Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 264

1.

p13CMFA: Parsimonious 13C metabolic flux analysis.

Foguet C, Jayaraman A, Marin S, Selivanov VA, Moreno P, Messeguer R, de Atauri P, Cascante M.

PLoS Comput Biol. 2019 Sep 6;15(9):e1007310. doi: 10.1371/journal.pcbi.1007310. eCollection 2019 Sep.

2.

Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction.

Nukala SB, Regazzoni L, Aldini G, Zodda E, Tura-Ceide O, Mills NL, Cascante M, Carini M, D'Amato A.

Hypertension. 2019 Oct;74(4):947-956. doi: 10.1161/HYPERTENSIONAHA.119.13472. Epub 2019 Aug 26.

PMID:
31446798
3.

Stoichiometric gene-to-reaction associations enhance model-driven analysis performance: Metabolic response to chronic exposure to Aldrin in prostate cancer.

Marín de Mas I, Torrents L, Bedia C, Nielsen LK, Cascante M, Tauler R.

BMC Genomics. 2019 Aug 15;20(1):652. doi: 10.1186/s12864-019-5979-4.

4.

Synthesis and Antiproliferative Activity of Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives.

Alho DPS, Salvador JAR, Cascante M, Marin S.

Molecules. 2019 Aug 14;24(16). pii: E2938. doi: 10.3390/molecules24162938.

5.

Metabolic Plasticity and Epithelial-Mesenchymal Transition.

Thomson TM, Balcells C, Cascante M.

J Clin Med. 2019 Jul 3;8(7). pii: E967. doi: 10.3390/jcm8070967. Review.

6.

Author Correction: Forearc carbon sink reduces long-term volatile recycling into the mantle.

Barry PH, de Moor JM, Giovannelli D, Schrenk M, Hummer DR, Lopez T, Pratt CA, Segura YA, Battaglia A, Beaudry P, Bini G, Cascante M, d'Errico G, di Carlo M, Fattorini D, Fullerton K, Gazel E, González G, Halldórsson SA, Iacovino K, Kulongoski JT, Manini E, Martínez M, Miller H, Nakagawa M, Ono S, Patwardhan S, Ramírez CJ, Regoli F, Smedile F, Turner S, Vetriani C, Yücel M, Ballentine CJ, Fischer TP, Hilton DR, Lloyd KG.

Nature. 2019 Jul;571(7765):E7. doi: 10.1038/s41586-019-1298-9.

PMID:
31263274
7.

Forearc carbon sink reduces long-term volatile recycling into the mantle.

Barry PH, de Moor JM, Giovannelli D, Schrenk M, Hummer DR, Lopez T, Pratt CA, Segura YA, Battaglia A, Beaudry P, Bini G, Cascante M, d'Errico G, di Carlo M, Fattorini D, Fullerton K, Gazel E, González G, Halldórsson SA, Iacovino K, Kulongoski JT, Manini E, Martínez M, Miller H, Nakagawa M, Ono S, Patwardhan S, Ramírez CJ, Regoli F, Smedile F, Turner S, Vetriani C, Yücel M, Ballentine CJ, Fischer TP, Hilton DR, Lloyd KG.

Nature. 2019 Apr;568(7753):487-492. doi: 10.1038/s41586-019-1131-5. Epub 2019 Apr 24. Erratum in: Nature. 2019 Jul;571(7765):E7.

PMID:
31019327
8.

Interoperable and scalable data analysis with microservices: applications in metabolomics.

Emami Khoonsari P, Moreno P, Bergmann S, Burman J, Capuccini M, Carone M, Cascante M, de Atauri P, Foguet C, Gonzalez-Beltran AN, Hankemeier T, Haug K, He S, Herman S, Johnson D, Kale N, Larsson A, Neumann S, Peters K, Pireddu L, Rocca-Serra P, Roger P, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Schober D, Selivanov V, Thévenot EA, van Vliet M, Zanetti G, Steinbeck C, Kultima K, Spjuth O.

Bioinformatics. 2019 Oct 1;35(19):3752-3760. doi: 10.1093/bioinformatics/btz160.

9.

Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.

Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C, Esteller M.

JCI Insight. 2019 Mar 7;5. pii: 125888. doi: 10.1172/jci.insight.125888.

10.

Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives.

Alho DPS, Salvador JAR, Cascante M, Marin S.

