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Items: 1 to 50 of 88

1.

Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes.

Casini S, Marchal GA, Kawasaki M, Nariswari FA, Portero V, van den Berg NWE, Guan K, Driessen AHG, Veldkamp MW, Mengarelli I, de Groot JR, Verkerk AO, Remme CA.

Cardiovasc Drugs Ther. 2020 Jan 8. doi: 10.1007/s10557-019-06925-6. [Epub ahead of print]

PMID:
31916131
2.

Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice.

Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA.

Int J Mol Sci. 2019 Oct 11;20(20). pii: E5033. doi: 10.3390/ijms20205033.

3.

Insights Into Cetacean Immunology: Do Ecological and Biological Factors Make the Difference?

Marsili L, Di Guardo G, Mazzariol S, Casini S.

Front Immunol. 2019 May 31;10:1219. doi: 10.3389/fimmu.2019.01219. eCollection 2019.

4.

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C.

Sci Transl Med. 2019 May 22;11(493). pii: eaav7770. doi: 10.1126/scitranslmed.aav7770.

PMID:
31118294
5.

Microplastics occurrence in edible fish species (Mullus barbatus and Merluccius merluccius) collected in three different geographical sub-areas of the Mediterranean Sea.

Giani D, Baini M, Galli M, Casini S, Fossi MC.

Mar Pollut Bull. 2019 Mar;140:129-137. doi: 10.1016/j.marpolbul.2019.01.005. Epub 2019 Jan 23.

PMID:
30803626
6.

An immune response-based approach to evaluate physiological stress in rehabilitating loggerhead sea turtle.

Caliani I, Poggioni L, D'Agostino A, Fossi MC, Casini S.

Vet Immunol Immunopathol. 2019 Jan;207:18-24. doi: 10.1016/j.vetimm.2018.11.013. Epub 2018 Nov 20.

PMID:
30593346
7.

Large-Scale Simulation of the Phenotypical Variability Induced by Loss-of-Function Long QT Mutations in Human Induced Pluripotent Stem Cell Cardiomyocytes.

Paci M, Casini S, Bellin M, Hyttinen J, Severi S.

Int J Mol Sci. 2018 Nov 13;19(11). pii: E3583. doi: 10.3390/ijms19113583.

8.

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel.

Veldkamp MW, Geuzebroek GSC, Baartscheer A, Verkerk AO, Schumacher CA, Suarez GG, Berger WR, Casini S, van Amersfoorth SCM, Scholman KT, Driessen AHG, Belterman CNW, van Ginneken ACG, de Groot JR, de Bakker JMT, Remme CA, Boukens BJ, Coronel R.

Nat Commun. 2018 Oct 19;9(1):4357. doi: 10.1038/s41467-018-06530-5.

9.

First ecotoxicological assessment of Caretta caretta (Linnaeus, 1758) in the Mediterranean Sea using an integrated nondestructive protocol.

Casini S, Caliani I, Giannetti M, Marsili L, Maltese S, Coppola D, Bianchi N, Campani T, Ancora S, Caruso C, Furii G, Parga M, D'Agostino A, Fossi MC.

Sci Total Environ. 2018 Aug 1;631-632:1221-1233. doi: 10.1016/j.scitotenv.2018.03.111. Epub 2018 Mar 16.

PMID:
29727947
10.

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.

Anderson DJ, Kaplan DI, Bell KM, Koutsis K, Haynes JM, Mills RJ, Phelan DG, Qian EL, Leitoguinho AR, Arasaratnam D, Labonne T, Ng ES, Davis RP, Casini S, Passier R, Hudson JE, Porrello ER, Costa MW, Rafii A, Curl CL, Delbridge LM, Harvey RP, Oshlack A, Cheung MM, Mummery CL, Petrou S, Elefanty AG, Stanley EG, Elliott DA.

Nat Commun. 2018 Apr 10;9(1):1373. doi: 10.1038/s41467-018-03714-x.

11.

KV4.3 Expression Modulates NaV1.5 Sodium Current.

Portero V, Wilders R, Casini S, Charpentier F, Verkerk AO, Remme CA.

Front Physiol. 2018 Mar 12;9:178. doi: 10.3389/fphys.2018.00178. eCollection 2018.

12.

Bioindicators for monitoring marine litter ingestion and its impacts on Mediterranean biodiversity.

Fossi MC, Pedà C, Compa M, Tsangaris C, Alomar C, Claro F, Ioakeimidis C, Galgani F, Hema T, Deudero S, Romeo T, Battaglia P, Andaloro F, Caliani I, Casini S, Panti C, Baini M.

