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Items: 1 to 50 of 57

1.

Lactobacillus gasseri APC 678 Reduces Shedding of the Pathogen Clostridium difficile in a Murine Model.

Quigley L, Coakley M, Alemayehu D, Rea MC, Casey PG, O'Sullivan Ó, Murphy E, Kiely B, Cotter PD, Hill C, Ross RP.

Front Microbiol. 2019 Feb 20;10:273. doi: 10.3389/fmicb.2019.00273. eCollection 2019.

2.

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection.

Las Heras V, Clooney AG, Ryan FJ, Cabrera-Rubio R, Casey PG, Hueston CM, Pinheiro J, Rudkin JK, Melgar S, Cotter PD, Hill C, Gahan CGM.

Microbiome. 2019 Jan 18;7(1):7. doi: 10.1186/s40168-019-0621-x.

3.

A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation.

O'Connell Motherway M, Houston A, O'Callaghan G, Reunanen J, O'Brien F, O'Driscoll T, Casey PG, de Vos WM, van Sinderen D, Shanahan F.

Mol Microbiol. 2019 Jan;111(1):287-301. doi: 10.1111/mmi.14155. Epub 2018 Dec 2.

PMID:
30352131
4.

Staying alive: growth and survival of Bifidobacterium animalis subsp. animalis under in vitro and in vivo conditions.

Egan M, Bottacini F, O'Connell Motherway M, Casey PG, Morrissey R, Melgar S, Faurie JM, Chervaux C, Smokvina T, van Sinderen D.

Appl Microbiol Biotechnol. 2018 Dec;102(24):10645-10663. doi: 10.1007/s00253-018-9413-7. Epub 2018 Oct 10.

PMID:
30306201
5.

Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut.

O'Connell Motherway M, O'Brien F, O'Driscoll T, Casey PG, Shanahan F, van Sinderen D.

Sci Rep. 2018 Jul 13;8(1):10627. doi: 10.1038/s41598-018-29034-0.

6.

A long and abundant non-coding RNA in Lactobacillus salivarius.

Cousin FJ, Lynch DB, Chuat V, Bourin MJB, Casey PG, Dalmasso M, Harris HMB, McCann A, O'Toole PW.

Microb Genom. 2017 Jul 17;3(9):e000126. doi: 10.1099/mgen.0.000126. eCollection 2017 Sep.

7.

Development of a Click Beetle Luciferase Reporter System for Enhanced Bioluminescence Imaging of Listeria monocytogenes: Analysis in Cell Culture and Murine Infection Models.

Ur Rahman S, Stanton M, Casey PG, Spagnuolo A, Bensi G, Hill C, Francis KP, Tangney M, Gahan CGM.

Front Microbiol. 2017 Sep 26;8:1797. doi: 10.3389/fmicb.2017.01797. eCollection 2017.

8.

Genome-Wide Search for Genes Required for Bifidobacterial Growth under Iron-Limitation.

Lanigan N, Bottacini F, Casey PG, O'Connell Motherway M, van Sinderen D.

Front Microbiol. 2017 May 31;8:964. doi: 10.3389/fmicb.2017.00964. eCollection 2017.

9.

The influence of rosuvastatin on the gastrointestinal microbiota and host gene expression profiles.

Nolan JA, Skuse P, Govindarajan K, Patterson E, Konstantinidou N, Casey PG, MacSharry J, Shanahan F, Stanton C, Hill C, Cotter PD, Joyce SA, Gahan CGM.

Am J Physiol Gastrointest Liver Physiol. 2017 May 1;312(5):G488-G497. doi: 10.1152/ajpgi.00149.2016. Epub 2017 Feb 16.

10.

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk.

Govindarajan K, MacSharry J, Casey PG, Shanahan F, Joyce SA, Gahan CG.

PLoS One. 2016 Dec 1;11(12):e0167319. doi: 10.1371/journal.pone.0167319. eCollection 2016.

11.

Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms.

