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FGF21 gene therapy as treatment for obesity and insulin resistance.

Jimenez V, Jambrina C, Casana E, Sacristan V, Muñoz S, Darriba S, Rodó J, Mallol C, Garcia M, León X, Marcó S, Ribera A, Elias I, Casellas A, Grass I, Elias G, Ferré T, Motas S, Franckhauser S, Mulero F, Navarro M, Haurigot V, Ruberte J, Bosch F.

EMBO Mol Med. 2018 Aug;10(8). pii: e8791. doi: 10.15252/emmm.201708791.


Hepatitis C prevalence among the migrant population in Spain: A systematic review and meta-analysis.

Lazarus JV, Bromberg DJ, Del Amo J, Norgaard O, García-Samaniego J, Casellas A, Calleja JL, Requena-Méndez A.

Enferm Infecc Microbiol Clin. 2018 May 30. pii: S0213-005X(18)30171-X. doi: 10.1016/j.eimc.2018.04.002. [Epub ahead of print] English, Spanish.


Awareness of cervical cancer and willingness to be vaccinated against human papillomavirus in Mozambican adolescent girls.

Bardají A, Mindu C, Augusto OJ, Casellas A, Cambaco O, Simbine E, Matsinhe G, Macete E, Menéndez C, Sevene E, Munguambe K.

Papillomavirus Res. 2018 Jun;5:156-162. doi: 10.1016/j.pvr.2018.04.004. Epub 2018 Apr 14.


[Community-acquired pneumonia in patients with chronic obstructive pulmonary disease treated with inhaled corticosteroids or other bronchodilators. Study PNEUMOCORT].

Morros R, Vedia C, Giner-Soriano M, Casellas A, Amado E, Baena JM; en representación de los investigadores del proyecto PNEUMOCORT.

Aten Primaria. 2018 Apr 13. pii: S0212-6567(17)30358-X. doi: 10.1016/j.aprim.2018.02.007. [Epub ahead of print] Spanish.


BCG vaccination in southern rural Mozambique: an overview of coverage and its determinants based on data from the demographic and health surveillance system in the district of Manhiça.

Marbán-Castro E, Sacoor C, Nhacolo A, Augusto O, Jamisse E, López-Varela E, Casellas A, Aponte JJ, Bassat Q, Sigauque B, Macete E, Garcia-Basteiro AL.

BMC Pediatr. 2018 Feb 13;18(1):56. doi: 10.1186/s12887-018-1003-4.


Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure.

Valmaseda A, Macete E, Nhabomba A, Guinovart C, Aide P, Bardají A, Bassat Q, Nhampossa T, Maculuve S, Casellas A, Quintó L, Sanz S, Jiménez A, Feng G, Langer C, Reiling L, Reddy KS, Pandey A, Chitnis CE, Chauhan VS, Aguilar R, Aponte JJ, Dobaño C, Beeson JG, Gaur D, Menéndez C, Alonso PL, Mayor A.

Clin Infect Dis. 2018 Feb 1;66(4):586-593. doi: 10.1093/cid/cix837.


What to expect and when: benznidazole toxicity in chronic Chagas' disease treatment.

Aldasoro E, Posada E, Requena-Méndez A, Calvo-Cano A, Serret N, Casellas A, Sanz S, Soy D, Pinazo MJ, Gascon J.

J Antimicrob Chemother. 2018 Apr 1;73(4):1060-1067. doi: 10.1093/jac/dkx516.


Interferon-γ-Inducible Protein 10 (IP-10) as a Screening Tool to Optimize Human Immunodeficiency Virus RNA Monitoring in Resource-Limited Settings.

Pastor L, Casellas A, Rupérez M, Carrillo J, Maculuve S, Jairoce C, Paredes R, Blanco J, Naniche D.

Clin Infect Dis. 2017 Oct 30;65(10):1670-1675. doi: 10.1093/cid/cix600.


IP-10 Levels as an Accurate Screening Tool to Detect Acute HIV Infection in Resource-Limited Settings.

Pastor L, Casellas A, Carrillo J, Alonso S, Parker E, Fuente-Soro L, Jairoce C, Mandomando I, Blanco J, Naniche D.

Sci Rep. 2017 Aug 14;7(1):8104. doi: 10.1038/s41598-017-08218-0.


Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.

Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Tomassoni Ardori F, Resch W, Stavreva D, Nelson S, McAndrew M, Casellas A, Finn E, Gregory C, St Hilaire BG, Johnson SM, Dubois W, Cosma MP, Batchelor E, Levens D, Phair RD, Misteli T, Tessarollo L, Hager G, Lakadamyali M, Liu Z, Floer M, Shroff H, Aiden EL, Casellas R.

Mol Cell. 2017 Aug 17;67(4):566-578.e10. doi: 10.1016/j.molcel.2017.07.013. Epub 2017 Aug 10.


AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

Mallol C, Casana E, Jimenez V, Casellas A, Haurigot V, Jambrina C, Sacristan V, Morró M, Agudo J, Vilà L, Bosch F.

Mol Metab. 2017 May 17;6(7):664-680. doi: 10.1016/j.molmet.2017.05.007. eCollection 2017 Jul.


Host age and expression of genes involved in red blood cell invasion in Plasmodium falciparum field isolates.

Valmaseda A, Bassat Q, Aide P, Cisteró P, Jiménez A, Casellas A, Machevo S, Aguilar R, Sigaúque B, Chauhan VS, Langer C, Beeson J, Chitnis C, Alonso PL, Gaur D, Mayor A.

Sci Rep. 2017 Jul 5;7(1):4717. doi: 10.1038/s41598-017-05025-5.


Continuous determination of blood glucose in children admitted with malaria in a rural hospital in Mozambique.

Madrid L, Sitoe A, Varo R, Nhampossa T, Lanaspa M, Nhama A, Acácio S, Riaño I, Casellas A, Bassat Q.

Malar J. 2017 May 2;16(1):184. doi: 10.1186/s12936-017-1840-x.


AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance.

Vilà L, Roca C, Elias I, Casellas A, Lage R, Franckhauser S, Bosch F.

Mol Ther Methods Clin Dev. 2016 Nov 16;5:16072. eCollection 2016.


Erratum to: Poor tuberculosis treatment outcomes in Southern Mozambique (2011-2012).

García-Basteiro AL, Respeito D, Augusto OJ, López-Varela E, Sacoor C, Sequera VG, Casellas A, Bassat Q, Manhiça I, Macete E, Cobelens F, Alonso PL.

BMC Infect Dis. 2016 Oct 25;16(1):603. No abstract available.


ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.

Elias I, Ferré T, Vilà L, Muñoz S, Casellas A, Garcia M, Molas M, Agudo J, Roca C, Ruberte J, Bosch F, Franckhauser S.

Diabetes. 2016 Aug;65(8):2139-50. doi: 10.2337/db16-0040. Epub 2016 May 3.


Poor tuberculosis treatment outcomes in Southern Mozambique (2011-2012).

García-Basteiro AL, Respeito D, Augusto OJ, López-Varela E, Sacoor C, Sequera VG, Casellas A, Bassat Q, Manhiça I, Macete E, Cobelens F, Alonso PL.

BMC Infect Dis. 2016 May 20;16:214. doi: 10.1186/s12879-016-1534-y. Erratum in: BMC Infect Dis. 2016 Oct 25;16(1):603.


Drug Therapy for Rate and Rhythm Control in Nonvalvular Atrial Fibrillation: A Cross-sectional Study With Electronic Health Records in a Primary Care Cohort.

Giner-Soriano M, Roso-Llorach A, Vedia Urgell C, Casellas A, Ferreira-González I, Capellà D, Morros R.

Clin Ther. 2016 Apr;38(4):863-73. doi: 10.1016/j.clinthera.2016.02.002. Epub 2016 Feb 28.


Chronic Kidney Disease and Diabetic Retinopathy in Patients with Type 2 Diabetes.

Rodríguez-Poncelas A, Mundet-Tudurí X, Miravet-Jiménez S, Casellas A, Barrot-De la Puente JF, Franch-Nadal J, Coll-de Tuero G.

PLoS One. 2016 Feb 17;11(2):e0149448. doi: 10.1371/journal.pone.0149448. eCollection 2016.


Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.

Teichenne J, Morró M, Casellas A, Jimenez V, Tellez N, Leger A, Bosch F, Ayuso E.

PLoS One. 2015 Dec 21;10(12):e0145116. doi: 10.1371/journal.pone.0145116. eCollection 2015.


Direct medical costs attributable to type 2 diabetes mellitus: a population-based study in Catalonia, Spain.

