/s10856-015-5408-4. Epub 2015 Jan 29.

PMID:
25631270
9.

Proteins directly interacting with mammalian 20S proteasomal subunits and ubiquitin-independent proteasomal degradation.

Sánchez-Lanzas R, Castaño JG.

Biomolecules. 2014 Dec 19;4(4):1140-54. doi: 10.3390/biom4041140. Review.

10.

Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls.

Alvarez-Castelao B, Gorostidi A, Ruíz-Martínez J, López de Munain A, Castaño JG.

Front Aging Neurosci. 2014 Jul 15;6:169. doi: 10.3389/fnagi.2014.00169. eCollection 2014.

11.

Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines.

Alvarez-Castelao B, Goethals M, Vandekerckhove J, Castaño JG.

Biochim Biophys Acta. 2014 Feb;1843(2):352-65. doi: 10.1016/j.bbamcr.2013.11.018. Epub 2013 Dec 3.

12.

The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.

Alvarez-Castelao B, Losada F, Ahicart P, Castaño JG.

PLoS One. 2013;8(2):e55999. doi: 10.1371/journal.pone.0055999. Epub 2013 Feb 7.

13.

A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis.

Alvarez-Castelao B, Ruiz-Rivas C, Castaño JG.

Biochem Res Int. 2012;2012:823597. doi: 10.1155/2012/823597. Epub 2012 Oct 21.

14.

Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.

Alvarez-Castelao B, Muñoz C, Sánchez I, Goethals M, Vandekerckhove J, Castaño JG.

Biochim Biophys Acta. 2012 Feb;1823(2):524-33. doi: 10.1016/j.bbamcr.2011.11.010. Epub 2011 Dec 8.

15.

Synphilin-1 inhibits alpha-synuclein degradation by the proteasome.

Alvarez-Castelao B, Castaño JG.

Cell Mol Life Sci. 2011 Aug;68(15):2643-54. doi: 10.1007/s00018-010-0592-3. Epub 2010 Nov 20.

PMID:
21103907
16.

Cytomegalovirus promoter up-regulation is the major cause of increased protein levels of unstable reporter proteins after treatment of living cells with proteasome inhibitors.

Alvarez-Castelao B, Martín-Guerrero I, García-Orad A, Castaño JG.

J Biol Chem. 2009 Oct 9;284(41):28253-62. doi: 10.1074/jbc.M109.004101. Epub 2009 Aug 13. Retraction in: J Biol Chem. 2016 Apr 22;291(17):8985.

17.

Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis.

Casarejos MJ, Solano RM, Rodriguez-Navarro JA, Gómez A, Perucho J, Castaño JG, García de Yébenes J, Mena MA.

J Neurochem. 2009 Sep;110(5):1523-37. doi: 10.1111/j.1471-4159.2009.06248.x. Epub 2009 Jun 22.

18.

Infection with Salmonella typhimurium has no effect on the composition and cleavage specificity of the 20S proteasome in human lymphoid cells.

Marcilla M, de Castro JA, Castaño JG, Alvarez I.

Immunology. 2007 Sep;122(1):131-9. Epub 2007 May 9.

19.
20.

Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.

Díaz-Hernández M, Valera AG, Morán MA, Gómez-Ramos P, Alvarez-Castelao B, Castaño JG, Hernández F, Lucas JJ.

J Neurochem. 2006 Sep;98(5):1585-96. Epub 2006 Jun 19.

21.

Mechanism of direct degradation of IkappaBalpha by 20S proteasome.

Alvarez-Castelao B, Castaño JG.

FEBS Lett. 2005 Aug 29;579(21):4797-802.

22.

Generation of DNA double-strand breaks by two independent enzymatic activities in nuclear extracts.

Blanco MG, Boán F, Barros P, Castaño JG, Gómez-Márquez J.

J Mol Biol. 2005 Sep 2;351(5):995-1006.

PMID:
16051267
23.

alpha-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente B, Alvarez-Castelao B, Mayo I, Sierra AB, Dìaz V, Milán M, Fariñas I, Gómez-Isla T, Ferrer I, Castaño JG.

J Biol Chem. 2004 Dec 17;279(51):52984-90. Epub 2004 Oct 4. Erratum in: J Biol Chem. 2016 Apr 22;291(17):8986.

24.

Proteasomal expression, induction of immunoproteasome subunits, and local MHC class I presentation in myofibrillar myopathy and inclusion body myositis.

Ferrer I, Martín B, Castaño JG, Lucas JJ, Moreno D, Olivé M.

J Neuropathol Exp Neurol. 2004 May;63(5):484-98.

PMID:
15198127
25.

Neuronal induction of the immunoproteasome in Huntington's disease.

Díaz-Hernández M, Hernández F, Martín-Aparicio E, Gómez-Ramos P, Morán MA, Castaño JG, Ferrer I, Avila J, Lucas JJ.