Dowd GC, Bahey-El-Din M, Casey PG, Joyce SA, Hill C, Gahan CG.

Hum Vaccin Immunother. 2016 Aug 2;12(8):2059-2063. Epub 2016 Feb 23.

12.
13.

Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance.

Feehily C, Finnerty A, Casey PG, Hill C, Gahan CG, O'Byrne CP, Karatzas KA.

PLoS One. 2014 Nov 11;9(11):e112649. doi: 10.1371/journal.pone.0112649. eCollection 2014.

14.

Exopolysaccharide-producing probiotic Lactobacilli reduce serum cholesterol and modify enteric microbiota in ApoE-deficient mice.

London LE, Kumar AH, Wall R, Casey PG, O'Sullivan O, Shanahan F, Hill C, Cotter PD, Fitzgerald GF, Ross RP, Caplice NM, Stanton C.

J Nutr. 2014 Dec;144(12):1956-62. doi: 10.3945/jn.114.191627. Epub 2014 Oct 15.

PMID:
25320181
15.

Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003.

Christiaen SE, O'Connell Motherway M, Bottacini F, Lanigan N, Casey PG, Huys G, Nelis HJ, van Sinderen D, Coenye T.

PLoS One. 2014 May 28;9(5):e98111. doi: 10.1371/journal.pone.0098111. eCollection 2014.

16.

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.

Joyce SA, MacSharry J, Casey PG, Kinsella M, Murphy EF, Shanahan F, Hill C, Gahan CG.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7421-6. doi: 10.1073/pnas.1323599111. Epub 2014 May 5.

17.

Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract.

Rea MC, Alemayehu D, Casey PG, O'Connor PM, Lawlor PG, Walsh M, Shanahan F, Kiely B, Ross RP, Hill C.

Microbiology. 2014 Feb;160(Pt 2):439-45. doi: 10.1099/mic.0.068767-0. Epub 2013 Nov 28.

PMID:
24287693
18.

Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors.

Hanin A, Culligan EP, Casey PG, Bahey-El-Din M, Hill C, Gahan CG.

Hum Vaccin Immunother. 2014;10(2):333-7. doi: 10.4161/hv.26954. Epub 2013 Nov 6.

19.

A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes.

Cummins J, Casey PG, Joyce SA, Gahan CG.

PLoS One. 2013 Sep 12;8(9):e75437. doi: 10.1371/journal.pone.0075437. eCollection 2013.

20.

MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C.

Corr SC, Palsson-McDermott EM, Grishina I, Barry SP, Aviello G, Bernard NJ, Casey PG, Ward JB, Keely SJ, Dandekar S, Fallon PG, O'Neill LA.

Mucosal Immunol. 2014 Jan;7(1):57-67. doi: 10.1038/mi.2013.24. Epub 2013 Apr 24.

PMID:
23612054
22.

Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants.

Van Boeijen IK, Casey PG, Hill C, Moezelaar R, Zwietering MH, Gahan CG, Abee T.

Microb Pathog. 2013 Jun-Jul;59-60:48-51. doi: 10.1016/j.micpath.2013.04.007. Epub 2013 Apr 17.

PMID:
23603274
23.

In vivo activity of nisin A and nisin V against Listeria monocytogenes in mice.

Campion A, Casey PG, Field D, Cotter PD, Hill C, Ross RP.

BMC Microbiol. 2013 Feb 1;13:23. doi: 10.1186/1471-2180-13-23.

24.

A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice.

McLaughlin HP, Bahey-El-Din M, Casey PG, Hill C, Gahan CG.

J Med Microbiol. 2013 Feb;62(Pt 2):185-90. doi: 10.1099/jmm.0.049114-0. Epub 2012 Oct 25.

PMID:
23105022
25.

Residual antibiotics disrupt meat fermentation and increase risk of infection.

Kjeldgaard J, Cohn MT, Casey PG, Hill C, Ingmer H.

MBio. 2012 Aug 28;3(5):e00190-12. doi: 10.1128/mBio.00190-12. Print 2012.