Mata-Cases M, Casajuana M, Franch-Nadal J, Casellas A, Castell C, Vinagre I, Mauricio D, Bolíbar B.

Eur J Health Econ. 2016 Nov;17(8):1001-1010. Epub 2015 Nov 5.


Origin of malaria cases: a 7-year audit of global trends in indigenous and imported cases in relation to malaria elimination.

Velarde-Rodríguez M, Van den Bergh R, Fergus C, Casellas A, Sanz S, Cibulskis R, Ramsay AR, Bissell K, Zachariah R.

Glob Health Action. 2015 Oct 7;8:29133. doi: 10.3402/gha.v8.29133. eCollection 2015.


Older type 2 diabetic patients are more likely to achieve glycaemic and cardiovascular risk factors targets than younger patients: analysis of a primary care database.

Barrot-de la Puente J, Mata-Cases M, Franch-Nadal J, Mundet-Tudurí X, Casellas A, Fernandez-Real JM, Mauricio D.

Int J Clin Pract. 2015 Dec;69(12):1486-95. doi: 10.1111/ijcp.12741. Epub 2015 Sep 30.


Prevalence of diabetic retinopathy in individuals with type 2 diabetes who had recorded diabetic retinopathy from retinal photographs in Catalonia (Spain).

Rodriguez-Poncelas A, Miravet-Jiménez S, Casellas A, Barrot-De La Puente JF, Franch-Nadal J, López-Simarro F, Mata-Cases M, Mundet-Tudurí X.

Br J Ophthalmol. 2015 Dec;99(12):1628-33. doi: 10.1136/bjophthalmol-2015-306683. Epub 2015 Jun 18.


Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage.

Casellas A, Mallol C, Salavert A, Jimenez V, Garcia M, Agudo J, Obach M, Haurigot V, Vilà L, Molas M, Lage R, Morró M, Casana E, Ruberte J, Bosch F.

J Biol Chem. 2015 Jul 3;290(27):16772-85. doi: 10.1074/jbc.M115.642041. Epub 2015 May 13.


Differences in the Cardiometabolic Control in Type 2 Diabetes according to Gender and the Presence of Cardiovascular Disease: Results from the eControl Study.

Franch-Nadal J, Mata-Cases M, Vinagre I, Patitucci F, Hermosilla E, Casellas A, Bolivar B, Mauricio D.

Int J Endocrinol. 2014;2014:131709. doi: 10.1155/2014/131709. Epub 2014 Sep 21.


AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease.

Vilà L, Elias I, Roca C, Ribera A, Ferré T, Casellas A, Lage R, Franckhauser S, Bosch F.

Mol Ther Methods Clin Dev. 2014 Oct 1;1:14039. doi: 10.1038/mtm.2014.39. eCollection 2014.


Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice.

Anguela XM, Tafuro S, Roca C, Callejas D, Agudo J, Obach M, Ribera A, Ruzo A, Mann CJ, Casellas A, Bosch F.

Diabetes. 2013 Feb;62(2):551-60. doi: 10.2337/db11-1776. Epub 2012 Oct 25.


Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass.

Agudo J, Ayuso E, Jimenez V, Casellas A, Mallol C, Salavert A, Tafuro S, Obach M, Ruzo A, Moya M, Pujol A, Bosch F.

Diabetes. 2012 Nov;61(11):2851-61. doi: 10.2337/db12-0134. Epub 2012 Sep 6.


Altered glucose-stimulated insulin secretion in a mouse line with activated polyamine catabolism.

Cerrada-Gimenez M, Tusa M, Casellas A, Pirinen E, Moya M, Bosch F, Alhonen L.

Transgenic Res. 2012 Aug;21(4):843-53. doi: 10.1007/s11248-011-9579-6. Epub 2011 Dec 18.


In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9.

Jimenez V, Ayuso E, Mallol C, Agudo J, Casellas A, Obach M, Muñoz S, Salavert A, Bosch F.

Diabetologia. 2011 May;54(5):1075-86. doi: 10.1007/s00125-011-2070-3. Epub 2011 Feb 11.


IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

Agudo J, Ayuso E, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F.

Diabetologia. 2008 Oct;51(10):1862-72. doi: 10.1007/s00125-008-1087-8. Epub 2008 Jul 29.


Expression of IGF-I in pancreatic islets prevents lymphocytic infiltration and protects mice from type 1 diabetes.

