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Items: 1 to 50 of 85

1.

Natural moisturizing factor as a clinical marker in atopic dermatitis.

Nouwen AEM, Karadavut D, Pasmans SGMA, Elbert NJ, Bos LDN, Nijsten TEC, Arends NJT, Pijnenburg MWH, Koljenović S, Puppels GJ, Caspers PJ.

Allergy. 2019 Jun 10. doi: 10.1111/all.13942. [Epub ahead of print] No abstract available.

PMID:
31179552
2.

Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic.

Scaiola A, Leibundgut M, Boehringer D, Caspers P, Bur D, Locher HH, Rueedi G, Ritz D.

Sci Rep. 2019 Apr 4;9(1):5634. doi: 10.1038/s41598-019-42155-4.

3.

Reply to Comment on "Improving clinical diagnosis of early-stage cutaneous melanoma based on Raman spectroscopy".

Santos IP, Caspers PJ, van Doorn R, Koljenović S, Puppels GJ.

Br J Cancer. 2019 Apr;120(8):865-866. doi: 10.1038/s41416-019-0431-8. Epub 2019 Mar 22. No abstract available.

PMID:
30899089
4.

Improving clinical diagnosis of early-stage cutaneous melanoma based on Raman spectroscopy.

P Santos I, van Doorn R, Caspers PJ, Bakker Schut TC, Barroso EM, Nijsten TEC, Noordhoek Hegt V, Koljenović S, Puppels GJ.

Br J Cancer. 2018 Nov;119(11):1339-1346. doi: 10.1038/s41416-018-0257-9. Epub 2018 Nov 9.

PMID:
30410059
5.

Raman spectroscopic analysis of the molecular composition of oral cavity squamous cell carcinoma and healthy tongue tissue.

Cals FLJ, Bakker Schut TC, Caspers PJ, Baatenburg de Jong RJ, Koljenović S, Puppels GJ.

Analyst. 2018 Aug 20;143(17):4090-4102. doi: 10.1039/c7an02106b.

PMID:
30083685
6.

Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A.

Hattori H, Roesslein J, Caspers P, Zerbe K, Miyatake-Ondozabal H, Ritz D, Rueedi G, Gademann K.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):11020-11024. doi: 10.1002/anie.201805770. Epub 2018 Jul 18.

PMID:
29943519
7.

A design for a dynamic biomimetic sonarhead inspired by horseshoe bats.

Caspers P, Müller R.

Bioinspir Biomim. 2018 Jun 26;13(4):046011. doi: 10.1088/1748-3190/aac788.

PMID:
29794330
8.

Potential of short-wave infrared spectroscopy for quantitative depth profiling of stratum corneum lipids and water in dermatology.

Ezerskaia A, Uzunbajakava NE, Puppels GJ, de Sterke J, Caspers PJ, Urbach HP, Varghese B.

Biomed Opt Express. 2018 Apr 27;9(5):2436-2450. doi: 10.1364/BOE.9.002436. eCollection 2018 May 1.

9.

A Unified Analysis of Structured Sonar-terrain Data using Bayesian Functional Mixed Models.

Zhu H, Caspers P, Morris JS, Wu X, Müller R.

Technometrics. 2018;60(1):112-123. doi: 10.1080/00401706.2016.1274681. Epub 2017 May 25.

10.

Raman spectroscopy for assessment of bone resection margins in mandibulectomy for oral cavity squamous cell carcinoma.

Barroso EM, Ten Hove I, Bakker Schut TC, Mast H, van Lanschot CGF, Smits RWH, Caspers PJ, Verdijk R, Noordhoek Hegt V, Baatenburg de Jong RJ, Wolvius EB, Puppels GJ, Koljenović S.

Eur J Cancer. 2018 Mar;92:77-87. doi: 10.1016/j.ejca.2018.01.068. Epub 2018 Feb 8.

PMID:
29428867
11.

Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery.

Boitor R, Kong K, Shipp D, Varma S, Koloydenko A, Kulkarni K, Elsheikh S, Schut TB, Caspers P, Puppels G, van der Wolf M, Sokolova E, Nijsten TEC, Salence B, Williams H, Notingher I.

Biomed Opt Express. 2017 Nov 22;8(12):5749-5766. doi: 10.1364/BOE.8.005749. eCollection 2017 Dec 1.

12.

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics.

Santos IP, Barroso EM, Bakker Schut TC, Caspers PJ, van Lanschot CGF, Choi DH, van der Kamp MF, Smits RWH, van Doorn R, Verdijk RM, Noordhoek Hegt V, von der Thüsen JH, van Deurzen CHM, Koppert LB, van Leenders GJLH, Ewing-Graham PC, van Doorn HC, Dirven CMF, Busstra MB, Hardillo J, Sewnaik A, Ten Hove I, Mast H, Monserez DA, Meeuwis C, Nijsten T, Wolvius EB, Baatenburg de Jong RJ, Puppels GJ, Koljenović S.

