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Items: 1 to 50 of 58

1.

Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow.

Pioli PD, Casero D, Montecino-Rodriguez E, Morrison SL, Dorshkind K.

Immunity. 2019 Aug 20;51(2):351-366.e6. doi: 10.1016/j.immuni.2019.06.006. Epub 2019 Jul 11.

PMID:
31303400
2.

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vázquez-Baeza Y, White RA 3rd; IBDMDB Investigators, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, McGovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C.

Nature. 2019 May;569(7758):655-662. doi: 10.1038/s41586-019-1237-9. Epub 2019 May 29.

3.

Lymphoid-Biased Hematopoietic Stem Cells Are Maintained with Age and Efficiently Generate Lymphoid Progeny.

Montecino-Rodriguez E, Kong Y, Casero D, Rouault A, Dorshkind K, Pioli PD.

Stem Cell Reports. 2019 Mar 5;12(3):584-596. doi: 10.1016/j.stemcr.2019.01.016. Epub 2019 Feb 21.

4.

The Placental Transcriptome in Late Gestational Hypoxia Resulting in Murine Intrauterine Growth Restriction Parallels Increased Risk of Adult Cardiometabolic Disease.

Chu A, Casero D, Thamotharan S, Wadehra M, Cosi A, Devaskar SU.

Sci Rep. 2019 Feb 4;9(1):1243. doi: 10.1038/s41598-018-37627-y.

5.

Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells.

Montel-Hagen A, Seet CS, Li S, Chick B, Zhu Y, Chang P, Tsai S, Sun V, Lopez S, Chen HC, He C, Chin CJ, Casero D, Crooks GM.

Cell Stem Cell. 2019 Mar 7;24(3):376-389.e8. doi: 10.1016/j.stem.2018.12.011. Epub 2019 Jan 17.

6.

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells.

Chang YL, Rossetti M, Vlamakis H, Casero D, Sunga G, Harre N, Miller S, Humphries R, Stappenbeck T, Simpson KW, Sartor RB, Wu G, Lewis J, Bushman F, McGovern DPB, Salzman N, Borneman J, Xavier R, Huttenhower C, Braun J.

Mucosal Immunol. 2019 Mar;12(2):457-467. doi: 10.1038/s41385-018-0022-7. Epub 2018 Apr 25.

7.

Differential Expression of PU.1 and Key T Lineage Transcription Factors Distinguishes Fetal and Adult T Cell Development.

Montecino-Rodriguez E, Casero D, Fice M, Le J, Dorshkind K.

J Immunol. 2018 Mar 15;200(6):2046-2056. doi: 10.4049/jimmunol.1701336. Epub 2018 Feb 7.

8.

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA.

Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P.

Nat Med. 2018 Mar;24(3):304-312. doi: 10.1038/nm.4479. Epub 2018 Feb 12.

9.

Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells.

Chin CJ, Li S, Corselli M, Casero D, Zhu Y, He CB, Hardy R, Péault B, Crooks GM.

Stem Cell Reports. 2018 Feb 13;10(2):436-446. doi: 10.1016/j.stemcr.2017.12.005. Epub 2018 Jan 4.

10.

Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome.

Casero D, Gill K, Sridharan V, Koturbash I, Nelson G, Hauer-Jensen M, Boerma M, Braun J, Cheema AK.

Microbiome. 2017 Aug 18;5(1):105. doi: 10.1186/s40168-017-0325-z.

11.

The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia.

Fernando TR, Contreras JR, Zampini M, Rodriguez-Malave NI, Alberti MO, Anguiano J, Tran TM, Palanichamy JK, Gajeton J, Ung NM, Aros CJ, Waters EV, Casero D, Basso G, Pigazzi M, Rao DS.

Mol Cancer. 2017 Jul 19;16(1):126. doi: 10.1186/s12943-017-0692-x.

12.

Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency.

