Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 93


Cell Width Dictates Type VI Secretion Tail Length.

Santin YG, Doan T, Journet L, Cascales E.

Curr Biol. 2019 Nov 4;29(21):3707-3713.e3. doi: 10.1016/j.cub.2019.08.058. Epub 2019 Oct 17.


Structure and Activity of the Type VI Secretion System.

Cherrak Y, Flaugnatti N, Durand E, Journet L, Cascales E.

Microbiol Spectr. 2019 Jul;7(4). doi: 10.1128/microbiolspec.PSIB-0031-2019.


Role and Recruitment of the TagL Peptidoglycan-Binding Protein during Type VI Secretion System Biogenesis.

Santin YG, Camy CE, Zoued A, Doan T, Aschtgen MS, Cascales E.

J Bacteriol. 2019 May 22;201(12). pii: e00173-19. doi: 10.1128/JB.00173-19. Print 2019 Jun 15.


In situ and high-resolution cryo-EM structure of a bacterial type VI secretion system membrane complex.

Rapisarda C, Cherrak Y, Kooger R, Schmidt V, Pellarin R, Logger L, Cascales E, Pilhofer M, Durand E, Fronzes R.

EMBO J. 2019 May 15;38(10). pii: e100886. doi: 10.15252/embj.2018100886. Epub 2019 Mar 15.


Biogenesis and structure of a type VI secretion baseplate.

Cherrak Y, Rapisarda C, Pellarin R, Bouvier G, Bardiaux B, Allain F, Malosse C, Rey M, Chamot-Rooke J, Cascales E, Fronzes R, Durand E.

Nat Microbiol. 2018 Dec;3(12):1404-1416. doi: 10.1038/s41564-018-0260-1. Epub 2018 Oct 15.


In vivo TssA proximity labelling during type VI secretion biogenesis reveals TagA as a protein that stops and holds the sheath.

Santin YG, Doan T, Lebrun R, Espinosa L, Journet L, Cascales E.

Nat Microbiol. 2018 Nov;3(11):1304-1313. doi: 10.1038/s41564-018-0234-3. Epub 2018 Oct 1.


The gp27-like Hub of VgrG Serves as Adaptor to Promote Hcp Tube Assembly.

Renault MG, Zamarreno Beas J, Douzi B, Chabalier M, Zoued A, Brunet YR, Cambillau C, Journet L, Cascales E.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3143-3156. doi: 10.1016/j.jmb.2018.07.018. Epub 2018 Jul 19.


Tryptophan-mediated Dimerization of the TssL Transmembrane Anchor Is Required for Type VI Secretion System Activity.

Zoued A, Duneau JP, Durand E, España AP, Journet L, Guerlesquin F, Cascales E.

J Mol Biol. 2018 Mar 30;430(7):987-1003. doi: 10.1016/j.jmb.2018.02.008. Epub 2018 Feb 17.


Antibacterial Weapons: Targeted Destruction in the Microbiota.

Chassaing B, Cascales E.

Trends Microbiol. 2018 Apr;26(4):329-338. doi: 10.1016/j.tim.2018.01.006. Epub 2018 Feb 13. Review.


Towards a complete structural deciphering of Type VI secretion system.

Nguyen VS, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C.

Curr Opin Struct Biol. 2018 Apr;49:77-84. doi: 10.1016/ Epub 2018 Feb 2. Review.


Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.

Leone P, Roche J, Vincent MS, Tran QH, Desmyter A, Cascales E, Kellenberger C, Cambillau C, Roussel A.

Nat Commun. 2018 Jan 30;9(1):429. doi: 10.1038/s41467-017-02784-7.


Structure-Function Analysis of the C-Terminal Domain of the Type VI Secretion TssB Tail Sheath Subunit.

Douzi B, Logger L, Spinelli S, Blangy S, Cambillau C, Cascales E.

J Mol Biol. 2018 Feb 2;430(3):297-309. doi: 10.1016/j.jmb.2017.11.015. Epub 2017 Dec 6.


Microbiology: And Amoebophilus Invented the Machine Gun!

Cascales E.