Analyst. 2017 Aug 21;142(17):3025-3047. doi: 10.1039/c7an00957g. Review.

PMID:
28726868
13.

Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis.

Caspers P, Locher HH, Pfaff P, Diggelmann S, Rueedi G, Bur D, Ritz D.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00384-17. doi: 10.1128/AAC.00384-17. Print 2017 Aug.

14.

Dynamic Substrate for the Physical Encoding of Sensory Information in Bat Biosonar.

Müller R, Gupta AK, Zhu H, Pannala M, Gillani US, Fu Y, Caspers P, Buck JR.

Phys Rev Lett. 2017 Apr 14;118(15):158102. doi: 10.1103/PhysRevLett.118.158102. Epub 2017 Apr 11.

PMID:
28452520
15.

Sensitive Skin: Assessment of the Skin Barrier Using Confocal Raman Microspectroscopy.

Richters RJ, Falcone D, Uzunbajakava NE, Varghese B, Caspers PJ, Puppels GJ, van Erp PE, van de Kerkhof PC.

Skin Pharmacol Physiol. 2017;30(1):1-12. doi: 10.1159/000452152. Epub 2017 Jan 26.

16.

A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents.

Azan A, Caspers PJ, Bakker Schut TC, Roy S, Boutros C, Mateus C, Routier E, Besse B, Planchard D, Seck A, Kamsu Kom N, Tomasic G, Koljenović S, Noordhoek Hegt V, Texier M, Lanoy E, Eggermont AM, Paci A, Robert C, Puppels GJ, Mir LM.

Cancer Res. 2017 Jan 15;77(2):557-565. doi: 10.1158/0008-5472.CAN-16-1733. Epub 2016 Nov 11.

17.

Determination of natural moisturizing factors in the skin: Raman microspectroscopy versus HPLC.

Koppes SA, Kemperman P, Van Tilburg I, Calkoen-Kwa F, Engebretsen KA, Puppels GJ, Caspers PJ, Kezic S.

Biomarkers. 2017 Sep;22(6):502-507. doi: 10.1080/1354750X.2016.1256428. Epub 2017 Jan 19.

PMID:
27805415
18.

Water Concentration Analysis by Raman Spectroscopy to Determine the Location of the Tumor Border in Oral Cancer Surgery.

Barroso EM, Smits RW, van Lanschot CG, Caspers PJ, Ten Hove I, Mast H, Sewnaik A, Hardillo JA, Meeuwis CA, Verdijk R, Noordhoek Hegt V, Baatenburg de Jong RJ, Wolvius EB, Bakker Schut TC, Koljenović S, Puppels GJ.

Cancer Res. 2016 Oct 15;76(20):5945-5953. Epub 2016 Aug 16.

19.

Raman Spectroscopic Characterization of Melanoma and Benign Melanocytic Lesions Suspected of Melanoma Using High-Wavenumber Raman Spectroscopy.

Santos IP, Caspers PJ, Bakker Schut TC, van Doorn R, Noordhoek Hegt V, Koljenović S, Puppels GJ.

Anal Chem. 2016 Aug 2;88(15):7683-8. doi: 10.1021/acs.analchem.6b01592. Epub 2016 Jul 22.

PMID:
27382927
20.

A dynamic ultrasonic emitter inspired by horseshoe bat noseleaves.

Fu Y, Caspers P, Müller R.

Bioinspir Biomim. 2016 Apr 29;11(3):036007. doi: 10.1088/1748-3190/11/3/036007.

PMID:
27127194
21.

Real-time detection of p-phenylenediamine penetration into human skin by in vivo Raman spectroscopy.

Pot LM, Coenraads PJ, Blömeke B, Puppels GJ, Caspers PJ.

Contact Dermatitis. 2016 Mar;74(3):152-8. doi: 10.1111/cod.12523. Epub 2016 Jan 18.

PMID:
26778536
22.

Water resistance profile as a marker of skin barrier damage in atopic dermatitis patients.

van Logtestijn MD, Caspers PJ, Kezic S, Hoffman DR, Koenig DW, Ono M, Stamatas GN, Tanaka RJ.

J Dermatol Sci. 2016 Feb;81(2):126-8. doi: 10.1016/j.jdermsci.2015.10.017. Epub 2015 Nov 14. No abstract available.

23.

Eigenbeam analysis of the diversity in bat biosonar beampatterns.

Caspers P, Müller R.

