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Interim results of a prospective, randomized, open-label, Phase 3 study of the long-term safety and efficacy of lasmiditan for acute treatment of migraine (the GLADIATOR study).

Brandes JL, Klise S, Krege JH, Case M, Khanna R, Vasudeva R, Raskin J, Pearlman EM, Kudrow D.

Cephalalgia. 2019 Aug 21:333102419864132. doi: 10.1177/0333102419864132. [Epub ahead of print]


Comparison of Survival Rates After a Combination of Local Treatment and Systemic Therapy vs Systemic Therapy Alone for Treatment of Stage IV Non-Small Cell Lung Cancer.

Uhlig J, Case MD, Blasberg JD, Boffa DJ, Chiang A, Gettinger SN, Kim HS.

JAMA Netw Open. 2019 Aug 2;2(8):e199702. doi: 10.1001/jamanetworkopen.2019.9702.


Effect of a rescue or recurrence dose of lasmiditan on efficacy and safety in the acute treatment of migraine: findings from the phase 3 trials (SAMURAI and SPARTAN).

Loo LS, Plato BM, Turner IM, Case MG, Raskin J, Dowsett SA, Krege JH.

BMC Neurol. 2019 Aug 13;19(1):191. doi: 10.1186/s12883-019-1420-5.


Magnetic resonance imaging measures of brain atrophy from the EXPEDITION3 trial in mild Alzheimer's disease.

Schwarz AJ, Sundell KL, Charil A, Case MG, Jaeger RK, Scott D, Bracoud L, Oh J, Suhy J, Pontecorvo MJ, Dickerson BC, Siemers ER.

Alzheimers Dement (N Y). 2019 Jul 30;5:328-337. doi: 10.1016/j.trci.2019.05.007. eCollection 2019.


Severe drought limits trees in a semi-arid savanna.

Case MF, Wigley-Coetsee C, Nzima N, Scogings PF, Staver AC.

Ecology. 2019 Jul 24:e02842. doi: 10.1002/ecy.2842. [Epub ahead of print]


Phase 3 randomized, placebo-controlled, double-blind study of lasmiditan for acute treatment of migraine.

Goadsby PJ, Wietecha LA, Dennehy EB, Kuca B, Case MG, Aurora SK, Gaul C.

Brain. 2019 Jul 1;142(7):1894-1904. doi: 10.1093/brain/awz134.


Physical Functioning Among Patients Aging With Human Immunodeficiency Virus (HIV) Versus HIV Uninfected: Feasibility of Using the Short Physical Performance Battery in Clinical Care of People Living With HIV Aged 50 or Older.

Crane HM, Miller ME, Pierce J, Willig AL, Case ML, Wilkin AM, Brown S, Asirot MG, Fredericksen RJ, Saag MS, Landay AL, High KP.

Open Forum Infect Dis. 2019 Mar 11;6(3):ofz038. doi: 10.1093/ofid/ofz038. eCollection 2019 Mar.


SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain.

Sinclair PB, Ryan S, Bashton M, Hollern S, Hanna R, Case M, Schwalbe EC, Schwab CJ, Cranston RE, Young BD, Irving JAE, Vora AJ, Moorman AV, Harrison CJ.

Leukemia. 2019 Aug;33(8):1881-1894. doi: 10.1038/s41375-019-0412-1. Epub 2019 Feb 28.


A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.

Rangwala SM, D'Aquino K, Zhang YM, Bader L, Edwards W, Zheng S, Eckardt A, Lacombe A, Pick R, Moreno V, Kang L, Jian W, Arnoult E, Case M, Jenkinson C, Chi E, Swanson RV, Kievit P, Grove K, Macielag M, Erion MD, SinhaRoy R, Leonard JN.

Cell Metab. 2019 Apr 2;29(4):837-843.e5. doi: 10.1016/j.cmet.2019.01.017. Epub 2019 Feb 14.


Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.

Matheson EC, Thomas H, Case M, Blair H, Jackson RK, Masic D, Veal G, Halsey C, Newell DR, Vormoor J, Irving JAE.

Haematologica. 2019 Sep;104(9):1804-1811. doi: 10.3324/haematol.2017.185975. Epub 2019 Jan 17.


Central pharmacodynamic activity of solanezumab in mild Alzheimer's disease dementia.

Willis BA, Sundell K, Lachno DR, Ferguson-Sells LR, Case MG, Holdridge K, DeMattos RB, Raskin J, Siemers ER, Dean RA.