Molecules. 2019 Feb 20;24(4). pii: E766. doi: 10.3390/molecules24040766.

11.

New world goat populations are a genetically diverse reservoir for future use.

Paim TDP, Faria DA, Hay EH, McManus C, Lanari MR, Esquivel LC, Cascante MI, Alfaro EJ, Mendez A, Faco O, Silva KM, Mezzadra CA, Mariante A, Paiva SR, Blackburn HD.

Sci Rep. 2019 Feb 6;9(1):1476. doi: 10.1038/s41598-019-38812-3.

12.

Metabolic Alterations in Cardiopulmonary Vascular Dysfunction.

Smolders VF, Zodda E, Quax PHA, Carini M, Barberà JA, Thomson TM, Tura-Ceide O, Cascante M.

Front Mol Biosci. 2019 Jan 22;5:120. doi: 10.3389/fmolb.2018.00120. eCollection 2018. Review.

13.

PhenoMeNal: processing and analysis of metabolomics data in the cloud.

Peters K, Bradbury J, Bergmann S, Capuccini M, Cascante M, de Atauri P, Ebbels TMD, Foguet C, Glen R, Gonzalez-Beltran A, Günther UL, Handakas E, Hankemeier T, Haug K, Herman S, Holub P, Izzo M, Jacob D, Johnson D, Jourdan F, Kale N, Karaman I, Khalili B, Emami Khonsari P, Kultima K, Lampa S, Larsson A, Ludwig C, Moreno P, Neumann S, Novella JA, O'Donovan C, Pearce JTM, Peluso A, Piras ME, Pireddu L, Reed MAC, Rocca-Serra P, Roger P, Rosato A, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Selivanov V, Spjuth O, Schober D, Thévenot EA, Tomasoni M, van Rijswijk M, van Vliet M, Viant MR, Weber RJM, Zanetti G, Steinbeck C.

Gigascience. 2019 Feb 1;8(2). pii: giy149. doi: 10.1093/gigascience/giy149.

14.

Tumor-associated metabolic and inflammatory responses in early stage non-small cell lung cancer: Local patterns and prognostic significance.

Millares L, Barreiro E, Cortes R, Martinez-Romero A, Balcells C, Cascante M, Enguita AB, Alvarez C, Rami-Porta R, Sánchez de Cos J, Seijo L, Monsó E; Grupo Colaborativo en Cáncer de Pulmón CIBERES- CIBERONC- SEPAR - Plataforma Biobanco Pulmonar.

Lung Cancer. 2018 Aug;122:124-130. doi: 10.1016/j.lungcan.2018.06.015. Epub 2018 Jun 10.

PMID:
30032820
15.

Synthesis, characterization and biological activity of new cyclometallated platinum(iv) complexes containing a para-tolyl ligand.

Solé M, Balcells C, Crespo M, Quirante J, Badia J, Baldomà L, Font-Bardia M, Cascante M.

Dalton Trans. 2018 Jul 10;47(27):8956-8971. doi: 10.1039/c8dt01124a.

PMID:
29922789
16.

Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).

Kirwan JA, Brennan L, Broadhurst D, Fiehn O, Cascante M, Dunn WB, Schmidt MA, Velagapudi V.

Clin Chem. 2018 Aug;64(8):1158-1182. doi: 10.1373/clinchem.2018.287045. Epub 2018 Jun 19. Review.

17.

From correlation to causation: analysis of metabolomics data using systems biology approaches.

Rosato A, Tenori L, Cascante M, De Atauri Carulla PR, Martins Dos Santos VAP, Saccenti E.

Metabolomics. 2018;14(4):37. doi: 10.1007/s11306-018-1335-y. Epub 2018 Feb 27. Review.

18.

Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations.

Jayaraman A, Kumar P, Marin S, de Atauri P, Mateo F, M Thomson T, J Centelles J, F Graham S, Cascante M.

PLoS One. 2018 Feb 21;13(2):e0192175. doi: 10.1371/journal.pone.0192175. eCollection 2018.

19.

Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients.

Tényi Á, Cano I, Marabita F, Kiani N, Kalko SG, Barreiro E, de Atauri P, Cascante M, Gomez-Cabrero D, Roca J.

J Transl Med. 2018 Feb 20;16(1):34. doi: 10.1186/s12967-018-1405-y.

20.

Model-driven discovery of long-chain fatty acid metabolic reprogramming in heterogeneous prostate cancer cells.