J Acoust Soc Am. 2015 Mar;137(3):1081-7. doi: 10.1121/1.4908562.

PMID:
25786923
24.

Lipid to protein ratio plays an important role in the skin barrier function in patients with atopic eczema.

Janssens M, van Smeden J, Puppels GJ, Lavrijsen AP, Caspers PJ, Bouwstra JA.

Br J Dermatol. 2014 Jun;170(6):1248-55. doi: 10.1111/bjd.12908.

PMID:
24641443
25.

The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients.

van Smeden J, Janssens M, Kaye EC, Caspers PJ, Lavrijsen AP, Vreeken RJ, Bouwstra JA.

Exp Dermatol. 2014 Jan;23(1):45-52. doi: 10.1111/exd.12293.

PMID:
24299153
26.

Investigations of the mode of action and resistance development of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.

Locher HH, Caspers P, Bruyère T, Schroeder S, Pfaff P, Knezevic A, Keck W, Ritz D.

Antimicrob Agents Chemother. 2014;58(2):901-8. doi: 10.1128/AAC.01831-13. Epub 2013 Nov 25.

27.

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients.

Janssens M, van Smeden J, Gooris GS, Bras W, Portale G, Caspers PJ, Vreeken RJ, Hankemeier T, Kezic S, Wolterbeek R, Lavrijsen AP, Bouwstra JA.

J Lipid Res. 2012 Dec;53(12):2755-66. doi: 10.1194/jlr.P030338. Epub 2012 Sep 28.

28.

A new in vivo Raman probe for enhanced applicability to the body.

Pudney PD, Bonnist EY, Caspers PJ, Gorce JP, Marriot C, Puppels GJ, Singleton S, van der Wolf MJ.

Appl Spectrosc. 2012 Aug;66(8):882-91. doi: 10.1366/12-06640. Epub 2012 Jul 13.

PMID:
22800645
29.

Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD.

J Allergy Clin Immunol. 2012 Apr;129(4):1031-9.e1. doi: 10.1016/j.jaci.2011.12.989. Epub 2012 Feb 8.

30.

Raman spectroscopy with an integrated arrayed-waveguide grating.

Ismail N, Choo-Smith LP, Wörhoff K, Driessen A, Baclig AC, Caspers PJ, Puppels GJ, de Ridder RM, Pollnau M.

Opt Lett. 2011 Dec 1;36(23):4629-31. doi: 10.1364/OL.36.004629.

PMID:
22139265
31.

Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema.

Janssens M, van Smeden J, Gooris GS, Bras W, Portale G, Caspers PJ, Vreeken RJ, Kezic S, Lavrijsen AP, Bouwstra JA.

J Invest Dermatol. 2011 Oct;131(10):2136-8. doi: 10.1038/jid.2011.175. Epub 2011 Jun 30. No abstract available.

32.

Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin.

Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W.

J Invest Dermatol. 2011 Nov;131(11):2233-41. doi: 10.1038/jid.2011.153. Epub 2011 Jun 9.

33.

Kinetics of carotenoid distribution in human skin in vivo after exogenous stress: disinfectant and wIRA-induced carotenoid depletion recovers from outside to inside.

Fluhr JW, Caspers P, van der Pol JA, Richter H, Sterry W, Lademann J, Darvin ME.

J Biomed Opt. 2011 Mar;16(3):035002. doi: 10.1117/1.3555183.

34.

Asparaginyl-tRNA synthetase pre-transfer editing assay.

Danel F, Caspers P, Nuoffer C, Härtlein M, Kron MA, Page MG.

Curr Drug Discov Technol. 2011 Mar;8(1):66-75.

PMID:
21091430
35.

Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes.

O'Regan GM, Kemperman PM, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WH, Caspers PJ, Irvine AD.

J Allergy Clin Immunol. 2010 Sep;126(3):574-80.e1. doi: 10.1016/j.jaci.2010.04.038.

36.

Propenylamide and propenylsulfonamide cephalosporins as a novel class of anti-MRSA beta-lactams.

Pohlmann J, Vasilevich NI, Glushkov AI, Kellenberger L, Shapiro S, Caspers P, Page MG, Danel F.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4635-8. doi: 10.1016/j.bmcl.2010.05.110. Epub 2010 Jun 8.

PMID:
20576430
37.

In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria.

Bowker KE, Caspers P, Gaucher B, MacGowan AP.

Antimicrob Agents Chemother. 2009 Nov;53(11):4949-52. doi: 10.1128/AAC.00845-09. Epub 2009 Sep 8.

38.

In vivo distribution of carotenoids in different anatomical locations of human skin: comparative assessment with two different Raman spectroscopy methods.