26.

H5N1 moratorium: Missing the point.

Casey PG.

Bioeng Bugs. 2012 May-Jun;3(3):144. doi: 10.4161/bbug.20004. Epub 2012 May 1.

27.

HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe.

Heuston S, Begley M, Davey MS, Eberl M, Casey PG, Hill C, Gahan CG.

Microbiology. 2012 Jul;158(Pt 7):1684-93. doi: 10.1099/mic.0.056069-0. Epub 2012 Apr 13.

PMID:
22504435
28.

Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells.

Alemayehu D, Casey PG, McAuliffe O, Guinane CM, Martin JG, Shanahan F, Coffey A, Ross RP, Hill C.

MBio. 2012 Mar 6;3(2):e00029-12. doi: 10.1128/mBio.00029-12. Print 2012.

29.

Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota.

Riboulet-Bisson E, Sturme MH, Jeffery IB, O'Donnell MM, Neville BA, Forde BM, Claesson MJ, Harris H, Gardiner GE, Casey PG, Lawlor PG, O'Toole PW, Ross RP.

PLoS One. 2012;7(2):e31113. doi: 10.1371/journal.pone.0031113. Epub 2012 Feb 17.

30.

A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes.

McLaughlin HP, Xiao Q, Rea RB, Pi H, Casey PG, Darby T, Charbit A, Sleator RD, Joyce SA, Cowart RE, Hill C, Klebba PE, Gahan CG.

PLoS One. 2012;7(2):e30928. doi: 10.1371/journal.pone.0030928. Epub 2012 Feb 21.

31.

The Lantibiotic Lacticin 3147 Prevents Systemic Spread of Staphylococcus aureus in a Murine Infection Model.

Piper C, Casey PG, Hill C, Cotter PD, Ross RP.

Int J Microbiol. 2012;2012:806230. doi: 10.1155/2012/806230. Epub 2012 Jan 12.

32.

A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions.

O'Callaghan J, Reen FJ, Adams C, Casey PG, Gahan CG, O'Gara F.

Microbiology. 2012 Apr;158(Pt 4):1057-70. doi: 10.1099/mic.0.056127-0. Epub 2012 Jan 19.

PMID:
22262100
33.

Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes.

Dowd GC, Casey PG, Begley M, Hill C, Gahan CG.

FEMS Microbiol Lett. 2012 Feb;327(2):118-25. doi: 10.1111/j.1574-6968.2011.02472.x. Epub 2011 Dec 20.

34.

E. coli O104:H4: social media and the characterization of an emerging pathogen.

Casey PG, Hill C, Gahan CG.

Bioeng Bugs. 2011 Jul-Aug;2(4):189-93. doi: 10.4161/bbug.2.4.16961. Epub 2011 Jul 1.

PMID:
21715980
35.

Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor.

O'Connell Motherway M, Zomer A, Leahy SC, Reunanen J, Bottacini F, Claesson MJ, O'Brien F, Flynn K, Casey PG, Munoz JA, Kearney B, Houston AM, O'Mahony C, Higgins DG, Shanahan F, Palva A, de Vos WM, Fitzgerald GF, Ventura M, O'Toole PW, van Sinderen D.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11217-22. doi: 10.1073/pnas.1105380108. Epub 2011 Jun 20.

36.

Factors affecting survival of Listeria monocytogenes and Listeria innocua in soil samples.

McLaughlin HP, Casey PG, Cotter J, Gahan CG, Hill C.

Arch Microbiol. 2011 Nov;193(11):775-85. doi: 10.1007/s00203-011-0716-7. Epub 2011 May 25.

PMID:
21611773
37.

The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice.

Fenton M, Casey PG, Hill C, Gahan CG, Ross RP, McAuliffe O, O'Mahony J, Maher F, Coffey A.

Bioeng Bugs. 2010 Nov-Dec;1(6):404-7. doi: 10.4161/bbug.1.6.13422.