Curr Biol. 2017 Nov 6;27(21):R1170-R1173. doi: 10.1016/j.cub.2017.09.025.


TssA: The cap protein of the Type VI secretion system tail.

Zoued A, Durand E, Santin YG, Journet L, Roussel A, Cambillau C, Cascales E.

Bioessays. 2017 Oct;39(10). doi: 10.1002/bies.201600262. Epub 2017 Aug 17. Review.


Fusion Reporter Approaches to Monitoring Transmembrane Helix Interactions in Bacterial Membranes.

Logger L, Zoued A, Cascales E.

Methods Mol Biol. 2017;1615:199-210. doi: 10.1007/978-1-4939-7033-9_16.


Measure of Peptidoglycan Hydrolase Activity.

Santin YG, Cascales E.

Methods Mol Biol. 2017;1615:151-158. doi: 10.1007/978-1-4939-7033-9_12.


Probing Inner Membrane Protein Topology by Proteolysis.

Vincent MS, Cascales E.

Methods Mol Biol. 2017;1615:97-103. doi: 10.1007/978-1-4939-7033-9_8.


Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.

Nguyen VS, Logger L, Spinelli S, Legrand P, Huyen Pham TT, Nhung Trinh TT, Cherrak Y, Zoued A, Desmyter A, Durand E, Roussel A, Kellenberger C, Cascales E, Cambillau C.

Nat Microbiol. 2017 Jun 26;2:17103. doi: 10.1038/nmicrobiol.2017.103.


Inside the Chamber of Secrets of the Type III Secretion System.

Cascales E.

Cell. 2017 Mar 9;168(6):949-951. doi: 10.1016/j.cell.2017.02.028.


Characterization of the Porphyromonas gingivalis Type IX Secretion Trans-envelope PorKLMNP Core Complex.

Vincent MS, Canestrari MJ, Leone P, Stathopulos J, Ize B, Zoued A, Cambillau C, Kellenberger C, Roussel A, Cascales E.

J Biol Chem. 2017 Feb 24;292(8):3252-3261. doi: 10.1074/jbc.M116.765081. Epub 2017 Jan 5.


Domestication of a housekeeping transglycosylase for assembly of a Type VI secretion system.

Santin YG, Cascales E.

EMBO Rep. 2017 Jan;18(1):138-149. doi: 10.15252/embr.201643206. Epub 2016 Dec 5.


Molecular Dissection of the Interface between the Type VI Secretion TssM Cytoplasmic Domain and the TssG Baseplate Component.

Logger L, Aschtgen MS, Guérin M, Cascales E, Durand E.

J Mol Biol. 2016 Nov 6;428(22):4424-4437. doi: 10.1016/j.jmb.2016.08.032. Epub 2016 Sep 4.


Structure-Function Analysis of the TssL Cytoplasmic Domain Reveals a New Interaction between the Type VI Secretion Baseplate and Membrane Complexes.

Zoued A, Cassaro CJ, Durand E, Douzi B, España AP, Cambillau C, Journet L, Cascales E.

J Mol Biol. 2016 Nov 6;428(22):4413-4423. doi: 10.1016/j.jmb.2016.08.030. Epub 2016 Sep 4.


Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli.

Douzi B, Brunet YR, Spinelli S, Lensi V, Legrand P, Blangy S, Kumar A, Journet L, Cascales E, Cambillau C.

Sci Rep. 2016 Oct 4;6:34405. doi: 10.1038/srep34405.


The PorX Response Regulator of the Porphyromonas gingivalis PorXY Two-Component System Does Not Directly Regulate the Type IX Secretion Genes but Binds the PorL Subunit.

Vincent MS, Durand E, Cascales E.

Front Cell Infect Microbiol. 2016 Aug 31;6:96. doi: 10.3389/fcimb.2016.00096. eCollection 2016.


Salmonella Typhimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut.

Sana TG, Flaugnatti N, Lugo KA, Lam LH, Jacobson A, Baylot V, Durand E, Journet L, Cascales E, Monack DM.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5044-51. doi: 10.1073/pnas.1608858113. Epub 2016 Aug 8.