J Neurosci. 2003 Dec 17;23(37):11653-61.

26.

The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity.

Gándara ML, López P, Hernando R, Castaño JG, Alemany S.

Mol Cell Biol. 2003 Oct;23(20):7377-90.

27.

The proteasome is a major autoantigen in multiple sclerosis.

Mayo I, Arribas J, Villoslada P, Alvarez DoForno R, Rodríguez-Vilariño S, Montalban X, De Sagarra MR, Castaño JG.

Brain. 2002 Dec;125(Pt 12):2658-67.

PMID:
12429593
28.

Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.

Lafarga M, Berciano MT, Pena E, Mayo I, Castaño JG, Bohmann D, Rodrigues JP, Tavanez JP, Carmo-Fonseca M.

Mol Biol Cell. 2002 Aug;13(8):2771-82.

29.

Proteasome dynamics during cell cycle in rat Schwann cells.

Lafarga M, Fernández R, Mayo I, Berciano MT, Castaño JG.

Glia. 2002 Jun;38(4):313-28.

PMID:
12007144
30.

Antibodies against the COOH-terminal region of E. coli ClpP protease in patients with primary biliary cirrhosis.

Mayo I, Arizti P, Parés A, Oliva J, Doforno RA, de Sagarra MR, Rodés J, Castaño JG.

J Hepatol. 2000 Oct;33(4):528-36.

PMID:
11059856
31.

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

Kegel KB, Kim M, Sapp E, McIntyre C, Castaño JG, Aronin N, DiFiglia M.

J Neurosci. 2000 Oct 1;20(19):7268-78.

32.

Proteolytic processing and assembly of the C5 subunit into the proteasome complex.

Rodriguez-Vilariño S, Arribas J, Arizti P, Castaño JG.

J Biol Chem. 2000 Mar 3;275(9):6592-9.

33.

Degradation of the G protein-coupled receptor kinase 2 by the proteasome pathway.

Penela P, Ruiz-Gómez A, Castaño JG, Mayor F Jr.

J Biol Chem. 1998 Dec 25;273(52):35238-44.

34.

Immunohistochemical distribution and electron microscopic subcellular localization of the proteasome in the rat CNS.

Mengual E, Arizti P, Rodrigo J, Giménez-Amaya JM, Castaño JG.

J Neurosci. 1996 Oct 15;16(20):6331-41.

35.
36.
37.

Kinetic mechanism of activation by cardiolipin (diphosphatidylglycerol) of the rat liver multicatalytic proteinase.

Ruiz de Mena I, Mahillo E, Arribas J, Castaño JG.

Biochem J. 1993 Nov 15;296 ( Pt 1):93-7.

39.

Modulation of the multicatalytic proteinase complex by lipids, interconversion and proteolytic processing.

Arizti P, Arribas J, Castaño JG.

Enzyme Protein. 1993;47(4-6):285-95.

PMID:
7697126
40.

Insulin-like effects of inositol phosphate-glycan on messenger RNA expression in rat hepatocytes.

Alvarez L, Avila MA, Mato JM, Castaño JG, Varela-Nieto I.

Mol Endocrinol. 1991 Aug;5(8):1062-8.

PMID:
1719385
41.

Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus.

Arribas J, Luz Rodríguez M, Alvarez-Do Forno R, Castaño JG.

J Exp Med. 1991 Feb 1;173(2):423-7.

42.

Regulation of gene expression by insulin.

Castaño JG.

Adv Enzyme Regul. 1991;31:185-94. Review.

PMID:
1877387
44.

Regulation of protein disulfide isomerase gene expression in brain and liver during rat development.

Mira E, Castaño JG.

Biochem Biophys Res Commun. 1990 Jul 31;170(2):421-5.

PMID:
2383249
45.
46.

Insulin short-term control of rat liver alpha 2-microglobulin gene transcription.

Mira E, Castaño JG.

J Biol Chem. 1989 Oct 25;264(30):18209-12.

47.

Eukaryotic pre-tRNA 5' processing nuclease: copurification with a complex cylindrical particle.

Castaño JG, Ornberg R, Koster JG, Tobian JA, Zasloff M.

Cell. 1986 Aug 1;46(3):377-85.

PMID:
3637121
49.

Activation of phospholipid methyltransferase by glucagon in rat hepatocytes.

Castaño JG, Alemany S, Nieto A, Mato JM.

J Biol Chem. 1980 Oct 10;255(19):9041-3.

50.

Calmodulin modulates phospholipid methylation in Dictyostelium discoideum.

Gil MG, Alemany S, Cao DM, Castano JG, Mato JM.

Biochem Biophys Res Commun. 1980 Jun 30;94(4):1325-30. No abstract available.

PMID:
6772186

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