Marín de Mas I, Aguilar E, Zodda E, Balcells C, Marin S, Dallmann G, Thomson TM, Papp B, Cascante M.

PLoS Comput Biol. 2018 Jan 2;14(1):e1005914. doi: 10.1371/journal.pcbi.1005914. eCollection 2018 Jan.

21.

Instrumental drift removal in GC-MS data for breath analysis: the short-term and long-term temporal validation of putative biomarkers for COPD.

Rodríguez-Pérez R, Cortés R, Guamán A, Pardo A, Torralba Y, Gómez F, Roca J, Barberà JA, Cascante M, Marco S.

J Breath Res. 2018 Mar 14;12(3):036007. doi: 10.1088/1752-7163/aaa492.

22.

Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome.

Benito A, Polat IH, Noé V, Ciudad CJ, Marin S, Cascante M.

Oncotarget. 2017 Oct 7;8(63):106693-106706. doi: 10.18632/oncotarget.21601. eCollection 2017 Dec 5.

23.

The future of metabolomics in ELIXIR.

van Rijswijk M, Beirnaert C, Caron C, Cascante M, Dominguez V, Dunn WB, Ebbels TMD, Giacomoni F, Gonzalez-Beltran A, Hankemeier T, Haug K, Izquierdo-Garcia JL, Jimenez RC, Jourdan F, Kale N, Klapa MI, Kohlbacher O, Koort K, Kultima K, Le Corguillé G, Moreno P, Moschonas NK, Neumann S, O'Donovan C, Reczko M, Rocca-Serra P, Rosato A, Salek RM, Sansone SA, Satagopam V, Schober D, Shimmo R, Spicer RA, Spjuth O, Thévenot EA, Viant MR, Weber RJM, Willighagen EL, Zanetti G, Steinbeck C.

Version 2. F1000Res. 2017 Sep 6 [revised 2017 Jan 1];6. pii: ELIXIR-1649. doi: 10.12688/f1000research.12342.2. eCollection 2017.

24.

MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells.

Sánchez-Cid L, Pons M, Lozano JJ, Rubio N, Guerra-Rebollo M, Soriano A, Paris-Coderch L, Segura MF, Fueyo R, Arguimbau J, Zodda E, Bermudo R, Alonso I, Caparrós X, Cascante M, Rafii A, Kang Y, Martínez-Balbás M, Weiss SJ, Blanco J, Muñoz M, Fernández PL, Thomson TM.

Oncotarget. 2017 Sep 7;8(48):83384-83406. doi: 10.18632/oncotarget.20698. eCollection 2017 Oct 13.

25.

In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer.

Pey J, San José-Eneriz E, Ochoa MC, Apaolaza I, de Atauri P, Rubio A, Cendoya X, Miranda E, Garate L, Cascante M, Carracedo A, Agirre X, Prosper F, Planes FJ.

Sci Rep. 2017 Oct 30;7(1):14358. doi: 10.1038/s41598-017-14067-8.

26.

Synthesis, characterization and biological activity of new cyclometallated platinum(iv) iodido complexes.

Bauer E, Domingo X, Balcells C, Polat IH, Crespo M, Quirante J, Badía J, Baldomà L, Font-Bardia M, Cascante M.

Dalton Trans. 2017 Nov 7;46(43):14973-14987. doi: 10.1039/c7dt03448b.

PMID:
29048088
27.

De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition.

Tarrado-Castellarnau M, de Atauri P, Tarragó-Celada J, Perarnau J, Yuneva M, Thomson TM, Cascante M.

Mol Syst Biol. 2017 Oct 4;13(10):940. doi: 10.15252/msb.20167321.

28.

Induction of oxidative metabolism by the p38α/MK2 pathway.

Trempolec N, Muñoz JP, Slobodnyuk K, Marin S, Cascante M, Zorzano A, Nebreda AR.

Sci Rep. 2017 Sep 12;7(1):11367. doi: 10.1038/s41598-017-11309-7.

29.

Design, synthesis and biological evaluation of novel C-29 carbamate celastrol derivatives as potent and selective cytotoxic compounds.

Figueiredo SAC, Salvador JAR, Cortés R, Cascante M.

Eur J Med Chem. 2017 Oct 20;139:836-848. doi: 10.1016/j.ejmech.2017.08.058. Epub 2017 Aug 26.