The Type VI Secretion System in Escherichia coli and Related Species.

Journet L, Cascales E.

EcoSal Plus. 2016 May;7(1). doi: 10.1128/ecosalplus.ESP-0009-2015. Review.


Priming and polymerization of a bacterial contractile tail structure.

Zoued A, Durand E, Brunet YR, Spinelli S, Douzi B, Guzzo M, Flaugnatti N, Legrand P, Journet L, Fronzes R, Mignot T, Cambillau C, Cascales E.

Nature. 2016 Mar 3;531(7592):59-63. doi: 10.1038/nature17182. Epub 2016 Feb 24.


Meeting report: Adaptation and communication of bacterial pathogens.

Aussel L, Beuzón CR, Cascales E.

Virulence. 2016 May 18;7(4):481-90. doi: 10.1080/21505594.2016.1152441. Epub 2016 Feb 18.


A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery.

Flaugnatti N, Le TT, Canaan S, Aschtgen MS, Nguyen VS, Blangy S, Kellenberger C, Roussel A, Cambillau C, Cascales E, Journet L.

Mol Microbiol. 2016 Mar;99(6):1099-118. doi: 10.1111/mmi.13292. Epub 2016 Feb 10.


The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization.

Brunet YR, Zoued A, Boyer F, Douzi B, Cascales E.

PLoS Genet. 2015 Oct 13;11(10):e1005545. doi: 10.1371/journal.pgen.1005545. eCollection 2015 Oct.


Biogenesis and structure of a type VI secretion membrane core complex.

Durand E, Nguyen VS, Zoued A, Logger L, Péhau-Arnaudet G, Aschtgen MS, Spinelli S, Desmyter A, Bardiaux B, Dujeancourt A, Roussel A, Cambillau C, Cascales E, Fronzes R.

Nature. 2015 Jul 30;523(7562):555-60. doi: 10.1038/nature14667. Epub 2015 Jul 22.


H-NS Silencing of the Salmonella Pathogenicity Island 6-Encoded Type VI Secretion System Limits Salmonella enterica Serovar Typhimurium Interbacterial Killing.

Brunet YR, Khodr A, Logger L, Aussel L, Mignot T, Rimsky S, Cascales E.

Infect Immun. 2015 Jul;83(7):2738-50. doi: 10.1128/IAI.00198-15. Epub 2015 Apr 27.


Inhibition of type VI secretion by an anti-TssM llama nanobody.

Nguyen VS, Logger L, Spinelli S, Desmyter A, Le TT, Kellenberger C, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C.

PLoS One. 2015 Mar 26;10(3):e0122187. doi: 10.1371/journal.pone.0122187. eCollection 2015.


Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody.

Nguyen VS, Spinelli S, Desmyter A, Le TT, Kellenberger C, Cascales E, Cambillau C, Roussel A.

Acta Crystallogr F Struct Biol Commun. 2015 Mar;71(Pt 3):266-71. doi: 10.1107/S2053230X15000709. Epub 2015 Feb 19.


Crystallization and preliminary X-ray analysis of the C-terminal fragment of PorM, a subunit of the Porphyromonas gingivalis type IX secretion system.

Stathopulos J, Cambillau C, Cascales E, Roussel A, Leone P.

Acta Crystallogr F Struct Biol Commun. 2015 Jan 1;71(Pt 1):71-4. doi: 10.1107/S2053230X1402559X. Epub 2015 Jan 1.


Transcriptional frameshifting rescues Citrobacter rodentium type VI secretion by the production of two length variants from the prematurely interrupted tssM gene.

Gueguen E, Wills NM, Atkins JF, Cascales E.

PLoS Genet. 2014 Dec 4;10(12):e1004869. doi: 10.1371/journal.pgen.1004869. eCollection 2014 Dec.


VgrG, Tae, Tle, and beyond: the versatile arsenal of Type VI secretion effectors.

Durand E, Cambillau C, Cascales E, Journet L.

Trends Microbiol. 2014 Sep;22(9):498-507. doi: 10.1016/j.tim.2014.06.004. Epub 2014 Jul 17. Review.


