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Items: 1 to 50 of 51

1.

The B-cell receptor in control of tumor B-cell fitness: Biology and clinical relevance.

Casola S, Perucho L, Tripodo C, Sindaco P, Ponzoni M, Facchetti F.

Immunol Rev. 2019 Mar;288(1):198-213. doi: 10.1111/imr.12738. Review.

PMID:
30874349
2.

Impact of systemic and tumor lipid metabolism on everolimus efficacy in advanced pancreatic neuroendocrine tumors (pNETs).

Vernieri C, Pusceddu S, Fucà G, Indelicato P, Centonze G, Castagnoli L, Ferrari E, Ajazi A, Pupa S, Casola S, Foiani M, Mazzaferro V, Pruneri G, Milione M, de Braud F.

Int J Cancer. 2019 Apr 1;144(7):1704-1712. doi: 10.1002/ijc.32042. Epub 2019 Jan 7.

PMID:
30520016
3.

Individuals with FANCM biallelic mutations do not develop Fanconi anemia, but show risk for breast cancer, chemotherapy toxicity and may display chromosome fragility.

Catucci I, Osorio A, Arver B, Neidhardt G, Bogliolo M, Zanardi F, Riboni M, Minardi S, Pujol R, Azzollini J, Peissel B, Manoukian S, De Vecchi G, Casola S, Hauke J, Richters L, Rhiem K, Schmutzler RK, Wallander K, Törngren T, Borg Å, Radice P, Surrallés J, Hahnen E, Ehrencrona H, Kvist A, Benitez J, Peterlongo P.

Genet Med. 2018 Apr;20(4):452-457. doi: 10.1038/gim.2017.123. Epub 2017 Aug 24.

PMID:
28837162
4.

Targeting Gene Function in Germinal Center B Cells: A Practical Approach.

Petrocelli V, Casola S.

Methods Mol Biol. 2017;1623:209-231. doi: 10.1007/978-1-4939-7095-7_17.

PMID:
28589359
5.

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.

Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M, Facchetti F, Rajewsky K, Casola S.

Nature. 2017 Jun 8;546(7657):302-306. doi: 10.1038/nature22353. Epub 2017 May 31.

PMID:
28562582
6.

EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.

Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, Reißig S, Lacher SM, Reichhold C, Mufazalov IA, Ben-Nun A, Kuhlmann T, Wettschureck N, Sailer AW, Rajewsky K, Casola S, Waisman A, Kurschus FC.

Cell Rep. 2017 Jan 31;18(5):1270-1284. doi: 10.1016/j.celrep.2017.01.020.

7.

Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions.

Vernieri C, Casola S, Foiani M, Pietrantonio F, de Braud F, Longo V.

Cancer Discov. 2016 Dec;6(12):1315-1333. Epub 2016 Nov 21. Review.

8.

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth.

Mihailovich M, Bremang M, Spadotto V, Musiani D, Vitale E, Varano G, Zambelli F, Mancuso FM, Cairns DA, Pavesi G, Casola S, Bonaldi T.

Nat Commun. 2015 Nov 10;6:8725. doi: 10.1038/ncomms9725.

9.

Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell.

Kumar R, Bach MP, Mainoldi F, Maruya M, Kishigami S, Jumaa H, Wakayama T, Kanagawa O, Fagarasan S, Casola S.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E450-7. doi: 10.1073/pnas.1417988112. Epub 2015 Jan 21.

10.

An epigenetic view of B-cell disorders.

Alberghini F, Petrocelli V, Rahmat M, Casola S.

Immunol Cell Biol. 2015 Mar;93(3):253-60. doi: 10.1038/icb.2014.116. Epub 2015 Jan 20. Review.

PMID:
25601271
11.

SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.

Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P.

Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23.

12.

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.

Piunti A, Rossi A, Cerutti A, Albert M, Jammula S, Scelfo A, Cedrone L, Fragola G, Olsson L, Koseki H, Testa G, Casola S, Helin K, d'Adda di Fagagna F, Pasini D.

Nat Commun. 2014 Apr 14;5:3649. doi: 10.1038/ncomms4649.