Alzheimers Dement (N Y). 2018 Nov 9;4:652-660. doi: 10.1016/j.trci.2018.10.001. eCollection 2018.


Graph theory analysis reveals how sickle cell disease impacts neural networks of patients with more severe disease.

Case M, Shirinpour S, Vijayakumar V, Zhang H, Datta Y, Nelson S, Pergami P, Darbari DS, Gupta K, He B.

Neuroimage Clin. 2019;21:101599. doi: 10.1016/j.nicl.2018.11.009. Epub 2018 Nov 14.


Climate change impacts on the distribution of the allergenic plant, common ragweed (Ambrosia artemisiifolia) in the eastern United States.

Case MJ, Stinson KA.

PLoS One. 2018 Oct 31;13(10):e0205677. doi: 10.1371/journal.pone.0205677. eCollection 2018.


Quantitation of intact monoclonal antibody in biological samples: comparison of different data processing strategies.

Qiu X, Kang L, Case M, Weng N, Jian W.

Bioanalysis. 2018 Jul 1;10(13):1055-1067. doi: 10.4155/bio-2018-0016. Epub 2018 Jul 4.


Soil texture mediates tree responses to rainfall intensity in African savannas.

Case MF, Staver AC.

New Phytol. 2018 Sep;219(4):1363-1372. doi: 10.1111/nph.15254. Epub 2018 Jun 4.


Delayed-Start Analyses in the Phase 3 Solanezumab EXPEDITION3 Study in Mild Alzheimer's Disease.

Liu-Seifert H, Case MG, Andersen SW, Holdridge KC, Aisen PS, Kollack-Walker S, Siemers E.

J Prev Alzheimers Dis. 2018;5(1):8-14. doi: 10.14283/jpad.2018.1.


Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.

Honig LS, Vellas B, Woodward M, Boada M, Bullock R, Borrie M, Hager K, Andreasen N, Scarpini E, Liu-Seifert H, Case M, Dean RA, Hake A, Sundell K, Poole Hoffmann V, Carlson C, Khanna R, Mintun M, DeMattos R, Selzler KJ, Siemers E.

N Engl J Med. 2018 Jan 25;378(4):321-330. doi: 10.1056/NEJMoa1705971.


Increased theta band EEG power in sickle cell disease patients.

Case M, Shirinpour S, Zhang H, Datta YH, Nelson SC, Sadak KT, Gupta K, He B.

J Pain Res. 2017 Dec 27;11:67-76. doi: 10.2147/JPR.S145581. eCollection 2018.


Heme oxygenase activity increases after exercise in healthy volunteers.

Ghio AJ, Case MW, Soukup JM.

Free Radic Res. 2018 Feb;52(2):267-272. doi: 10.1080/10715762.2018.1428965. Epub 2018 Feb 6.


Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients.

Mirowsky JE, Carraway MS, Dhingra R, Tong H, Neas L, Diaz-Sanchez D, Cascio W, Case M, Crooks J, Hauser ER, Elaine Dowdy Z, Kraus WE, Devlin RB.

Environ Health. 2017 Nov 21;16(1):126. doi: 10.1186/s12940-017-0335-0.


Quantifying and Characterizing Tonic Thermal Pain Across Subjects From EEG Data Using Random Forest Models.

Vijayakumar V, Case M, Shirinpour S, He B.

IEEE Trans Biomed Eng. 2017 Dec;64(12):2988-2996. doi: 10.1109/TBME.2017.2756870. Epub 2017 Sep 25.


You don't have to know the answers to write poetry.

Case M.

Nurs Stand. 2017 Jun 21;31(43):18-20. doi: 10.7748/ns.31.43.18.s21.


PirB regulates asymmetries in hippocampal circuitry.

Ukai H, Kawahara A, Hirayama K, Case MJ, Aino S, Miyabe M, Wakita K, Oogi R, Kasayuki M, Kawashima S, Sugimoto S, Chikamatsu K, Nitta N, Koga T, Shigemoto R, Takai T, Ito I.

PLoS One. 2017 Jun 8;12(6):e0179377. doi: 10.1371/journal.pone.0179377. eCollection 2017.


Statistical properties of continuous composite scales and implications for drug development.

Liu-Seifert H, Andersen S, Case M, Sparks J, Holdridge KC, Wessels AM, Hendrix S, Aisen P, Siemers E.

J Biopharm Stat. 2017;27(6):1104-1114. doi: 10.1080/10543406.2017.1315819. Epub 2017 Apr 27.


Characterization of functional brain activity and connectivity using EEG and fMRI in patients with sickle cell disease.