Williams CJ, Chu A, Jefferson WN, Casero D, Sudhakar D, Khurana N, Hogue CP, Aryasomayajula C, Patel P, Sullivan P, Padilla-Banks E, Mohandessi S, Janzen C, Wadehra M.

J Pathol. 2017 Jun;242(2):246-259. doi: 10.1002/path.4893. Epub 2017 May 3.

13.

The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation.

Ha VL, Luong A, Li F, Casero D, Malvar J, Kim YM, Bhatia R, Crooks GM, Parekh C.

Leukemia. 2017 Nov;31(11):2503-2514. doi: 10.1038/leu.2017.70. Epub 2017 Feb 24.

14.

Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development.

Montecino-Rodriguez E, Fice M, Casero D, Berent-Maoz B, Barber CL, Dorshkind K.

Immunity. 2016 Sep 20;45(3):527-539. doi: 10.1016/j.immuni.2016.07.012. Epub 2016 Aug 23.

15.

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.

Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P.

Nature. 2016 Jun 2;534(7605):124-8. doi: 10.1038/nature17674. Epub 2016 May 11.

16.

Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications.

Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, Ballinari D, Ciomei M, Texido G, Degrassi A, Avanzi N, Amboldi N, Saccardo MB, Casero D, Orsini P, Bandiera T, Mologni L, Anderson D, Wei G, Harris J, Vernier JM, Li G, Felder E, Donati D, Isacchi A, Pesenti E, Magnaghi P, Galvani A.

Mol Cancer Ther. 2016 Apr;15(4):628-39. doi: 10.1158/1535-7163.MCT-15-0758. Epub 2016 Mar 3.

17.

Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors.

Chin CJ, Cooper AR, Lill GR, Evseenko D, Zhu Y, He CB, Casero D, Pellegrini M, Kohn DB, Crooks GM.

Stem Cells. 2016 May;34(5):1239-50. doi: 10.1002/stem.2351. Epub 2016 Mar 28.

18.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ.

Cell. 2015 Dec 17;163(7):1716-29. doi: 10.1016/j.cell.2015.11.045. Epub 2015 Dec 10.

19.

Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages.

Casero D, Sandoval S, Seet CS, Scholes J, Zhu Y, Ha VL, Luong A, Parekh C, Crooks GM.

Nat Immunol. 2015 Dec;16(12):1282-91. doi: 10.1038/ni.3299. Epub 2015 Oct 26.

20.

Convergent BCL6 and lncRNA promoters demarcate the major breakpoint region for BCL6 translocations.

Lu Z, Pannunzio NR, Greisman HA, Casero D, Parekh C, Lieber MR.

Blood. 2015 Oct 1;126(14):1730-1. doi: 10.1182/blood-2015-07-657999. Epub 2015 Aug 14. No abstract available.

21.

The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2).

Berent-Maoz B, Montecino-Rodriguez E, Fice M, Casero D, Seet CS, Crooks GM, Lowry W, Dorshkind K.

PLoS One. 2015 May 1;10(5):e0125414. doi: 10.1371/journal.pone.0125414. eCollection 2015.

22.

MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1.

Contreras JR, Palanichamy JK, Tran TM, Fernando TR, Rodriguez-Malave NI, Goswami N, Arboleda VA, Casero D, Rao DS.

Oncotarget. 2015 May 10;6(13):11023-37.

23.

Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders.

Brasca MG, Gnocchi P, Nesi M, Amboldi N, Avanzi N, Bertrand J, Bindi S, Canevari G, Casero D, Ciomei M, Colombo N, Cribioli S, Fachin G, Felder ER, Galvani A, Isacchi A, Motto I, Panzeri A, Donati D.

Bioorg Med Chem. 2015 May 15;23(10):2387-407. doi: 10.1016/j.bmc.2015.03.059. Epub 2015 Mar 28.

PMID:
25882525
24.

LncRNA Expression Discriminates Karyotype and Predicts Survival in B-Lymphoblastic Leukemia.

