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Items: 1 to 50 of 96

1.
2.

Methylobacterium extorquens RSH Enzyme Synthesizes (p)ppGpp and pppApp in vitro and in vivo, and Leads to Discovery of pppApp Synthesis in Escherichia coli.

Sobala M, Bruhn-Olszewska B, Cashel M, Potrykus K.

Front Microbiol. 2019 Apr 24;10:859. doi: 10.3389/fmicb.2019.00859. eCollection 2019.

3.

Development of Attribution-Based Scales Associated With Proactive, Reactive, and Acquisitive Offending.

Kroner DG, Lacey BA, Cashel ML.

J Interpers Violence. 2018 Dec 17:886260518818425. doi: 10.1177/0886260518818425. [Epub ahead of print]

PMID:
30556463
4.

Puzzling conformational changes affecting proteins binding to the RNA polymerase.

Fernández-Coll L, Potrykus K, Cashel M.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12550-12552. doi: 10.1073/pnas.1818361115. Epub 2018 Nov 29. No abstract available.

5.

Contributions of SpoT Hydrolase, SpoT Synthetase, and RelA Synthetase to Carbon Source Diauxic Growth Transitions in Escherichia coli.

Fernández-Coll L, Cashel M.

Front Microbiol. 2018 Aug 3;9:1802. doi: 10.3389/fmicb.2018.01802. eCollection 2018.

6.

Growth at best and worst of times.

Potrykus K, Cashel M.

Nat Microbiol. 2018 Aug;3(8):862-863. doi: 10.1038/s41564-018-0207-6. No abstract available.

PMID:
30046172
7.

Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro.

Bruhn-Olszewska B, Molodtsov V, Sobala M, Dylewski M, Murakami KS, Cashel M, Potrykus K.

Biochim Biophys Acta Gene Regul Mech. 2018 Aug;1861(8):731-742. doi: 10.1016/j.bbagrm.2018.07.005. Epub 2018 Jul 18.

8.

The E. coli Global Regulator DksA Reduces Transcription during T4 Infection.

Patterson-West J, James TD, Fernández-Coll L, Iben JR, Moon K, Knipling L, Cashel M, Hinton DM.

Viruses. 2018 Jun 6;10(6). pii: E308. doi: 10.3390/v10060308.

9.

Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.

Molodtsov V, Sineva E, Zhang L, Huang X, Cashel M, Ades SE, Murakami KS.

Mol Cell. 2018 Mar 1;69(5):828-839.e5. doi: 10.1016/j.molcel.2018.01.035. Epub 2018 Feb 22.

10.

ppGpp couples transcription to DNA repair in E. coli.

Kamarthapu V, Epshtein V, Benjamin B, Proshkin S, Mironov A, Cashel M, Nudler E.

Science. 2016 May 20;352(6288):993-6. doi: 10.1126/science.aad6945.

11.

From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis.

Gaca AO, Kudrin P, Colomer-Winter C, Beljantseva J, Liu K, Anderson B, Wang JD, Rejman D, Potrykus K, Cashel M, Hauryliuk V, Lemos JA.

J Bacteriol. 2015 Sep;197(18):2908-19. doi: 10.1128/JB.00324-15. Epub 2015 Jun 29.

12.

Differential regulation by ppGpp versus pppGpp in Escherichia coli.

Mechold U, Potrykus K, Murphy H, Murakami KS, Cashel M.

Nucleic Acids Res. 2013 Jul;41(12):6175-89. doi: 10.1093/nar/gkt302. Epub 2013 Apr 25.

13.

Effects on growth by changes of the balance between GreA, GreB, and DksA suggest mutual competition and functional redundancy in Escherichia coli.

Vinella D, Potrykus K, Murphy H, Cashel M.

J Bacteriol. 2012 Jan;194(2):261-73. doi: 10.1128/JB.06238-11. Epub 2011 Nov 4.

14.

Circuitry linking the Csr and stringent response global regulatory systems.

Edwards AN, Patterson-Fortin LM, Vakulskas CA, Mercante JW, Potrykus K, Vinella D, Camacho MI, Fields JA, Thompson SA, Georgellis D, Cashel M, Babitzke P, Romeo T.

Mol Microbiol. 2011 Jun;80(6):1561-80. doi: 10.1111/j.1365-2958.2011.07663.x. Epub 2011 May 5.

15.

ppGpp is the major source of growth rate control in E. coli.

Potrykus K, Murphy H, Philippe N, Cashel M.

Environ Microbiol. 2011 Mar;13(3):563-575. doi: 10.1111/j.1462-2920.2010.02357.x. Epub 2010 Oct 15.

16.

A mutation within the β subunit of Escherichia coli RNA polymerase impairs transcription from bacteriophage T4 middle promoters.

James TD, Cashel M, Hinton DM.

J Bacteriol. 2010 Nov;192(21):5580-7. doi: 10.1128/JB.00338-10. Epub 2010 Aug 20.

17.

Imprecise transcription termination within Escherichia coli greA leader gives rise to an array of short transcripts, GraL.

Potrykus K, Murphy H, Chen X, Epstein JA, Cashel M.

Nucleic Acids Res. 2010 Mar;38(5):1636-51. doi: 10.1093/nar/gkp1150. Epub 2009 Dec 14.

18.

TraR, a homolog of a RNAP secondary channel interactor, modulates transcription.

Blankschien MD, Potrykus K, Grace E, Choudhary A, Vinella D, Cashel M, Herman C.

PLoS Genet. 2009 Jan;5(1):e1000345. doi: 10.1371/journal.pgen.1000345. Epub 2009 Jan 16.