Case M, Zhang H, Mundahl J, Datta Y, Nelson S, Gupta K, He B.

Neuroimage Clin. 2016 Dec 26;14:1-17. doi: 10.1016/j.nicl.2016.12.024. eCollection 2017.


lac-1 and lag-1 with ras-1 affect aging and the biological clock in Neurospora crassa.

Brunson JK, Griffith J, Bowles D, Case ME, Arnold J.

Ecol Evol. 2016 Oct 24;6(23):8341-8351. doi: 10.1002/ece3.2554. eCollection 2016 Dec.


A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia.

Vormoor B, Veal GJ, Griffin MJ, Boddy AV, Irving J, Minto L, Case M, Banerji U, Swales KE, Tall JR, Moore AS, Toguchi M, Acton G, Dyer K, Schwab C, Harrison CJ, Grainger JD, Lancaster D, Kearns P, Hargrave D, Vormoor J.

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26351. Epub 2016 Dec 1.


Integrating mechanistic and empirical model projections to assess climate impacts on tree species distributions in northwestern North America.

Case MJ, Lawler JJ.

Glob Chang Biol. 2017 May;23(5):2005-2015. doi: 10.1111/gcb.13570. Epub 2016 Dec 18.


The effect of extremity strength training on fibromyalgia symptoms and disease impact in an existing multidisciplinary treatment program.

Kas T, Colby M, Case M, Vaughn D.

J Bodyw Mov Ther. 2016 Oct;20(4):774-783. doi: 10.1016/j.jbmt.2016.01.005. Epub 2016 Jan 29.


Culturally Grounded Stress Reduction and Suicide Prevention for African American Adolescents.

Robinson WL, Case MH, Whipple CR, Gooden AS, Lopez-Tamayo R, Lambert SF, Jason LA.

Pract Innov (Wash D C). 2016 Jun;1(2):117-128.


Pediatric Emergency Department Return: A Literature Review of Risk Factors and Interventions.

Tran QK, Bayram JD, Boonyasai RT, Case MA, Connor C, Doggett D, Fawole OA, Ijagbemi OM, Levin S, Wu AW, Pham JC.

Pediatr Emerg Care. 2016 Aug;32(8):570-7. doi: 10.1097/PEC.0000000000000876. Review.


Amyloid-related imaging abnormalities from trials of solanezumab for Alzheimer's disease.

Carlson C, Siemers E, Hake A, Case M, Hayduk R, Suhy J, Oh J, Barakos J.

Alzheimers Dement (Amst). 2016 Mar 2;2:75-85. doi: 10.1016/j.dadm.2016.02.004. eCollection 2016.


BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance.

Weiland J, Pal D, Case M, Irving J, Ponthan F, Koschmieder S, Heidenreich O, von Stackelberg A, Eckert C, Vormoor J, Elder A.

Leukemia. 2016 Sep;30(9):1920-3. doi: 10.1038/leu.2016.64. Epub 2016 Mar 17. No abstract available.


Reducing Stress and Preventing Anxiety in African American Adolescents: A Culturally- Grounded Approach.

Robinson WL, Droege JR, Case MH, Jason LA.

Glob J Community Psychol Pract. 2015 Oct;6(2). pii: Epub 2015 Oct 15.


Structure and dynamics of the phytoplankton community within a maturation pond in a semiarid region.

Pastich EA, Gavazza S, Casé MC, Florencio L, Kato MT.

Braz J Biol. 2016 Feb;76(1):144-53. doi: 10.1590/1519-6984.15214. Epub 2016 Jan 22.


Florbetapir F18 PET Amyloid Neuroimaging and Characteristics in Patients With Mild and Moderate Alzheimer Dementia.

Degenhardt EK, Witte MM, Case MG, Yu P, Henley DB, Hochstetler HM, D'Souza DN, Trzepacz PT.

Psychosomatics. 2016 Mar-Apr;57(2):208-16. doi: 10.1016/j.psym.2015.12.002. Epub 2015 Dec 3.


Longitudinal Trajectories of Clinical Decline in Amyloid Positive and Negative Populations.

Trzepacz PT, Hochstetler H, Wang S, Yu P, Case M, Henley DB, Degenhardt E, Leoutsakos JM, Lyketsos CG.

J Prev Alzheimers Dis. 2016;3(2):92-100. doi: 10.14283/jpad.2016.90.


Empirically Defining Trajectories of Late-Life Cognitive and Functional Decline.