PMID:
28865279
30.

Novel celastrol derivatives with improved selectivity and enhanced antitumour activity: Design, synthesis and biological evaluation.

Figueiredo SAC, Salvador JAR, Cortés R, Cascante M.

Eur J Med Chem. 2017 Sep 29;138:422-437. doi: 10.1016/j.ejmech.2017.06.029. Epub 2017 Jun 16.

PMID:
28688281
31.

Unveiling the Metabolic Changes on Muscle Cell Metabolism Underlying p-Phenylenediamine Toxicity.

Marín de Mas I, Marín S, Pachón G, Rodríguez-Prados JC, Vizán P, Centelles JJ, Tauler R, Azqueta A, Selivanov V, López de Ceraín A, Cascante M.

Front Mol Biosci. 2017 Mar 6;4:8. doi: 10.3389/fmolb.2017.00008. eCollection 2017.

32.

Combined Analysis of NMR and MS Spectra (CANMS).

Chong M, Jayaraman A, Marin S, Selivanov V, de Atauri Carulla PR, Tennant DA, Cascante M, Günther UL, Ludwig C.

Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4140-4144. doi: 10.1002/anie.201611634. Epub 2017 Mar 8.

PMID:
28272839
33.

MIDcor, an R-program for deciphering mass interferences in mass spectra of metabolites enriched in stable isotopes.

Selivanov VA, Benito A, Miranda A, Aguilar E, Polat IH, Centelles JJ, Jayaraman A, Lee PW, Marin S, Cascante M.

BMC Bioinformatics. 2017 Feb 3;18(1):88. doi: 10.1186/s12859-017-1513-3.

34.

Oncogenic regulation of tumor metabolic reprogramming.

Tarrado-Castellarnau M, de Atauri P, Cascante M.

Oncotarget. 2016 Sep 20;7(38):62726-62753. doi: 10.18632/oncotarget.10911. Review.

35.

Molecular mechanisms underlying COPD-muscle dysfunction unveiled through a systems medicine approach.

Marín de Mas I, Fanchon E, Papp B, Kalko S, Roca J, Cascante M.

Bioinformatics. 2017 Jan 1;33(1):95-103. doi: 10.1093/bioinformatics/btw566. Epub 2016 Oct 6.

36.

On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions.

Escolà A, Crespo M, López C, Quirante J, Jayaraman A, Polat IH, Badía J, Baldomà L, Cascante M.

Bioorg Med Chem. 2016 Nov 15;24(22):5804-5815. doi: 10.1016/j.bmc.2016.09.037. Epub 2016 Sep 15.

PMID:
27670096
37.

Metabolomics enables precision medicine: "A White Paper, Community Perspective".

Beger RD, Dunn W, Schmidt MA, Gross SS, Kirwan JA, Cascante M, Brennan L, Wishart DS, Oresic M, Hankemeier T, Broadhurst DI, Lane AN, Suhre K, Kastenmüller G, Sumner SJ, Thiele I, Fiehn O, Kaddurah-Daouk R; for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Society Initiative.

Metabolomics. 2016;12(10):149. Epub 2016 Sep 2.

38.

A key role for transketolase-like 1 in tumor metabolic reprogramming.

Diaz-Moralli S, Aguilar E, Marin S, Coy JF, Dewerchin M, Antoniewicz MR, Meca-Cortés O, Notebaert L, Ghesquière B, Eelen G, Thomson TM, Carmeliet P, Cascante M.

Oncotarget. 2016 Aug 9;7(32):51875-51897. doi: 10.18632/oncotarget.10429.

39.

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.

Cvijovic M, Höfer T, Aćimović J, Alberghina L, Almaas E, Besozzi D, Blomberg A, Bretschneider T, Cascante M, Collin O, de Atauri P, Depner C, Dickinson R, Dobrzynski M, Fleck C, Garcia-Ojalvo J, Gonze D, Hahn J, Hess HM, Hollmann S, Krantz M, Kummer U, Lundh T, Martial G, Dos Santos VM, Mauer-Oberthür A, Regierer B, Skene B, Stalidzans E, Stelling J, Teusink B, Workman CT, Hohmann S.

NPJ Syst Biol Appl. 2016 May 26;2:16011. doi: 10.1038/npjsba.2016.11. eCollection 2016.

40.

Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program.