38.

Efficacy of a Lactococcus lactis ΔpyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes.

Bahey-El-Din M, Casey PG, Griffin BT, Gahan CG.

Bioeng Bugs. 2010 Jan-Feb;1(1):66-74. doi: 10.4161/bbug.1.1.10284.

39.

Fate and efficacy of lacticin 3147-producing Lactococcus lactis in the mammalian gastrointestinal tract.

Dobson A, Crispie F, Rea MC, O'Sullivan O, Casey PG, Lawlor PG, Cotter PD, Ross P, Gardiner GE, Hill C.

FEMS Microbiol Ecol. 2011 Jun;76(3):602-14. doi: 10.1111/j.1574-6941.2011.01069.x. Epub 2011 Mar 7.

40.
41.

Expression of two Listeria monocytogenes antigens (P60 and LLO) in Lactococcus lactis and examination for use as live vaccine vectors.

Bahey-El-Din M, Casey PG, Griffin BT, Gahan CG.

J Med Microbiol. 2010 Aug;59(Pt 8):904-12. doi: 10.1099/jmm.0.018770-0. Epub 2010 May 20.

PMID:
20488938
42.

Specific osmolyte transporters mediate bile tolerance in Listeria monocytogenes.

Watson D, Sleator RD, Casey PG, Hill C, Gahan CG.

Infect Immun. 2009 Nov;77(11):4895-904. doi: 10.1128/IAI.00153-09. Epub 2009 Sep 8.

43.

Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels.

Fang F, Li Y, Bumann M, Raftis EJ, Casey PG, Cooney JC, Walsh MA, O'Toole PW.

J Bacteriol. 2009 Sep;191(18):5743-57. doi: 10.1128/JB.00506-09. Epub 2009 Jul 10.

44.

Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: in vitro and in murine models of intestinal disease.

Gardiner GE, O'Flaherty S, Casey PG, Weber A, McDonald TL, Cronin M, Hill C, Ross RP, Gahan CG, Shanahan F.

FEMS Immunol Med Microbiol. 2009 Apr;55(3):404-13. doi: 10.1111/j.1574-695X.2009.00539.x. Epub 2009 Feb 11.

45.

AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes.

Riedel CU, Monk IR, Casey PG, Waidmann MS, Gahan CG, Hill C.

Mol Microbiol. 2009 Mar;71(5):1177-89. doi: 10.1111/j.1365-2958.2008.06589.x. Epub 2009 Jan 19.

46.

Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes.

Cotter PD, Draper LA, Lawton EM, Daly KM, Groeger DS, Casey PG, Ross RP, Hill C.

PLoS Pathog. 2008 Sep 12;4(9):e1000144. doi: 10.1371/journal.ppat.1000144.

47.

Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection.

Begley M, Bron PA, Heuston S, Casey PG, Englert N, Wiesner J, Jomaa H, Gahan CG, Hill C.

Infect Immun. 2008 Nov;76(11):5392-401. doi: 10.1128/IAI.01376-07. Epub 2008 Sep 2.

48.

Lactococcus lactis-expressing listeriolysin O (LLO) provides protection and specific CD8(+) T cells against Listeria monocytogenes in the murine infection model.

Bahey-El-Din M, Casey PG, Griffin BT, Gahan CG.

Vaccine. 2008 Sep 26;26(41):5304-14. doi: 10.1016/j.vaccine.2008.07.047. Epub 2008 Aug 6.

PMID:
18691625
49.

Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector.

Monk IR, Casey PG, Cronin M, Gahan CG, Hill C.

BMC Microbiol. 2008 Jun 13;8:96. doi: 10.1186/1471-2180-8-96.

50.

Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation.

Mulcahy H, O'Callaghan J, O'Grady EP, Maciá MD, Borrell N, Gómez C, Casey PG, Hill C, Adams C, Gahan CG, Oliver A, O'Gara F.

Infect Immun. 2008 Feb;76(2):632-8. Epub 2007 Nov 19.

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