Hochstetler H, Trzepacz PT, Wang S, Yu P, Case M, Henley DB, Degenhardt E, Leoutsakos JM, Lyketsos CG.

J Alzheimers Dis. 2016;50(1):271-82. doi: 10.3233/JAD-150563.


Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition.

Nicholson L, Evans CA, Matheson E, Minto L, Keilty C, Sanichar M, Case M, Schwab C, Williamson D, Rainer J, Harrison CJ, Kofler R, Hall AG, Redfern CP, Whetton AD, Irving JA.

Br J Haematol. 2015 Nov;171(4):595-605. doi: 10.1111/bjh.13647. Epub 2015 Aug 27.


Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients.

Siemers ER, Sundell KL, Carlson C, Case M, Sethuraman G, Liu-Seifert H, Dowsett SA, Pontecorvo MJ, Dean RA, Demattos R.

Alzheimers Dement. 2016 Feb;12(2):110-120. doi: 10.1016/j.jalz.2015.06.1893. Epub 2015 Aug 1.


Electronic devices and applications to track physical activity--reply.

Case MA, Volpp KG, Patel MS.

JAMA. 2015 May 26;313(20):2080. doi: 10.1001/jama.2015.3880. No abstract available.


Dietary Supplementation with Olive Oil or Fish Oil and Vascular Effects of Concentrated Ambient Particulate Matter Exposure in Human Volunteers.

Tong H, Rappold AG, Caughey M, Hinderliter AL, Bassett M, Montilla T, Case MW, Berntsen J, Bromberg PA, Cascio WE, Diaz-Sanchez D, Devlin RB, Samet JM.

Environ Health Perspect. 2015 Nov;123(11):1173-9. doi: 10.1289/ehp.1408988. Epub 2015 May 1.


Florbetapir positron emission tomography and cerebrospinal fluid biomarkers.

Hake A, Trzepacz PT, Wang S, Yu P, Case M, Hochstetler H, Witte MM, Degenhardt EK, Dean RA; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2015 Aug;11(8):986-93. doi: 10.1016/j.jalz.2015.03.002. Epub 2015 Apr 24.


Accuracy of smartphone applications and wearable devices for tracking physical activity data.

Case MA, Burwick HA, Volpp KG, Patel MS.

JAMA. 2015 Feb 10;313(6):625-6. doi: 10.1001/jama.2014.17841. No abstract available.


The aging biological clock in Neurospora crassa.

Case ME, Griffith J, Dong W, Tigner IL, Gaines K, Jiang JC, Jazwinski SM, Arnold J; Georgia Centenarian Study.

Ecol Evol. 2014 Sep;4(17):3494-507. doi: 10.1002/ece3.1202. Epub 2014 Aug 22.


Interaction effects of temperature and ozone on lung function and markers of systemic inflammation, coagulation, and fibrinolysis: a crossover study of healthy young volunteers.

Kahle JJ, Neas LM, Devlin RB, Case MW, Schmitt MT, Madden MC, Diaz-Sanchez D.

Environ Health Perspect. 2015 Apr;123(4):310-6. doi: 10.1289/ehp.1307986. Epub 2014 Dec 16.


Distinguishing accidental from inflicted head trauma at autopsy.

Case ME.

Pediatr Radiol. 2014 Dec;44 Suppl 4:S632-40. doi: 10.1007/s00247-014-3061-6. Epub 2014 Dec 14.


Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.

Irving J, Matheson E, Minto L, Blair H, Case M, Halsey C, Swidenbank I, Ponthan F, Kirschner-Schwabe R, Groeneveld-Krentz S, Hof J, Allan J, Harrison C, Vormoor J, von Stackelberg A, Eckert C.

Blood. 2014 Nov 27;124(23):3420-30. doi: 10.1182/blood-2014-04-531871. Epub 2014 Sep 24.


Diesel exhaust modulates ozone-induced lung function decrements in healthy human volunteers.

Madden MC, Stevens T, Case M, Schmitt M, Diaz-Sanchez D, Bassett M, Montilla TS, Berntsen J, Devlin RB.

Part Fibre Toxicol. 2014 Sep 2;11:37. doi: 10.1186/s12989-014-0037-5.


Incidence of tardive dyskinesia in older adult patients treated with olanzapine or conventional antipsychotics.

Kinon BJ, Kollack-Walker S, Jeste D, Gupta S, Chen L, Case M, Chen J, Stauffer V.

J Geriatr Psychiatry Neurol. 2015 Mar;28(1):67-79. doi: 10.1177/0891988714541867. Epub 2014 Jul 9.

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