Casellas A, Salavert A, Agudo J, Ayuso E, Jimenez V, Moya M, Muñoz S, Franckhauser S, Bosch F.

Diabetes. 2006 Dec;55(12):3246-55.


Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

Ruberte J, Ayuso E, Navarro M, Carretero A, Nacher V, Haurigot V, George M, Llombart C, Casellas A, Costa C, Bosch A, Bosch F.

J Clin Invest. 2004 Apr;113(8):1149-57.


Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

George M, Ayuso E, Casellas A, Costa C, Devedjian JC, Bosch F.

J Clin Invest. 2002 May;109(9):1153-63.


Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.

Franckhauser S, Muñoz S, Pujol A, Casellas A, Riu E, Otaegui P, Su B, Bosch F.

Diabetes. 2002 Mar;51(3):624-30.


Transgenic mice overexpressing alpha2A-adrenoceptors in pancreatic beta-cells show altered regulation of glucose homeostasis.

Devedjian JC, Pujol A, Cayla C, George M, Casellas A, Paris H, Bosch F.

Diabetologia. 2000 Jul;43(7):899-906.


Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta.

Boscá L, Bodelón OG, Hortelano S, Casellas A, Bosch F.

Gene Ther. 2000 May;7(10):817-25.


Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

Devedjian JC, George M, Casellas A, Pujol A, Visa J, Pelegrín M, Gros L, Bosch F.

J Clin Invest. 2000 Mar;105(6):731-40.


Pruritus in chronic hepatitis C: association with high serum bile acids, advanced pathology, and bile duct abnormalities.

Lebovics E, Seif F, Kim D, Elhosseiny A, Dworkin BM, Casellas A, Clark S, Rosenthal WS.

Dig Dis Sci. 1997 May;42(5):1094-9.


The breakthrough phenomenon during alpha-interferon therapy of chronic hepatitis C: incidence, management, and outcome.

Lebovics E, Lantin J, Chaurushia G, Dworkin BM, Casellas A, Rosenthal WS.

Am J Gastroenterol. 1995 Jun;90(6):951-4.


Open label study of long-term effectiveness of cisapride in patients with idiopathic gastroparesis.

Dworkin BM, Rosenthal WS, Casellas AR, Girolomo R, Lebovics E, Freeman S, Clark SB.

Dig Dis Sci. 1994 Jul;39(7):1395-8.


The safety and efficacy of gi endoscopy in patients with acute-leukemia - a review of 27 cases.

Dworkin B, Winzelberg N, Ahmed T, Lebovics E, Heier S, Feldman E, Stein B, Casellas A, Arlin Z.

Int J Oncol. 1992 Sep;1(4):439-42.


Increased superoxide production by polymorphonuclear leukocytes in systemic lupus erythematosus.

Casellas AM, Prat A, Llera A, Manni J, Boveris A, Sarano JF.

Clin Exp Rheumatol. 1991 Sep-Oct;9(5):511-4.


Upper gastrointestinal bleeding following open heart surgery. Predominant finding of aggressive duodenal ulcer disease.

Lebovics E, Lee SS, Dworkin BM, Heier SK, Casellas A, Reed G, Rosenthal WS.

Dig Dis Sci. 1991 Jun;36(6):757-60.


Inhibition by opioids of phagocytosis in peritoneal macrophages.

Casellas AM, Guardiola H, Renaud FL.

Neuropeptides. 1991 Jan;18(1):35-40.


[Erythrocyte CR1 receptor reactivity in patients with systemic lupus erythematosus].

Said PB, Sarano J, Manni JA, Casellas AM.

Medicina (B Aires). 1990;50(1):21-4. Spanish.


[Neutrophil-dependent inflammatory reactions in systemic lupus erythematosus].

Sarano JF, Said P, Llera A, Prat A, Boveris A, Casellas A, Manni JA.

Medicina (B Aires). 1989;49(2):113-8. Spanish.


Naloxone-reversible inhibition by opiates of phagocytosis in Tetrahymena thermophila and mouse macrophages.

Casellas AM, De Jesus S, Guardiola H, Renaud FL.

P R Health Sci J. 1988 Aug;7(2):103-5. No abstract available.


Oxygen-derived radicals from Trypanosoma cruzi-stimulated human neutrophils.

Docampo R, Casellas AM, Madeira ED, Cardoni RL, Moreno SN, Mason RP.

FEBS Lett. 1983 May 2;155(1):25-30.

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