Fernando TR, Rodriguez-Malave NI, Waters EV, Yan W, Casero D, Basso G, Pigazzi M, Rao DS.

Mol Cancer Res. 2015 May;13(5):839-51. doi: 10.1158/1541-7786.MCR-15-0006-T. Epub 2015 Feb 13.

25.

Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors.

Brasca MG, Nesi M, Avanzi N, Ballinari D, Bandiera T, Bertrand J, Bindi S, Canevari G, Carenzi D, Casero D, Ceriani L, Ciomei M, Cirla A, Colombo M, Cribioli S, Cristiani C, Della Vedova F, Fachin G, Fasolini M, Felder ER, Galvani A, Isacchi A, Mirizzi D, Motto I, Panzeri A, Pesenti E, Vianello P, Gnocchi P, Donati D.

Bioorg Med Chem. 2014 Sep 1;22(17):4998-5012. doi: 10.1016/j.bmc.2014.06.025. Epub 2014 Jun 21.

PMID:
25009002
26.

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

Ardini E, Bosotti R, Borgia AL, De Ponti C, Somaschini A, Cammarota R, Amboldi N, Raddrizzani L, Milani A, Magnaghi P, Ballinari D, Casero D, Gasparri F, Banfi P, Avanzi N, Saccardo MB, Alzani R, Bandiera T, Felder E, Donati D, Pesenti E, Sartore-Bianchi A, Gambacorta M, Pierotti MA, Siena S, Veronese S, Galvani A, Isacchi A.

Mol Oncol. 2014 Dec;8(8):1495-507. doi: 10.1016/j.molonc.2014.06.001. Epub 2014 Jun 12.

27.

Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control.

Ramundo S, Casero D, Mühlhaus T, Hemme D, Sommer F, Crèvecoeur M, Rahire M, Schroda M, Rusch J, Goodenough U, Pellegrini M, Perez-Perez ME, Crespo JL, Schaad O, Civic N, Rochaix JD.

Plant Cell. 2014 May;26(5):2201-2222. Epub 2014 May 30.

28.

Phosphoprotein SAK1 is a regulator of acclimation to singlet oxygen in Chlamydomonas reinhardtii.

Wakao S, Chin BL, Ledford HK, Dent RM, Casero D, Pellegrini M, Merchant SS, Niyogi KK.

Elife. 2014 May 23;3:e02286. doi: 10.7554/eLife.02286.

29.

Nitrogen-Sparing Mechanisms in Chlamydomonas Affect the Transcriptome, the Proteome, and Photosynthetic Metabolism.

Schmollinger S, Mühlhaus T, Boyle NR, Blaby IK, Casero D, Mettler T, Moseley JL, Kropat J, Sommer F, Strenkert D, Hemme D, Pellegrini M, Grossman AR, Stitt M, Schroda M, Merchant SS.

Plant Cell. 2014 Apr;26(4):1410-1435. Epub 2014 Apr 18.

30.

The path to triacylglyceride obesity in the sta6 strain of Chlamydomonas reinhardtii.

Goodenough U, Blaby I, Casero D, Gallaher SD, Goodson C, Johnson S, Lee JH, Merchant SS, Pellegrini M, Roth R, Rusch J, Singh M, Umen JG, Weiss TL, Wulan T.

Eukaryot Cell. 2014 May;13(5):591-613. doi: 10.1128/EC.00013-14. Epub 2014 Feb 28.

31.

Systems-level analysis of nitrogen starvation-induced modifications of carbon metabolism in a Chlamydomonas reinhardtii starchless mutant.

Blaby IK, Glaesener AG, Mettler T, Fitz-Gibbon ST, Gallaher SD, Liu B, Boyle NR, Kropat J, Stitt M, Johnson S, Benning C, Pellegrini M, Casero D, Merchant SS.

Plant Cell. 2013 Nov;25(11):4305-23. doi: 10.1105/tpc.113.117580. Epub 2013 Nov 26.

32.

Copper response regulator1-dependent and -independent responses of the Chlamydomonas reinhardtii transcriptome to dark anoxia.