Environ Pollut. 2018 Jun;237:1023-1040. doi: 10.1016/j.envpol.2017.11.019. Epub 2017 Nov 16. Review.

PMID:
29153726
13.

Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.

Casini S, Verkerk AO, Remme CA.

Cardiovasc Drugs Ther. 2017 Jun;31(3):325-344. doi: 10.1007/s10557-017-6735-0. Review.

14.

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.

Portero V, Casini S, Hoekstra M, Verkerk AO, Mengarelli I, Belardinelli L, Rajamani S, Wilde AAM, Bezzina CR, Veldkamp MW, Remme CA.

Cardiovasc Res. 2017 Jun 1;113(7):829-838. doi: 10.1093/cvr/cvx077.

PMID:
28430892
16.

Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A.

Kosmidis G, Veerman CC, Casini S, Verkerk AO, van de Pas S, Bellin M, Wilde AA, Mummery CL, Bezzina CR.

Circ Arrhythm Electrophysiol. 2016 Nov;9(11). pii: e004227.

PMID:
27784737
17.

Impact of Raw and Bioaugmented Olive-Mill Wastewater and Olive-Mill Solid Waste on the Content of Photosynthetic Molecules in Tobacco Plants.

Parrotta L, Campani T, Casini S, Romi M, Cai G.

J Agric Food Chem. 2016 Aug 3;64(30):5971-84. doi: 10.1021/acs.jafc.6b00725. Epub 2016 Jul 20.

PMID:
27399282
18.

[Percutaneous transcatheter closure of an aorta to left atrium fistula with an Amplatzer septal occluder in a patient with a mitral bioprosthesis].

Casini S, Fineschi M, Cameli M, Geyer A, Mandoli GE, Lunghetti S, Mondillo S, Pierli C.

G Ital Cardiol (Rome). 2016 May;17(5):391-2. doi: 10.1714/2252.24272. Italian.

PMID:
27310914
19.

Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure.

Kosmidis G, Bellin M, Ribeiro MC, van Meer B, Ward-van Oostwaard D, Passier R, Tertoolen LG, Mummery CL, Casini S.

Biochem Biophys Res Commun. 2015 Nov 27;467(4):998-1005. doi: 10.1016/j.bbrc.2015.10.026. Epub 2015 Oct 9.

PMID:
26456652
20.

Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

Veerman CC, Kosmidis G, Mummery CL, Casini S, Verkerk AO, Bellin M.

Stem Cells Dev. 2015 May 1;24(9):1035-52. doi: 10.1089/scd.2014.0533. Epub 2015 Feb 25. Review.

PMID:
25583389
21.

Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones.

Dambrot C, Buermans HP, Varga E, Kosmidis G, Langenberg K, Casini S, Elliott DA, Dinnyes A, Atsma DE, Mummery CL, Braam SR, Davis RP.

Exp Cell Res. 2014 Oct 1;327(2):297-306. doi: 10.1016/j.yexcr.2014.05.001. Epub 2014 May 13.

PMID:
24836851
22.

Pilot study on levels of chemical contaminants and porphyrins in Caretta caretta from the Mediterranean Sea.

Guerranti C, Baini M, Casini S, Focardi SE, Giannetti M, Mancusi C, Marsili L, Perra G, Fossi MC.

Mar Environ Res. 2014 Sep;100:33-7. doi: 10.1016/j.marenvres.2014.01.004. Epub 2014 Feb 1.

PMID:
24553348
23.

PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.

Birket MJ, Casini S, Kosmidis G, Elliott DA, Gerencser AA, Baartscheer A, Schumacher C, Mastroberardino PG, Elefanty AG, Stanley EG, Mummery CL.

Stem Cell Reports. 2013 Dec 12;1(6):560-74. doi: 10.1016/j.stemcr.2013.11.008. eCollection 2013.

24.

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.

Bellin M, Casini S, Davis RP, D'Aniello C, Haas J, Ward-van Oostwaard D, Tertoolen LG, Jung CB, Elliott DA, Welling A, Laugwitz KL, Moretti A, Mummery CL.

EMBO J. 2013 Dec 11;32(24):3161-75. doi: 10.1038/emboj.2013.240. Epub 2013 Nov 8.

25.

Plastic litter in the sea.

Depledge MH, Galgani F, Panti C, Caliani I, Casini S, Fossi MC.

Mar Environ Res. 2013 Dec;92:279-81. doi: 10.1016/j.marenvres.2013.10.002. Epub 2013 Oct 11.

PMID:
24157269
26.

