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Items: 1 to 50 of 51

1.

High Thyrotropin Is Critical for Cardiac Electrical Remodeling and Arrhythmia Vulnerability in Hypothyroidism.

Fernandez-Ruocco J, Gallego M, Rodriguez-de-Yurre A, Zayas-Arrabal J, Echeazarra L, Alquiza A, Fernández-López V, Rodriguez-Robledo JM, Brito O, Schleier Y, Sepulveda M, Oshiyama NF, Vila-Petroff M, Bassani RA, Medei EH, Casis O.

Thyroid. 2019 Jul;29(7):934-945. doi: 10.1089/thy.2018.0709. Epub 2019 Jun 13.

2.

The Crossroad of Ion Channels and Calmodulin in Disease.

Urrutia J, Aguado A, Muguruza-Montero A, Núñez E, Malo C, Casis O, Villarroel A.

Int J Mol Sci. 2019 Jan 18;20(2). pii: E400. doi: 10.3390/ijms20020400. Review.

3.

Mechanisms of IhERG/IKr Modulation by α1-Adrenoceptors in HEK293 Cells and Cardiac Myocytes.

Urrutia J, Alday A, Gallego M, Malagueta-Vieira LL, Aréchiga-Figueroa IA, Casis O, Sánchez-Chapula JA.

Cell Physiol Biochem. 2016;40(6):1261-1273. doi: 10.1159/000453180. Epub 2016 Dec 19.

4.

Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice.

Monnerat G, Alarcón ML, Vasconcellos LR, Hochman-Mendez C, Brasil G, Bassani RA, Casis O, Malan D, Travassos LH, Sepúlveda M, Burgos JI, Vila-Petroff M, Dutra FF, Bozza MT, Paiva CN, Carvalho AB, Bonomo A, Fleischmann BK, de Carvalho ACC, Medei E.

Nat Commun. 2016 Nov 24;7:13344. doi: 10.1038/ncomms13344.

5.

Thyroid stimulating hormone directly modulates cardiac electrical activity.

Alonso H, Fernández-Ruocco J, Gallego M, Malagueta-Vieira LL, Rodríguez-de-Yurre A, Medei E, Casis O.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):280-6. doi: 10.1016/j.yjmcc.2015.10.019. Epub 2015 Oct 20.

6.

Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway.

Monnerat-Cahli G, Alonso H, Gallego M, Alarcón ML, Bassani RA, Casis O, Medei E.

J Mol Cell Cardiol. 2014 Nov;76:116-25. doi: 10.1016/j.yjmcc.2014.08.012. Epub 2014 Aug 25.

PMID:
25169970
7.

Ionic channels underlying the ventricular action potential in zebrafish embryo.

Alday A, Alonso H, Gallego M, Urrutia J, Letamendia A, Callol C, Casis O.

Pharmacol Res. 2014 Jun;84:26-31. doi: 10.1016/j.phrs.2014.03.011. Epub 2014 Apr 18.

PMID:
24747832
8.

Basolateral expression of GRP94 in parietal cells of gastric mucosa.

Arin RM, Rueda Y, Casis O, Gallego M, Vallejo AI, Ochoa B.

Biochemistry (Mosc). 2014 Jan;79(1):8-15. doi: 10.1134/S0006297914010027.

9.

Adrenergic regulation of cardiac ionic channels: role of membrane microdomains in the regulation of kv4 channels.

Gallego M, Alday A, Alonso H, Casis O.

Biochim Biophys Acta. 2014 Feb;1838(2):692-9. doi: 10.1016/j.bbamem.2013.06.025. Epub 2013 Jun 28. Review.

10.

Mechanisms responsible for the trophic effect of beta-adrenoceptors on the I(to) current density in type 1 diabetic rat cardiomyocytes.

Setién R, Alday A, Diaz-Asensio C, Urrutia J, Gallego M, Casis O.

Cell Physiol Biochem. 2013;31(1):25-36. doi: 10.1159/000343346. Epub 2013 Jan 14.