13.

Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity.

Colombo E, Tentorio P, Musio S, Rajewsky K, Pedotti R, Casola S, Farina C.

Clin Exp Immunol. 2014 Apr;176(1):58-65. doi: 10.1111/cei.12250.

14.

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

Caganova M, Carrisi C, Varano G, Mainoldi F, Zanardi F, Germain PL, George L, Alberghini F, Ferrarini L, Talukder AK, Ponzoni M, Testa G, Nojima T, Doglioni C, Kitamura D, Toellner KM, Su IH, Casola S.

J Clin Invest. 2013 Dec;123(12):5009-22. doi: 10.1172/JCI70626. Epub 2013 Nov 8. Erratum in: J Clin Invest. 2014 Apr 1;124(4):1869.

15.

T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.

Fogli LK, Sundrud MS, Goel S, Bajwa S, Jensen K, Derudder E, Sun A, Coffre M, Uyttenhove C, Van Snick J, Schmidt-Supprian M, Rao A, Grunig G, Durbin J, Casola S, Rajewsky K, Koralov SB.

J Immunol. 2013 Sep 15;191(6):3100-11. doi: 10.4049/jimmunol.1301360. Epub 2013 Aug 21. Erratum in: J Immunol. 2013 Nov 15;191(10):5318. Casola, Stefano S [corrected to Casola, Stefano].

16.

Cell reprogramming requires silencing of a core subset of polycomb targets.

Fragola G, Germain PL, Laise P, Cuomo A, Blasimme A, Gross F, Signaroldi E, Bucci G, Sommer C, Pruneri G, Mazzarol G, Bonaldi T, Mostoslavsky G, Casola S, Testa G.

PLoS Genet. 2013;9(2):e1003292. doi: 10.1371/journal.pgen.1003292. Epub 2013 Feb 28.

17.

Plasma cells require autophagy for sustainable immunoglobulin production.

Pengo N, Scolari M, Oliva L, Milan E, Mainoldi F, Raimondi A, Fagioli C, Merlini A, Mariani E, Pasqualetto E, Orfanelli U, Ponzoni M, Sitia R, Casola S, Cenci S.

Nat Immunol. 2013 Mar;14(3):298-305. doi: 10.1038/ni.2524. Epub 2013 Jan 27.

PMID:
23354484
18.

B-cell receptor signal strength influences terminal differentiation.

Lechouane F, Bonaud A, Delpy L, Casola S, Oruc Z, Chemin G, Cogné M, Sirac C.

Eur J Immunol. 2013 Mar;43(3):619-28. doi: 10.1002/eji.201242912. Epub 2013 Jan 24.

19.

The endocytic adaptor Eps15 controls marginal zone B cell numbers.

Pozzi B, Amodio S, Lucano C, Sciullo A, Ronzoni S, Castelletti D, Adler T, Treise I, Betsholtz IH, Rathkolb B, Busch DH, Wolf E, Fuchs H, Gailus-Durner V, de Angelis MH, Betsholtz C, Casola S, Di Fiore PP, Offenhäuser N.

PLoS One. 2012;7(11):e50818. doi: 10.1371/journal.pone.0050818. Epub 2012 Nov 30.

20.

The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival.

Burgold T, Voituron N, Caganova M, Tripathi PP, Menuet C, Tusi BK, Spreafico F, Bévengut M, Gestreau C, Buontempo S, Simeone A, Kruidenier L, Natoli G, Casola S, Hilaire G, Testa G.

Cell Rep. 2012 Nov 29;2(5):1244-58. doi: 10.1016/j.celrep.2012.09.013. Epub 2012 Oct 25.

21.

Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model.

Zhang B, Kracker S, Yasuda T, Casola S, Vanneman M, Hömig-Hölzel C, Wang Z, Derudder E, Li S, Chakraborty T, Cotter SE, Koyama S, Currie T, Freeman GJ, Kutok JL, Rodig SJ, Dranoff G, Rajewsky K.