19.

Synthetic growth phenotypes of Escherichia coli lacking ppGpp and transketolase A (tktA) are due to ppGpp-mediated transcriptional regulation of tktB.

Harinarayanan R, Murphy H, Cashel M.

Mol Microbiol. 2008 Aug;69(4):882-94. doi: 10.1111/j.1365-2958.2008.06317.x. Epub 2008 Jun 4.

20.

(p)ppGpp: still magical?

Potrykus K, Cashel M.

Annu Rev Microbiol. 2008;62:35-51. doi: 10.1146/annurev.micro.62.081307.162903. Review.

PMID:
18454629
21.

Selective fluorescent chemosensor for the bacterial alarmone (p)ppGpp.

Rhee HW, Lee CR, Cho SH, Song MR, Cashel M, Choy HE, Seok YJ, Hong JI.

J Am Chem Soc. 2008 Jan 23;130(3):784-5. doi: 10.1021/ja0759139. Epub 2008 Jan 1.

PMID:
18166051
22.

Antagonistic regulation of Escherichia coli ribosomal RNA rrnB P1 promoter activity by GreA and DksA.

Potrykus K, Vinella D, Murphy H, Szalewska-Palasz A, D'Ari R, Cashel M.

J Biol Chem. 2006 Jun 2;281(22):15238-48. Epub 2006 Apr 5.

23.

Iron limitation induces SpoT-dependent accumulation of ppGpp in Escherichia coli.

Vinella D, Albrecht C, Cashel M, D'Ari R.

Mol Microbiol. 2005 May;56(4):958-70.

24.

Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response [corrected].

Hogg T, Mechold U, Malke H, Cashel M, Hilgenfeld R.

Cell. 2004 Apr 2;117(1):57-68. Erratum in: Cell. 2004 Apr 30;117(3):415.

25.

Isolation of RNA polymerase suppressors of a (p)ppGpp deficiency.

Murphy H, Cashel M.

Methods Enzymol. 2003;371:596-601. No abstract available.

PMID:
14712731
26.

Structured group therapy for posttraumatic stress disorder in incarcerated male juveniles.

Ovaert LB, Cashel ML, Sewell KW.

Am J Orthopsychiatry. 2003 Jul;73(3):294-301.

PMID:
12921210
27.

Changes in conserved region 3 of Escherichia coli sigma 70 reduce abortive transcription and enhance promoter escape.

Cashel M, Hsu LM, Hernandez VJ.

J Biol Chem. 2003 Feb 21;278(8):5539-47. Epub 2002 Dec 10.

28.

DksA affects ppGpp induction of RpoS at a translational level.

Brown L, Gentry D, Elliott T, Cashel M.

J Bacteriol. 2002 Aug;184(16):4455-65.

29.
30.

Evaluating PTSD in incarcerated male juveniles with the MMPI-A: an exploratory analysis.

Cashel ML, Ovaert L, Holliman NG.

J Clin Psychol. 2000 Dec;56(12):1535-49.

PMID:
11132569
31.

Selected amplification of the cell division genes ftsQ-ftsA-ftsZ in Escherichia coli.

Vinella D, Cashel M, D'Ari R.

Genetics. 2000 Dec;156(4):1483-92.

32.

Predictions of violent and total infractions among institutionalized male juvenile offenders.

Hicks MM, Rogers R, Cashel M.

J Am Acad Psychiatry Law. 2000;28(2):183-90.

PMID:
10888186
33.

Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.

Hou Z, Cashel M, Fromm HJ, Honzatko RB.

J Biol Chem. 1999 Jun 18;274(25):17505-10.

34.
35.
36.

Guanosine tetra- and pentaphosphate promote accumulation of inorganic polyphosphate in Escherichia coli.

Kuroda A, Murphy H, Cashel M, Kornberg A.

J Biol Chem. 1997 Aug 22;272(34):21240-3.

37.
38.

Mecillinam resistance in Escherichia coli is conferred by loss of a second activity of the AroK protein.

Vinella D, Gagny B, Joseleau-Petit D, D'Ari R, Cashel M.

J Bacteriol. 1996 Jul;178(13):3818-28.

40.

Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilis.

Mechold U, Cashel M, Steiner K, Gentry D, Malke H.

J Bacteriol. 1996 Mar;178(5):1401-11.

41.
42.

Cellular localization of the Escherichia coli SpoT protein.

Gentry DR, Cashel M.

J Bacteriol. 1995 Jul;177(13):3890-3.

43.

Synthesis of the stationary-phase sigma factor sigma s is positively regulated by ppGpp.

Gentry DR, Hernandez VJ, Nguyen LH, Jensen DB, Cashel M.

J Bacteriol. 1993 Dec;175(24):7982-9.

44.

Guanylate kinase of Escherichia coli K-12.

Gentry D, Bengra C, Ikehara K, Cashel M.

J Biol Chem. 1993 Jul 5;268(19):14316-21.

46.

Function of a relaxed-like state following temperature downshifts in Escherichia coli.

Jones PG, Cashel M, Glaser G, Neidhardt FC.

J Bacteriol. 1992 Jun;174(12):3903-14.

47.

The nucleotide sequence of recG, the distal spo operon gene in Escherichia coli K-12.

Kalman M, Murphy H, Cashel M.

Gene. 1992 Jan 2;110(1):95-9.

PMID:
1544582
49.
50.

Residual guanosine 3',5'-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations.

Xiao H, Kalman M, Ikehara K, Zemel S, Glaser G, Cashel M.

J Biol Chem. 1991 Mar 25;266(9):5980-90.

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