11.

Improvement of the metabolic status recovers cardiac potassium channel synthesis in experimental diabetes.

Torres-Jacome J, Gallego M, Rodríguez-Robledo JM, Sanchez-Chapula JA, Casis O.

Acta Physiol (Oxf). 2013 Mar;207(3):447-59. doi: 10.1111/apha.12043. Epub 2012 Dec 27.

PMID:
23181465
12.

A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents.

Hu D, Barajas-Martínez H, Medeiros-Domingo A, Crotti L, Veltmann C, Schimpf R, Urrutia J, Alday A, Casis O, Pfeiffer R, Burashnikov E, Caceres G, Tester DJ, Wolpert C, Borggrefe M, Schwartz P, Ackerman MJ, Antzelevitch C.

Heart Rhythm. 2012 May;9(5):760-9. doi: 10.1016/j.hrthm.2011.12.006. Epub 2011 Dec 7.

13.

Kv7 channels can function without constitutive calmodulin tethering.

Gómez-Posada JC, Aivar P, Alberdi A, Alaimo A, Etxeberría A, Fernández-Orth J, Zamalloa T, Roura-Ferrer M, Villace P, Areso P, Casis O, Villarroel A.

PLoS One. 2011;6(9):e25508. doi: 10.1371/journal.pone.0025508. Epub 2011 Sep 28.

14.

Mechanisms responsible for the altered cardiac repolarization dispersion in experimental hypothyroidism.

Ferrer T, Arín RM, Casis E, Torres-Jacome J, Sanchez-Chapula JA, Casis O.

Acta Physiol (Oxf). 2012 Apr;204(4):502-12. doi: 10.1111/j.1748-1716.2011.02364.x. Epub 2011 Oct 17.

PMID:
21933354
15.

LQT5 masquerading as LQT2: a dominant negative effect of KCNE1-D85N rare polymorphism on KCNH2 current.

Nof E, Barajas-Martinez H, Eldar M, Urrutia J, Caceres G, Rosenfeld G, Bar-Lev D, Feinberg M, Burashnikov E, Casis O, Hu D, Glikson M, Antzelevitch C.

Europace. 2011 Oct;13(10):1478-83. doi: 10.1093/europace/eur184. Epub 2011 Jun 28.

16.

α1-adrenoceptors regulate only the caveolae-located subpopulation of cardiac K(V)4 channels.

Alday A, Urrutia J, Gallego M, Casis O.

Channels (Austin). 2010 May-Jun;4(3):168-78.

PMID:
20224290
17.

Transient outward potassium channel regulation in healthy and diabetic hearts.

Gallego M, Alday A, Urrutia J, Casis O.

Can J Physiol Pharmacol. 2009 Feb;87(2):77-83. doi: 10.1139/Y08-106. Review.

PMID:
19234570
18.

Reduced calmodulin expression accelerates transient outward potassium current inactivation in diabetic rat heart.

Gallego M, Fernández D, Ahyayauch H, Casis E, Casis O.

Cell Physiol Biochem. 2008;22(5-6):625-34. doi: 10.1159/000185546. Epub 2008 Dec 9.

19.

Type 1 diabetes alters brain cannabinoid receptor expression and phosphorylation status in rats.

Díaz-Asensio C, Setién R, Echevarría E, Casis L, Casis E, Garrido A, Casis O.

Horm Metab Res. 2008 Jul;40(7):454-8. doi: 10.1055/s-2008-1065323. Epub 2008 Mar 27.

PMID:
18401837
20.

Changes in erythrocyte morphology induced by imipramine and chlorpromazine.

Ahyayaucha H, Gallego M, Casis O, Bennouna M.

J Physiol Biochem. 2006 Sep;62(3):199-205.

PMID:
17451161
21.

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.

Antzelevitch C, Pollevick GD, Cordeiro JM, Casis O, Sanguinetti MC, Aizawa Y, Guerchicoff A, Pfeiffer R, Oliva A, Wollnik B, Gelber P, Bonaros EP Jr, Burashnikov E, Wu Y, Sargent JD, Schickel S, Oberheiden R, Bhatia A, Hsu LF, Haïssaguerre M, Schimpf R, Borggrefe M, Wolpert C.