First application of comet assay in blood cells of Mediterranean loggerhead sea turtle (Caretta caretta).

Caliani I, Campani T, Giannetti M, Marsili L, Casini S, Fossi MC.

Mar Environ Res. 2014 May;96:68-72. doi: 10.1016/j.marenvres.2013.09.008. Epub 2013 Sep 22.

PMID:
24112743
27.

Presence of plastic debris in loggerhead turtle stranded along the Tuscany coasts of the Pelagos Sanctuary for Mediterranean Marine Mammals (Italy).

Campani T, Baini M, Giannetti M, Cancelli F, Mancusi C, Serena F, Marsili L, Casini S, Fossi MC.

Mar Pollut Bull. 2013 Sep 15;74(1):225-30. doi: 10.1016/j.marpolbul.2013.06.053. Epub 2013 Jul 26.

PMID:
23896406
28.

The Pelagos Sanctuary for Mediterranean marine mammals: Marine Protected Area (MPA) or marine polluted area? The case study of the striped dolphin (Stenella coeruleoalba).

Fossi MC, Panti C, Marsili L, Maltese S, Spinsanti G, Casini S, Caliani I, Gaspari S, Muñoz-Arnanz J, Jimenez B, Finoia MG.

Mar Pollut Bull. 2013 May 15;70(1-2):64-72. doi: 10.1016/j.marpolbul.2013.02.013. Epub 2013 Mar 5.

PMID:
23465620
29.

An "ex vivo" model to evaluate toxicological responses to mixtures of contaminants in cetaceans: integumentum biopsy slices.

Fossi MC, Casini S, Maltese S, Panti C, Spinsanti G, Marsili L.

Environ Toxicol. 2014 Oct;29(10):1107-21. doi: 10.1002/tox.21841. Epub 2013 Jan 22.

PMID:
23339137
30.

Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes.

Braam SR, Tertoolen L, Casini S, Matsa E, Lu HR, Teisman A, Passier R, Denning C, Gallacher DJ, Towart R, Mummery CL.

Stem Cell Res. 2013 Jan;10(1):48-56. doi: 10.1016/j.scr.2012.08.007. Epub 2012 Sep 7.

31.

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease.

Davis RP, Casini S, van den Berg CW, Hoekstra M, Remme CA, Dambrot C, Salvatori D, Oostwaard DW, Wilde AA, Bezzina CR, Verkerk AO, Freund C, Mummery CL.

Circulation. 2012 Jun 26;125(25):3079-91. doi: 10.1161/CIRCULATIONAHA.111.066092. Epub 2012 May 30.

PMID:
22647976
32.

The role of large marine vertebrates in the assessment of the quality of pelagic marine ecosystems.

Fossi MC, Casini S, Caliani I, Panti C, Marsili L, Viarengo A, Giangreco R, Notarbartolo di Sciara G, Serena F, Ouerghi A, Depledge MH.

Mar Environ Res. 2012 Jun;77:156-8. doi: 10.1016/j.marenvres.2012.03.003. Epub 2012 Mar 22.

PMID:
22494853
33.
34.

Decreased inward rectification of Kir2.1 channels is a novel mechanism underlying the short QT syndrome.

Casini S, Postma AV.

Cardiovasc Res. 2012 Mar 15;93(4):535-6. doi: 10.1093/cvr/cvs084. Epub 2012 Feb 5. No abstract available.

PMID:
22311718
35.

Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development.

Davis RP, van den Berg CW, Casini S, Braam SR, Mummery CL.

Trends Mol Med. 2011 Sep;17(9):475-84. doi: 10.1016/j.molmed.2011.05.001. Epub 2011 Jun 22. Review.

PMID:
21703926
36.

Ecotoxicological diagnosis of striped dolphin (Stenella coeruleoalba) from the Mediterranean basin by skin biopsy and gene expression approach.

Panti C, Spinsanti G, Marsili L, Casini S, Frati F, Fossi MC.

Ecotoxicology. 2011 Nov;20(8):1791-800. doi: 10.1007/s10646-011-0713-2. Epub 2011 Jun 22.

PMID:
21695511
37.

Long-term outcome after drug-eluting stents implantation: target lesion versus nontarget lesion repeated intervention.

Fineschi M, Zacà V, Gori T, Casini S, Sinicropi G, Pierli C.

Int J Cardiol. 2010 Nov 19;145(2):322-324. doi: 10.1016/j.ijcard.2009.11.049. Epub 2010 Jan 6.

PMID:
20051300
38.

A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico).

