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Items: 12

1.

Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody-Drug Conjugates.

Zhang D, Fourie-O'Donohue A, Dragovich PS, Pillow TH, Sadowsky JD, Kozak KR, Cass RT, Liu L, Deng Y, Liu Y, Hop CECA, Khojasteh SC.

Drug Metab Dispos. 2019 Oct;47(10):1156-1163. doi: 10.1124/dmd.118.086132. Epub 2019 May 13.

PMID:
31085544
2.

Plazomicin is effective in a non-human primate pneumonic plague model.

Mega WM, Doyle-Eisele M, Cass RT, Kostrub CF, Sherwood RL, Metz MA, Cirz RT.

Bioorg Med Chem. 2016 Dec 15;24(24):6429-6439. doi: 10.1016/j.bmc.2016.08.049. Epub 2016 Aug 27.

3.

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat.

Fan PW, Chen JZ, Allan Jaochico M, La H, Liu N, Mulder T, Cass RT, Durk M, Messick K, Valle N, Liu S, Lee W, Crawford JJ, Rudolf J, Murray LJ, Cyrus Khojasteh S, Wright M.

Drug Metab Lett. 2016;10(2):91-100.

4.

Pharmacokinetics and safety of single and multiple doses of ACHN-490 injection administered intravenously in healthy subjects.

Cass RT, Brooks CD, Havrilla NA, Tack KJ, Borin MT, Young D, Bruss JB.

Antimicrob Agents Chemother. 2011 Dec;55(12):5874-80. doi: 10.1128/AAC.00624-11. Epub 2011 Sep 12.

5.

Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus.

Higgins DL, Chang R, Debabov DV, Leung J, Wu T, Krause KM, Sandvik E, Hubbard JM, Kaniga K, Schmidt DE Jr, Gao Q, Cass RT, Karr DE, Benton BM, Humphrey PP.

Antimicrob Agents Chemother. 2005 Mar;49(3):1127-34.

6.

Increasing the efficiency of pharmacokinetic sample procurement, preparation and analysis by liquid chromatography/tandem mass spectrometry.

Villa JS, Cass RT, Karr DE, Adams SM, Shaw JP, Schmidt DE Jr.

Rapid Commun Mass Spectrom. 2004;18(10):1066-72.

PMID:
15150829
9.

Homodimerization of erythropoietin receptor by a bivalent monoclonal antibody triggers cell proliferation and differentiation of erythroid precursors.

Schneider H, Chaovapong W, Matthews DJ, Karkaria C, Cass RT, Zhan H, Boyle M, Lorenzini T, Elliott SG, Giebel LB.

Blood. 1997 Jan 15;89(2):473-82.

PMID:
9002949
10.

A sequential dimerization mechanism for erythropoietin receptor activation.

Matthews DJ, Topping RS, Cass RT, Giebel LB.

Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9471-6.

11.

Topochemical catalysis achieved by structure-based ligand design.

Katz BA, Cass RT, Liu B, Arze R, Collins N.

J Biol Chem. 1995 Dec 29;270(52):31210-8.

12.

Screening of cyclic peptide phage libraries identifies ligands that bind streptavidin with high affinities.

Giebel LB, Cass RT, Milligan DL, Young DC, Arze R, Johnson CR.

Biochemistry. 1995 Nov 28;34(47):15430-5.

PMID:
7492543

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