Circulation. 2007 Jan 30;115(4):442-9. Epub 2007 Jan 15.

22.

Differential modulation of Kv4.2 and Kv4.3 channels by calmodulin-dependent protein kinase II in rat cardiac myocytes.

Colinas O, Gallego M, Setién R, López-López JR, Pérez-García MT, Casis O.

Am J Physiol Heart Circ Physiol. 2006 Oct;291(4):H1978-87. Epub 2006 Apr 28.

23.

DITPA restores the repolarizing potassium currents Itof and Iss in cardiac ventricular myocytes of diabetic rats.

Ferrer T, Gallego M, Madrigal-Quiñónez R, Torres-Jácome J, Navarro-Polanco R, Cásis O, Sánchez-Chapula JA.

Life Sci. 2006 Jul 24;79(9):883-9. Epub 2006 Mar 21.

PMID:
16616210
24.

Mechanism of action of a novel human ether-a-go-go-related gene channel activator.

Casis O, Olesen SP, Sanguinetti MC.

Mol Pharmacol. 2006 Feb;69(2):658-65. Epub 2005 Nov 11.

PMID:
16284303
25.

alpha1-Adrenoceptors stimulate a Galphas protein and reduce the transient outward K+ current via a cAMP/PKA-mediated pathway in the rat heart.

Gallego M, Setién R, Puebla L, Boyano-Adánez Mdel C, Arilla E, Casis O.

Am J Physiol Cell Physiol. 2005 Mar;288(3):C577-85. Epub 2004 Oct 20.

26.

Diabetic cardiomyopathy: electromechanical cellular alterations.

Casis O, Echevarria E.

Curr Vasc Pharmacol. 2004 Jul;2(3):237-48. Review.

PMID:
15320822
27.

Diabetes-induced biochemical changes in central and peripheral catecholaminergic systems.

Gallego M, Setién R, Izquierdo MJ, Casis O, Casis E.

Physiol Res. 2003;52(6):735-41.

28.

Blood pressure responsiveness to sympathetic agonists in anaesthetised diabetic rats.

Gallego M, Espiña L, Casis O.

J Physiol Biochem. 2002 Jun;58(2):87-93.

PMID:
12435083
29.

Imipramine, mianserine and maprotiline block delayed rectifier potassium current in ventricular myocytes.

Casis O, Gallego M, Sánchez-Chapula JA.

Pharmacol Res. 2002 Feb;45(2):141-6.

PMID:
11846627
30.

Spironolactone and captopril attenuates isoproterenol-induced cardiac remodelling in rats.

Gallego M, Espiña L, Vegas L, Echevarria E, Iriarte MM, Casis O.

Pharmacol Res. 2001 Oct;44(4):311-5.

PMID:
11592866
31.

Regulation of cardiac transient outward potassium current by norepinephrine in normal and diabetic rats.

Gallego M, Casis O.

Diabetes Metab Res Rev. 2001 Jul-Aug;17(4):304-9.

PMID:
11544615
32.

Toluene alters mu-opioid receptor expression in the rat brainstem.

Saracibar G, Hernandez ML, Echevarria E, Barbero I, Gutierrez A, Casis O.

Ind Health. 2001 Jul;39(3):231-4.

33.

Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats.

Gallego M, Casis E, Izquierdo MJ, Casis O.

Pflugers Arch. 2000 Nov;441(1):102-7.

PMID:
11205047
34.

Effects of amphetamine on calcium and potassium currents in rat heart.

Casis O, Espiña L, Gallego M.

J Cardiovasc Pharmacol. 2000 Sep;36(3):390-5.

PMID:
10975598
35.

Effects of diabetic cardiomyopathy on regional electrophysiologic characteristics of rat ventricle.

Casis O, Gallego M, Iriarte M, Sánchez-Chapula JA.