Aguilar E, Marin de Mas I, Zodda E, Marin S, Morrish F, Selivanov V, Meca-Cortés Ó, Delowar H, Pons M, Izquierdo I, Celià-Terrassa T, de Atauri P, Centelles JJ, Hockenbery D, Thomson TM, Cascante M.

Stem Cells. 2016 May;34(5):1163-76. doi: 10.1002/stem.2286. Epub 2016 Feb 2.

41.

Restrictions in ATP diffusion within sarcomeres can provoke ATP-depleted zones impairing exercise capacity in chronic obstructive pulmonary disease.

Alekseev AE, Guzun R, Reyes S, Pison C, Schlattner U, Selivanov VA, Cascante M.

Biochim Biophys Acta. 2016 Oct;1860(10):2269-78. doi: 10.1016/j.bbagen.2016.04.018. Epub 2016 Apr 27.

PMID:
27130881
42.

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data.

Foguet C, Marin S, Selivanov VA, Fanchon E, Lee WN, Guinovart JJ, de Atauri P, Cascante M.

PLoS Comput Biol. 2016 Apr 28;12(4):e1004899. doi: 10.1371/journal.pcbi.1004899. eCollection 2016 Apr.

43.

Synthesis and anticancer activity of novel fluorinated asiatic acid derivatives.

Gonçalves BM, Salvador JA, Marín S, Cascante M.

Eur J Med Chem. 2016 May 23;114:101-17. doi: 10.1016/j.ejmech.2016.02.057. Epub 2016 Mar 22.

PMID:
26974379
44.

Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells.

Reyes-Zurita FJ, Rufino-Palomares EE, García-Salguero L, Peragón J, Medina PP, Parra A, Cascante M, Lupiáñez JA.

PLoS One. 2016 Jan 11;11(1):e0146178. doi: 10.1371/journal.pone.0146178. eCollection 2016.

45.

ChainRank, a chain prioritisation method for contextualisation of biological networks.

Tényi Á, de Atauri P, Gomez-Cabrero D, Cano I, Clarke K, Falciani F, Cascante M, Roca J, Maier D.

BMC Bioinformatics. 2016 Jan 5;17:17. doi: 10.1186/s12859-015-0864-x.

46.

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access.

Salek RM, Neumann S, Schober D, Hummel J, Billiau K, Kopka J, Correa E, Reijmers T, Rosato A, Tenori L, Turano P, Marin S, Deborde C, Jacob D, Rolin D, Dartigues B, Conesa P, Haug K, Rocca-Serra P, O'Hagan S, Hao J, van Vliet M, Sysi-Aho M, Ludwig C, Bouwman J, Cascante M, Ebbels T, Griffin JL, Moing A, Nikolski M, Oresic M, Sansone SA, Viant MR, Goodacre R, Günther UL, Hankemeier T, Luchinat C, Walther D, Steinbeck C.

Metabolomics. 2015;11(6):1587-1597. Epub 2015 May 26.

47.

Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition.

Tarrado-Castellarnau M, Cortés R, Zanuy M, Tarragó-Celada J, Polat IH, Hill R, Fan TW, Link W, Cascante M.

Pharmacol Res. 2015 Dec;102:218-34. doi: 10.1016/j.phrs.2015.09.009. Epub 2015 Nov 4.

48.

Neutral and ionic platinum compounds containing a cyclometallated chiral primary amine: synthesis, antitumor activity, DNA interaction and topoisomerase I-cathepsin B inhibition.

Albert J, Bosque R, Crespo M, Granell J, López C, Martín R, González A, Jayaraman A, Quirante J, Calvis C, Badía J, Baldomà L, Font-Bardia M, Cascante M, Messeguer R.

Dalton Trans. 2015 Aug 14;44(30):13602-14. doi: 10.1039/c5dt01713k.

PMID:
26140359
49.

Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes.

Binns M, de Atauri P, Vlysidis A, Cascante M, Theodoropoulos C.

BMC Bioinformatics. 2015 Feb 18;16:49. doi: 10.1186/s12859-015-0476-5.

50.

Cancer cell metabolism as new targets for novel designed therapies.

Marín de Mas I, Aguilar E, Jayaraman A, Polat IH, Martín-Bernabé A, Bharat R, Foguet C, Milà E, Papp B, Centelles JJ, Cascante M.

Future Med Chem. 2014;6(16):1791-810. Review.

PMID:
25574531

Supplemental Content

Loading ...
Support Center