Hemschemeier A, Casero D, Liu B, Benning C, Pellegrini M, Happe T, Merchant SS.

Plant Cell. 2013 Sep;25(9):3186-211. doi: 10.1105/tpc.113.115741. Epub 2013 Sep 6.

33.

Remodeling of membrane lipids in iron-starved Chlamydomonas.

Urzica EI, Vieler A, Hong-Hermesdorf A, Page MD, Casero D, Gallaher SD, Kropat J, Pellegrini M, Benning C, Merchant SS.

J Biol Chem. 2013 Oct 18;288(42):30246-58. doi: 10.1074/jbc.M113.490425. Epub 2013 Aug 27.

34.

Hypoxic survival requires a 2-on-2 hemoglobin in a process involving nitric oxide.

Hemschemeier A, Düner M, Casero D, Merchant SS, Winkler M, Happe T.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10854-9. doi: 10.1073/pnas.1302592110. Epub 2013 Jun 10.

35.

Zinc deficiency impacts CO2 assimilation and disrupts copper homeostasis in Chlamydomonas reinhardtii.

Malasarn D, Kropat J, Hsieh SI, Finazzi G, Casero D, Loo JA, Pellegrini M, Wollman FA, Merchant SS.

J Biol Chem. 2013 Apr 12;288(15):10672-83. doi: 10.1074/jbc.M113.455105. Epub 2013 Feb 25.

36.

A large-scale zebrafish gene knockout resource for the genome-wide study of gene function.

Varshney GK, Lu J, Gildea DE, Huang H, Pei W, Yang Z, Huang SC, Schoenfeld D, Pho NH, Casero D, Hirase T, Mosbrook-Davis D, Zhang S, Jao LE, Zhang B, Woods IG, Zimmerman S, Schier AF, Wolfsberg TG, Pellegrini M, Burgess SM, Lin S.

Genome Res. 2013 Apr;23(4):727-35. doi: 10.1101/gr.151464.112. Epub 2013 Feb 4.

37.

Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival.

Duanmu D, Casero D, Dent RM, Gallaher S, Yang W, Rockwell NC, Martin SS, Pellegrini M, Niyogi KK, Merchant SS, Grossman AR, Lagarias JC.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3621-6. doi: 10.1073/pnas.1222375110. Epub 2013 Jan 23.

38.

Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.

Daniels-Wells TR, Helguera G, Rodríguez JA, Leoh LS, Erb MA, Diamante G, Casero D, Pellegrini M, Martínez-Maza O, Penichet ML.

Toxicol In Vitro. 2013 Feb;27(1):220-31. doi: 10.1016/j.tiv.2012.10.006. Epub 2012 Oct 17.

39.

The proteome of copper, iron, zinc, and manganese micronutrient deficiency in Chlamydomonas reinhardtii.

Hsieh SI, Castruita M, Malasarn D, Urzica E, Erde J, Page MD, Yamasaki H, Casero D, Pellegrini M, Merchant SS, Loo JA.

Mol Cell Proteomics. 2013 Jan;12(1):65-86. doi: 10.1074/mcp.M112.021840. Epub 2012 Oct 13.

40.

Systems and trans-system level analysis identifies conserved iron deficiency responses in the plant lineage.

Urzica EI, Casero D, Yamasaki H, Hsieh SI, Adler LN, Karpowicz SJ, Blaby-Haas CE, Clarke SG, Loo JA, Pellegrini M, Merchant SS.

Plant Cell. 2012 Oct;24(10):3921-48. doi: 10.1105/tpc.112.102491. Epub 2012 Oct 5. Erratum in: Plant Cell. 2019 Jun;31(6):1385.

41.

Activation of the carbon concentrating mechanism by CO2 deprivation coincides with massive transcriptional restructuring in Chlamydomonas reinhardtii.

Brueggeman AJ, Gangadharaiah DS, Cserhati MF, Casero D, Weeks DP, Ladunga I.