Cell. 2012 Feb 17;148(4):739-51. doi: 10.1016/j.cell.2011.12.031.

22.

The LRF transcription factor regulates mature B cell development and the germinal center response in mice.

Sakurai N, Maeda M, Lee SU, Ishikawa Y, Li M, Williams JC, Wang L, Su L, Suzuki M, Saito TI, Chiba S, Casola S, Yagita H, Teruya-Feldstein J, Tsuzuki S, Bhatia R, Maeda T.

J Clin Invest. 2011 Jul;121(7):2583-98. doi: 10.1172/JCI45682. Epub 2011 Jun 6.

23.

Genomic instability in induced stem cells.

Pasi CE, Dereli-Öz A, Negrini S, Friedli M, Fragola G, Lombardo A, Van Houwe G, Naldini L, Casola S, Testa G, Trono D, Pelicci PG, Halazonetis TD.

Cell Death Differ. 2011 May;18(5):745-53. doi: 10.1038/cdd.2011.9. Epub 2011 Feb 11.

24.

Mouse models for miRNA expression: the ROSA26 locus.

Casola S.

Methods Mol Biol. 2010;667:145-63. doi: 10.1007/978-1-60761-811-9_10.

PMID:
20827532
25.

The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining.

Grazini U, Zanardi F, Citterio E, Casola S, Goding CR, McBlane F.

Mol Cell. 2010 Jan 29;37(2):282-93. doi: 10.1016/j.molcel.2009.12.035.

26.

Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma.

Omodei D, Acampora D, Russo F, De Filippi R, Severino V, Di Francia R, Frigeri F, Mancuso P, De Chiara A, Pinto A, Casola S, Simeone A.

Am J Pathol. 2009 Dec;175(6):2609-17. doi: 10.2353/ajpath.2009.090542. Epub 2009 Nov 5.

27.

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages.

De Santa F, Narang V, Yap ZH, Tusi BK, Burgold T, Austenaa L, Bucci G, Caganova M, Notarbartolo S, Casola S, Testa G, Sung WK, Wei CL, Natoli G.

EMBO J. 2009 Nov 4;28(21):3341-52. doi: 10.1038/emboj.2009.271. Epub 2009 Sep 24.

28.

PLC-gamma2 is essential for formation and maintenance of memory B cells.

Hikida M, Casola S, Takahashi N, Kaji T, Takemori T, Rajewsky K, Kurosaki T.

J Exp Med. 2009 Mar 16;206(3):681-9. doi: 10.1084/jem.20082100. Epub 2009 Mar 9.

29.

Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis.

Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW.

Immunity. 2008 Oct 17;29(4):615-27. doi: 10.1016/j.immuni.2008.07.016. Epub 2008 Oct 2.

30.

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.

Hömig-Hölzel C, Hojer C, Rastelli J, Casola S, Strobl LJ, Müller W, Quintanilla-Martinez L, Gewies A, Ruland J, Rajewsky K, Zimber-Strobl U.

J Exp Med. 2008 Jun 9;205(6):1317-29. doi: 10.1084/jem.20080238. Epub 2008 May 19.

31.

Regulation of the germinal center response by microRNA-155.

Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K.

Science. 2007 Apr 27;316(5824):604-8.

32.

Control of peripheral B-cell development.

Casola S.

Curr Opin Immunol. 2007 Apr;19(2):143-9. Epub 2007 Feb 15. Review.

PMID:
17303401
33.

B cell recruitment and selection in mouse GALT germinal centers.

Casola S, Rajewsky K.

Curr Top Microbiol Immunol. 2006;308:155-71. Review.

PMID:
16922090
34.

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R.

Nat Immunol. 2006 Jul;7(7):773-82. Epub 2006 Jun 11.

PMID:
16767092
35.

Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting.

Casola S, Cattoretti G, Uyttersprot N, Koralov SB, Seagal J, Hao Z, Waisman A, Egert A, Ghitza D, Rajewsky K.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7396-401. Epub 2006 May 1. Erratum in: Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):2025. Segal, Jane [corrected to Seagal, Jane].

36.

Attenuated liver fibrosis in the absence of B cells.