Architecture and assembly of the Type VI secretion system.

Zoued A, Brunet YR, Durand E, Aschtgen MS, Logger L, Douzi B, Journet L, Cambillau C, Cascales E.

Biochim Biophys Acta. 2014 Aug;1843(8):1664-73. doi: 10.1016/j.bbamcr.2014.03.018. Epub 2014 Mar 26. Review.


Crystal structure and self-interaction of the type VI secretion tail-tube protein from enteroaggregative Escherichia coli.

Douzi B, Spinelli S, Blangy S, Roussel A, Durand E, Brunet YR, Cascales E, Cambillau C.

PLoS One. 2014 Feb 14;9(2):e86918. doi: 10.1371/journal.pone.0086918. eCollection 2014.


Type VI secretion and bacteriophage tail tubes share a common assembly pathway.

Brunet YR, Hénin J, Celia H, Cascales E.

EMBO Rep. 2014 Mar;15(3):315-21. doi: 10.1002/embr.201337936. Epub 2014 Jan 31.


IHF is required for the transcriptional regulation of the Desulfovibrio vulgaris Hildenborough orp operons.

Fiévet A, Cascales E, Valette O, Dolla A, Aubert C.

PLoS One. 2014 Jan 21;9(1):e86507. doi: 10.1371/journal.pone.0086507. eCollection 2014.


Dissection of the TssB-TssC interface during type VI secretion sheath complex formation.

Zhang XY, Brunet YR, Logger L, Douzi B, Cambillau C, Journet L, Cascales E.

PLoS One. 2013 Nov 25;8(11):e81074. doi: 10.1371/journal.pone.0081074. eCollection 2013.


TssK is a trimeric cytoplasmic protein interacting with components of both phage-like and membrane anchoring complexes of the type VI secretion system.

Zoued A, Durand E, Bebeacua C, Brunet YR, Douzi B, Cambillau C, Cascales E, Journet L.

J Biol Chem. 2013 Sep 20;288(38):27031-41. doi: 10.1074/jbc.M113.499772. Epub 2013 Aug 6.


Expression of a Yersinia pseudotuberculosis Type VI Secretion System Is Responsive to Envelope Stresses through the OmpR Transcriptional Activator.

Gueguen E, Durand E, Zhang XY, d'Amalric Q, Journet L, Cascales E.

PLoS One. 2013 Jun 19;8(6):e66615. doi: 10.1371/journal.pone.0066615. Print 2013.


[Bacteraemia at a second level hospital: epidemiological study, analysis of pronostic factors associated to mortality and economic cost estimation].

Hernández-Roca JJ, García-Vázquez E, Hernández A, Canteras M, Herrero JA, Cascales E, Mené-Fenor E, Gómez-Gómez J.

Rev Esp Quimioter. 2013 Jun;26(2):119-27. Spanish.


DNA substrate-induced activation of the Agrobacterium VirB/VirD4 type IV secretion system.

Cascales E, Atmakuri K, Sarkar MK, Christie PJ.

J Bacteriol. 2013 Jun;195(11):2691-704. doi: 10.1128/JB.00114-13. Epub 2013 Apr 5.


Imaging type VI secretion-mediated bacterial killing.

Brunet YR, Espinosa L, Harchouni S, Mignot T, Cascales E.

Cell Rep. 2013 Jan 31;3(1):36-41. doi: 10.1016/j.celrep.2012.11.027. Epub 2013 Jan 3.


Energetics of colicin import revealed by genetic cross-complementation between the Tol and Ton systems.

Lloubès R, Goemaere E, Zhang X, Cascales E, Duché D.

Biochem Soc Trans. 2012 Dec 1;40(6):1480-5. doi: 10.1042/BST20120181. Review.


Promoter swapping unveils the role of the Citrobacter rodentium CTS1 type VI secretion system in interbacterial competition.

Gueguen E, Cascales E.

Appl Environ Microbiol. 2013 Jan;79(1):32-8. doi: 10.1128/AEM.02504-12. Epub 2012 Oct 12.

Supplemental Content

Loading ...
Support Center