Darvin ME, Fluhr JW, Caspers P, van der Pool A, Richter H, Patzelt A, Sterry W, Lademann J.

Exp Dermatol. 2009 Dec;18(12):1060-3. doi: 10.1111/j.1600-0625.2009.00946.x.

PMID:
19650865
39.

In vitro and in vivo properties of dihydrophthalazine antifolates, a novel family of antibacterial drugs.

Caspers P, Bury L, Gaucher B, Heim J, Shapiro S, Siegrist S, Schmitt-Hoffmann A, Thenoz L, Urwyler H.

Antimicrob Agents Chemother. 2009 Sep;53(9):3620-7. doi: 10.1128/AAC.00377-09. Epub 2009 Jun 22.

40.

Depth profiling of Stratum corneum hydration in vivo: a comparison between conductance and confocal Raman spectroscopic measurements.

Boncheva M, de Sterke J, Caspers PJ, Puppels GJ.

Exp Dermatol. 2009 Oct;18(10):870-6. doi: 10.1111/j.1600-0625.2009.00868.x. Epub 2009 Mar 10.

PMID:
19469890
41.

Studying the effectiveness of penetration enhancers to deliver retinol through the stratum cornum by in vivo confocal Raman spectroscopy.

Mélot M, Pudney PD, Williamson AM, Caspers PJ, Van Der Pol A, Puppels GJ.

J Control Release. 2009 Aug 19;138(1):32-9. doi: 10.1016/j.jconrel.2009.04.023. Epub 2009 May 4.

PMID:
19401210
42.

Towards oncological application of Raman spectroscopy.

Nijssen A, Koljenović S, Bakker Schut TC, Caspers PJ, Puppels GJ.

J Biophotonics. 2009 Feb;2(1-2):29-36. doi: 10.1002/jbio.200810055. Review.

PMID:
19343683
43.

Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.

Clark C, Ednie LM, Lin G, Smith K, Kosowska-Shick K, McGhee P, Dewasse B, Beachel L, Caspers P, Gaucher B, Mert G, Shapiro S, Appelbaum PC.

Antimicrob Agents Chemother. 2009 Apr;53(4):1353-61. doi: 10.1128/AAC.01619-08. Epub 2009 Feb 2.

44.

Frequency of ill-founded off-label prescribing in Dutch general practice.

Gijsen R, Jochemsen H, van Dijk L, Caspers P.

Pharmacoepidemiol Drug Saf. 2009 Jan;18(1):84-91. doi: 10.1002/pds.1689.

PMID:
19111012
45.

Loss-of-function mutations in the filaggrin gene lead to reduced level of natural moisturizing factor in the stratum corneum.

Kezic S, Kemperman PM, Koster ES, de Jongh CM, Thio HB, Campbell LE, Irvine AD, McLean WH, Puppels GJ, Caspers PJ.

J Invest Dermatol. 2008 Aug;128(8):2117-9. doi: 10.1038/jid.2008.29. Epub 2008 Feb 28. No abstract available. Erratum in: J Invest Dermatol. 2008 Jun;128(6):1604. McLean, Irwin W H [corrected to McLean, W H Irwin].

46.

An in vivo confocal Raman study of the delivery of trans retinol to the skin.

Pudney PD, Mélot M, Caspers PJ, Van Der Pol A, Puppels GJ.

Appl Spectrosc. 2007 Aug;61(8):804-11.

PMID:
17716398
47.

Discriminating basal cell carcinoma from perilesional skin using high wave-number Raman spectroscopy.

Nijssen A, Maquelin K, Santos LF, Caspers PJ, Bakker Schut TC, den Hollander JC, Neumann MH, Puppels GJ.

J Biomed Opt. 2007 May-Jun;12(3):034004.

48.

Assessment of the "skin reservoir" of urea by confocal Raman microspectroscopy and reverse iontophoresis in vivo.

Wascotte V, Caspers P, de Sterke J, Jadoul M, Guy RH, Préat V.

Pharm Res. 2007 Oct;24(10):1897-901. Epub 2007 May 12.

PMID:
17497081
49.

Determinants of potential drug-drug interaction associated dispensing in community pharmacies in the Netherlands.

Becker ML, Caspers PW, Kallewaard M, Bruinink RJ, Kylstra NB, Heisterkamp S, de Valk V, van der Veen AA, Stricker BH.

Pharm World Sci. 2007 Apr;29(2):51-7. Epub 2006 Dec 23.

50.

Hospitalisations and emergency department visits due to drug-drug interactions: a literature review.

Becker ML, Kallewaard M, Caspers PW, Visser LE, Leufkens HG, Stricker BH.

Pharmacoepidemiol Drug Saf. 2007 Jun;16(6):641-51. Review.

PMID:
17154346

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