Plant Cell. 2012 May;24(5):1860-75. doi: 10.1105/tpc.111.093435. Epub 2012 May 25. Erratum in: Plant Cell. 2012 Aug;24(8):3483.

42.

Transcriptome-wide changes in Chlamydomonas reinhardtii gene expression regulated by carbon dioxide and the CO2-concentrating mechanism regulator CIA5/CCM1.

Fang W, Si Y, Douglass S, Casero D, Merchant SS, Pellegrini M, Ladunga I, Liu P, Spalding MH.

Plant Cell. 2012 May;24(5):1876-93. doi: 10.1105/tpc.112.097949. Epub 2012 May 25.

43.

SINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii.

Fischer BB, Ledford HK, Wakao S, Huang SG, Casero D, Pellegrini M, Merchant SS, Koller A, Eggen RI, Niyogi KK.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1302-11. doi: 10.1073/pnas.1116843109. Epub 2012 Apr 23.

44.

Three acyltransferases and nitrogen-responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas.

Boyle NR, Page MD, Liu B, Blaby IK, Casero D, Kropat J, Cokus SJ, Hong-Hermesdorf A, Shaw J, Karpowicz SJ, Gallaher SD, Johnson S, Benning C, Pellegrini M, Grossman A, Merchant SS.

J Biol Chem. 2012 May 4;287(19):15811-25. doi: 10.1074/jbc.M111.334052. Epub 2012 Mar 8.

45.

Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase.

Urzica EI, Adler LN, Page MD, Linster CL, Arbing MA, Casero D, Pellegrini M, Merchant SS, Clarke SG.

J Biol Chem. 2012 Apr 20;287(17):14234-45. doi: 10.1074/jbc.M112.341982. Epub 2012 Mar 5.

46.

Transcriptome sequencing identifies SPL7-regulated copper acquisition genes FRO4/FRO5 and the copper dependence of iron homeostasis in Arabidopsis.

Bernal M, Casero D, Singh V, Wilson GT, Grande A, Yang H, Dodani SC, Pellegrini M, Huijser P, Connolly EL, Merchant SS, Krämer U.

Plant Cell. 2012 Feb;24(2):738-61. doi: 10.1105/tpc.111.090431. Epub 2012 Feb 28.

47.

Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells.

Rodríguez JA, Luria-Pérez R, López-Valdés HE, Casero D, Daniels TR, Patel S, Avila D, Leuchter R, So S, Ortiz-Sánchez E, Bonavida B, Martínez-Maza O, Charles AC, Pellegrini M, Helguera G, Penichet ML.

Leuk Lymphoma. 2011 Nov;52(11):2169-78. doi: 10.3109/10428194.2011.596964. Epub 2011 Aug 28.

48.

Algal Functional Annotation Tool: a web-based analysis suite to functionally interpret large gene lists using integrated annotation and expression data.

Lopez D, Casero D, Cokus SJ, Merchant SS, Pellegrini M.

BMC Bioinformatics. 2011 Jul 12;12:282. doi: 10.1186/1471-2105-12-282.

49.

Systems biology approach in Chlamydomonas reveals connections between copper nutrition and multiple metabolic steps.

Castruita M, Casero D, Karpowicz SJ, Kropat J, Vieler A, Hsieh SI, Yan W, Cokus S, Loo JA, Benning C, Pellegrini M, Merchant SS.

Plant Cell. 2011 Apr;23(4):1273-92. doi: 10.1105/tpc.111.084400. Epub 2011 Apr 15.

50.

A revised mineral nutrient supplement increases biomass and growth rate in Chlamydomonas reinhardtii.

Kropat J, Hong-Hermesdorf A, Casero D, Ent P, Castruita M, Pellegrini M, Merchant SS, Malasarn D.

Plant J. 2011 Jun;66(5):770-80. doi: 10.1111/j.1365-313X.2011.04537.x. Epub 2011 Mar 21.

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