Novobrantseva TI, Majeau GR, Amatucci A, Kogan S, Brenner I, Casola S, Shlomchik MJ, Koteliansky V, Hochman PS, Ibraghimov A.

J Clin Invest. 2005 Nov;115(11):3072-82.

37.

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M.

J Immunol. 2004 Aug 15;173(4):2245-52.

38.

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ, Rajewsky K.

J Immunol. 2004 Aug 1;173(3):1612-9.

39.

Conditional gene mutagenesis in B-lineage cells.

Casola S.

Methods Mol Biol. 2004;271:91-109.

PMID:
15146115
40.

B cell receptor signal strength determines B cell fate.

Casola S, Otipoby KL, Alimzhanov M, Humme S, Uyttersprot N, Kutok JL, Carroll MC, Rajewsky K.

Nat Immunol. 2004 Mar;5(3):317-27. Epub 2004 Feb 1.

PMID:
14758357
41.

The H19 endodermal enhancer is required for Igf2 activation and tumor formation in experimental liver carcinogenesis.

Vernucci M, Cerrato F, Besnard N, Casola S, Pedone PV, Bruni CB, Riccio A.

Oncogene. 2000 Dec 14;19(54):6376-85.

42.

Relaxation of insulin-like growth factor 2 imprinting and discordant methylation at KvDMR1 in two first cousins affected by Beckwith-Wiedemann and Klippel-Trenaunay-Weber syndromes.

Sperandeo MP, Ungaro P, Vernucci M, Pedone PV, Cerrato F, Perone L, Casola S, Cubellis MV, Bruni CB, Andria G, Sebastio G, Riccio A.

Am J Hum Genet. 2000 Mar;66(3):841-7.

43.

Relaxation of insulin-like growth factor-2 imprinting in rat cultured cells.

Ungaro P, Casola S, Vernucci M, Pedone PV, Bruni CB, Riccio A.

Mol Cell Endocrinol. 1997 Dec 12;135(2):153-63.

PMID:
9484911
44.

Expression and parental imprinting of the H19 gene in human rhabdomyosarcoma.

Casola S, Pedone PV, Cavazzana AO, Basso G, Luksch R, d'Amore ES, Carli M, Bruni CB, Riccio A.

Oncogene. 1997 Mar 27;14(12):1503-10. Erratum in: Oncogene 1997 Aug 14;15(7):875.

45.

Constitutive insulin-like growth factor-II expression interferes with the enterocyte-like differentiation of CaCo-2 cells.

Zarrilli R, Romano M, Pignata S, Casola S, Bruni CB, Acquaviva AM.

J Biol Chem. 1996 Apr 5;271(14):8108-14.

46.

Preferential loss of heterozygosity of chromosome 7 loci in simian virus 40 t/T antigen-induced mouse hepatocellular carcinomas does not involve H-ras mutations.

Casola S, Vernucci M, Ungaro P, Bruni CB, Riccio A.

Acta Genet Med Gemellol (Roma). 1996;45(1-2):221-5. No abstract available.

PMID:
8872035
47.

Loss of heterozygosity of imprinted genes in SV40 t/T antigen-induced hepatocellular carcinomas.

Casola S, Ungaro P, Pedone PV, Lazzaro D, Fattori E, Ciliberto G, Zarrilli R, Bruni CB, Riccio A.

Oncogene. 1995 Aug 17;11(4):711-21.

PMID:
7651735
48.

Expression of insulin-like growth factor (IGF)-II and IGF-I receptor during proliferation and differentiation of CaCo-2 human colon carcinoma cells.

Zarrilli R, Pignata S, Romano M, Gravina A, Casola S, Bruni CB, Acquaviva AM.

Cell Growth Differ. 1994 Oct;5(10):1085-91.

50.

Extinction of insulin-like growth factor II gene expression in intratypic hybrids of rat liver cells.

Zarrilli R, Casola S, Conti A, Bruni CB, Colantuoni V.

Mol Endocrinol. 1993 Jan;7(1):131-41.

PMID:
8446103

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