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Items: 22


Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by BDNF.

Cases S, Saavedra A, Tyebji S, Giralt A, Alberch J, Pérez-Navarro E.

Mol Cell Neurosci. 2018 Jan;86:41-49. doi: 10.1016/j.mcn.2017.11.003. Epub 2017 Nov 6.


Chelerythrine promotes Ca2+-dependent calpain activation in neuronal cells in a PKC-independent manner.

Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E.

Biochim Biophys Acta Gen Subj. 2017 Apr;1861(4):922-935. doi: 10.1016/j.bbagen.2017.01.021. Epub 2017 Jan 24.


Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.

Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV Jr.

Aging (Albany NY). 2012 Jan;4(1):13-27.


1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R.

Bioorg Med Chem Lett. 2011 Feb 1;21(3):983-8. doi: 10.1016/j.bmcl.2010.12.042. Epub 2010 Dec 13.


Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer.

Purcell JW, Davis J, Reddy M, Martin S, Samayoa K, Vo H, Thomsen K, Bean P, Kuo WL, Ziyad S, Billig J, Feiler HS, Gray JW, Wood KW, Cases S.

Clin Cancer Res. 2010 Jan 15;16(2):566-76. doi: 10.1158/1078-0432.CCR-09-1498. Epub 2010 Jan 12.


P311 functions in an alternative pathway of lipid accumulation that is induced by retinoic acid.

Leung JK, Cases S, Vu TH.

J Cell Sci. 2008 Aug 15;121(Pt 16):2751-8. doi: 10.1242/jcs.027151. Epub 2008 Jul 29.


LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA).

Chan LC, Peters W, Xu Y, Chun J, Farese RV Jr, Cases S.

J Leukoc Biol. 2007 Nov;82(5):1193-200. Epub 2007 Aug 20.


Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues.

Cases S, Zhou P, Shillingford JM, Wiseman BS, Fish JD, Angle CS, Hennighausen L, Werb Z, Farese RV Jr.

Development. 2004 Jul;131(13):3047-55. Epub 2004 May 26.


Triglyceride accumulation protects against fatty acid-induced lipotoxicity.

Listenberger LL, Han X, Lewis SE, Cases S, Farese RV Jr, Ory DS, Schaffer JE.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3077-82. Epub 2003 Mar 10.


Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase.

Yen CL, Stone SJ, Cases S, Zhou P, Farese RV Jr.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8512-7. Epub 2002 Jun 19.


Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.

Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV Jr.

J Biol Chem. 2001 Oct 19;276(42):38870-6. Epub 2001 Jul 31.


Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase.

Farese RV Jr, Cases S, Smith SJ.

Curr Opin Lipidol. 2000 Jun;11(3):229-34. Review.


Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat.

Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, Tow B, Sanan DA, Raber J, Eckel RH, Farese RV Jr.

Nat Genet. 2000 May;25(1):87-90.


Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development.

Terasawa Y, Cases SJ, Wong JS, Jamil H, Jothi S, Traber MG, Packer L, Gordon DA, Hamilton RL, Farese RV Jr.

J Lipid Res. 1999 Nov;40(11):1967-77.


Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis.

Cases S, Smith SJ, Zheng YW, Myers HM, Lear SR, Sande E, Novak S, Collins C, Welch CB, Lusis AJ, Erickson SK, Farese RV Jr.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13018-23.


ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

Cases S, Novak S, Zheng YW, Myers HM, Lear SR, Sande E, Welch CB, Lusis AJ, Spencer TA, Krause BR, Erickson SK, Farese RV Jr.

J Biol Chem. 1998 Oct 9;273(41):26755-64.


Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation.

Meiner VL, Welch CL, Cases S, Myers HM, Sande E, Lusis AJ, Farese RV Jr.

J Biol Chem. 1998 Jan 9;273(2):1064-9.


Transcription of unr (upstream of N-ras) down-modulates N-ras expression in vivo.

Boussadia O, Amiot F, Cases S, Triqueneaux G, Jacquemin-Sablon H, Dautry F.

FEBS Lett. 1997 Dec 22;420(1):20-4.


Mice heterozygous for a deletion of the tumor necrosis factor-alpha and lymphotoxin-alpha genes: biological importance of a nonlinear response of tumor necrosis factor-alpha to gene dosage.

Amiot F, Boussadia O, Cases S, Fitting C, Lebastard M, Cavaillon JM, Milon G, Dautry F.

Eur J Immunol. 1997 Apr;27(4):1035-42.


Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.

Meiner VL, Cases S, Myers HM, Sande ER, Bellosta S, Schambelan M, Pitas RE, McGuire J, Herz J, Farese RV Jr.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14041-6.


A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice.

Farese RV Jr, Cases S, Ruland SL, Kayden HJ, Wong JS, Young SG, Hamilton RL.

J Lipid Res. 1996 Feb;37(2):347-60.


Inactivation of the murine N-ras gene by gene targeting.

Cases S, Dautry F.

Oncogene. 1992 Dec;7(12):2525-8.


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