Diabetologia. 2000 Jan;43(1):101-9.

PMID:
10672450
36.

Effects of fluoxetine administration on mu-opoid receptor immunostaining in the rat forebrain.

de Gandarias JM, Echevarría E, Acebes I, Abecia LC, Casis O, Casis L.

Brain Res. 1999 Jan 30;817(1-2):236-40.

PMID:
9889376
37.

Imipramine inhibits soluble enkephalin-degrading aminopeptidase activity in vitro.

Gallego M, Casis L, Casis O.

Eur J Pharmacol. 1998 Oct 30;360(1):113-6.

PMID:
9845280
38.

Mechanism of block of cardiac transient outward K+ current (I(to)) by antidepressant drugs.

Casis O, Sánchez-Chapula JA.

J Cardiovasc Pharmacol. 1998 Oct;32(4):527-34.

PMID:
9781920
39.

Disopyramide, imipramine, and amitriptyline bind to a common site on the transient outward K+ channel.

Casis O, Sánchez-Chapula JA.

J Cardiovasc Pharmacol. 1998 Oct;32(4):521-6.

PMID:
9781919
40.

Differences in regional distribution of K+ current densities in rat ventricle.

Casis O, Iriarte M, Gallego M, Sánchez-Chapula JA.

Life Sci. 1998;63(5):391-400.

PMID:
9714426
41.

Subcellular analysis of Tyr-aminopeptidase activities in the developing rat cerebellum.

de Gandarias JM, Irazusta J, Gil J, Gallego M, Casis O, Casis L.

Brain Res Dev Brain Res. 1997 Mar 17;99(1):66-71.

PMID:
9088567
42.

Interaction mechanisms of imipramine and desipramine with enkephalin-degrading aminopeptidases in vitro.

de Gandarias JM, Casis O, Varona A, Gallego M, Irazusta J, Casis L.

Life Sci. 1997;61(21):PL 321-6.

PMID:
9395259
43.

Developmental changes in telencephalic enkephalinergic neurones.

Echevarria E, Casis O, Clemente JM, Silio M, Serrano R.

Int J Dev Biol. 1996;Suppl 1:163S-164S. No abstract available.

44.

Brain pyroglutamate-peptidase I activity develops differently in hypothalamus and pituitary gland of the female and male rats.

Casis L, Fernández D, Casis O, Gallego M, Echevarria E, Silio M.

Int J Dev Biol. 1996;Suppl 1:139S-140S. No abstract available.

46.

Effects of the novel potassium channel opener, UR-8225, on contractile responses in rat isolated smooth muscle.

Perez-Vizcaino F, Casis O, Rodriguez R, Gomez LA, Garcia Rafanell J, Tamargo J.

Br J Pharmacol. 1993 Nov;110(3):1165-71.

47.

Effects of lisinopril on electromechanical properties and membrane currents in guinea-pig cardiac preparations.

Valenzuela C, Pérez O, Casis O, Duarte J, Pérez-Vizcaino F, Delpón E, Tamargo J.

Br J Pharmacol. 1993 Jul;109(3):873-9.

48.

Pyroglutamyl [correction of Pyroglutamil] -peptidase I activity in the cortex of the cat brain during development.

de Gandarias JM, Casis O, Echevarría E, Irazusta J, Casis L.

Int J Dev Biol. 1992 Jun;36(2):335-7.

49.

Effect of phenobarbital administration on the activity of two neuropeptide-degrading enzymes in several brain areas of the rat.

de Gandarias JM, Múgica J, Echevarría E, Irazusta J, Casis O, Casis L.

Arzneimittelforschung. 1992 May;42(5):608-10.

PMID:
1530671
50.

Effect of subacute benzene exposure on the activity of two neuropeptide-degrading enzymes in the rat brain.

de Gandarias JM, Casis O, Irazusta J, Echevarría E, Casis L.

Arch Environ Contam Toxicol. 1992 Apr;22(3):345-8.

PMID:
1616320

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