Fossi MC, Urban J, Casini S, Maltese S, Spinsanti G, Panti C, Porcelloni S, Panigada S, Lauriano G, Niño-Torres C, Rojas-Bracho L, Jimenez B, Muñoz-Arnanz J, Marsili L.

Mar Environ Res. 2010;69 Suppl:S17-20. doi: 10.1016/j.marenvres.2009.10.006. Epub 2009 Nov 13.

PMID:
19913904
39.

Tubulin polymerization modifies cardiac sodium channel expression and gating.

Casini S, Tan HL, Demirayak I, Remme CA, Amin AS, Scicluna BP, Chatyan H, Ruijter JM, Bezzina CR, van Ginneken AC, Veldkamp MW.

Cardiovasc Res. 2010 Mar 1;85(4):691-700. doi: 10.1093/cvr/cvp352. Epub 2009 Oct 26.

PMID:
19861310
40.

The Italian wall lizard (Podarcis sicula) as a bioindicator of oil field activity.

Marsili L, Casini S, Mori G, Ancora S, Bianchi N, D'Agostino A, Ferraro M, Fossi MC.

Sci Total Environ. 2009 May 15;407(11):3597-604. doi: 10.1016/j.scitotenv.2009.01.035. Epub 2009 Feb 20.

PMID:
19232674
41.

Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes.

Casini S, Verkerk AO, van Borren MM, van Ginneken AC, Veldkamp MW, de Bakker JM, Tan HL.

Cardiovasc Res. 2009 Jan 1;81(1):72-81. doi: 10.1093/cvr/cvn274. Epub 2008 Oct 1.

PMID:
18829699
42.

Genotoxic effects of produced waters in mosquito fish (Gambusia affinis).

Caliani I, Porcelloni S, Mori G, Frenzilli G, Ferraro M, Marsili L, Casini S, Fossi MC.

Ecotoxicology. 2009 Jan;18(1):75-80. doi: 10.1007/s10646-008-0259-0. Epub 2008 Sep 1.

PMID:
18763036
43.

Use of immunofluorescence technique in cultured fibroblasts from Mediterranean cetaceans as new "in vitro" tool to investigate effects of environmental contaminants.

Marsili L, Casini S, Bucalossi D, Porcelloni S, Maltese S, Fossi MC.

Mar Environ Res. 2008 Jul;66(1):151-3. doi: 10.1016/j.marenvres.2008.02.068. Epub 2008 Mar 4.

PMID:
18396327
44.

First detection of CYP1A1 and CYP2B induction in Mediterranean cetacean skin biopsies and cultured fibroblasts by Western blot analysis.

Fossi MC, Casini S, Bucalossi D, Marsili L.

Mar Environ Res. 2008 Jul;66(1):3-6. doi: 10.1016/j.marenvres.2008.02.006. Epub 2008 Feb 26.

PMID:
18384870
45.

Selection of reliable reference genes for qRT-PCR studies on cetacean fibroblast cultures exposed to OCs, PBDEs, and 17beta-estradiol.

Spinsanti G, Panti C, Bucalossi D, Marsili L, Casini S, Frati F, Fossi MC.

Aquat Toxicol. 2008 May 1;87(3):178-86. doi: 10.1016/j.aquatox.2008.01.018. Epub 2008 Feb 8.

PMID:
18339435
46.

Beneficial effect of post-procedural abciximab in patients undergoing primary coronary angioplasty and presenting with the no-reflow phenomenon.

Picchi A, Zaca V, Focardi M, Fineschi M, Sinicropi G, Casini S, Buti A, Pierli C, Mondillo S, Marzilli M.

Acute Card Care. 2008;10(2):100-3.

PMID:
17926148
47.

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation.

Casini S, Tan HL, Bhuiyan ZA, Bezzina CR, Barnett P, Cerbai E, Mugelli A, Wilde AA, Veldkamp MW.

Cardiovasc Res. 2007 Dec 1;76(3):418-29. Epub 2007 Aug 22.

PMID:
17854786
48.

Symptomatic failure after sirolimus-eluting stent implantation: a rare but challenging condition.

Fineschi M, Gori T, Pierli C, Casini S, Sinicropi G, Buti A, Iadanza A, Bravi A.

Can J Cardiol. 2007 Feb;23(2):139-42.

49.

Vitellogenin and zona radiata proteins as biomarkers of endocrine disruption in peregrine falcon (Falco peregrinus).

Jiménez B, Mori G, Concejero MA, Merino R, Casini S, Fossi MC.

Chemosphere. 2007 Apr;67(9):S375-8. Epub 2007 Jan 16.

PMID:
17223181
50.

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